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J

James R. Heath

Institute for Systems Biology

108H-index
603Paper Count
5.2WCitation Count
Published Papers 159
Publication Date
Whole-protein screening and multi-modal profiling of antigen-specific CD4+ T cells at single-cell resolution
err2026-05-12
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errRongyu Zhang; Jingqi Qi; Michaela McKasson; Jongchan Choi; Vanessa Gutierrez; Conor Brennan; Sunga Hong; William Chour; Rachel H. Ng; Jingyi Xie; Dan Yuan; Andrew Webster; Simranjeet K. Sidhu; Abby Anderson; Daniel Chen; Rick Edmark; Kim M. Murray; Sarah Li; Connor McDonald; Lee Rowen; Shuo Wang; Yusuf Rasheed; Yapeng Su; Jamie R. Wagner; Jia Ming Chen; Karla Nawaly; Jie Fu; Alexandria Duven; Stephen J. Forman; Mihae Song; Saul J. Priceman; Christine E. Brown; Antoni Ribas; Deborah J. Wong; Kelly G. Paulson; Charles W. Drescher; Cristina Puig-Saus; Jason D. Goldman; Cornelia L. Trimble; James R. Heath
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Sequential transcriptional waves and NF-κB-driven chromatin remodeling direct drug-induced dedifferentiation in cancer
err2026-04-15
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errYapeng Su; Chunmei Liu; Xiang Lu; Hui-Yu Chuang; Guideng Li; Shiqun Shao; Yan Kong; Jihoon W. Lee; Rachel H. Ng; Stephanie Wong; Lidia Robert; Charles Warden; Victoria Liu; Jie Chen; Zhuo Wang; Guangrong Qin; Yin Tang; Hanjun Cheng; Alphonsus H. C. Ng; Daniel Chen; Songming Peng; Min Xue; Dazy Johnson; Yu Xu; Jinhui Wang; Xiwei Wu; Ilya Shmulevich; Qihui Shi; Raphael Levine; Antoni Ribas; David Baltimore; Jun Guo; James R. Heath; Wei Wei
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Long COVID trajectories in the prospectively followed RECOVER-Adult US cohort
err2025-11-17
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errTanayott Thaweethai; Sarah E. Donohue; Jeffrey N. Martin; Mady Hornig; Jarrod M. Mosier; Daniel J. Shinnick; Hassan Ashktorab; Ornina Atieh; Andra Blomkalns; Hassan Brim; Yu Chen; Melissa M. Cortez; Nathan B. Erdmann; Valerie Flaherman; Paul Goepfert; Jason D. Goldman; Naomi M. Hamburg; Jenny E. Han; James R. Heath; Vanessa Jacoby; Sarah E. Jolley; J. Daniel Kelly; Sara W. Kelly; C. Kim; Jerry A. Krishnan; Rebecca Letts; Emily B. Levitan; Matthew E. Modes; Grace A. McComsey; Torri D. Metz; Janet M. Mullington; Igho Ofotokun; Megumi J. Okumura; Claudia Castillo Paredes; Thomas F. Patterson; Michael J. Peluso; Rebecca Reece; Zaki A. Sherif; Hyagriv N. Simhan; Christopher Simmons; Upinder Singh; Barbara S. Taylor; Brittany D. Taylor; Joel D. Trinity; Andrea B. Troxel; Paul J. Utz; Andrew J. Vasey; Elisheva Weinberger; Zanthia Wiley; Juan Wisnivesky; Lynn M. Yee; Leora Horwitz; Andrea S. Foulkes; Bruce D. Levy
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Cytokines Associated With Moderate and Severe Adverse Events During a Sporozoite Malaria Vaccine Trial With Controlled Human Malaria Infection
err2025-08-01
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PREAI
errJatt, Lauren P.; Gillespie, Kevin M.; Van, Phuong; Hoffman, Stephen L.; Jackson, Lisa A.; Murphy, Sean C.; Heath, James R.; Kublin, James G.
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A conserved immune dysregulation signature is associated with infection severity, risk factors prior to infection, and treatment response
errImmunity
IF26.3
err2025-06-17
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errAnanthakrishnan Ganesan; Andrew R. Moore; Hong Zheng; Jiaying Toh; Michael Freedman; Andrew T. Magis; James R. Heath; Purvesh Khatri
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Signaling and transcriptional dynamics underlying early adaptation to oncogenic BRAF inhibition
err2025-04-01
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errFlower, Cameron T.; Liu, Chunmei; Chuang, Hui-Yu; Ye, Xiaoyang; Cheng, Hanjun; Health, James R.; Wei, Wei; White, Forest M.
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CITE-Seq Analysis Reveals a Differential Natural Killer Cell SPON2 Expression in Cardiovascular Disease Patients Impacted by Human-Cytomegalovirus Serostatus and Diabetes
err2025-02-06
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errArmstrong, Sujit Silas; Chen, Daniel G.; Kumar, Sunil; Heath, James R.; Feinstein, Matthew J.; Greenland, John R.; Calabrese, Daniel R.; Lanier, Lewis L.; Ley, Klaus; Shemesh, Avishai
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Multi-Omic characterization of the effects of Ocrelizumab in patients with relapsing-remitting multiple sclerosis
err2024-12-01
