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Clinical Use of Liquid-Based Comprehensive Genomic Profiling in Gastrointestinal Stromal Tumors Mechahougui, Hiba; Hildebrand, Lindsey; Haberberger, James; Sivakumar, Smruthy; Saiji, Essia; Tukachinsky, Hanna; Madison, Russell; Killian, Jonathan K.; Huang, Richard S. P.; Elvin, Julia A.; Marks, Eric; Heinrich, Michael C.; Koessler, Thibaud; Lin, Douglas I. Share Save
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The INSIGHT study: a randomized, Phase III study of ripretinib versus sunitinib for advanced gastrointestinal stromal tumor with KIT exon 11+17/18 mutations George, Suzanne; Blay, Jean-Yves; Chi, Ping; Jones, Robin L.; Serrano, Cesar; Somaiah, Neeta; Gelderblom, Hans; Zalcberg, John R.; Reichmann, William; Sprott, Kam; Cox, Paulina; Sherman, Matthew L.; Ruiz-Soto, Rodrigo; Heinrich, Michael C.; Bauer, Sebastian Share Save
Role of PIK3CA as a predictive biomarker in metastatic, imatinib-resistant GIST: A ct-DNA substudy of the VOYAGER trial Schardt, L. A.; Serrano, C.; Trent, J. C.; Krzeciesa, D.; Newberry, K.; Grassian, A.; Kang, Y-K.; Rutkowski, P.; Jones, R. L.; Heinrich, M.; Tap, W. D.; Pantaleo, M. A.; von Mehren, M.; Fletcher, B. S.; Muehlenberg, T.; George, S.; Mir, O.; Bauer, S. Share Save
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Asciminib monotherapy in patients with chronic-phase chronic myeloid leukemia with the T315I mutation after ≥1 prior tyrosine kinase inhibitor: 2-year follow-up results Cortes, Jorge E.; Sasaki, Koji; Kim, Dong-Wook; Hughes, Timothy P.; Etienne, Gabriel; Mauro, Michael J.; Hochhaus, Andreas; Lang, Fabian; Heinrich, Michael C.; Breccia, Massimo; Deininger, Michael; Goh, Yeow Tee; Janssen, Jeroen J. W. M.; Talpaz, Moshe; de Soria, Valle Gomez Garcia; le Coutre, Philipp; Deangelo, Daniel J.; Damon, Andrea; Cacciatore, Silvia; Polydoros, Fotis; Agrawal, Nithya; Rea, Delphine Share Save
Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial Heinrich, Michael C.; Jones, Robin L.; George, Suzanne; Gelderblom, Hans; Schoeffski, Patrick; von Mehren, Margaret; Zalcberg, John R.; Kang, Yoon-Koo; Razak, Albiruni Abdul; Trent, Jonathan; Attia, Steven; Le Cesne, Axel; Siontis, Brittany L.; Goldstein, David; Boye, Kjetil; Sanchez, Cesar; Steeghs, Neeltje; Rutkowski, Piotr; Druta, Mihaela; Serrano, Cesar; Somaiah, Neeta; Chi, Ping; Reichmann, William; Sprott, Kam; Achour, Haroun; Sherman, Matthew L.; Ruiz-Soto, Rodrigo; Blay, Jean-Yves; Bauer, Sebastian Share Save
Novel trial designs for patients with gastrointestinal stromal tumor Serrano, C.; Rothschild, S.; Villacampa, G.; Heinrich, M. C.; George, S.; Blay, J. -Y.; Sicklick, J. K.; Schwartz, G. K.; Rastogi, S.; Jones, R. L.; Rutkowski, P.; Somaiah, N.; Navarro, V.; Evans, D.; Trent, J. C. Share Save
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Clinical Benefit of Avapritinib in KIT-Mutant Gastrointestinal Stromal Tumors: A Post Hoc Analysis of the Phase I NAVIGATOR and Phase I/II CS3007-001 Studies Heinrich, Michael C.; Zhang, Xinhua; Jones, Robin L.; George, Suzanne; Serrano, Cesar; Deng, Yanhong; Bauer, Sebastian; Cai, Shirong; Wu, Xin; Zhou, Yongjian; Tao, Kaixiong; Zheng, Zhichao; Zhang, Jun; Cui, Yuehong; Cao, Hui; Wang, Meining; Hu, Jin; Yang, Jason; Li, Jian; Shen, Lin Share Save
