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Targeting Oxalate Production by Combining Enzyme Inhibition and Proteolysis Activation: A Novel Therapeutic Approach for Primary Hyperoxaluria Type 1 Arias, Fabio; Rohilla, Sumati; Sixto-Lopez, Yudibeth; Richard, Koral S. E.; Das, Sandeep; Anand, Sumit K.; Luque-Navarro, Pilar Maria; Banuelos-Sanchez, Guillermo; Pacheco-Garcia, Juan Luis; Gade, Reethika; Mckinney, M. Peyton; Kumar, Dhananjay; Maxie, Jemiah; Corr, W. Rylan; Pandey, Nilesh; Kaur, Harpreet; Ding, Jibin; Tan, Lin; Scott, Elisha; Nam, Hyung; Gottlieb, Eyal; Orr, A. Wayne; Dhanesha, Nirav; Yurdagul Jr, Arif; Pey, Angel L.; Franco-Montalban, Francisco; Gomez Vidal, Jose A.; Rom, Oren; Diaz-Gavilan, Monica Share Save
A step-by-step guide to performing cancer metabolism research using custom-made media Seifert, Sophie; Yanqui-Rivera, Francisco; Kuhn, Tim; Hoyland, Lena Elise; Bortecen, Toman; Agranovich, Bella; Eckhardt, Lara Elea; Herdt, Martin; Henneberg, Alessa; Panitz, Verena; Hayat, Faisal; Migaud, Marie; Poschet, Gernot; Abramovich, Ifat; Gottlieb, Eyal; Krijgsveld, Jeroen; Ziegler, Mathias; Prentzell, Mirja Tamara; Opitz, Christiane A. Share Save
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A metabolic switch to the pentose-phosphate pathway induces radiation resistance in pancreatic cancer Shimoni-Sebag, Ariel; Abramovich, Ifat; Agranovich, Bella; Massri, Rami; Stossel, Chani; Atias, Dikla; Raites-Gurevich, Maria; Yizhak, Keren; Golan, Talia; Gottlieb, Eyal; Lawrence, Yaacov Richard Share Save
Inhibition of hepatic oxalate overproduction ameliorates metabolic dysfunction-associated steatohepatitis Das, Sandeep; Finney, Alexandra C.; Anand, Sumit Kumar; Rohilla, Sumati; Liu, Yuhao; Pandey, Nilesh; Ghrayeb, Alia; Kumar, Dhananjay; Nunez, Kelley; Liu, Zhipeng; Arias, Fabio; Zhao, Ying; Pearson-Gallion, Brenna H.; McKinney, M. Peyton; Richard, Koral S. E.; Gomez-Vidal, Jose A.; Abdullah, Chowdhury S.; Cockerham, Elizabeth D.; Eniafe, Joseph; Yurochko, Andrew D.; Magdy, Tarek; Pattillo, Christopher B.; Kevil, Christopher G.; Razani, Babak; Bhuiyan, Md. Shenuarin; Seeley, Erin H.; Galliano, Gretchen E.; Wei, Bo; Tan, Lin; Mahmud, Iqbal; Surakka, Ida; Garcia-Barrio, Minerva T.; Lorenzi, Philip L.; Gottlieb, Eyal; Salido, Eduardo; Zhang, Jifeng; Orr, A. Wayne; Liu, Wanqing; Diaz-Gavilan, Monica; Chen, Y. Eugene; Dhanesha, Nirav; Thevenot, Paul T.; Cohen, Ari J.; Yurdagul Jr, Arif; Rom, Oren Share Save
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Diet-omics in the Study of Urban and Rural Crohn disease Evolution (SOURCE) cohort Braun, Tzipi; Feng, Rui; Amir, Amnon; Levhar, Nina; Shacham, Hila; Mao, Ren; Hadar, Rotem; Toren, Itamar; Algavi, Yadid; Abu-Saad, Kathleen; Zhuo, Shuoyu; Efroni, Gilat; Malik, Alona; Picard, Orit; Yavzori, Miri; Agranovich, Bella; Liu, Ta-Chiang; Stappenbeck, Thaddeus S.; Denson, Lee; Kalter-Leibovici, Ofra; Gottlieb, Eyal; Borenstein, Elhanan; Elinav, Eran; Chen, Minhu; Ben-Horin, Shomron; Haberman, Yael Share Save
Serine Hydroxymethyltransferase 2 In Hepatocytes Regulates One-carbon Metabolism, Circulating VLDL And Atherosclerosis McKinney, Mary P.; Ghrayeb, Alia; Finney, Alexandra; Anand, Sumit K.; Rohilla, Sumati; Das, Sandeep; Pearson-gallion, Brenna; Tan, Lin; Lorenzi, Philip; Orr, Wayne W.; Yurdagul, Arif; Mor, Inbal; Gottlieb, Eyal; Rom, Oren Share Save
