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OPERATIONAL STRATEGIES AND REGULATORY NAVIGATION OF AN ACADEMIC CAR T-CELL TRIAL FOR GLIOBLASTOMA: EXPERIENCE FROM THE E-SYNC STUDY Yamamichi, Akane; Watchmaker, Payal; Almeida, Ricardo; Simic, Milos; Shy, Brian; Kong, Dehui; Houser, Derrick; Paruthiyil, Sreenivasan; Acevedo, Luis; Phillips, Joanna; Hansen, Abigail; Kumar-Wessel, Karishma; Young, Jacob; Nejo, Takahide; Lim, Wendell; Clarke, Jennifer L.; Okada, Hideho Share Save
Synthetic organizer cells guide development via spatial and biochemical instructions Yamada, Toshimichi; Trentesaux, Coralie; Brunger, Jonathan M.; Xiao, Yini; Stevens, Adam J.; Martyn, Iain; Kasparek, Petr; Shroff, Neha P.; Aguilar, Angelica; Bruneau, Benoit G.; Boffelli, Dario; Klein, Ophir D.; Lim, Wendell A. Share Save
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NOVEL CNS SENSING SYNNOTCH-CAR T CELLS FOR TARGETING DIFFUSE MIDLINE GLIOMA Lakshmanachetty, Senthilnath; Simic, Milos; Haegelin, Jeffrey; Watchmaker, Payal; Long, Haoyu; Deucker, Jason; Zhu, Robert; Sheperd, Chanelle; Yu, Wei; Ng, Ben; Wang, Yuan; Troyanskaya, Olga; Cardarelli, Lia; Sidhu, Sachdev; Lim, Wendell; Okada, Hideho Share Save
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An immune-based tool platform for in vivo cell clearance Zhang, Jieqiong; Tsukui, Tatsuya; Wu, Xiumin; Brito, Alyssa; Trumble, John Maxwell; Caraballo, Juan C.; Allen, Greg M.; Zavala-Solorio, Jose; Zhang, Chunlian; Paw, Jonathan; Lim, Wendell A.; Geng, Jiefei; Kutskova, Yuliya; Freund, Adam; Kolumam, Ganesh; Sheppard, Dean; Cohen, Robert L. Share Save
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CAR-T Cell-Mediated B-Cell Depletion in Central Nervous System Autoimmunity Gupta, Sasha; Simic, Milos; Sagan, Sharon A.; Shepherd, Chanelle; Duecker, Jason; Sobel, Raymond A.; Dandekar, Ravi; Wu, Gregory F.; Wu, Wesley; Pak, John E.; Hauser, Stephen L.; Lim, Wendell; Wilson, Michael R.; Zamvil, Scott S. Share Save
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PRIMING OF SYNNOTCH CAR T CELLS VIA CNS-SPECIFIC ANTIGEN ALLOWS SPATIAL AND TEMPORAL REGULATION OF CAR EXPRESSION, EFFECTIVE HOMING AND PERSISTENCE OF T CELLS IN THE CNS, RESULTING IN THE COMPLETE ERADICATION OF AGGRESIVE GLIOBLASTOMA Watchmaker, Payal; Simic, Milos; Diebold, David; Pineo-Cavanaugh, Psalm; Duecker, Jason; Yu, Wei; Lim, Wendell; Okada, Hideho Share Save
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SynNotch-CAR T cells overcome challenges of specificity, heterogeneity, and persistence in treating glioblastoma Choe, Joseph H.; Watchmaker, Payal B.; Simic, Milos S.; Gilbert, Ryan D.; Li, Aileen W.; Krasnow, Nira A.; Downey, Kira M.; Yu, Wei; Carrera, Diego A.; Celli, Anna; Cho, Juhyun; Briones, Jessica D.; Duecker, Jason M.; Goretsky, Yitzhar E.; Dannenfelser, Ruth; Cardarelli, Lia; Troyanskaya, Olga; Sidhu, Sachdev S.; Roybal, Kole T.; Okada, Hideho; Lim, Wendell A. Share Save
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DNA scaffolds enable efficient and tunable functionalization of biomaterials for immune cell modulation Huang, Xiao; Williams, Jasper Z.; Chang, Ryan; Li, Zhongbo; Burnett, Cassandra E.; Hernandez-Lopez, Rogelio; Setiady, Initha; Gai, Eric; Patterson, David M.; Yu, Wei; Roybal, Kole T.; Lim, Wendell A.; Desai, Tejal A. Share Save
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Discriminatory Power of Combinatorial Antigen Recognition in Cancer T Cell Therapies Dannenfelser, Ruth; Allen, Gregory M.; VanderSluis, Benjamin; Koegel, Ashley K.; Levinson, Sarah; Stark, Sierra R.; Yao, Vicky; Tadych, Alicja; Troyanskaya, Olga G.; Lim, Wendell A. Share Save
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