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Adriano Aguzzi

university of zurich

123H-index
881Paper Count
6.1WCitation Count
Published Papers 291
Publication Date
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Prime editing of the β1 adrenoceptor in the brain restores physiological REM sleep in a mouse model of Alzheimer’s disease
errNature Communications
IF15.7
err2025-12-09
err0
errOAAI
errDesirée Böck; Lisa Tidecks; Maria Wilhelm; Waleed ElGrawani; Sian Duss; Chiara Trevisan; Dalila Vena; Anna Maria Reuss; Lucas Kissling; Matteo Ranucci; Mattia Privitera; Lisa K. Polzer; Athena E. Economides; Eleonora I. Ioannidi; Raquel Mendes; Yanik Weber; Justine Leonardi; Jonas Mumenthaler; Elina Villiger; Romain Goutagny; Chantal Mathis; Lukas Schmidheini; Tanja Rothgangl; Sharan Janjuha; Tommaso Patriarchi; Johannes Bohacek; Yaroslav Sych; Adriano Aguzzi; Jochen Winterer; Konstantinos Kompotis; Gerald Schwank
errShare
errSave
Large-scale seroepidemiology uncovers nephro-urological pathologies in people with tau autoimmunity
errPLOS BIOLOGY
IF7.2
err2025-11-26
err0
PREAI
errMagalhaes, Andreia D.; Emmenegger, Marc; De Cecco, Elena; Carta, Manfredi; Frontzek, Karl; Chincisan, Andra; Guo, Jingjing; Hornemann, Simone; Aguzzi, Adriano
errShare
errSave
Mutual reinforcement of lymphotoxin-driven myositis and impaired autophagy in murine muscle
errBRAIN
IF11.7
err2025-11-01
err0
errOAAI
errBremer, Juliane; Nagel, Judith; Zschuntzsch, Jana; Zajt, Kamil K.; Palaz, Tayfun; Blank, Thomas; Ikis, Aylin; Fischer, Laura A.; Sensmeyer, Anna S. M.; Wiechers, Lara; Reichelt, Josef J.; Hofmann, Kai P.; Wolf, Monika J.; Leuchtenberger, Corinna; Tripathi, Priyanka; Einer, Claudia; Zischka, Hans; Rothermel, Ulrike; Eck, Anna-L; Reimann, Regina R.; Kana, Veronika; Rushing, Elisabeth; Aguzzi, Adriano; Prinz, Marco; Liebetanz, David; Odoardi, Francesca; Kuo, Chao-Chung; Weis, Joachim; Kraft, Florian; Schmidt, Jens; Heikenwalder, Mathias
errShare
errSave
Ablation of progranulin augments microglial activation and accelerates prion progression
errActa Neuropathologica Communications
IF5.7
err2025-10-14
err0
errOAAI
errBei Li; Yiyue Shi; Wenyu Hou; Haoyuan Guan; Jun Li; Tuo Yi; Wei Li; Donglin Cai; Petra Schwarz; Adriano Aguzzi; Caihong Zhu
errShare
errSave
A Lymphotoxin-Driven Pathway to Hepatocellular Carcinoma
errCancer Cell
IF44.5
err2025-09-28
err0
PREAI
