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Association of statin use on survival outcomes of patients with early-stage HER2-positive breast cancer in the APHINITY trial Maurer, Christian; Agostinetto, Elisa; Ameye, Lieveke; Lambertini, Matteo; Martel, Samuel; Ponde, Noam; Brandao, Mariana; Poggio, Francesca; Ferreira, Arlindo; Schiff, Rachel; De Angelis, Carmine; Gelber, Richard D.; Dent, Susan; Thomssen, Christoph; Piccart, Martine; de Azambuja, Evandro Share Save
PKMYT1 Is a Marker of Treatment Response and a Therapeutic Target for CDK4/6 Inhibitor-Resistance in ER+ Breast Cancer Chen, Anran; Kim, Beom-Jun; Mitra, Aparna; Vollert, Craig T.; Lei, Jonathan T.; Fandino, Diana; Anurag, Meenakshi; Holt, Matthew V.; Gou, Xuxu; Pilcher, Jacob B.; Goetz, Matthew P.; Northfelt, Donald W.; Hilsenbeck, Susan G.; Marshall, C. Gary; Hyer, Marc L.; Papp, Robert; Yin, Shou-Yun; De Angelis, Carmine; Schiff, Rachel; Fuqua, Suzanne A. W.; Ma, Cynthia X.; Foulds, Charles E.; Ellis, Matthew J. Share Save
Mechanisms of Resistance to HER2-Targeted Therapies in HER2-positive Breast Cancer Veeraraghavan, Jamunarani; Liao, Fu-Tien; Qin, Lanfang; Gordon, Tia; Raghavan, Alekya; Sabotta, Caroline; Kaplan, Rachel; Gutierrez, Carolina; Osborne, C. Kent; Rimawi, Mothaffar F.; Schiff, Rachel Share Save
High FOXA1 levels induce ER transcriptional reprogramming, a pro-metastatic secretome, and metastasis in endocrine-resistant breast cancer Fu, Xiaoyong; Pereira, Resel; Liu, Chia -Chia; De Angelis, Carmine; Shea, Martin J.; Nanda, Sarmistha; Qin, Lanfang; Mitchell, Tamika; Cataldo, Maria L.; Veeraraghavan, Jamunarani; Sethunath, Vidyalakshmi; Giuliano, Mario; Gutierrez, Carolina; Gyorffy, Balazs; Trivedi, Meghana, V; Cohen, Ofir; Wagle, Nikhil; Nardone, Agostina; Jeselsohn, Rinath; Rimawi, Mothaffar F.; Osborne, C. Kent; Schiff, Rachel Share Save
Metastatic models of resistance to next generation tyrosine kinase inhibitors (TKIs) in HER2-positive breast cancer (BC) Liao, Fu-Tien; Qin, Lanfang; Shea, Martin J.; Bado, Igor; Wu, Yi-Hsuan; Wu, Ling; Gao, Yang; Nanda, Sarmistha; Gordon, Tia; Liu, Chia Chia; Zhang, Xiang H. -F.; Osborne, C. Kent; Rimawi, Mothaffar F.; Veeraraghavan, Jamunarani; Schiff, Rachel Share Save
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Super-enhancer-oriented integrative bioinformatics identifies aberrant KLF4 signaling in endocrine-resistant breast cancer (BC) Liu, Chia Chia; Qin, Lanfang; Sathe, Shanunak; Nanda, Sarmistha; Veeraraghavan, Jamunarani; Cohen, Ofir; Wagle, Nikhil; Rimawi, Mothaffar; Osborne, C. Kent; Fu, Xiaoyong; Schiff, Rachel Share Save
Hyperactivation of the EGFR pathway is associated with resistance to tucatinib in HER2-positive breast cancer models Liao, Fu-Tien; Gordon, Tia; Liu, Chia Chia; Selenica, Pier; Zhu, Yingjie; Patel, Juber; Nanda, Sarmistha; Qin, Lanfang; Fu, Xiaoyong; Gazzo, Andrea; Marra, Antonio; Blanco-Heredia, Juan; Weigelt, Britta; Reis-Filho, Jorge; Osborne, C. Kent; Rimawi, Mothaffar; Schiff, Rachel; Veeraraghavan, Jamunarani Share Save
