Nancy E. Hynes - Publications, H-index & Citations

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Nancy E. Hynes

Friedrich Miescher Institute for Biomedical Research

78H-index

334Paper Count

2.3WCitation Count

Published Papers 96

Publication Date

Tumor-associated neutrophil precursors impair homologous DNA repair and promote sensitivity to PARP inhibition

Nature Communications

IF15.7

2025-07-30

OAAI

Siddhartha Mukherjee; Cindy Garda; Letizia Boffa; Angela Rita Elia; Matteo Massara; Maria Teresa Balia; Daniela Brina; Simone Mosole; Anna Campagnari; Giada Andrea Cassanmagnago; Andrea Rinaldi; Giacomo Lazzaroni; David Jarrossay; Diego Morone; Ilaria Ceppi; Riccardo De Sillo; Isabella Giacomini; Ilaria Craparotta; Laura Di Rito; Simon Barry; Endre Laczko; Sebastian Streb; Francesco Meani; Simona Di Lascio; Nancy Hynes; Enrico Lugli; Simone Puccio; Stephen-John Sammut; Ulrike Perriard; Yves Harder; Lorenzo Rossi; Maria Luisa Gasparri; Marco Bolis; Petr Cejka; Arianna Calcinotto

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HER4 mediates ligand-dependent antiproliferative and differentiation responses in human breast cancer cells

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

176

OAAI

Sartor, CI; Zhou, H; Kozlowska, E; Guttridge, K; Kawata, E; Caskey, L; Harrelson, J; Hynes, N; Ethier, S; Calvo, B; Earp, HS

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ErbB-1 and ErbB-2 acquire distinct signaling properties dependent upon their dimerization partner

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

249

OAAI

Olayioye, MA; Graus-Porta, D; Beerli, RR; Rohrer, J; Gay, B; Hynes, NE

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ErbB2 potentiates breast tumor proliferation through modulation of p27Kip1-Cdk2 complex formation:: Receptor overexpression does not determine growth dependency

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

320

OAAI

Lane, HA; Beuvink, I; Motoyama, AB; Daly, JM; Neve, RM; Hynes, NE

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Characterization of Stat5a and Stat5b homodimers and heterodimers and their association with the glucocortiocoid receptor in mammary cells

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

154

OAAI

Cella, N; Groner, B; Hynes, NE

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Renal FGF23 signaling depends on redox protein Memo1 and promotes orthovanadate-sensitive protein phosphotyrosyl phosphatase activity

cell communication and signaling

IF3.9

2022-11-25

OAAI

Bartos, Katalin; Ramakrishnan, Suresh Krishna; Braga-Lagache, Sophie; Hanzi, Barbara; Durussel, Fanny; Sridharan, Arjun Prakash; Zhu, Yao; Sheehan, David; Hynes, Nancy E.; Bonny, Olivier; Moor, Matthias B.

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Aberrant RET expression affects normal mammary gland post-lactation transition, enhancing cancer potential

DISEASE MODELS & MECHANISMS

IF3.3

2022-03-29

OAAI

Vallone, Sabrina A.; Garcia Sola, Martin; Schere-Levy, Carolina; Meiss, Roberto P.; Hermida, Gladys N.; Chodosh, Lewis A.; Kordon, Edith C.; Hynes, Nancy E.; Gattelli, Albana

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Sustained Ret expression during mammary gland post-lactation induces premature involution and enhances cancer potential

CANCER RESEARCH

IF16.6

2020-08-15

PREAI

Vallone, Sabrina A.; Garcia Sola, Martin; Cardiff, Robert D.; Meiss, Roberto P.; Chodosh, Lewis A.; Shere-Levy, Carolina; Kordon, Edith C. C.; Hynes, Nancy E.; Gattelli, Albana

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Ret Receptor Has Distinct Alterations and Functions in Breast Cancer

JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

IF3.6

2020-02-21

PREAI

Gattelli, Albana; Hynes, Nancy E.; Schor, Ignacio E.; Vallone, Sabrina A.

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Renal Memo1 Differentially Regulates the Expression of Vitamin D-Dependent Distal Renal Tubular Calcium Transporters

FRONTIERS IN PHYSIOLOGY

IF3.4

2018-07-09

OAAI

Moor, Matthias B.; Haenzi, Barbara; Legrand, Finola; Koesters, Robert; Hynes, Nancy E.; Bonny, Olivier

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Chronic expression of wild-type Ret receptor in the mammary gland induces luminal tumors that are sensitive to Ret inhibition

ONCOGENE

IF7.3

2018-04-26

PREAI

Gattelli, Albana; Garcia Sola, Martin E.; Roloff, Tim C.; Cardiff, Robert D.; Kordon, Edith C.; Chodosh, Lewis A.; Hynes, Nancy E.

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SYK inhibition blocks proliferation and migration of glioma cells and modifies the tumor microenvironment

NEURO-ONCOLOGY

IF13.4

2018-02-01

OAAI

Moncayo, Gerald; Grzmil, Michal; Smirnova, Tatiana; Zmarz, Pawel; Huber, Roland M.; Hynx, Debby; Kohler, Hubertus; Wang, Yuhua; Hotz, Hans-Rudolf; Hynes, Nancy E.; Keller, Georg; Frank, Stephan; Merlo, Adrian; Hemmings, Brian A.

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NADPH oxidase-mediated redox signaling promotes oxidative stress resistance and longevity through memo-1 in C. elegans

ELIFE

IF0

2017-01-13

OAAI

Ewald, Collin Yves; Hourihan, John M.; Bland, Monet S.; Obieglo, Carolin; Katic, Iskra; Mazzeo, Lorenza E. Moronetti; Alcedo, Joy; Blackwell, T. Keith; Hynes, Nancy E.

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Decreased NK-cell tumour immunosurveillance consequent to JAK inhibition enhances metastasis in breast cancer models

NATURE COMMUNICATIONS

IF15.7

2016-07-13

OAAI

Bottos, Alessia; Gotthardt, Dagmar; Gill, Jason W.; Gattelli, Albana; Frei, Anna; Tzankov, Alexandar; Sexl, Veronika; Wodnar-Filipowicz, Aleksandra; Hynes, Nancy E.

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ErbB2: From an EGFR Relative to a Central Target for Cancer Therapy

CANCER RESEARCH

IF16.6

2016-06-30

OAAI

Hynes, Nancy E.

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The seventh ENBDC workshop on methods in mammary gland development and cancer

BREAST CANCER RESEARCH

IF5.6

2015-09-02