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J

John E. Ladbury

University of Leeds

63H-index
379Paper Count
1.8WCitation Count
Published Papers 89
Publication Date
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SH3 domains selectively activate the PI3 kinase through non-conventional tertiary contacts
errCommunications Biology
IF5.1
err2026-01-19
err0
errOAAI
errSafia S. Aljedani; Anandsukeerthi Sandholu; Abdullah Aldehaiman; Siba Alharbi; Victor C. Y. Mak; Haiyan Wu; Panpan Wang; Afaque A. Momin; Upendra Singh; Adrien Lugari; Łukasz Jaremko; Mariusz Jaremko; Xavier Morelli; Jonathan W. Backer; John E. Ladbury; Michał Nowakowski; Lydia W. T. Cheung; Stefan T. Arold
errShare
errSave
Glycogen myophosphorylase loss causes increased dependence on glucose in iPSC-derived retinal pigment epithelium
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-08-01
err0
errOAAI
errBasu, Basudha; Karwatka, Magdalena; China, Becky; Mckibbin, Martin; Khan, Kamron; Inglehearn, Chris F.; Ladbury, John E.; Johnson, Colin A.
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errSave
Affinity purification mass spectrometry characterisation of the interactome of receptor tyrosine kinase proline-rich motifs in cancer
errHELIYON
IF3.6
err2024-08-01
err0
errOAAI
errJones, Christopher M.; Rohwedder, Arndt; Suen, Kin Man; Mohajerani, Safoura Zahed; Calabrese, Antonio N.; Knipp, Sabine; Bedford, Mark T.; Ladbury, John E.
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errSave
E7-mediated repression of miR-203 promotes LASP1-dependent proliferation in HPV-positive cervical cancer
errONCOGENE
IF7.3
err2024-05-24
err0
errOAAI
errPatterson, Molly R.; Meijers, Aniek S.; Ryder, Emma L.; Wootton, Louisa M.; Scarth, James A.; Evans, Debra; Turner, Amy L.; Wasson, Christopher W.; Darell, Janne E.; Theobald, Daisy A.; Cogan, Joseph A.; James, Claire D.; Wang, Miao; Ladbury, John E.; Morgan, Iain M.; Samson, Adel; Morgan, Ethan L.; Macdonald, Andrew
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errSave
The emerging role of receptor tyrosine kinase phase separation in cancer
errTRENDS IN CELL BIOLOGY
IF18.1
err2024-05-01
err7
errOAAI
errLin, Chi-Chuan; Suen, Kin Man; Lidster, Jessica; Ladbury, John E.
errShare
errSave
On-chip Raman spectroscopy of live single cells for the staging of oesophageal adenocarcinoma progression
errSCIENTIFIC REPORTS
IF3.9
err2024-01-19
err1
errOAAI
errFarooq, Alisha; Wood, Christopher D.; Ladbury, John E.; Evans, Stephen D.
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errSave
Expansion microscopy reveals subdomains in C. elegans germ granules (vol 6, e202201650, 2023)
errLIFE SCIENCE ALLIANCE
IF2.9
err2023-10-09
err0
errOAAI
errSuen, Kin M.; Sheard, Thomas M. D.; Lin, Chi-Chuan; Milonaityte, Dovile; Jayasinghe, Izzy; Ladbury, John E.
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errSave
The combined action of the intracellular regions regulates FGFR2 kinase activity
errCOMMUNICATIONS BIOLOGY
IF5.1
err2023-07-14
err3
errOAAI
errLin, Chi-Chuan; Wieteska, Lukasz; Poncet-Montange, Guillaume; Suen, Kin Man; Arold, Stefan T.; Ahmed, Zamal; Ladbury, John E.
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errSave
Regulation of microRNA expression by the adaptor protein GRB2
errSCIENTIFIC REPORTS
IF3.9
err2023-06-16
err3
errOAAI
errStainthorp, Amy K.; Lin, Chi-Chuan; Wang, Dapeng; Medhi, Ragini; Ahmed, Zamal; Suen, Kin Man; Miska, Eric A.; Whitehouse, Adrian; Ladbury, John E.
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errSave
PLBD: protein-ligand binding database of thermodynamic and kinetic intrinsic parameters
errDATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION
IF3.6
err2023-06-08
err9
errOAAI