errJohannes Haybaeck; Nicolas Zeller; Monika Julia Wolf; Achim Weber; Ulrich Wagner; Michael Odo Kurrer; Juliane Bremer; Giandomenica Iezzi; Rolf Graf; Pierre-Alain Clavien; Robert Thimme; Hubert Blum; Sergei A. Nedospasov; Kurt Zatloukal; Muhammad Ramzan; Sandra Ciesek; Thomas Pietschmann; Patrice N. Marche; Michael Karin; Manfred Kopf; Jeffrey L. Browning; Adriano Aguzzi; Mathias Heikenwalder
errShare
errSave
Accelerating biomedical discoveries in brain health through transformative neuropathology of aging and neurodegeneration
errNeuron
IF15
err2025-07-18
err0
errOAAI
errMelissa E. Murray; Colin Smith; Vilas Menon; C. Dirk Keene; Ed Lein; Michael Hawrylycz; Adriano Aguzzi; Brett Benedetti; Katja Brose; Kelsey Caetano-Anolles; Maria Inmaculada Cobos Sillero; John F. Crary; Philip L. De Jager; Arline Faustin; Margaret E. Flanagan; Ozgun Gokce; Seth G.N. Grant; Lea T. Grinberg; David A. Gutman; Elizabeth M.C. Hillman; Zhi Huang; David J. Irwin; David T. Jones; Alifiya Kapasi; Celeste M. Karch; Walter T. Kukull; Tammaryn Lashley; Edward B. Lee; Thomas Lehner; Laura Parkkinen; Maria Pedersen; Dominique Pritchett; Matthew H. Rutledge; Julie A. Schneider; William W. Seeley; Claire E. Shepherd; Tara L. Spires-Jones; Judith A. Steen; Margaret Sutherland; Sanja Vickovic; Bin Zhang; David J. Stewart; Michael J. Keiser; Jacob W. Vogel; Brittany N. Dugger; Hemali Phatnani
errShare
errSave
Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention
errCancer Cell
IF44.5
err2025-07-03
err0
PREAI
errTracy O’Connor; Xiaolan Zhou; Jan Kosla; Arlind Adili; Maria Garcia Beccaria; Elena Kotsiliti; Dominik Pfister; Anna-Lena Johlke; Ankit Sinha; Roman Sankowski; Markus Schick; Richard Lewis; Nikolaos Dokalis; Bastian Seubert; Bastian Höchst; Donato Inverso; Danijela Heide; Wenlong Zhang; Petra Weihrich; Katrin Manske; Dirk Wohlleber; Martina Anton; Alexander Hoellein; Gitta Seleznik; Juliane Bremer; Sabine Bleul; Hellmut G. Augustin; Florian Scherer; Uwe Koedel; Achim Weber; Ulrike Protzer; Reinhold Förster; Thomas Wirth; Adriano Aguzzi; Felix Meissner; Marco Prinz; Bernd Baumann; Uta E. Höpken; Percy A. Knolle; Louisa von Baumgarten; Ulrich Keller; Mathias Heikenwalder
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errSave
Sheep with Scrapie and Mastitis Transmit Infectious Prions through the Milk (vol 85, pg 1136, 2011)
errJOURNAL OF VIROLOGY
IF3.8
err2025-06-17
err0
errOAAI
errLigios, Ciriaco; Cancedda, Maria Giovanna; Carta, Antonello; Santucciu, Cinzia; Maestrale, Caterina; Demontis, Francesca; Saba, Mariangela; Patta, Cristiana; DeMartini, James C.; Aguzzi, Adriano; Sigurdson, Christina J.
