Philip A. Beachy - Publications, H-index & Citations

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Philip A. Beachy

Stanford University School of Medicine

94H-index

191Paper Count

4.7WCitation Count

Published Papers 56

Publication Date

Neuroendocrine cells orchestrate regeneration through Desert hedgehog signaling

Cell

IF42.5

2025-06-09

PREAI

William Kong; Wan-Jin Lu; Megha Dubey; Rahul K. Suryawanshi; Sivakamasundari Vijayakumar; Youngtae Jeong; Saurabh Gombar; Maximilian Diehn; Kunyoo Shin; Melanie Ott; Yueh-hsiu Chien; Kavita Y. Sarin; Tushar J. Desai; Philip A. Beachy

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Localized application of SAG21k-loaded fibrin hydrogels for targeted modulation of the hedgehog pathway in facial nerve injury

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2024-06-01

PREAI

He, Lili; Sato, Justine Esther; Sundar, Praveen; Azimi, Tannaz; Beachy, Philip Arden; Bekale, Laurent Adonis; Pepper, Jon-Paul

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Cellular and molecular mechanisms of Hedgehog signalling

NATURE REVIEWS MOLECULAR CELL BIOLOGY

IF90.2

2023-03-17

PREAI

Zhang, Yunxiao; Beachy, Philip A.

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Identification of a minority population of LMO2+ breast cancer cells that integrate into the vasculature and initiate metastasis

SCIENCE ADVANCES

IF12.5

2022-11-11

OAAI

Sikandar, Shaheen S.; Gulati, Gunsagar S.; Antony, Jane; Fetter, Isobel; Kuo, Angera H.; Ho, William Hai Dang; Haro-Acosta, Veronica; Das, Soumyashree; Steen, Chloe B.; Pereira, Thiago Almeida; Qian, Dalong; Beachy, Philip A.; Dirbas, Fredrick; Red-Horse, Kristy; Rabbitts, Terence H.; Thiery, Jean Paul; Newman, Aaron M.; Clarke, Michael F.

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Hedgehog pathway activation through nanobody-mediated conformational blockade of the Patched sterol conduit

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-11-02

OAAI

Zhang, Yunxiao; Lu, Wan-Jin; Bulkley, David P.; Liang, Jiahao; Ralko, Arthur; Han, Shuo; Roberts, Kelsey J.; Li, Anping; Cho, Wonhwa; Cheng, Yifan; Manglik, Aashish; Beachy, Philip A.

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Cilia-Associated Oxysterols Activate Smoothened

MOLECULAR CELL

IF16.6

2018-10-01

100

OAAI

Raleigh, David R.; Sever, Navdar; Choksi, Pervinder K.; Sigg, Monika Abedin; Hines, Kelly M.; Thompson, Bonne M.; Elnatan, Daniel; Jaishankar, Priyadarshini; Bisignano, Paola; Garcia-Gonzalo, Francesc R.; Krup, Alexis Leigh; Eberl, Markus; Byrne, Eamon F. X.; Siebold, Christian; Wong, Sunny Y.; Renslo, Adam R.; Grabe, Michael; McDonald, Jeffrey G.; Xu, Libin; Beachy, Philip A.; Reiter, Jeremy F.

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Neuronal delivery of Hedgehog directs spatial patterning of taste organ regeneration

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-12-26

OAAI

Lu, Wan-Jin; Mann, Randall K.; Nguyen, Allison; Bi, Tingting; Silverstein, Max; Tang, Jean Y.; Chen, Xiaoke; Beachy, Philip A.

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Rapid, direct activity assays for Smoothened reveal Hedgehog pathway regulation by membrane cholesterol and extracellular sodium

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-12-11

112

OAAI

Myers, Benjamin R.; Neahring, Lila; Zhang, Yunxiao; Roberts, Kelsey J.; Beachy, Philip A.

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Hedgehog mediated degradation of Ihog adhesion proteins modulates cell segregation in Drosophila wing imaginal discs

NATURE COMMUNICATIONS

IF15.7

2017-11-02

OAAI

Hsia, Elaine Y. C.; Zhang, Ya; Tran, Hai Son; Lim, Agnes; Chou, Ya-Hui; Lan, Ganhui; Beachy, Philip A.; Zheng, Xiaoyan

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Pharmacological rescue of diabetic skeletal stem cell niches

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2017-01-11

OAAI

Tevlin, Ruth; Seo, Eun Young; Marecic, Owen; McArdle, Adrian; Tong, Xinming; Zimdahl, Bryan; Malkovskiy, Andrey; Sinha, Rahul; Gulati, Gunsagar; Li, Xiyan; Wearda, Taylor; Morganti, Rachel; Lopez, Michael; Ransom, Ryan C.; Duldulao, Christopher R.; Rodrigues, Melanie; Nguyen, Allison; Januszyk, Michael; Maan, Zeshaan; Paik, Kevin; Yapa, Kshemendra-Senarath; Rajadas, Jayakumar; Wan, Derrick C.; Gurtner, Geoffrey C.; Snyder, Michael; Beachy, Philip A.; Yang, Fan; Goodman, Stuart B.; Weissman, Irving L.; Chan, Charles K. F.; Longaker, Michael T.

