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Adaptive evolution of drug responses to monotherapy ONC201 in PDOX models of pediatric brain tumors Chen, Jinnan; Abdallah, Aalaa; Palacios, Milagros Suarez; Zhai, Xin; Hang, Zilu; Jiang, Tongchao; Ciolak, Emily; Hoesley, Aria; Mei, Yiming; Bellis, James; Wadhwani, Nitin; Lenzen, Alicia; Kwon, Jee Young; Neuhauser, Steve; Stearns, Tim; Chuang, Jeff; Jocoy, Emily; Bult, Carol; Teicher, Beverly; Smith, Malcolm; Li, Xiaonan; Du, Yuchen Share Save
The CD123 antibody-drug conjugate pivekimab sunirine exerts profound activity in preclinical models of pediatric acute lymphoblastic leukemia Watts, Ben; Smith, Christopher M.; Evans, Kathryn; Gifford, Andrew J.; Mohamed, Sara M. A.; Erickson, Stephen W.; Earley, Eric J.; Neuhauser, Steven; Stearns, Timothy M.; Philip, Vivek M.; Chuang, Jeffrey H.; Zweidler-McKay, Patrick A.; Lakshmikanthan, Sribalaji; Jocoy, Emily L.; Bult, Carol J.; Teicher, Beverly A.; Smith, Malcolm A. Share Save
The novel ATR inhibitor elimusertib is efficacious as monotherapy and in combination with radiation in pdox models of pediatric high-grade glioma Palacios, M. Suarez; Du, Y.; Xiao, S.; Abdallah, A.; Zhai, X.; Ciolak, E.; Huang, Z.; Kalapurakal, J.; Wadhwani, N.; Lenzen, A.; Kwon, J. Y.; Neuhauser, S.; Stearns, T.; Chuang, J.; Jocoy, E. L.; Bult, C.; Teicher, B.; Smith, M. A.; Li, X. N. Share Save
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Multicenter histology image integration and multiscale deep learning for pediatric sarcoma subtype classification Thiesen, Adam H.; Domanskyi, Sergii; Pour, Ali Foroughi; Sheridan, Todd B.; Neuhauser, Steven B.; Stetson, Alyssa; Dannheim, Katelyn; Cameron, Danielle B.; Ahn, Shawn; Wu, Hao; Christison-Lagay, Emily R.; Bult, Carol J.; Chuang, Jeffrey H.; Rubinstein, Jill C. Share Save
A Pan-Cancer Patient-Derived Xenograft Histology Image Repository with Genomic and Pathologic Annotations Enables Deep Learning Analysis White, Brian S.; Woo, Xing Yi; Koc, Soner; Sheridan, Todd; Neuhauser, Steven B.; Wang, Shidan; Evrard, Yvonne A.; Chen, Li; Pour, Ali Foroughi; Landua, John D.; Mashl, R. Jay; Davies, Sherri R.; Fang, Bingliang; Rosa, Maria Gabriela; Evans, Kurt W.; Bailey, Matthew H.; Chen, Yeqing; Xiao, Min; Rubinstein, Jill C.; Sanderson, Brian J.; Lloyd, Michael W.; Domanskyi, Sergii; Dobrolecki, Lacey E.; Fujita, Maihi; Fujimoto, Junya; Xiao, Guanghua; Fields, Ryan C.; Mudd, Jacqueline L.; Xu, Xiaowei; Hollingshead, Melinda G.; Jiwani, Shahanawaz; Acevedo, Saul; Davis-Dusenbery, Brandi N.; Robinson, Peter N.; Moscow, Jeffrey A.; Doroshow, James H.; Mitsiades, Nicholas; Kaochar, Salma; Pan, Chong-xian; Carvajal-Carmona, Luis G.; Welm, Alana L.; Welm, Bryan E.; Govindan, Ramaswamy; Li, Shunqiang; Davies, Michael A.; Roth, Jack A.; Meric-Bernstam, Funda; Xie, Yang; Herlyn, Meenhard; Ding, Li; Lewis, Michael T.; Bult, Carol J.; Dean II, Dennis A.; Chuang, Jeffrey H. Share Save
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Minimum information and guidelines for reporting a multiplexed assay of variant effect Claussnitzer, Melina; Parikh, Victoria N.; Wagner, Alex H.; Arbesfeld, Jeremy A.; Bult, Carol J.; Firth, Helen V.; Muffley, Lara A.; Ba, Alex N. Nguyen; Riehle, Kevin; Roth, Frederick P.; Tabet, Daniel; Bolognesi, Benedetta; Glazer, Andrew M.; Rubin, Alan F. Share Save
In vivo efficacy of anti-B7-H3 antibody-drug conjugate (ADC) ifinatamab deruxtecan (I-DXd; DS-7300): An update from the Pediatric Preclinical In Vivo Testing (PIVOT) Program Gorlick, Richard; Gill, Jonathan; Zhang, Wendong; Mosse, Yael; Maris, John; Groff, David; Smith, Malcolm; Teicher, Beverly; Neuhauser, Steve; Stearns, Tim; Philip, Vivek; Jocoy, Emily; Chuang, Jeff; Bult, Carol J.; Hasegawa, Jun; Qian, Xiaozhong; Houghton, Peter; Kurmasheva, Raushan Share Save
