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SaveA Common CTRB misfolding variant associated with pancreatic cancer risk causes ER stress and inflammation in mice
Bodas, Cristina; Felipe, Irene; Chanez, Brice; Lafarga, Miguel; Lopez de Maturana, Evangelina; Martinez de Villarreal, Jaime; del Pozo, Natalia; Malumbres, Marina; Vargiu, Pierfrancesco; Cayuela, Ana; Peset, Isabel; Connelly, Katelyn; Hoskins, Jason; Mendez, Raul; Amundadottir, Laufey; Malats, Nuria; Ortega, Sagrario; Real, Francisco X. Share Save CPEB4 modulates liver cancer progression by translationally regulating hepcidin expression and sensitivity to ferroptosisDelgado, M. Eugenia; Naranjo-Suarez, Salvador; Ramirez-Pedraza, Marta; Cardenas, Beatriz I.; Gallardo-Martinez, Carmen; Balvey, Alexandra; Belloc, Eulalia; Martin, Judit; Boyle, Mark; Mendez, Raul; Fernandez, Mercedes Share Save CPEB4-CLOCK crosstalk during temporal lobe epilepsyde Diego-Garcia, Laura; Brennan, Gary P.; Auer, Theresa; Menendez-Mendez, Aida; Parras, Alberto; Martin-Gil, Alba; Mitra, Meghma; Olla, Ivana; Villalba-Benito, Leticia; Gil, Beatriz; Alves, Mariana; Lau, Kelvin; Delanty, Norman; Beausang, Alan; Cryan, Jane; Brett, Francesca M.; Farrell, Michael A.; O'Brien, Donncha F.; Mendez, Raul; Carracedo-Rodriguez, Gonzalo; Henshall, David C. C.; Lucas, Jose J.; Engel, Tobias Share Save NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiationCobo, Isidoro; Paliwal, Sumit; Bodas, Cristina; Felipe, Irene; Melia-Aloma, Julia; Torres, Ariadna; Martinez-Villarreal, Jaime; Malumbres, Marina; Garcia, Fernando; Millan, Irene; del Pozo, Natalia; Park, Joo-Cheol; MacDonald, Ray J.; Munoz, Javier; Mendez, Raul; Real, Francisco X. Share Save Share Save Share Save Share Save Antitumor T-cell function requires CPEB4-mediated adaptation to chronic endoplasmic reticulum stressFernandez-Alfara, Marcos; Sibilio, Annarita; Martin, Judit; Tusquets Uxo, Elsa; Malumbres, Marina; Alcalde, Victor; Chanes, Veronica; Canellas-Socias, Adria; Palomo-Ponce, Sergio; Batlle, Eduard; Mendez, Raul Share Save Comparative analyses of vertebrate CPEB proteins define two subfamilies with coordinated yet distinct functions in post-transcriptional gene regulationDuran-Arque, Berta; Canete, Manuel; Lara Castellazzi, Chiara; Bartomeu, Anna; Ferrer-Caelles, Anna; Reina, Oscar; Caballe, Adria; Gay, Marina; Arauz-Garofalo, Gianluca; Belloc, Eulalia; Mendez, Raul Share Save Macrophage inflammation resolution requires CPEB4-directed offsetting of mRNA degradationSuner, Clara; Sibilio, Annarita; Martin, Judit; Castellazzi, Chiara Lara; Reina, Oscar; Dotu, Ivan; Caballe, Adria; Rivas, Elisa; Calderone, Vittorio; Diez, Juana; Nebreda, Angel R.; Mendez, Raul Share Save Targeting the cytoplasmic polyadenylation element-binding protein CPEB4 protects against diet-induced obesity and microbiome dysbiosisPell, Nuria; Garcia-Pras, Ester; Gallego, Javier; Naranjo-Suarez, Salvador; Balvey, Alexandra; Suner, Clara; Fernandez-Alfara, Marcos; Chanes, Veronica; Carbo, Julia; Ramirez-Pedraza, Marta; Reina, Oscar; Thingholm, Louise; Bang, Corinna; Ruhlemann, Malte; Franke, Andre; Schierwagen, Robert; Rheinwalt, Karl P.; Trebicka, Jonel; Mendez, Raul; Fernandez, Mercedes Share Save CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable SLC19A3 deficiency in Huntington's