Not logged in Share Save
Discovery of Coronavirus Main Protease Inhibitors with Enhanced Brain Exposure and Potent Oral Efficacy in SARS-CoV-2 and MERS Infection Models Lizzadro, Luca; Li, Jiapeng; Taha, Taha Y.; Degotte, Gilles; Detomasi, Tyler C.; Zapatero-Belinchon, Francisco J.; Hantz, Eric R.; Huang, Sijie; Matsui, Yusuke; Henderson, Will R.; McCann, Jack T.; Montano, Mauricio; Rosecrans, Julia; Torres Pomares, Daniel F.; McGovern, Briana L.; Diaz-Tapia, Randy; Benjamin, Jared; Gordon, Mary E.; Suazo, Isidora D.; Settineri, Nicholas S.; Diallo, Amy; Krogan, Nevan J.; Shoichet, Brian K.; Verba, Kliment A.; Albrecht, Randy; Garcia-Sastre, Adolfo; White, Kris M.; Ott, Melanie; Craik, Charles S.; Renslo, Adam R. Share Save
Share Save
The Mac1 ADP-ribosylhydrolase is a therapeutic target for SARS-CoV-2 Suryawanshi, Rahul K.; Jaishankar, Priyadarshini; Correy, Galen J.; Rachman, Moira M.; O'leary, Patrick C.; Taha, Taha Y.; Matsui, Yusuke; Zapatero-Belinchon, Francisco J.; Mccavitt-Malvido, Maria; Doruk, Yagmur U.; Stevens, Maisie Gv; Diolaiti, Morgan E.; Jogalekar, Manasi P.; Chen, Huadong; Richards, Alicia L.; Kongpracha, Pornparn; Bali, Sofia; Montano, Mauricio; Rosecrans, Julia; Matthay, Michael; Togo, Takaya; Gonciarz, Ryan L.; Gopalkrishnan, Saumya; Neitz, R. Jeffrey; Krogan, Nevan J.; Swaney, Danielle L.; Shoichet, Brian K.; Ott, Melanie; Renslo, Adam R.; Ashworth, Alan; Fraser, James S. Share Save
Share Save
Structure-based discovery of highly bioavailable, covalent, broad-spectrum coronavirus MPro inhibitors with potent in vivo efficacy Detomasi, Tyler C.; Degotte, Gilles; Huang, Sijie; Suryawanshi, Rahul K.; Diallo, Amy; Lizzadro, Luca; Zaptero-Belinchon, Francisco J.; Taha, Taha Y.; Li, Jiapeng; Richards, Alicia L.; Hantz, Eric R.; Alam, Zain; Montano, Mauricio; McCavitt-Malvido, Maria; Gumpena, Rajesh; Partridge, James R.; Correy, Galen J.; Matsui, Yusuke; Charvat, Annemarie F.; Glenn, Isabella S.; Rosecrans, Julia; Revalde, Jezrael L.; Anderson, Dashiell; Hultquist, Judd F.; Arkin, Michelle R.; Neitz, R. Jeffrey; Swaney, Danielle L.; Krogan, Nevan J.; Shoichet, Brian K.; Verba, Kliment A.; Ott, Melanie; Renslo, Adam R.; Craik, Charles S. Share Save
Enhanced RNA replication and pathogenesis in recent SARS-CoV-2 variants harboring the L260F mutation in NSP6 Taha, Taha Y.; Ezzatpour, Shahrzad; Hayashi, Jennifer M.; Ye, Chengjin; Zapatero-Belinchon, Francisco J.; Rosecrans, Julia A.; Kimmerly, Gabriella R.; Chen, Irene P.; Walcott, Keith; Kurianowicz, Anna; Jorgens, Danielle M.; Chaplin, Natalie R.; Choi, Annette; Buchholz, David W.; Sahler, Julie; Hilt, Zachary T.; Imbiakha, Brian; Vagi-Szmola, Cecilia; Montano, Mauricio; Stevenson, Erica; Gordon, Martin; Swaney, Danielle L.; Krogan, Nevan J.; Whittaker, Gary R.; Martinez-Sobrido, Luis; Aguilar, Hector C.; Ott, Melanie Share Save
Torsional twist of the SARS-CoV and SARS-CoV-2 SUD-N and SUD-M domains Rosas-Lemus, Monica; Minasov, George; Brunzelle, Joseph S.; Taha, Taha Y.; Lemak, Sofia; Yin, Shaohui; Shuvalova, Ludmilla; Rosecrans, Julia; Khanna, Kanika; Seifert, H. Steven; Savchenko, Alexei; Stogios, Peter J.; Ott, Melanie; Satchell, Karla J. F. Share Save
Share Save
SARS-CoV-2 evolution balances conflicting roles of N protein phosphorylation Syed, Abdullah M.; Ciling, Alison; Chen, Irene P.; Carlson, Christopher R.; Adly, Armin N.; Martin, Hannah S.; Taha, Taha Y.; Khalid, Mir M.; Price, Nathan; Bouhaddou, Mehdi; Ummadi, Manisha R.; Moen, Jack M.; Krogan, Nevan J.; Morgan, David O.; Ott, Melanie; Doudna, Jennifer A. Share Save
Intracellular lipid droplets are exploited by Junın virus in a nucleoprotein-dependent process Vazquez, Cecilia Alejandra; Escudero-Perez, Beatriz; Hayashi, Jennifer M.; Leon, Kristoffer E.; Moreira, Joao Paulo; Catana, Mayra Alejandra Castaneda; Groseth, Allison; Ott, Melanie; Oestereich, Lisa; Munoz-Fontela, Cesar; Garcia, Cybele Carina; Cordo, Sandra Myriam Share Save
