Not logged inInhibition of mitochondrial folate metabolism drives differentiation through mTORC1 mediated purine sensing
Zarou, Martha M.; Rattigan, Kevin M.; Sarnello, Daniele; Shokry, Engy; Dawson, Amy; Ianniciello, Angela; Dunn, Karen; Copland, Mhairi; Sumpton, David; Vazquez, Alexei; Helgason, G. Vignir .png)
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SaveShare Save Share Save Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasisKiweler, Nicole; Delbrouck, Catherine; Pozdeev, Vitaly, I; Neises, Laura; Soriano-Baguet, Leticia; Eiden, Kim; Xian, Feng; Benzarti, Mohaned; Haase, Lara; Koncina, Eric; Schmoetten, Maryse; Jaeger, Christian; Noman, Muhammad Zaeem; Vazquez, Alexei; Janji, Bassam; Dittmar, Gunnar; Brenner, Dirk; Letellier, Elisabeth; Meiser, Johannes Share Save Share Save Share Save Share Save Share Save Share Save Share Save Formate induces a metabolic switch in nucleotide and energy metabolismOizel, Kristell; Tait-Mulder, Jacqueline; Fernandez-de-Cossio-Diaz, Jorge; Pietzke, Matthias; Brunto, Holly; Lilla, Sergio; Dhayade, Sandeep; Athineos, Dimitri; Blanco, Giovanny Rodriguez; Sumpton, David; Mackay, Gillian M.; Blyth, Karen; Zanivan, Sara R.; Meiser, Johannes; Vazquez, Alexei Share Save Share Save Targeting the Metabolic Response to Statin-Mediated Oxidative Stress Produces a Synergistic Antitumor ResponseMcGregor, Grace H.; Campbell, Andrew D.; Fey, Sigrid K.; Tumanov, Sergey; Sumpton, David; Blanco, Giovanny Rodriguez; Mackay, Gillian; Nixon, Colin; Vazquez, Alexei; Sansom, Owen J.; Kamphorst, Jurre J. Share Save Share Save Share Save Increased formate overflow is a hallmark of oxidative cancerMeiser, Johannes; Schuster, Anne; Pietzke, Matthias; Vande Voorde, Johan; Athineos, Dimitris; Oizel, Kristell; Burgos-Barragan, Guillermo; Wit, Niek; Dhayade, Sandeep; Morton, Jennifer P.; Dornier, Emmanuel; Sumpton, David; Mackay, Gillian M.; Blyth, Karen; Patel, Ketan J.; Niclou, Simone P.; Vazquez, Alexei Share Save Share Save Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum LimitationBulusu, Vinay; Tumanov, Sergey; Michalopoulou, Evdokia; van den Broek, Niels J.; MacKay, Gillian; Nixon, Colin; Dhayade, Sandeep; Schug, Zachary T.; Voorde, Johan Vande; Blyth, Karen; Gottlieb, Eyal; Vazquez, Alexei; Kamphorst, Jurre J. Share Save Serine one-carbon catabolism with formate overflowMeiser, Johannes; Tumanov, Sergey; Maddocks, Oliver; Labuschagne, Christiaan Fred; Athineos, Dimitris; Van Den Broek, Niels; Mackay, Gillian M.; Gottlieb, Eyal; Blyth, Karen; Vousden, Karen; Kamphorst, Jurre J.; Vazquez, Alexei Share Save Share Save 
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