errLinge, Darius; Gedgaudas, Marius; Merkys, Andrius; Petrauskas, Vytautas; Vaitkus, Antanas; Grybauskas, Algirdas; Paketuryte, Vaida; Zubriene, Asta; Zaksauskas, Audrius; Mickeviciute, Aurelija; Smirnoviene, Joana; Baranauskiene, Lina; Capkauskaite, Edita; Dudutiene, Virginija; Urniezius, Ernestas; Konovalovas, Aleksandras; Kazlauskas, Egidijus; Shubin, Kirill; Schioeth, Helgi B.; Chen, Wen-Yih; Ladbury, John E.; Grazulis, Saulius; Matulis, Daumantas
errShare
errSave
Phase separation enhances probability of receptor signalling and drug targeting
errTRENDS IN BIOCHEMICAL SCIENCES
IF11
err2023-05-01
err14
errOAAI
errLadbury, John E.; Lin, Chi-Chuan; Suen, Kin Man
errShare
errSave
Expansion microscopy reveals subdomains in C. elegans germ granules
errLIFE SCIENCE ALLIANCE
IF2.9
err2023-02-07
err2
errOAAI
errSuen, Kin M.; Sheard, Thomas M. D.; Lin, Chi-Chuan; Milonaityte, Dovile; Jayasinghe, Izzy; Ladbury, John E.
errShare
errSave
The Grb2 splice variant, Grb3-3, is a negative regulator of RAS activation
errCOMMUNICATIONS BIOLOGY
IF5.1
err2022-09-28
err7
errOAAI
errSeiler, Caroline; Stainthorp, Amy K.; Ketchen, Sophie; Jones, Christopher M.; Marks, Kate; Quirke, Philip; Ladbury, John E.
errShare
errSave
Receptor tyrosine kinases regulate signal transduction through a liquid-liquid phase separated state
errMOLECULAR CELL
IF16.6
err2022-03-01
err45
errOAAI
errLin, Chi-Chuan; Suen, Kin Man; Jeffrey, Polly-Anne; Wieteska, Lukasz; Lidster, Jessica A.; Bao, Peng; Curd, Alistair P.; Stainthorp, Amy; Seiler, Caroline; Koss, Hans; Miska, Eric; Ahmed, Zamal; Evans, Stephen D.; Molina-Paris, Carmen; Ladbury, John E.
errShare
errSave
Drug Resistance in Glioma Cells Induced by a Mesenchymal-Amoeboid Migratory Switch
errBIOMEDICINES
IF3.9
err2021-12-22
err9
errOAAI
errKetchen, Sophie E.; Gamboa-Esteves, Filomena O.; Lawler, Sean E.; Nowicki, Michal O.; Rohwedder, Arndt; Knipp, Sabine; Prior, Sally; Short, Susan C.; Ladbury, John E.; Bruening-Richardson, Anke
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errSave
Grb2 binding induces phosphorylation-independent activation of Shp2
errCOMMUNICATIONS BIOLOGY
IF5.1
err2021-04-01
err24
errOAAI
errLin, Chi-Chuan; Wieteska, Lukasz; Suen, Kin Man; Kalverda, Arnout P.; Ahmed, Zamal; Ladbury, John E.
errShare
errSave
Composition of receptor tyrosine kinase-mediated lipid micro-domains controlled by adaptor protein interaction
errSCIENTIFIC REPORTS
IF3.9
err2021-03-17
err9
errOAAI
errRohwedder, Arndt; Knipp, Sabine; Roberts, Lee D.; Ladbury, John E.
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errSave
DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans
errNATURE COMMUNICATIONS
IF15.7
err2020-08-25
err17
errOAAI
errSuen, Kin Man; Braukmann, Fabian; Butler, Richard; Bensaddek, Dalila; Akay, Alper; Lin, Chi-Chuan; Milonaityte, Dovile; Doshi, Neel; Sapetschnig, Alexandra; Lamond, Angus; Ladbury, John Edward; Miska, Eric Alexander
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errSave
A novel workflow for three-dimensional analysis of tumour cell migration
errINTERFACE FOCUS
IF4
err2020-02-14
err5
errOAAI
errKetchen, Sophie; Rohwedder, Arndt; Knipp, Sabine; Esteves, Filomena; Struve, Nina; Peckham, Michelle; Ladbury, John E.; Curd, Alistair; Short, Susan C.; Bruning-Richardson, Anke
errShare
errSave
Targeting the Shc-EGFR interaction with indomethacin inhibits MAP kinase pathway signalling
errCANCER LETTERS
IF10.1
err2019-08-01
err14
errOAAI
errLin, Chi-Chuan; Suen, Kin Man; Stainthorp, Amy; Wieteska, Lukasz; Biggs, George S.; Leitao, Andrei; Montanari, Carlos A.; Ladbury, John E.
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errSave

Research Directions

No research directions
Co-authors
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Anil K. Sood
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M
Mien‐Chie Hung
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G
George F. Gao
H-index: 135 · Papers: 1.2K
D
David I. Stuart
H-index: 129 · Papers: 1.1K
R
Robert L. Modlin
H-index: 127 · Papers: 511
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