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Amato J. Giaccia

university of oxford

113H-index
710Paper Count
5.2WCitation Count
Published Papers 216
Publication Date
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Tirapazamine sensitises hypoxic homologous recombination-proficient NSCLC to PARP inhibition
errCell Death Discovery
IF7
err2026-07-02
err0
errOAAI
errYanyan Jiang; Nuria Vilaplana Lopera; Hala Estephan; Yizhou Wang; Ftoon Aljarbou; Ester M. Hammond; Amato J. Giaccia; Eui Jung Moon
errShare
errSave
Tissue-specific iron levels modulate lipid peroxidation and the FLASH radiotherapy effect
errCell Death & Disease
IF9.6
err2025-09-02
err0
errOAAI
errNuria Vilaplana-Lopera; Jiyoung Kim; Gilyeong Nam; Iain D. C. Tullis; Salome Paillas; Jia-Ling Ruan; Pei Ju Lee; Yanyan Jiang; Sohee Park; Tianxu Hou; Ayesha Nasir; Eve Charlesworth; Ellie Walker; Ammar Abu-Halawa; Mark A. Hill; Changhoon Choi; Ik Jae Lee; Youngtae Jeong; Samira Lakhal-Littleton; Chee Kin Then; Shing-Chuan Shen; Amato J. Giaccia; Kristoffer Petersson; Eui Jung Moon
errShare
errSave
Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1 (vol 133, e168277, 2023)
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2024-08-15
err0
errOAAI
errBeach, Callum; MacLean, David; Majorova, Dominika; Melemenidis, Stavros; Nambiar, Dhanya K.; Kim, Ryan K.; Valbuena, Gabriel N.; Guglietta, Silvia; Krieg, Carsten; Darvish-Damavandi, Mahnaz; Suwa, Tatsuya; Easton, Alistair; Hillson, Lily V. S.; McCulloch, Ashley K.; McMahon, Ross K.; Pennel, Kathryn; Edwards, Joanne; O'Cathail, Sean M.; Roxburgh, Campbell S.; Domingo, Enric; Moon, Eui Jung; Jiang, Dadi; Jiang, Yanyan; Zhang, Qingyang; Koong, Albert C.; Woodruff, Trent M.; Graves, Edward E.; Maughan, Tim; Buczacki, Simon J. A.; Stucki, Manuel; Le, Quynh-Thu; Leedham, Simon J.; Giaccia, Amato J.; Olcina, Monica M.
errShare
errSave
Osteoblastic erythropoietin is not required for bone mass accrual
errJBMR PLUS
IF2.4
err2024-04-15
err1
errOAAI
errLanzolla, Giulia; Merceron, Christophe; Khan, Mohd Parvez; Sabini, Elena; Giaccia, Amato; Schipani, Ernestina
errShare
errSave
Tirapazamine sensitizes homologous recombination-proficient cancers by enhancing DNA damage andferroptosis
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errJiang, Yanyan; Estephan, Hala; Wang, Yizhou; Aljarbou, Ftoon; Lopera, Nuria V.; Moon, Eui Jung; Hammond, Ester M.; Giaccia, Amato J.
errShare
errSave
Therapeutic targeting of the functionally elusive TAM receptor family
errNATURE REVIEWS DRUG DISCOVERY
IF101.8
err2023-12-13
err8
errOAAI
errMiao, Yu Rebecca; Rankin, Erinn B.; Giaccia, Amato J.
errShare
errSave
Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2023-12-01
err3
errOAAI
errBeach, Callum; MacLean, David; Majorova, Dominika; Melemenidis, Stavros; Nambiar, Dhanya K.; Kim, Ryan K.; Valbuena, Gabriel N.; Guglietta, Silvia; Krieg, Carsten; Darvish-Damavandi, Mahnaz; Suwa, Tatsuya; Easton, Alistair; Hillson, Lily V. S.; McCulloch, Ashley K.; McMahon, Ross K.; Pennel, Kathryn; Edwards, Joanne; O'Cathail, Sean M.; Roxburgh, Campbell S.; Domingo, Enric; Moon, Eui Jung; Jiang, Dadi; Jiang, Yanyan; Zhang, Qingyang; Koong, Albert C.; Woodruff, Trent M.; Graves, Edward E.; Maughan, Tim; Buczacki, Simon J. A.; Stucki, Manuel; Le, Quynh-Thu; Leedham, Simon J.; Giaccia, Amato J.; Olcina, Monica M.