diseasePico, Sara; Parras, Alberto; Santos-Galindo, Maria; Pose-Utrilla, Julia; Castro, Margarita; Fraga, Enrique; Hernandez, Ivo H.; Elorza, Ainara; Anta, Hector; Wang, Nan; Marti-Sanchez, Laura; Belloc, Eulalia; Garcia-Esparcia, Paula; Garrido, Juan J.; Ferrer, Isidro; Macias-Garcia, Daniel; Mir, Pablo; Artuch, Rafael; Perez, Belen; Hernandez, Felix; Navarro, Pilar; Luis Lopez-Sendon, Jose; Iglesias, Teresa; Yang, X. William; Mendez, Raul; Lucas, Jose J. Share Save CPEB ALTERATION AND ABERRANT TRANSCRIPTOME-POLYADENYLATION UNVEIL A TREATABLE VITAMIN B1 DEFICIENCY IN HUNTINGTON'S DISEASEPico, Sara; Parras, Alberto; Santos-Galindo, Maria; Pose-Utrilla, Julia; Castro, Margarita; Fraga, Enrique; Hernandez, Ivo H.; Elorza, Ainara; Anta, Hector; Wang, Nan; Marti-Sanchez, Laura; Belloc, Eulalia; Garcia-Esparcia, Paula; Garrido, Juan J.; Ferrer, Isidro; Macias-Garcia, Daniel; Mir, Pablo; Artuch, Rafael; Perez, Belen; Hernandez, Felix; Navarro, Pilar; Lopez-Sendon, Jose Luis; Iglesias, Teresa; Yang, X. William; Mendez, Raul; Lucas, Jose J. Share Save Identification of dynamic RNA-binding proteins uncovers a Cpeb4-controlled regulatory cascade during pathological cell growth of cardiomyocytesRiechert, Eva; Kmietczyk, Vivien; Stein, Frank; Schwarzl, Thomas; Sekaran, Thileepan; Juergensen, Lonny; Kamuf-Schenk, Verena; Varma, Eshita; Hofmann, Christoph; Rettel, Mandy; Guer, Kira; Oelschlaeger, Julie; Kuehl, Friederike; Martin, Judit; Ramirez-Pedraza, Marta; Fernandez, Mercedes; Doroudgar, Shirin; Mendez, Raul; Katus, Hugo A.; Hentze, Matthias W.; Voelkers, Mirko Share Save mRNA spindle localization and mitotic translational regulation by CPEB1 and CPEB4Pascual, Rosa; Segura-Morales, Carolina; Omerzu, Manja; Bellora, Nicolas; Belloc, Eulalia; Lara Castellazzi, Chiara; Reina, Oscar; Eyras, Eduardo; Maurice, Madelon M.; Millanes-Romero, Alba; Mendez, Raul Share Save High concordance between hippocampal transcriptome of the mouse intra-amygdala kainic acid model and human temporal lobe epilepsyConte, Giorgia; Parras, Alberto; Alves, Mariana; Olla, Ivana; De Diego-Garcia, Laura; Beamer, Edward; Alalqam, Razi; Ocampo, Alejandro; Mendez, Raul; Henshall, David C.; Lucas, Jose J.; Engel, Tobias Share Save CPEB4 Increases Expression of PFKFB3 to Induce Glycolysis and Activate Mouse and Human Hepatic Stellate Cells, Promoting Liver FibrosisMejias, Marc; Gallego, Javier; Naranjo-Suarez, Salvador; Ramirez, Marta; Pell, Nuria; Manzano, Anna; Suner, Clara; Bartrons, Ramon; Mendez, Raul; Fernandez, Mercedes Share Save Polyadenylation of mRNA as a novel regulatory mechanism of gene expression in temporal lobe epilepsyParras, Alberto; De Diego-Garcia, Laura; Alves, Mariana; Beamer, Edward; Conte, Giorgia; Jimenez-Mateos, Eva M.; Morgan, James; Olla, Ivana; Hernandez-Santana, Yasmina; Delanty, Norman; Farrell, Michael A.; O'Brien, Donncha F.; Ocampo, Alejandro; Henshall, David C.; Mendez, Raul; Lucas, Jose J.; Engel, Tobias Share Save The RNA binding protein CPEB2 regulates hormone sensing in mammary gland development and luminal breast cancerPascual, Rosa; Martin, Judit; Salvador, Fernando; Reina, Oscar; Chanes, Veronica; Millanes-Romero, Alba; Suner, Clara; Fernandez-Miranda, Gonzalo; Bartomeu, Anna; Huang, Yi-Shuian; Gomis, Roger R.; Mendez, Raul Share Save 
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