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Phase I study of bevacizumab and temsirolimus combination therapy in advanced malignancies: safety, efficacy, and ovarian cancer expansion Piha-Paul, Sarina A.; Tseng, Chieh; Thompson, Emily; Stafford, R. Jason; Le, Hung; Kang, Lei; Fu, Siqing; Tsimberidou, Apostolia; Blumenschein, George; Ahnert, Jordi Rodon; Slopis, John M.; Hong, David; Naing, Aung; Meric-Bernstam, Funda; Ng, Chaan S.; Westin, Shannon; Sood, Anil K. Share Save
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Phase 1 study of zavondemstat (TACH101), a first-in-class KDM4 inhibitor, in patients with advanced solid tumors Tsimberidou, Apostolia M.; Dayyani, Farshid; Sommerhalder, David; Vandross, Andrae L.; Pelster, Meredith S.; Henry, Jason T.; Perez, Cesar A.; Chakraborty, Abhijit; Baysal, Mehmet A.; Chandhasin, Chandtip; Dai, Yiyun; Tu, Shirley; King, Ivan; Perabo, Frank Share Save
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Selinexor in combination with carboplatin and paclitaxel in patients with advanced solid tumors: results of a single-center, multi-arm phase Ib study (vol 40, pg 290, 2022) Thein, Kyaw Z.; Karp, Daniel D.; Tsimberidou, Apostolia; Gong, Jing; Sulovic, Selma; Shah, Jatin; Milton, Denai R.; Hong, David S.; Janku, Filip; Mcquinn, Lacey; Stephen, Bettzy A.; Colen, Rivka; Carter, Brett W.; Yap, Timothy A.; Piha-Paul, Sarina A.; Fu, Siqing; Meric-Bernstam, Funda; Naing, Aung Share Save
A phase 2 basket study of talabostat, a small-molecule inhibitor of dipeptidyl peptidases, administered in combination with pembrolizumab in patients with advanced solid cancers Ahmed, Jibran; Janku, Filip; Karp, Daniel D.; Piha-Paul, Sarina A.; Tsimberidou, Apostolia M.; Yap, Timothy Anthony; Stephen, Bettzy; Yang, Yali; Gurses, Serdar; Liu, Qian; Song, Juhee; Meric-Bernstam, Funda; Naing, Aung Share Save
Updated efficacy and safety of botensilimab plus balstilimab in patients with refractory metastatic sarcoma from an expanded phase I study Wilky, B. A.; Trent, J. C.; Tsimberidou, A. M.; Gordon, M.; El-Khoueiry, A. B.; Bullock, A.; Henick, B. S.; Agulnik, M.; Mahadevan, D.; Singh, A.; Wu, W.; Avagyan, M.; Patel, J. M.; Grossman, J.; O'Day, S. J.; Schwartz, G.; Jones, R. L. Share Save
Immunologic signatures of response and resistance to nivolumab with ipilimumab in advanced metastatic cancer Tsimberidou, Apostolia M.; Alayli, Farah A.; Okrah, Kwame; Drakaki, Alexandra; Khalil, Danny N.; Kummar, Shivaani; Khan, Saad A.; Hodi, F. Stephen; Oh, David Y.; Cabanski, Christopher R.; Gautam, Shikha; Meier, Stefanie L.; Amouzgar, Meelad; Pfeiffer, Shannon M.; Kageyama, Robin; Yang, Enjun; Spasic, Marko; Tetzlaff, Michael T.; Foo, Wai Chin; Hollmann, Travis J.; Li, Yanyun; Adamow, Matthew; Wong, Phillip; Moore, Jonni S.; Velichko, Sharlene; Chen, Richard O.; Kumar, Dinesh; Bucktrout, Samantha; Ibrahim, Ramy; Dugan, Ute; Salvador, Lisa; Hubbard-Lucey, Vanessa M.; O'Donnell-Tormey, Jill; Santulli-Marotto, Sandra; Butterfield, Lisa H.; Da Silva, Diane M.; Fairchild, Justin; Lavallee, Theresa M.; Padron, Lacey J.; Sharma, Padmanee Share Save
