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Comparative analysis of Bcl-2 family protein overexpression in CAR T cells alone and in combination with BH3 mimetics Korell, Felix; Olson, Michael L.; Salas-Benito, Diego; Leick, Mark B.; Larson, Rebecca C.; Bouffard, Amanda; Silva, Harrison; Gasparetto, Alessandro; Berger, Trisha R.; Kann, Michael C.; Mergen, Markus; Kienka, Tamina; Wehrli, Marc; Haradhvala, Nicholas J.; Bailey, Stefanie R.; Letai, Anthony; Maus, Marcela V. Share Save
Acquired Multidrug Resistance in AML Is Caused by Low Apoptotic Priming in Relapsed Myeloblasts Olesinski, Elyse A.; Bhatia, Karanpreet Singh; Wang, Chuqi; Pioso, Marissa S.; Lin, Xiao Xian; Mamdouh, Ahmed M.; Ng, Shu Xuan; Sandhu, Vedant; Jasdanwala, Shaista Shabbir; Yilma, Binyam; Bohl, Stephan; Ryan, Jeremy A.; Malani, Disha; Luskin, Marlise R.; Kallioniemi, Olli; Porkka, Kimmo; Adamia, Sophia; Chng, Wee Joo; Osato, Motomi; Weinstock, David M.; Garcia, Jacqueline S.; Letai, Anthony; Bhatt, Shruti Share Save
Targeting casein kinase 1 alpha (CK1 alpha) and transcriptional CDKs (CDK7/9) in human liposarcomas Liu, Renyan; Solimini, Nicole L.; Bhola, Patrick; Branigan, Timothy B.; Hao, Jie; Wang, Xin; Alharthi, Roshen; Yorsz, Michael; Soni, Shaili; Hu, Cing-siang; Snir-Alkalay, Irit; Gokhale, Prafulla; Letai, Anthony; Ben-Neriah, Yinon Yinon; Demetri, George D.; Shapiro, Geoffrey I. Share Save
Prophylactic maintenance with venetoclax/azacitidine after reduced-intensity conditioning allogeneic transplant for high-risk MDS and AML Garcia, Jacqueline S.; Kim, Haesook T.; Murdock, H. Moses; Ansuinelli, Michela; Brock, Jennifer; Cutler, Corey S.; Gooptu, Mahasweta; Ho, Vincent T.; Koreth, John; Nikiforow, Sarah; Romee, Rizwan; Shapiro, Roman; Deangelo, Daniel J.; Stone, Richard M.; Bat-Erdene, Denbaa; Ryan, Jeremy; Contreras, Manuel E.; Fell, Geoffrey; Letai, Anthony; Ritz, Jerome; Lindsley, R. Coleman; Soiffer, Robert J.; Antin, Joseph H. Share Save
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The non-covalent HCK/BTK inhibitor TTX-114 displays potent in vitro and in vivo anti-tumor activity in leukemia and lymphoma Rauh, Ulrike; Serrano-Wu, Michael; Kaushik, Virendar; Pilari, Sabine; Ogahara, Ikuko; Kaneko, Akiko; Arribas, Alberto J.; Cannas, Eleonora; Bertoni, Franceso; Javidi-Sharifi, Nathalie R.; Davids, Matthew S.; Fukami, Takehiro; Saito, Yoriko; Ishikawa, Fumihiko; Letai, Anthony; Hubbard, Brian Share Save
Heterogeneity and transcriptional drivers of triple-negative breast cancer Jovanovic, Bojana; Temko, Daniel; Stevens, Laura E.; Seehawer, Marco; Fassl, Anne; Murphy, Katherine; Anand, Jayati; Garza, Kodie; Gulvady, Anushree; Qiu, Xintao; Harper, Nicholas W.; Daniels, Veerle W.; Huang, Xiao-Yun; Ge, Jennifer Y.; Aleckovic, Masa; Pyrdol, Jason; Hinohara, Kunihiko; Egri, Shawn B.; Papanastasiou, Malvina; Vadhi, Raga; Font-Tello, Alba; Witwicki, Robert; Peluffo, Guillermo; Trinh, Anne; Shu, Shaokun; Diciaccio, Benedetto; Ekram, Muhammad B.; Subedee, Ashim; Herbert, Zachary T.; Wucherpfennig, Kai W.; Letai, Anthony G.; Jaffe, Jacob D.; Sicinski, Piotr; Brown, Myles; Dillon, Deborah; Long, Henry W.; Michor, Franziska; Polyak, Kornelia Share Save
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Sequential apoptotic and multiplexed proteomic evaluation of single cancer cells Lecky, Emmalyn; Mukherji, Atreyi; German, Rebecca; Antonellis, Gabriella; Lin, Jia-Ren; Yorsz, Michael; McQueeney, Kelley E.; Ryan, Jeremy; Ng, Kimmie; Sicinska, Ewa; Sorger, Peter K.; Letai, Anthony; Bhola, Patrick D. Share Save
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Collateral deletion of the mitochondrial AAA plus ATPase ATAD1 sensitizes cancer cells to proteasome dysfunction Winter, Jacob M.; Fresenius, Heidi L.; Cunningham, Corey N.; Wei, Peng; Keys, Heather R.; Berg, Jordan; Bott, Alex; Yadav, Tarun; Ryan, Jeremy; Sirohi, Deepika; Tripp, Sheryl R.; Barta, Paige; Agarwal, Neeraj; Letai, Anthony; Sabatini, David M.; Wohlever, Matthew L.; Rutter, Jared Share Save
IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemia Aubrey, Brandon J.; Cutler, Jevon A.; Bourgeois, Wallace; Donovan, Katherine A.; Gu, Shengqing; Hatton, Charlie; Perlee, Sarah; Perner, Florian; Rahnamoun, Homa; Theall, Alexandra C. P.; Henrich, Jill A.; Zhu, Qian; Nowak, Radostaw P.; Kim, Young Joon; Parvin, Salma; Cremer, Anjali; Olsen, Sarah Naomi; Eleuteri, Nicholas A.; Pikman, Yana; McGeehan, Gerard M.; Stegmaier, Kimberly; Letai, Anthony; Fischer, Eric S.; Liu, X. Shirley; Armstrong, Scott A. Share Save
Combination therapy targeting Erk1/2 and CDK4/6i in relapsed refractory multiple myeloma (vol 36, pg 1088, 2021) Adamia, Sophia; Bhatt, Shruti; Wen, Kenneth; Chyra, Zuzana; Fell, Geoffrey G.; Tai, Yu-Tzu; Pioso, Marissa S.; Abiatari, Ivane; Letai, Anthony; Dorfman, David M.; Hideshima, Teru; Anderson, Kenneth C. Share Save
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