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Role of KEAP1/NRF2 and TP53 Mutations in Lung Squamous Cell Carcinoma Development and Radiation Resistance

CANCER DISCOVERY

IF33.3

2017-01-05

267

OAAI

Jeong, Youngtae; Hoang, Ngoc T.; Lovejoy, Alexander; Stehr, Henning; Newman, Aaron M.; Gentles, Andrew J.; Kong, William; Diana Truong; Martin, Shanique; Chaudhuri, Aadel; Heiser, Diane; Zhou, Li; Say, Carmen; Carter, Justin N.; Hiniker, Susan M.; Loo, Billy W., Jr.; West, Robert B.; Beachy, Philip; Alizadeh, Ash A.; Diehn, Maximilian

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Control of inflammation by stromal Hedgehog pathway activation restrains colitis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-11-04

OAAI

Lee, John J.; Rothenberg, Michael E.; Seeley, E. Scott; Zimdahl, Bryan; Kawano, Sally; Lu, Wan-Jin; Shin, Kunyoo; Sakata-Kato, Tomoyo; Chen, James K.; Diehn, Maximilian; Clarke, Michael F.; Beachy, Philip A.

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Hsd11β2 Is Enriched in Medulloblastoma and Generates Ciliary Oxysterols to Stimulate Hedgehog Signaling

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

IF6.5

2016-10-01

OAAI

Raleigh, D.; Sever, N.; Sigg, M. A.; Garcia-Gonzalo, F. R.; Choksi, P. K.; Hines, K. M.; Choksi, S. P.; Krup, A. L.; McDonald, J. G.; Xu, L.; Beachy, P. A.; Reiter, J. F.

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Topical Itraconazole inhibits the Hedgehog signaling pathway and reduces tumor development and size in murine models

JOURNAL OF INVESTIGATIVE DERMATOLOGY

IF5.7

2016-08-01

OAAI

Fry, M.; Teng, C.; Lee, A.; Sun, W.; Parekh, M.; Rajadas, J.; Beachy, P.; Epstein, E.; Tang, J.

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Endogenous B-ring oxysterols inhibit the Hedgehog component Smoothened in a manner distinct from cyclopamine or side-chain oxysterols

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-05-09

OAAI

Sever, Navdar; Mann, Randall K.; Xu, Libin; Snell, William J.; Hernandez-Lara, Carmen I.; Porter, Ned A.; Beachy, Philip A.

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Effects of Combined Treatment With Arsenic Trioxide and Itraconazole in Patients With Refractory Metastatic Basal Cell Carcinoma

JAMA DERMATOLOGY

IF11

2016-04-01

OAAI

Ally, Mina S.; Ransohoff, Katherine; Sarin, Kavita; Atwood, Scott X.; Rezaee, Melika; Bailey-Healy, Irene; Kim, Jynho; Beachy, Philip A.; Chang, Anne Lynn S.; Oro, Anthony; Tang, Jean Y.; Colevas, A. Dimitrios

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Localized JNK signaling regulates organ size during development

ELIFE

IF0

2016-03-14

OAAI

Willsey, Helen Rankin; Zheng, Xiaoyan; Pastor-Pareja, Jose Carlos; Willsey, A. Jeremy; Beachy, Philip A.; Xu, Tian

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The role of ciliary trafficking in Hedgehog receptor signaling

SCIENCE SIGNALING

IF6.6

2015-06-02

OAAI

Kim, Jynho; Hsia, Elaine Y. C.; Brigui, Amira; Plessis, Anne; Beachy, Philip A.; Zheng, Xiaoyan

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Itraconazole Inhibits Enterovirus Replication by Targeting the Oxysterol-Binding Protein

CELL REPORTS

IF6.9

2015-02-01

213

OAAI

Strating, Jeroen R. P. M.; van der Linden, Lonneke; Albulescu, Lucian; Bigay, Joelle; Arita, Minetaro; Delang, Leen; Leyssen, Pieter; van der Schaar, Hilde M.; Lanke, Kjerstin H. W.; Thibaut, Hendrik Jan; Ulferts, Rachel; Drin, Guillaume; Schlinck, Nina; Wubbolts, Richard W.; Sever, Navdar; Head, Sarah A.; Liu, Jun O.; Beachy, Philip A.; De Matteis, Maria A.; Shair, Matthew D.; Olkkonen, Vesa M.; Neyts, Johan; van Kuppeveld, Frank J. M.

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Identification of recurrent SMO and BRAF mutations in ameloblastomas (vol 46, pg 722, 2014)

NATURE GENETICS

IF31.8

2014-12-30

OAAI

Sweeney, Robert T.; McClary, Andrew C.; Myers, Benjamin R.; Biscocho, Jewison; Neahring, Lila; Kwei, Kevin A.; Qu, Kunbin; Gong, Xue; Ng, Tony; Jones, Carol D.; Varma, Sushama; Odegaard, Justin I.; Sugiyama, Toshihiro; Koyota, Souichi; Rubin, Brian P.; Troxell, Megan L.; Pelham, Robert J.; Zehnder, James L.; Beachy, Philip A.; Pollack, Jonathan R.; West, Robert B.

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Research Directions