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TUMOR-WIDE RNA SPLICING ABERRATIONS GENERATE IMMUNOGENIC PUBLIC NEOANTIGENS IN GLIOBLASTOMAS AND OTHER CANCER TYPES Kwok, Darwin; Stevers, Nicholas; Etxeberria, Inaki; Nejo, Takahide; Cove, Maggie Colton; Chen, Lee; Jung, Jangham; Okada, Kaori; Lakshmanachetty, Senthilnath; Gallus, Marco; Barpanda, Abhilash; Hong, Chibo; Chan, Gary; Liu, Jerry; Wu, Samuel; Ramos, Emilio; Yamamichi, Akane; Watchmaker, Payal; Ogino, Hirokazu; Saijo, Atsuro; Du, Aidan; Grishanina, Nadia; Woo, James; Diaz, Aaron; Chang, Susan; Phillips, Joanna; Wiita, Arun; Klebanoff, Christopher; Costello, Joseph; Okada, Hideho Share Save
Dual-Vector-Transduction with Single-Step Magnetic Selection (Zip-sort) Increases Transgenic Payloads to Enhance CAR T Cell Activity James, Scott E.; Chen, Sophia; Ng, Brandon; Fischman, Jacob; Jahn, Lorenz; Boardman, Alexander P.; Rajagopalan, Adhithi; Elias, Harold K.; Massa, Alyssa R.; Manuele, Dylan; Nichols, Katherine; Lazrak, Amina; Lee, Nicole; Doto, Aoife; Mcmarland, Alexander; Petrichenko, Angelina; Everett, John; Bushman, Frederic; Fei, Teng; Kousa, Anastasia; Lemarquis, Andri Leo L.; Dewolf, Susan; Peled, Jonathan U.; Uardhana, Santosha A.; Klebanoff, Christopher A.; van den Brink, Marcel R. M. Share Save
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Defining and therapeutically targeting a fusion-derived public neoantigen in desmoplastic small round cell tumor using T cell receptor gene therapy Banks, Lauren; Arkin, Hannah; Chandran, Smita; Slotkin, Emily; Espinosa-Cotton, Madelyn; Shukla, Neerav; Morris, Luc; Ladanyi, Marc; Kung, Andrew; Klatt, Martin; Klebanoff, Christopher Share Save
AFNT-212: A TRAC-knocked-in KRASG12D-specific TCR-T cell product enhanced with CD8αß and a chimeric cytokine receptor for treatment of solid cancers Drain, Allison; Rouillard, Nicholas; Swanson, Nathaniel; Canestraro, Martina; Narayan, Santosh; Warner, Tyler; Danek, Nicole; Gareau, Ken; Liang, Jinsheng; Shen, Luhua; Tetrault, Tanya; Priyata, Iqraa; Vidyasagar, Sarah; Riggins-Walker, Taylor; Liu, Hui-Wen; Pechhold, Klaus; Brown, Lauren; Francis, Joshua; He, Xingyue; Browne, Patrick; Lamothe, Rebecca; Storlie, Meghan; Cost, Gregory; Schmitt, Thomas M.; Greenberg, Philip D.; Chandran, Smita S.; Klebanoff, Christopher A.; Lam, Hubert; Gupta, Ankit; Hallet, Damien; Shapiro, Gary; Nguyen, Kim; Vincent, Loic Share Save
HLA genotyping and HLA-based clinical trial matching using MSK-IMPACT, a targeted next-generation sequencing assay Chen, Monica F.; Gormally, Michael V.; Noronha, Anne Marie; Panageas, Kristalla; Reynolds, Maggie; Kohlasch, Kaelyn; Novak, Bryan; Kee-Velez, Tatiana; Clarke, Nikeysha; Kyi, Chrisann; Friedman, Claire; D'Angelo, Sandra; Kris, Mark G.; Klebanoff, Christopher A.; Shah, Ronak; Berger, Michael; Bandlamudi, Chaitanya; Drilon, Alexander; Donoghue, Mark T. Share Save
Persistence but not antitumor efficacy of CAR-engineered lymphocytes is governed by a FAS/FAS ligand auto-regulatory circuit Yi, Fei; Cohen, Tal; Zumbo, Paul; Eltilib, Razan; Arkin, Hannah; Gormally, Michael; Hackett, Christopher S.; Kropp, Korbinian; Chandran, Smita; Park, Jae H.; Betel, Doron; Klebanoff, Christopher A. Share Save