Rethinking placebos: embracing synthetic control arms in clinical trials for rare tumors Serrano, Cesar; Rothschild, Sara; Villacampa, Guillermo; Heinrich, Michael C.; George, Suzanne; Blay, Jean-Yves; Sicklick, Jason K.; Schwartz, Gary K.; Rastogi, Sameer; Jones, Robin L.; Rutkowski, Piotr; Somaiah, Neeta; Navarro, Victor; Evans, Denisse; Trent, Jonathan C. Share Save
Patient-reported outcomes and tolerability in patients receiving ripretinib versus sunitinib after treatment with imatinib in INTRIGUE, a phase 3, open-label study1 Gelderblom, Hans; Jones, Robin L.; Blay, Jean-Yves; George, Suzanne; von Mehren, Margaret; Zalcberg, John R.; Kang, Yoon-Koo; Razak, Albiruni Abdul; Trent, Jonathan; Attia, Steven; Le Cesne, Axel; Siontis, Brittany L.; Goldstein, David; Boye, Kjetil; Sanchez, Cesar; Steeghs, Neeltje; Rutkowski, Piotr; Druta, Mihaela; Serrano, Cesar; Somaiah, Neeta; Chi, Ping; Harrow, Brooke; Becker, Claus; Reichmann, William; Sherman, Matthew L.; Ruiz-Soto, Rodrigo; Heinrich, Michael C. Share Save
Circulating tumor DNA analysis of the phase III VOYAGER trial: KIT mutational landscape and outcomes in patients with advanced gastrointestinal stromal tumor treated with avapritinib or regorafenib Serrano, C.; Bauer, S.; Gomez-Peregrina, D.; Kang, Y. -K; Jones, R. L.; Rutkowski, P.; Mir, O.; Heinrich, M. C.; Tap, W. D.; Newberry, K.; Grassian, A.; Shi, H.; Bialick, S.; Schoffski, P.; Pantaleo, M. A.; von Mehren, M.; Trent, J. C.; George, S. Share Save
A Phase I, Multicenter, Open-Label, First-in-Human Study of DS-6157a in Patients with Advanced Gastrointestinal Stromal Tumor George, Suzanne; Heinrich, Michael C.; Somaiah, Neeta; Oppelt, Peter; McLeod, Robert; Nishioka, Satoshi; Kundu, Madan G.; Qian, Xiaozhong; Kumar, Prasanna; Laadem, Abderrahmane; Lau, Yvonne; Tran, Brittany P.; Fallon, Maura; Dosunmu, Ololade; Shi, Julia; Naito, Yoichi Share Save
ATP-binding pocket substitutions as secondary or tertiary in-cis mutations are major on-target ripretinib resistance mechanisms in gastrointestinal stromal tumor Muehlenberg, Thomas; Falkenhorst, Johanna; Schulz, Tom; Fletcher, Benjamin S.; Teuber, Alina; Krzeciesa, Dawid; Klooster, Isabella; Lategahn, Jonas; Ou, Wen-Bin; Lundberg, Meijun; von Mehren, Margaret; Grunewald, Susanne; Tuns, Alicia I.; Brahmi, Mehdi; Heinrich, Michael C.; Serrano, Cesar; Schildhaus, Hans-Ulrich; Sievers, Sonja; Treckmann, Jurgen; Wilson, Lydia; Raut, Chandrajit P.; Marino-Enriquez, Adrian; George, Suzanne Share Save
Asciminib monotherapy in patients with CML-CP without BCR::ABL1 T315I mutations treated with at least two prior TKIs: 4-year phase 1 safety and efficacy results Mauro, Michael J.; Hughes, Timothy P.; Kim, Dong-Wook; Rea, Delphine; Cortes, Jorge E.; Hochhaus, Andreas; Sasaki, Koji; Breccia, Massimo; Talpaz, Moshe; Ottmann, Oliver; Minami, Hironobu; Goh, Yeow Tee; DeAngelo, Daniel J.; Heinrich, Michael C.; Gomez-Garcia de Soria, Valle; le Coutre, Philipp; Mahon, Francois-Xavier; Janssen, Jeroen J. W. M.; Deininger, Michael; Shanmuganathan, Naranie; Geyer, Mark B.; Cacciatore, Silvia; Polydoros, Fotis; Agrawal, Nithya; Hoch, Matthias; Lang, Fabian Share Save
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