A Distinct Chromatin State Drives Therapeutic Resistance in Invasive Lobular Breast Cancer Nardone, Agostina; Qiu, Xintao; Spisak, Sandor; Nagy, Zsuzsanna; Feiglin, Ariel; Feit, Avery; Feit, Gabriela Cohen; Xie, Yingtian; Font-Tello, Alba; Guarducci, Cristina; Hermida-Prado, Francisco; Syamala, Sudeepa; Lim, Klothilda; Gomez, Miguel Munoz; Pun, Matthew; Cornwell, MacIntosh; Liu, Weihan; Ors, Aysegul; Mohammed, Hisham; Cejas, Paloma; Brock, Jane B.; Freedman, Matthew L.; Winer, Eric P.; Fu, Xiaoyong; Schiff, Rachel; Long, Henry W.; Filho, Otto Metzger; Jeselsohn, Rinath Share Save
Impact of statin use on survival outcomes of patients with HER2-positive early breast cancer in the APHINITY trial Maurer, C.; Agostinetto, E.; Ameye, L.; Lambertini, M.; Martel, S.; Ponde, N. F.; Brandao, M.; Poggio, F.; Ferreira, A. R.; Schiff, R.; De Angelis, C.; Gelber, R. D.; Dent, S.; Thomssen, C.; Piccart, M.; de Azambuja, E. Share Save
Acquired resistance to tucatinib is associated with EGFR amplification in HER2+breast cancer (BC) models and can be overcome by a more complete blockade of HER receptor layer Veeraraghavan, Jamunarani; Bose, Sreyashree; Mistry, Ragini; Selenica, Pier; Nanda, Sarmistha; Qin, Lanfang; Gazzo, Andrea; Zhu, Yingjie; Mancini, Michael A.; Stossi, Fabio; Weigelt, Britta; Reis-Filho, Jorge S.; Osborne, C. Kent; Rimawi, Mothaffar F.; Schiff, Rachel Share Save
Resistance to next generation tyrosine kinase inhibitors (TKIs) in HER2-positive breast cancer (BC): Role of HER and PIK3CA mutations and development of new treatment strategies and study models Bose, Sreyashree; Mistry, Ragini; Liu, Chia Chia; Nanda, Sarmistha; Qin, Lanfang; Selenica, Pier; Gazzo, Andrea; Zhu, Yingjie; Mancini, Michael A.; Stossi, Fabio; Diala, Irmina; Eli, Lisa D.; Weigelt, Britta; Reis-Filho, Jorge S.; Rimawi, Mothaffar F.; Osborne, C. Kent; Schiff, Rachel; Veeraraghavan, Jamunarani Share Save
Targeting the FRA1-dependent transcriptional nexus in high FOXA1-driven endocrine-resistant and metastatic breast cancer Liu, Chia Chia; Qin, Lanfang; De Angelis, Carmine; Nanda, Sarmistha; Pereira, Resel; Shea, Martin J.; Nardone, Agostina; Jeselsohn, Rinath; Cohen, Ofir; Wagle, Nikhil; Liu, Zhijie; Rimawi, Mothaffar F.; Osborne, C. Kent; Schiff, Rachel; Fu, Xiaoyong Share Save
NPY1R exerts inhibitory action on estradiol-stimulated growth and predicts endocrine sensitivity and better survival in ER-positive breast cancer Bhat, Raksha; Thangavel, Hariprasad; Abdulkareem, Noor Mazin; Vasaikar, Suhas; De Angelis, Carmine; Bae, Leon; Cataldo, Maria Letizia; Nanda, Sarmistha; Fu, Xiaoyong; Zhang, Bing; Schiff, Rachel; Trivedi, Meghana, V Share Save
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