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Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase-2 (SHP2) (vol 67, pg 4655, 2024) Day, James E. H.; Berdini, Valerio; Castro, Joan; Chessari, Gianni; Davies, Thomas G.; Day, Philip J.; Denis, Jeffrey D. St; Fujiwara, Hideto; Fukaya, Satoshi; Hamlett, Christopher C. F.; Hearn, Keisha; Hiscock, Steven D.; Holvey, Rhian S.; Ito, Satoru; Kandola, Navrohit; Kodama, Yasuo; Liebeschuetz, John W.; Martins, Vanessa; Matsuo, Kenichi; Mortenson, Paul N.; Muench, Sandra; Nakatsuru, Yoko; Ochiiwa, Hiroaki; Palmer, Nicholas; Peakman, Torren; Price, Amanda; Reader, Michael; Rees, David C.; Rich, Sharna J.; Shah, Alpesh; Shibata, Yoshihiro; Smyth, Tomoko; Twigg, David G.; Wallis, Nicola G.; Williams, Glyn; Wilsher, Nicola E.; Woodhead, Andrew; Shimamura, Tadashi; Johnson, Christopher N. Share Save
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Discovery of ASTX295, a potent, next-generation small molecule antagonist of MDM2 with differentiated pharmacokinetic profile Ahn, Maria; Bevan, Luke; Buck, Ildiko; Cano, Celine; Castro, Juan; Cons, Ben; Endicott, Jane; Fazal, Lynsey; Ferrari, Nicola; Hardcastle, Ian; Hearn, Keisha; Holvey, Rhian; Howard, Steven; Johnson, Chris; Jennings, Claire; Kucia-Tran, Justyna; Kyle, Suzanne; Lunec, John; Lyons, John; Miller, Duncan; Rees, David; Noble, Martin; Newell, David R.; Reeks, Judith; Saini, Harpreet; Denis, Jeffrey St.; Tamanini, Emiliano; Thomas, Huw; Thompson, Neil; Vinkovic, Mladen; Ward, George; Wallis, Nicola; Walton, Hugh; Wedge, Stephen; Williams, Pamela; Willmore, Elaine; Wilshire, Nicola; Zhao, Yan; Chessari, Gianni Share Save
Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase-2 (SHP2) Day, James E. H.; Berdini, Valerio; Castro, Joan; Chessari, Gianni; Davies, Thomas G.; Day, Philip J.; St. Denis, Jeffrey D.; Fujiwara, Hideto; Fukaya, Satoshi; Hamlett, Christopher C. F.; Hearn, Keisha; Hiscock, Steven D.; Holvey, Rhian S.; Ito, Satoru; Kandola, Navrohit; Kodama, Yasuo; Liebeschuetz, John W.; Martins, Vanessa; Matsuo, Kenichi; Mortenson, Paul N.; Muench, Sandra; Nakatsuru, Yoko; Ochiiwa, Hiroaki; Palmer, Nicholas; Peakman, Torren; Price, Amanda; Reader, Michael; Rees, David C.; Rich, Sharna J.; Shah, Alpesh; Shibata, Yoshihiro; Smyth, Tomoko; Twigg, David G.; Wallis, Nicola G.; Williams, Glyn; Wilsher, Nicola E.; Woodhead, Andrew; Shimamura, Tadashi; Johnson, Christopher N. Share Save
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Invasive Bacterial Infections in Children With Sickle Cell Disease: 2014-2019 Gaschignard, Jean; Koehl, Berengere; Rees, David C.; Rincon-Lopez, Elena; Vanderfaeillie, Anna; Pascault, Alice; Allali, Slimane; Cela, Elena; Odievre, Marie-Helene; Hau, Isabelle; Oliveira, Marisa; Guillaumat, Cecile; Brousse, Valentine; de Montalembert, Mariane; Gomez, Maria Luisa Navarro; Beldjoudi, Naima; Bardon-Cancho, Eduardo Jesus; Epalza, Cristina Share Save
Males with sickle cell disease have higher risks of cerebrovascular disease, increased inflammation, and a reduced response to hydroxyurea Di Mauro, Margherita; El Hoss, Sara; Nardo-Marino, Amina; Stuart-Smith, Sara; Strouboulis, John; Gibson, John S.; Rees, David C.; Brewin, John N. Share Save
Defining global strategies to improve outcomes in sickle cell disease: a Lancet Haematology Commission Piel, Frederic B.; Rees, David C.; DeBaun, Michael R.; Nnodu, Obiageli; Ranque, Brigitte; Thompson, Alexis A.; Ware, Russell E.; Abboud, Miguel R.; Abraham, Allistair; Ambrose, Emmanuela E.; Andemariam, Biree; Colah, Roshan; Colombatti, Raffaella; Conran, Nicola; Costa, Fernando F.; Cronin, Robert M.; de Montalembert, Mariane; Elion, Jacques; Esrick, Erica; Greenway, Anthea L.; Idris, Ibrahim M.; Issom, David-Zacharie; Jain, Dipty; Jordan, Lori C.; Kaplan, Zane S.; King, Allison A.; Lloyd-Puryear, Michele; Oppong, Samuel A.; Sharma, Akshay; Sung, Lillian; Tshilolo, Leon; Wilkie, Diana J.; Ohene-Frempong, Kwaku Share Save
Structural connectivity mediates the relationship between blood oxygenation and cognitive function in sickle cell anemia Clayden, Jonathan D.; Stotesbury, Hanne; Kawadler, Jamie M.; Slee, April; Kolbel, Melanie; Saunders, Dawn E.; Hood, Anna M.; Wilkey, Olu; Layton, Mark; Inusa, Baba; Pelidis, Maria; Chakravorty, Subarna; Rees, David C.; Howard, Jo; Awogbade, Moji; Liossi, Christina; Kirkham, Fenella J.; Clark, Chris A. Share Save
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