Neutralizing and binding antibody responses to SARS-CoV-2 with hybrid immunity in pregnancy Li, Lin; Matsui, Yusuke; Prahl, Mary K.; Cassidy, Arianna G.; Golan, Yarden; Jigmeddagva, Unurzul; Ozarslan, Nida; Lin, Christine Y.; Buarpung, Sirirak; Gonzalez, Veronica J.; Chidboy, Megan A.; Basilio, Emilia; Lynch, Kara L.; Song, Dongli; Jegatheesan, Priya; Rai, Daljeet S.; Govindaswami, Balaji; Needens, Jordan; Rincon, Monica; Myatt, Leslie; Taha, Taha Y.; Montano, Mauricio; Ott, Melanie; Greene, Warner C.; Gaw, Stephanie L. Share Save
Immediate myeloid depot for SARS-CoV-2 in the human lung Magnen, Melia; You, Ran; Rao, Arjun A.; Davis, Ryan T.; Rodriguez, Lauren; Bernard, Olivier; Simoneau, Camille R.; Hysenaj, Lisiena; Hu, Kenneth H.; Maishan, Mazharul; Conrad, Catharina; Gbenedio, Oghenekevwe M.; Samad, Bushra; Love, Christina; Woodruff, Prescott G.; Erle, David J.; Hendrickson, Carolyn M.; Calfee, Carolyn S.; Matthay, Michael A.; Roose, Jeroen P.; Sil, Anita; Ott, Melanie; Langelier, Charles R.; Krummel, Matthew F.; Looney, Mark R. Share Save
NF-κB inhibitor alpha controls SARS-CoV-2 infection in ACE2-overexpressing human airway organoids Simoneau, Camille R.; Chen, Pei-Yi; Xing, Galen K.; Hayashi, Jennifer M.; Chen, Irene P.; Khalid, Mir M.; Meyers, Nathan L.; Taha, Taha Y.; Leon, Kristoffer E.; Suryawanshi, Rahul K.; McCavitt-Malvido, Maria; Ashuach, Tal; Fontaine, Krystal A.; Rodriguez, Lauren; Joehnk, Bastian; Walcott, Keith; Vasudevan, Sreelakshmi; Fang, Xiaohui; Maishan, Mazharul; Schultz, Shawn; Roose, Jeroen P.; Matthay, Michael A.; Sil, Anita; Arjomandi, Mehrdad; Yosef, Nir; Ott, Melanie Share Save
Share Save
3D human tissue models and microphysiological systems for HIV and related comorbidities Yin, Dwight E.; Palin, Amy C.; Lombo, Tania B.; Mahon, Robert N., III; Poon, Betty; Wu, Da-Yu; Atala, Anthony; Brooks, Kristina M.; Chen, Shuibing; Coyne, Carolyn B.; D'Souza, M. Patricia; Fackler, Oliver T.; O'Brien, Robert L. Furler; Garcia-de-Alba, Carolina; Jean-Philippe, Patrick; Karn, Jonathan; Majji, Sai; Muotri, Alysson R.; Ozulumba, Tochukwu; Sakatis, Melanie Z.; Schlesinger, Larry S.; Singh, Anjali; Spiegel, Hans M. L.; Struble, Evi; Sung, Kyung; Tagle, Danilo A.; Thacker, Vivek V.; Tidball, Andrew M.; Varthakavi, Vasundhara; Vunjak-Novakovic, Gordana; Wagar, Lisa E.; Yeung, Catherine K.; Ndhlovu, Lishomwa C.; Ott, Melanie Share Save
CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells Rathore, Ujjwal; Haas, Paige; Kumar, Vigneshwari Easwar; Hiatt, Joseph; Haas, Kelsey M.; Bouhaddou, Mehdi; Swaney, Danielle L.; Stevenson, Erica; Zuliani-Alvarez, Lorena; McGregor, Michael J.; Turner-Groth, Autumn; Ochieng' Olwal, Charles; Bediako, Yaw; Braberg, Hannes; Soucheray, Margaret; Ott, Melanie; Eckhardt, Manon; Hultquist, Judd F.; Marson, Alexander; Kaake, Robyn M.; Krogan, Nevan J. Share Save
Assembly of SARS-CoV-2 nucleocapsid protein with nucleic acid Zhao, Huaying; Syed, Abdullah M.; Khalid, Mir M.; Nguyen, Ai; Ciling, Alison; Wu, Di; Yau, Wai-Ming; Srinivasan, Sanjana; Esposito, Dominic; Doudna, Jennifer A.; Piszczek, Grzegorz; Ott, Melanie; Schuck, Peter Share Save
Share Save
Hepatitis C virus infects and perturbs liver stem cells Meyers, Nathan L.; Ashuach, Tal; Lyons, Danielle E.; Khalid, Mir M.; Simoneau, Camille R.; Erickson, Ann L.; Bouhaddou, Mehdi; Nguyen, Thong T.; Kumar, G. Renuka; Taha, Taha Y.; Natarajan, Vaishaali; Baron, Jody L.; Neff, Norma; Zanini, Fabio; Mahmoudi, Tokameh; Quake, Stephen R.; Krogan, Nevan J.; Cooper, Stewart; Mcdevitt, Todd C.; Yosef, Nir; Ott, Melanie Share Save
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
Share.png){kind=icon}
Save
Not logged in.png){kind=icon}