Loss Of Serine Hydroxymethyltransferase 2 In Macrophages Blunts Glutathione And Enhances Ceramide Synthesis To Accelerate Atherosclerosis Rohilla, Sumati; Ghrayeb, Alia; Finney, Alexandra C.; McKinney, M. Peyton; Liu, Yuhao; Nam, Hugh; Tan, Lin; Lorenzi, Philip L.; Mor, Inbal; Orr, A. Wayne; Gottlieb, Eyal; Yurdagul, Arif, Jr.; Rom, Oren Share Save
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Programming a Ferroptosis-to-Apoptosis Transition Landscape Revealed Ferroptosis Biomarkers and Repressors for Cancer Therapy Vinik, Yaron; Maimon, Avi; Dubey, Vinay; Raj, Harsha; Abramovitch, Ifat; Malitsky, Sergey; Itkin, Maxim; Ma'ayan, Avi; Westermann, Frank; Gottlieb, Eyal; Ruppin, Eytan; Lev, Sima Share Save
Failure to mate enhances investment in behaviors that may promote mating reward and impairs the ability to cope with stressors via a subpopulation of Neuropeptide F receptor neurons Ryvkin, Julia; Omesi, Liora; Kim, Yong-Kyu; Levi, Mali; Pozeilov, Hadar; Barak-Buchris, Lital; Agranovich, Bella; Abramovich, Ifat; Gottlieb, Eyal; Jacob, Avi; Naessel, Dick R.; Heberlein, Ulrike; Shohat-Ophir, Galit Share Save
Serine synthesis via reversed SHMT2 activity drives glycine depletion and acetaminophen hepatotoxicity in MASLD Ghrayeb, Alia; Finney, Alexandra C.; Agranovich, Bella; Peled, Daniel; Anand, Sumit Kumar; Mckinney, M. Peyton; Sarji, Mahasen; Yang, Dongshan; Weissman, Natan; Drucker, Shani; Fernandes, Sara Isabel; Fernandez-Garcia, Jonatan; Mahan, Kyle; Abassi, Zaid; Tan, Lin; Lorenzi, Philip L.; Traylor, James; Zhang, Jifeng; Abramovich, Ifat; Chen, Y. Eugene; Rom, Oren; Mor, Inbal; Gottlieb, Eyal Share Save
Inhibition of the proline metabolism rate-limiting enzyme P5CS allows proliferation of glutamine-restricted cancer cells Linder, Samantha J.; Bernasocchi, Tiziano; Martinez-Pastor, Barbara; Sullivan, Kelly D.; Galbraith, Matthew D.; Lewis, Caroline A.; Ferrer, Christina M.; Boon, Ruben; Silveira, Giorgia G.; Cho, Hyo Min; Vidoudez, Charles; Shroff, Stuti; Oliveira-Costa, Joao P.; Ross, Kenneth N.; Massri, Rami; Matoba, Yusuke; Kim, Eugene; Rueda, Bo R.; Stott, Shannon L.; Gottlieb, Eyal; Espinosa, Joaquin M.; Mostoslavsky, Raul Share Save
Impairment of serine transport across the blood-brain barrier by deletion of Slc38a5 causes developmental delay and motor dysfunction Radzishevsky, Inna; Odeh, Maali; Bodner, Oded; Zubedat, Salman; Shaulov, Lihi; Litvak, Maxim; Esaki, Kayoko; Yoshikawa, Takeo; Agranovich, Bella; Li, Wen-Hong; Radzishevsky, Alex; Gottlieb, Eyal; Avital, Avi; Wolosker, Herman Share Save
Regulation of nucleo-cytosolic 26S proteasome translocation by aromatic amino acids via mTOR is essential for cell survival under stress Livneh, Ido; Cohen-Kaplan, Victoria; Fabre, Bertrand; Abramovitch, Ifat; Chen, Lulu; Nataraj, Nishanth Belugali; Lazar, Ikrame; Ziv, Tamar; Yarden, Yosef; Zohar, Yaniv; Gottlieb, Eyal; Ciechanover, Aaron Share Save
Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells Rattigan, Kevin M.; Brabcova, Zuzana; Sarnello, Daniele; Zarou, Martha M.; Roy, Kiron; Kwan, Ryan; de Beauchamp, Lucie; Dawson, Amy; Ianniciello, Angela; Khalaf, Ahmed; Kalkman, Eric R.; Scott, Mary T.; Dunn, Karen; Sumpton, David; Michie, Alison M.; Copland, Mhairi; Tardito, Saverio; Gottlieb, Eyal; Helgason, G. Vignir Share Save
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