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PREAI
errKornilov, Sergey A.; Price, Nathan D.; Gelinas, Richard; Acosta, Juan; Brunkow, Mary E.; Gervasi-Follmar, Tiffany; Winger, Ryan C.; Aldershoff, Dmitri; Lausted, Christopher; Troisch, Pamela; Smith, Brett; Heath, James R.; Repovic, Pavle; Cohan, Stanley; Magis, Andrew T.
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Integrated Antigenic and Nucleic Acid Detection in Single Virions and Extracellular Vesicles with Viral Content
err2024-06-23
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PREAI
errNguyen, Kim Truc; Rima, Xilal Y.; Nguyen, Luong T. H.; Wang, Xinyu; Kwak, Kwang Joo; Yoon, Min Jin; Li, Hong; Chiang, Chi-Ling; Doon-Ralls, Jacob; Scherler, Kelsey; Fallen, Shannon; Godfrey, Stephanie L.; Wallick, Julie A.; Magana, Setty M.; Palmer, Andre F.; Lee, Inyoul; Nunn, Christopher C.; Reeves, Kimberly M.; Kaplan, Henry G.; Goldman, Jason D.; Heath, James R.; Wang, Kai; Pancholi, Preeti; Lee, L. James; Reategui, Eduardo
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Integrative systems biology reveals NKG2A-biased immune responses correlate with protection in infectious disease, autoimmune disease, and cancer
err2024-03-01
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errChen, Daniel G.; Xie, Jingyi; Choi, Jongchan; Ng, Rachel H.; Zhang, Rongyu; Li, Sarah; Edmark, Rick; Zheng, Hong; Solomon, Ben; Campbell, Katie M.; Medina, Egmidio; Ribas, Antoni; Khatri, Purvesh; Lanier, Lewis L.; Mease, Philip J.; Goldman, Jason D.; Su, Yapeng; Heath, James R.
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Non-mass spectrometric targeted single-cell metabolomics
err2023-11-01
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errCheng, Hanjun; Tang, Yin; Li, Zhonghan; Guo, Zhili; Heath, James R.; Xue, Min; Wei, Wei
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Organ-specific immunity: A tissue analysis framework for investigating local immune responses to SARS-CoV-2
err2023-10-01
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errNg, Alphonsus H. C.; Hu, Huiqian; Wang, Kai; Scherler, Kelsey; Warren, Sarah E.; Zollinger, Daniel R.; McKay-Fleisch, Jill; Sorg, Kristina; Beechem, Joseph M.; Ragaglia, Emily; Lacy, J. Matthew; Smith, Kelly D.; Marshall, Desiree A.; Bundesmann, Michael M.; de Castilla, Diego Lopez; Corwin, David; Yarid, Nicole; Knudsen, Beatrice S.; Lu, Yue; Goldman, Jason D.; Heath, James R.
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Stereochemical engineering yields a multifunctional peptide macrocycle inhibitor of Akt2 by fine-tuning macrocycle-cell membrane interactions
err2023-05-18
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errNag, Arundhati; Mafi, Amirhossein; Das, Samir; Yu, Mary Beth; Alvarez-Villalonga, Belen; Kim, Soo-Kyung; Su, Yapeng; Goddard, William A., III; Heath, James R.
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Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+T cell discovery and analysis
err2023-05-16
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errChour, William; Choi, Jongchan; Xie, Jingyi; Chaffee, Mary E. E.; Schmitt, Thomas M. M.; Finton, Kathryn; DeLucia, Diana C. C.; Xu, Alexander M. M.; Su, Yapeng; Chen, Daniel G. G.; Zhang, Rongyu; Yuan, Dan; Hong, Sunga; Ng, Alphonsus H. C.; Butler, Jonah Z. Z.; Edmark, Rick A. A.; Jones, Lesley C. C.; Murray, Kim M. K. M.; Peng, Songming; Li, Guideng; Strong, Roland K. K.; Lee, John K. K.; Goldman, Jason D. D.; Greenberg, Philip D. D.; Heath, James R. R.
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Effects of HLA single chain trimer design on peptide presentation and stability
err2023-05-03
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errFinton, Kathryn A. K.; Rupert, Peter B.; Friend, Della J.; Dinca, Ana; Lovelace, Erica S.; Buerger, Matthew; Rusnac, Domnita V.; Foote-McNabb, Ulysses; Chour, William; Heath, James R.; Campbell, Jean S.; Pierce, Robert H.; Strong, Roland K.
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Prediction of HLA genotypes from single-cell transcriptome data
err2023-04-25
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errSolomon, Benjamin D.; Zheng, Hong; Dillon, Laura W.; Goldman, Jason D.; Hourigan, Christopher S.; Heath, James R.; Khatri, Purvesh
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A systems pharmacology approach to discover synergistic targeted therapy combinations
err2023-04-04
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PREAI
errFlower, Cameron T.; Liu, Chunmei; Heath, James R.; Wei, Wei; White, Forest M.
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