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Novel public and tumor-wide neoantigens arising from clonal aberrant splicing events drive tumor-specific T-cell responses across diverse cancer types Kwok, Darwin; Stevers, Nicholas O.; Nejo, Takahide; Chen, Lee H.; Etxeberria, Inaki; Jung, Jangham; Okada, Kaori; Cove, Maggie Colton; Lakshmanachetty, Senthilnath; Gallus, Marco; Barpanda, Abhilash; Hong, Chibo; Chan, Gary Kl; Wu, Samuel H.; Ramos, Emilio; Yamamichi, Akane; Liu, Jerry Yz; Watchmaker, Payal; Ogino, Hirokazu; Saijo, Atsuro; Du, Aidan; Grishanina, Nadia; Woo, James; Diaz, Aaron; Chang, Susan M.; Phillips, Joanna J.; Wiita, Arun P.; Klebanoff, Christopher A.; Costello, Joseph F.; Okada, Hideho Share Save
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Nivolumab plus ipilimumab in advanced salivary gland cancer: a phase 2 trial Vos, Joris L.; Burman, Bharat; Jain, Swati; Fitzgerald, Conall W. R.; Sherman, Eric J.; Dunn, Lara A.; Fetten, James V.; Michel, Loren S.; Kriplani, Anuja; Ng, Kenneth K.; Eng, Juliana; Tchekmedyian, Vatche; Haque, Sofia; Katabi, Nora; Kuo, Fengshen; Han, Catherine Y.; Nadeem, Zaineb; Yang, Wei; Makarov, Vladimir; Srivastava, Raghvendra M.; Ostrovnaya, Irina; Prasad, Manu; Zuur, Charlotte L.; Riaz, Nadeem; Pfister, David G.; Klebanoff, Christopher A.; Chan, Timothy A.; Ho, Alan L.; Morris, Luc G. T. Share Save
Perspectives in Immunotherapy: meeting report from Immunotherapy Bridge (Naples, November 30th-December 1st, 2022) Ascierto, Paolo A.; Avallone, Antonio; Bifulco, Carlo; Bracarda, Sergio; Brody, Joshua D.; Emens, Leisha A.; Ferris, Robert L.; Formenti, Silvia C.; Hamid, Omid; Johnson, Douglas B.; Kirchhoff, Tomas; Klebanoff, Christopher A.; Lesinski, Gregory B.; Monette, Anne; Neyns, Bart; Odunsi, Kunle; Paulos, Chrystal M.; Powell Jr, Daniel J.; Rezvani, Katayoun; Segal, Brahm H.; Singh, Nathan; Sullivan, Ryan J.; Fox, Bernard A.; Puzanov, Igor Share Save
The ectonucleotidase CD39 identifies tumor-reactive CD8+T cells predictive of immune checkpoint blockade efficacy in human lung cancer Chow, Andrew; Uddin, Fathema Z.; Liu, Michael; Dobrin, Anton; Nabet, Barzin Y.; Mangarin, Levi; Lavin, Yonit; Rizvi, Hira; Tischfield, Sam E.; Quintanal-Villalonga, Alvaro; Chan, Joseph M.; Shah, Nisargbhai; Allaj, Viola; Manoj, Parvathy; Mattar, Marissa; Meneses, Maximiliano; Landau, Rebecca; Ward, Mariana; Kulick, Amanda; Kwong, Charlene; Wierzbicki, Matthew; Yavner, Jessica; Egger, Jacklynn; Chavan, Shweta S.; Farillas, Abigail; Holland, Aliya; Sridhar, Harsha; Ciampricotti, Metamia; Hirschhorn, Daniel; Guan, Xiangnan; Richards, Allison L.; Heller, Glenn; Mansilla-Soto, Jorge; Sadelain, Michel; Klebanoff, Christopher A.; Hellmann, Matthew D.; Sen, Triparna; de Stanchina, Elisa; Wolchok, Jedd D.; Merghoub, Taha; Rudin, Charles M. Share Save
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Perspectives in Immunotherapy: meeting report from the Immunotherapy Bridge, December 1st-2nd, 2021 Ascierto, Paolo A.; Avallone, Antonio; Bhardwaj, Nina; Bifulco, Carlo; Bracarda, Sergio; Brody, Joshua D.; Buonaguro, Luigi; Demaria, Sandra; Emens, Leisha A.; Ferris, Robert L.; Galon, Jerome; Khleif, Samir N.; Klebanoff, Christopher A.; Laskowski, Tamara; Melero, Ignacio; Paulos, Chrystal M.; Pignata, Sandro; Ruella, Marco; Svane, Inge Marie; Taube, Janis M.; Fox, Bernard A.; Hwu, Patrick; Puzanov, Igor Share Save
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