Phase II study of talazoparib in advanced cancers with BRCA1/2, DNA repair, and PTEN alterations Piha-Paul, Sarina A.; Tseng, Chieh; Leung, Cheuk Hong; Yuan, Ying; Karp, Daniel D.; Subbiah, Vivek; Hong, David; Fu, Siqing; Naing, Aung; Rodon, Jordi; Javle, Milind; Ajani, Jaffer A.; Raghav, Kanwal P.; Somaiah, Neeta; Mills, Gordon B.; Tsimberidou, Apostolia M.; Zheng, Xiaofeng; Chen, Ken; Meric-Bernstam, Funda Share Save
Botensilimab plus balstilimab in relapsed/refractory microsatellite stable metastatic colorectal cancer: a phase 1 trial Bullock, Andrea J.; Schlechter, Benjamin L.; Fakih, Marwan G.; Tsimberidou, Apostolia M.; Grossman, Joseph E.; Gordon, Michael S.; Wilky, Breelyn A.; Pimentel, Agustin; Mahadevan, Daruka; Balmanoukian, Ani S.; Sanborn, Rachel E.; Schwartz, Gary K.; Abou-Alfa, Ghassan K.; Segal, Neil H.; Bockorny, Bruno; Moser, Justin C.; Sharma, Sunil; Patel, Jaymin M.; Wu, Wei; Chand, Dhan; Rosenthal, Katherine; Mednick, Gabriel; Delepine, Chloe; Curiel, Tyler J.; Stebbing, Justin; Lenz, Heinz-Josef; O'Day, Steven J.; El-Khoueiry, Anthony B. Share Save
A phase I study of TAK-659 and paclitaxel in patients with taxane-refractory advanced solid tumors Gouda, M. A.; Shunyakova, J.; Naing, A.; Dumbrava, E.; Hong, D. S.; Yuan, Y.; Yang, P.; Myers, A.; Liang, Y.; Peng, J.; Karp, D.; Tsimberidou, A. M.; Rodon, J.; Yap, T. A.; Piha-Paul, S. A.; Meric-Bernstam, F.; Fu, S. Share Save
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The efficacy and safety of tinengotinib in patients with advanced or metastatic HR+/HER2-breast cancer or TNBC Sarina, Piha-Paul; Xu, Binghe; Fan, Ying; Yuan, Yuan; Lavasani, Sayeh; Mortimer, Joanne; Goel, Sanjay; Tsimberidou, Apostolia; Ibrahim, Nuhad; Abouharb, Sausan; Barcenas, Carlos; Lheme, Adaeze; Karp, Daniel; Ahnert, Jordi Rodon; Dumbrava, Ecaterina; Fan, Jean; Peng, Peng; Sun, Caixia; Wang, Hui; Hennessy, Katie; Fu, Ximei; Xu, Ruolan; Ni, Shumao; Wu, Frank; Meric-Bernstam, Funda Share Save
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NCI10217: Phase Ib biomarker-driven tumor-agnostic combination (Combo) trial of copanlisib (Copa) and olaparib (Ola) in molecularly-selected patients (pts) with advanced cancers with PIK3CA hotspot, PTEN and DNA damage response (DDR) mutations Yap, Timothy A.; Dumbrava, Ecaterina E.; Ahnert, Jordi Rodon; Tsimberidou, Apostolia M.; Hong, David; Piha-Paul, Sarina A.; Karp, Daniel D.; Fu, Siqing; Naing, Aung; Pohlmann, Paula; Rhudy, Jessica R.; Berenji-Jalaei, Sheila B.; Cole, Ashley A.; Valladolid, Christian; Dufner, Desirae; Bockorny, Bruno B.; Bullock, Andrea; Fein, Daniel; Buchbinder, Elizabeth; Choudhury, Atish; Haddox, Candace; Lee, Elizabeth; Wulf, Gerburg; Ivy, Percy; Said, Rabih; Shapiro, Geoffrey; Meric-Bernstam, Funda Share Save
Evaluating nivolumab (nivo) plus ipilimumab (ipi) in patients with metastatic castration-resistant prostate cancer (mCRPC): Clinical and translational results from the AMADEUS prostate expansion cohort Tsimberidou, Apostolia M.; Drakaki, Alexandra; Khalil, Danny N.; Okrah, Kwame; Schachter, Mike; Gautam, Shikha; Da Silva, Diane M.; Alayli, Farah A.; Spencer, Christine N.; Foo, Wai Chin; Adamow, Matthew; Wong, Phillip; Fairchild, Justin; Arnott, Jamie; Dugan, Ute; Boffo, Silvia; Salvador, Lisa; Cabanski, Christopher R.; Subudhi, Sumit K.; Sharma, Padmanee Share Save