errShare
errSave
Hypoxia-mediated regulation of DDX5 through decreased chromatin accessibility and post-translational targeting restricts R-loop accumulation
errMOLECULAR ONCOLOGY
IF4.5
err2023-04-22
err10
errOAAI
errLeszczynska, Katarzyna B.; Dzwigonska, Monika; Estephan, Hala; Moehlenbrink, Jutta; Bowler, Elizabeth; Giaccia, Amato J.; Mieczkowski, Jakub; Kaminska, Bozena; Hammond, Ester M.
errShare
errSave
Transformed cells require continuous activity of RNA polymerase II to resist oncogene-induced apoptosis
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-29
err81
errOAAI
errKoumenis, C; Giaccia, A
errShare
errSave
p21Cip1 and p27Kip1 regulate cell cycle reentry after hypoxic stress but are not necessary for hypoxia-induced arrest
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err109
errOAAI
errGreen, SL; Freiberg, RA; Giaccia, AJ
errShare
errSave
Regulation of p53 by hypoxia: Dissociation of transcriptional repression and apoptosis from p53-dependent transactivation
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err349
errOAAI
errKoumenis, C; Alarcon, R; Hammond, E; Sutphin, P; Hoffman, W; Murphy, M; Derr, J; Taya, Y; Lowe, SW; Kastan, M; Giaccia, A
errShare
errSave
Caveolin 1-mediated regulation of receptor tyrosine kinase-associated phosphatidylinositol 3-kinase activity by ceramide
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err175
errOAAI
errZundel, W; Swiersz, LM; Giaccia, A
errShare
errSave
Highly conserved RNA sequences that are sensors of environmental stress
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err61
errOAAI
errSpicher, A; Guicherit, OM; Duret, L; Aslanian, A; Sanjines, EM; Denko, NC; Giaccia, AJ; Blau, HM
errShare
errSave
Regulation of hypoxia-inducible factor 1α expression and function by the mammalian target of rapamycin
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err1.2K
errOAAI
errHudson, CC; Liu, M; Chiang, GG; Otterness, DM; Loomis, DC; Kaper, F; Giaccia, AJ; Abraham, RT
errShare
errSave
Hypoxia links ATR and p53 through replication arrest
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err298
errOAAI
errHammond, EM; Denko, NC; Dorie, MJ; Abraham, RT; Giaccia, AJ
errShare
errSave
Adaptive myogenesis under hypoxia
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err139
errOAAI
errYun, Z; Lin, Q; Giaccia, AJ
errShare
errSave
Genome-wide analysis of p53 under hypoxic conditions
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err86
errOAAI
errHammond, EM; Mandell, DJ; Salim, A; Krieg, AJ; Johnson, TM; Shirazi, HA; Attardi, LD; Giaccia, AJ
errShare
errSave
DNA damage during reoxygenation elicits a Chk2-dependent checkpoint response
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err62
errOAAI
errFreiberg, RA; Hammond, EM; Dorie, MJ; Welford, SM; Giaccia, AJ
errShare
errSave
Functional analysis of p53 binding under differential stresses
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err71
errOAAI
errKrieg, Adam J.; Hammond, Ester M.; Giaccia, Amato J.
errShare
errSave
Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1α (HIF-1α):: Role of cytoplasmic trapping of HIF-2α
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err174
errOAAI
errPark, SK; Dadak, AM; Haase, VH; Fontana, L; Giaccia, AJ; Johnson, RS
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Irving L. Weissman
H-index: 215 · Papers: 1.3K
G
Gregg L. Semenza
H-index: 185 · Papers: 682
P
P. Andrew Futreal
H-index: 159 · Papers: 1.3K
S
Sanjiv S. Gambhir
H-index: 143 · Papers: 1.4K
E
Eugene C. Butcher
H-index: 140 · Papers: 426
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