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SaveTumor-intrinsic expression of the autophagy gene Atg16l1 suppresses anti-tumor immunity in colorectal cancer
Taraborrelli, Lucia; Senbabaoglu, Yasin; Wang, Lifen; Lim, Junghyun; Blake, Kerrigan; Kljavin, Noelyn; Gierke, Sarah; Scherl, Alexis; Ziai, James; Mcnamara, Erin; Owyong, Mark; Rao, Shilpa; Calviello, Aslihan Karabacak; Oreper, Daniel; Jhunjhunwala, Suchit; Argiles, Guillem; Bendell, Johanna; Kim, Tae Won; Ciardiello, Fortunato; Wongchenko, Matthew J.; de Sauvage, Frederic J.; Melo, Felipe; Yan, Yibing; West, Nathaniel R.; Murthy, Aditya Share Save Adrenergic nerves regulate intestinal regeneration through IL-22 signaling from type 3 innate lymphoid cellsWang, Putianqi; Kljavin, Noelyn; Nguyen, Thi Thu Thao; Storm, Elaine E.; Marsh, Bryan; Jiang, Jian; Lin, William; Menon, Hari; Piskol, Robert; de Sauvage, Frederic J. Share Save Share Save Share Save Obligate role for Rock1 and Rock2 in adult stem cell viability and functionSambandam, Arivazhagan; Storm, Elaine; Tauc, Helen; Hackney, Jason A.; Garfield, David; Caplazi, Patrick; Liu, John; Zhang, Juan; Zhang, Hua; Duggan, Jeff; Jeet, Surinder; Gierke, Sarah; Chang, Patrick; Wu, Xiumin; Newman, Robert; Tam, Lucinda; Alcantar, Tuija; Wang, Lifen; Roose-Girma, Meron; Modrusan, Zora; Lee, Wyne P.; Jasper, Heinrich; de Sauvage, Frederic; Pappu, Rajita Share Save Disruption of stem cell niche-confined R-spondin 3 expression leads to impaired hematopoiesisKurtova, Antonina, V; Heinlein, Melanie; Haas, Simon; Velten, Lars; Dijkgraaf, Gerrit J. P.; Storm, Elaine E.; Kljavin, Noelyn M.; Boumahdi, Soufiane; Himmels, Patricia; Herault, Aurelie; Mancini, Andrew; Koeppen, Hartmut; Dail, Monique; Yan, Qingxiang; Zhang, Jianhuan; Koch, Ute; Radtke, Freddy; Modrusan, Zora; Metcalfe, Ciara; Piskol, Robert; de Sauvage, Frederic J. Share Save Directed evolution identifies high-affinity cystine-knot peptide agonists and antagonists of Wnt/β-catenin signalingHansen, Simon; Zhang, Yingnan; Hwang, Sunhee; Nabhan, Ahmad; Li, Wanqing; Fuhrmann, Jakob; Kschonsak, Yvonne; Zhou, Lijuan; Nile, Aaron H.; Gao, Xinxin; Piskol, Robert; de Sousa e Melo, Felipe; de Sauvage, Frederic J.; Hannoush, Rami N. Share Save IL-1R1-dependent signaling coordinates epithelial regeneration in response to intestinal damageCox, Christian B.; Storm, Elaine E.; Kapoor, Varun N.; Chavarria-Smith, Joseph; Lin, David L.; Wang, Lifen; Li, Yun; Kljavin, Noelyn; Ota, Naruhisa; Bainbridge, Travis W.; Anderson, Keith; Roose-Girma, Merone; Warming, Soren; Arron, Joseph R.; Turley, Shannon J.; de Sauvage, Frederic J.; Campagne, Menno van Lookeren Share Save Gremlin 1+ fibroblastic niche maintains dendritic cell homeostasis in lymphoid tissuesKapoor, Varun N.; Muller, Soren; Keerthivasan, Shilpa; Brown, Markus; Chalouni, Cecile; Storm, Elaine E.; Castiglioni, Alessandra; Lane, Ryan; Nitschke, Maximilian; Dominguez, Claudia X.; Astarita, Jillian L.; Krishnamurty, Akshay T.; Carbone, Catherine B.; Senbabaoglu, Yasin; Wang, Amber W.; Wu, Xiumin; Cremasco, Viviana; Roose-Girma, Merone; Tam, Lucinda; Doerr, Jonas; Chen, Mark Z.; Lee, Wyne P.; Modrusan, Zora; Yang, Yeqing Angela; Bourgon, Richard; Sandoval, Wendy; Shaw, Andrey S.; de Sauvage, Frederic J.; Mellman, Ira; Moussion, Christine; Turley, Shannon J. Share Save Share Save Share Save Lgr5+telocytes are a signaling source at the intestinal villus tipBahar Halpern, Keren; Massalha, Hassan; Zwick, Rachel K.; Moor, Andreas E.; Castillo-Azofeifa, David; Rozenberg, Milena; Farack, Lydia; Egozi, Adi; Miller, Dan R.; Averbukh, Inna; Harnik, Yotam; Weinberg-Corem, Noa; de Sauvage, Frederic J.; Amit, Ido; Klein, Ophir D.; Shoshkes-Carmel, Michal; Itzkovitz, Shalev Share Save Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling GradientMcCarthy, Neil; Manieri, Elisa; Storm, Elaine E.; Saadatpour, Assieh; Luoma, Adrienne M.; Kapoor, Varun N.; Madha, Shariq; Gaynor, Liam T.; Cox, Christian; Keerthivasan, Shilpa; Wucherpfennig, Kai; Yuan, Guo-Cheng; de Sauvage, Frederic J.; Turley, Shannon J.; Shivdasani, Ramesh A. Share Save Share Save A Clinically Applicable Gene-Expression Classifier Reveals Intrinsic and Extrinsic Contributions to Consensus Molecular Subtypes in Primary and Metastatic Colon CancerPiskol, Robert; Huw, Ling; Sergin, Ismail; Kljin, Christiaan; Modrusan, Zora; Kim, Doris; Kljavin, Noelyn; Tam, Rachel; Patel, Rajesh; Burton, Jeremy; Penuel, Elicia; Qu, Xueping; Koeppen, Hartmut; Sumiyoshi, Teiko; de Sauvage, Frederic; Lackner, Mark R.; de Sousa e Melo, Felipe; Kabbarah, Omar Share Save NRG1 is a critical regulator of differentiation in TP63-driven squamous cell carcinomaHegde, Ganapati V.; de la Cruz, Cecile; Giltnane, Jennifer M.; Crocker, Lisa; Venkatanarayan, Avinashnarayan; Schaefer, Gabriele; Dunlap, Debra; Hoeck, Joerg D.; Piskol, Robert; Gnad, Florian; Modrusan, Zora; de Sauvage, Frederic J.; Siebel, Christian W.; Jackson, Erica L. Share Save Share Save Share Save Subtle Changes in the Levels of BCL-2 Proteins Cause Severe Craniofacial AbnormalitiesGrabow, Stephanie; Kueh, Andrew J.; Ke, Francine; Vanyai, Hannah K.; Sheikh, Bilal N.; Dengler, Michael A.; Chiang, William; Eccles, Samantha; Smyth, Ian M.; Jones, Lynelle K.; de Sauvage, Frederic J.; Scott, Mark; Whitehead, Lachlan; Voss, Anne K.; Strasser, Andreas Share Save 
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