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SaveTryptophan fuels MYC-dependent liver tumorigenesis through indole 3-pyruvate synthesis
Venkateswaran, Niranjan; Garcia, Roy; Lafita-Navarro, M. Carmen; Hao, Yi-Heng; Perez-Castro, Lizbeth; Nogueira, Pedro A. S.; Solmonson, Ashley; Mender, Ilgen; Kilgore, Jessica A.; Fang, Shun; Brown, Isabella N.; Li, Li; Parks, Emily; dos Santos, Igor Lopes; Bhaskar, Mahima; Kim, Jiwoong; Jia, Yuemeng; Lemoff, Andrew; Grishin, Nick V.; Kinch, Lisa; Xu, Lin; Williams, Noelle S.; Shay, Jerry W.; Deberardinis, Ralph J.; Zhu, Hao; Conacci-Sorrell, Maralice Share Save A telomere-targeting drug depletes cancer initiating cells and promotes anti-tumor immunity in small cell lung cancerEglenen-Polat, Buse; Kowash, Ryan R.; Huang, Hai-Cheng; Siteni, Silvia; Zhu, Mingrui; Chen, Kenian; Bender, Matthew E.; Mender, Ilgen; Stastny, Victor; Drapkin, Benjamin J.; Raj, Prithvi; Minna, John D.; Xu, Lin; Shay, Jerry W.; Akbay, Esra A. Share Save Alternative lengthening of telomeres (ALT) cells viability is dependent on C-rich telomeric RNAsRosso, Ilaria; Jones-Weinert, Corey; Rossiello, Francesca; Cabrini, Matteo; Brambillasca, Silvia; Munoz-Sagredo, Leonel; Lavagnino, Zeno; Martini, Emanuele; Tedone, Enzo; Garre, Massimiliano; Aguado, Julio; Parazzoli, Dario; Mione, Marina; Shay, Jerry W.; Mercurio, Ciro; di Fagagna, Fabrizio d'Adda Share Save Structural basis for high-order complex of SARNP and DDX39B to facilitate mRNP assemblyXie, Yihu; Gao, Shengyan; Zhang, Ke; Bhat, Prasanna; Clarke, Bradley P.; Batten, Kimberly; Mei, Menghan; Gazzara, Matthew; Shay, Jerry W.; Lynch, Kristen W.; Angelos, Alexia E.; Hill, Pate S.; Ivey, Austin L.; Fontoura, Beatriz M. A.; Ren, Yi Share Save Genetic and clinical determinants of telomere lengthAllaire, Patrick; He, Jing; Mayer, John; Moat, Luke; Gerstenberger, Peter; Wilhorn, Reynor; Strutz, Sierra; Kim, David S. L.; Zeng, Chenjie; Cox, Nancy; Shay, Jerry W.; Denny, Joshua; Bastarache, Lisa; Hebbring, Scott Share Save Influenza virus mRNAs encode determinants for nuclear export via the cellular TREX-2 complexBhat, Prasanna; Aksenova, Vasilisa; Gazzara, Matthew; Rex, Emily A.; Aslam, Sadaf; Haddad, Christina; Gao, Shengyan; Esparza, Matthew; Cagatay, Tolga; Batten, Kimberly; El Zahed, Sara S.; Arnaoutov, Alexei; Zhong, Hualin; Shay, Jerry W.; Tolbert, Blanton S.; Dasso, Mary; Lynch, Kristen W.; Garcia-Sastre, Adolfo; Fontoura, Beatriz M. A. Share Save Activating an Adaptive Immune Response with a Telomerase-Mediated Telomere Targeting Therapeutic in Hepatocellular CarcinomaMender, Ilgen; Siteni, Silvia; Barron, Summer; Flusche, Ann Marie; Kubota, Naoto; Yu, Chunhua; Cornelius, Crystal; Tedone, Enzo; Maziveyi, Mazvita; Grichuk, Anthony; Venkateswaran, Niranjan; Conacci-Sorrell, Maralice; Hoshida, Yujin; Kang, Rui; Tang, Daolin; Gryaznov, Sergei; Shay, Jerry W. Share Save Share Save Share Save Share Save Share Save Share Save Share Save Share Save Disruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human CellsKulak, Ozlem; Chen, Hua; Holohan, Brody; Wu, Xiaofeng; He, Huawei; Borek, Dominika; Otwinowski, Zbyszek; Yamaguchi, Kiyoshi; Garofalo, Lauren A.; Ma, Zhiqiang; Wright, Woodring; Chen, Chuo; Shay, Jerry W.; Zhang, Xuewu; Lum, Lawrence Share Save Lamin A/C Depletion Enhances DNA Damage-Induced Stalled Replication Fork ArrestSingh, Mayank; Hunt, Clayton R.; Pandita, Raj K.; Kumar, Rakesh; Yang, Chin-Rang; Horikoshi, Nobuo; Bachoo, Robert; Serag, Sara; Story, Michael D.; Shay, Jerry W.; Powell, Simon N.; Gupta, Arun; Jeffery, Jessie; Pandita, Shruti; Chen, Benjamin P. C.; Deckbar, Dorothee; Loebrich, Markus; Yang, Qin; Khanna, Kum Kum; Worman, Howard J.; Pandita, Tej K. Share Save Share Save Truncated Adenomatous Polyposis Coli Mutation Induces Asef-Activated Golgi FragmentationKim, Sang Bum; Zhang, Lu; Yoon, Jimok; Lee, Jeon; Min, Jaewon; Li, Wenlin; Grishin, Nick V.; Moon, Young-Ah; Wright, Woodring E.; Shay, Jerry W. Share Save Share Save 
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