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errSave
Endothelial CCR2 Signaling Induced by Colon Carcinoma Cells Enables Extravasation via the JAK2-Stat5 and p38MAPK Pathway (vol 22, pg 91, 2012)
errCANCER CELL
IF44.5
err2025-05-01
err0
PREAI
errWolf, Monika Julia; Hoos, Alexandra; Bauer, Judith; Boettcher, Steffen; Knust, Markus; Weber, Achim; Simonavicius, Nicole; Schneider, Christoph; Lang, Matthias; Stuerzl, Michael; Croner, Roland S.; Konrad, Andreas; Manz, Markus G.; Moch, Holger; Aguzzi, Adriano; van Loo, Geert; Pasparakis, Manolis; Prinz, Marco; Borsig, Lubor; Heikenwalder, Mathias
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errSave
Triggering receptor expressed on myeloid cells-2 is involved in prion-induced microglial activation but does not contribute to prion pathogenesis in mouse brains (vol 36, pg 1994, 2015)
errNEUROBIOLOGY OF AGING
IF3.5
err2025-02-01
err0
PREAI
errZhu, Caihong; Herrmann, Uli S.; Li, Bei; Abakumova, Irina; Moos, Rita; Schwarz, Petra; Rushing, Elisabeth J.; Colonna, Marco; Aguzzi, Adriano
errShare
errSave
A genome-wide CRISPR activation screen to identify beta glucocerebrosidase modifiers
errMOLECULAR GENETICS AND METABOLISM
IF3.5
err2025-02-01
err0
PREAI
errRytel, Krystyna N.; Chen, Yu; Yin, Jiang; Aguzzi, Adriano; Sidransky, Ellen
errShare
errSave
Multiomic analyses direct hypotheses for Creutzfeldt-Jakob disease risk genes
errBrain
IF11.7
err2025-01-27
err0
errOAAI
errFahri Küçükali; Elizabeth Hill; Tijs Watzeels; Holger Hummerich; Tracy Campbell; Lee Darwent; Steven Collins; Christiane Stehmann; Gabor G Kovacs; Michael D Geschwind; Karl Frontzek; Herbert Budka; Ellen Gelpi; Adriano Aguzzi; Sven J van der Lee; Cornelia M van Duijn; Pawel P Liberski; Miguel Calero; Pascual Sanchez-Juan; Elodie Bouaziz-Amar; Jean-Louis Laplanche; Stéphane Haïk; Jean-Phillipe Brandel; Angela Mammana; Sabina Capellari; Anna Poleggi; Anna Ladogana; Dorina Tiple; Saima Zafar; Stephanie Booth; Gerard H Jansen; Aušrinė Areškevičiūtė; Eva Løbner Lund; Katie Glisic; Piero Parchi; Peter Hermann; Inga Zerr; Jiri Safar; Pierluigi Gambetti; Brian S Appleby; John Collinge; Kristel Sleegers; Simon Mead
errShare
errSave
Arrayed CRISPR libraries for the genome-wide activation, deletion and silencing of human protein-coding genes
errNATURE BIOMEDICAL ENGINEERING
IF26.6
err2024-12-04
err0
errOAAI
errYin, Jiang-An; Frick, Lukas; Scheidmann, Manuel C.; Liu, Tingting; Trevisan, Chiara; Dhingra, Ashutosh; Spinelli, Anna; Wu, Yancheng; Yao, Longping; Vena, Dalila Laura; Knapp, Britta; Guo, Jingjing; De Cecco, Elena; Ging, Kathi; Armani, Andrea; Oakeley, Edward J.; Nigsch, Florian; Jenzer, Joel; Haegele, Jasmin; Pikusa, Michal; Taeger, Joachim; Rodriguez-Nieto, Salvador; Bouris, Vangelis; Ribeiro, Rafaela; Baroni, Federico; Bedi, Manmeet Sakshi; Berry, Scott; Losa, Marco; Hornemann, Simone; Kampmann, Martin; Pelkmans, Lucas; Hoepfner, Dominic; Heutink, Peter; Aguzzi, Adriano
errShare
errSave
Direct and indirect regulation of β-glucocerebrosidase by the transcription factors USF2 and ONECUT2
errNPJ PARKINSONS DISEASE
IF8.2
err2024-10-22
err0
errOAAI
errGing, Kathi; Frick, Lukas; Schlachetzki, Johannes; Armani, Andrea; Zhu, Yanping; Gilormini, Pierre-Andre; Dhingra, Ashutosh; Boeck, Desiree; Marques, Ana; Deen, Matthew; Chen, Xi; Serdiuk, Tetiana; Trevisan, Chiara; Sellitto, Stefano; Pisano, Claudio; Glass, Christopher K.; Heutink, Peter; Yin, Jiang-An; Vocadlo, David J.; Aguzzi, Adriano
errShare
errSave
The cellular prion protein does not affect tau seeding and spreading of sarkosyl-insoluble fractions from Alzheimer's disease
errSCIENTIFIC REPORTS
IF3.9
err2024-09-16
err0
errOAAI
errSala-Jarque, Julia; Gil, Vanessa; Andres-Benito, Pol; Martinez-Soria, Ines; Picon-Pages, Pol; Hernandez, Felix; Avila, Jesus; Luis Lanciego, Jose; Nuvolone, Mario; Aguzzi, Adriano; Gavin, Rosalina; Ferrer, Isidro; Antonio del Rio, Jose
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errSave
α-Synuclein strain propagation is independent of cellular prion protein expression in a transgenic synucleinopathy mouse model
errPLOS PATHOGENS
IF4.9
err2024-09-12
err0
errOAAI
errSo, Raphaella W. L.; Amano, Genki; Stuart, Erica; Amini, Aeen Ebrahim; Aguzzi, Adriano; Collingridge, Graham L.; Watts, Joel C.
errShare
errSave
Prion diseases disrupt glutamate/glutamine metabolism in skeletal muscle
errPLOS PATHOGENS
IF4.9
err2024-09-11
err1
errOAAI
errCaredio, Davide; Koderman, Marusa; Frontzek, Karl J.; Sorce, Silvia; Nuvolone, Mario; Bremer, Juliane; Mariutti, Giovanni; Schwarz, Petra; Madrigal, Lidia; Mitrovic, Marija; Sellitto, Stefano; Streichenberger, Nathalie; Scheckel, Claudia; Aguzzi, Adriano
errShare
errSave
The ASC inflammasome adapter governs SAA-derived protein aggregation in inflammatory amyloidosis
errEMBO MOLECULAR MEDICINE
IF8.3
err2024-07-30
err2
errOAAI
errLosa, Marco; Emmenegger, Marc; De Rossi, Pierre; Schuerch, Patrick M.; Serdiuk, Tetiana; Pengo, Niccolo; Capron, Danaelle; Bieli, Dimitri; Bargenda, Niklas; Rupp, Niels J.; Carta, Manfredi C.; Frontzek, Karl J.; Lysenko, Veronika; Reimann, Regina R.; Schwarz, Petra; Nuvolone, Mario; Westermark, Gunilla T.; Nilsson, K. Peter R.; Polymenidou, Magdalini; Theocharides, Alexandre P. A.; Hornemann, Simone; Picotti, Paola; Aguzzi, Adriano
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errSave
Longitudinal microbiome investigation throughout prion disease course reveals pre- and symptomatic compositional perturbations linked to short-chain fatty acid metabolism and cognitive impairment in mice
errFRONTIERS IN MICROBIOLOGY
IF4.5
err2024-06-11
err0
errOAAI
errLosa, Marco; Morsy, Yasser; Emmenegger, Marc; Manz, Salomon M.; Schwarz, Petra; Aguzzi, Adriano; Scharl, Michael
errShare
errSave
Leptomeningeal collaterals regulate reperfusion in ischemic stroke and rescue the brain from futile recanalization
errNEURON
IF15
err2024-05-01
err10
errOAAI
errBinder, Nadine Felizitas; El Amki, Mohamad; Gluck, Chaim; Middleham, William; Reuss, Anna Maria; Bertolo, Adrien; Thurner, Patrick; Deffieux, Thomas; Lambride, Chryso; Epp, Robert; Handelsmann, Hannah-Lea; Baumgartner, Philipp; Orset, Cyrille; Bethge, Philipp; Kulcsar, Zsolt; Aguzzi, Adriano; Tanter, Mickael; Schmid, Franca; Vivien, Denis; Wyss, Matthias Tasso; Luft, Andreas; Weller, Michael; Weber, Bruno; Wegener, Susanne
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
J
John Q. Trojanowski
H-index: 255 · Papers: 1.8K
M
Michael Karin
H-index: 254 · Papers: 902
C
Cornelia M. van Duijn
H-index: 238 · Papers: 1.9K
D
Dennis W. Dickson
H-index: 218 · Papers: 2.3K
J
John Hardy
H-index: 207 · Papers: 1.9K
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