Updates to the Alliance of Genome Resources central infrastructure Aleksander, Suzanne A.; Anagnostopoulos, Anna V.; Antonazzo, Giulia; Arnaboldi, Valerio; Attrill, Helen; Becerra, Andres; Bello, Susan M.; Blodgett, Olin; Bradford, Yvonne M.; Bult, Carol J.; Cain, Scott; Calvi, Brian R.; Carbon, Seth; Chan, Juancarlos; Chen, Wen J.; Cherry, J. Michael; Cho, Jaehyoung; Crosby, Madeline A.; De Pons, Jeffrey L.; D'Eustachio, Peter; Diamantakis, Stavros; Dolan, Mary E.; dos Santos, Gilberto; Dyer, Sarah; Ebert, Dustin; Engel, Stacia R.; Fashena, David; Fisher, Malcolm; Foley, Saoirse; Gibson, Adam C.; Gollapally, Varun R.; Gramates, L. Sian; Grove, Christian A.; Hale, Paul; Harris, Todd; Hayman, G. Thomas; Hu, Yanhui; James-Zorn, Christina; Karimi, Kamran; Karra, Kalpana; Kishore, Ranjana; Kwitek, Anne E.; Laulederkind, Stanley J. F.; Lee, Raymond; Longden, Ian; Luypaert, Manuel; Markarian, Nicholas; Marygold, Steven J.; Matthews, Beverley; McAndrews, Monica S.; Millburn, Gillian; Miyasato, Stuart; Motenko, Howie; Moxon, Sierra; Muller, Hans-Michael; Mungall, Christopher J.; Muruganujan, Anushya; Mushayahama, Tremayne; Nash, Robert S.; Nuin, Paulo; Paddock, Holly; Pells, Troy; Perrimon, Norbert; Pich, Christian; Quinton-Tulloch, Mark; Raciti, Daniela; Ramachandran, Sridhar; Richardson, Joel E.; Gelbart, Susan Russo; Ruzicka, Leyla; Schindelman, Gary; Shaw, David R.; Sherlock, Gavin; Shrivatsav, Ajay; Singer, Amy; Smith, Constance M.; Smith, Cynthia L.; Smith, Jennifer R.; Stein, Lincoln; Sternberg, Paul W.; Tabone, Christopher J.; Thomas, Paul D.; Thorat, Ketaki; Thota, Jyothi; Tomczuk, Monika; Trovisco, Vitor; Tutaj, Marek A.; Urbano, Jose-Maria; Van Auken, Kimberly; Van Slyke, Ceri E.; Vize, Peter D.; Wang, Qinghua; Weng, Shuai; Westerfield, Monte; Wilming, Laurens G.; Wong, Edith D.; Wright, Adam; Yook, Karen; Zhou, Pinglei; Zorn, Aaron; Zytkovicz, Mark Share Save
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The ROR1 antibody-drug conjugate, MK-2140, enhances the efficacy of established drugs in preclinical models of pediatric acute lymphoblastic leukemia Lock, Richard B.; Evans, Kathryn; Watts, Ben; Bowman, Edward P.; Neuhauser, Steven; Stearns, Timothy; Chuang, Jeffrey H.; Phillip, Vivek M.; Jessen, Katti A.; Jocoy, Emily L.; Bult, Carol J.; Teicher, Beverly A.; Smith, Malcolm A. Share Save
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Spatial proteomics of lung adenocarcinoma mouse models with divergent propensities for metastasis Ramkissoon, Paige; Mitchell-Hutchinson, Naomi; Wells, Julie; Maser, Rick; Stodola, Tim; Hoffmann, Brian; Marchini, Anne; Bechtel, Elaine; Doty, Rosalinda; Bult, Carol J. Share Save
Pediatric Preclinical In Vivo Testing (PIVOT) data portal enables access to 15 years of retrospective treatment study data in support of prospective study design Acevedo, Saul E.; Stearns, Tim M.; Webster, Phillip; Philip, Vivek; Lloyd, Michael W.; Srivastava, Anuj; Neuhauser, Steven; Begley, Dale; Krupke, Debbie; Jocoy, Emily L.; Bult, Carol J.; Chuang, Jeffrey H.; Dean, Dennis A. Share Save
An evaluation of patritumab deruxtecan (HER3-DXd, U3-1402) against pediatric PDX models for hepatoblastoma and rhabdomyosarcoma - A report from the NCI PIVOT Program Kurmasheva, Raushan; Houghton, Peter; Del Pozo, Vanessa; Ghilu, Samson; Nakamura, Ryuichi; Fan, Pang-Dian; Jocoy, Emily; Stearns, Tim; Neuhauser, Steve; Chuang, Jeff; Bult, Carol J.; Teicher, Beverly A.; Smith, Malcolm A. Share Save
GenomeMUSter mouse genetic variation service enables multitrait, multipopulation data integration and analysis Ball, Robyn L.; Bogue, Molly A.; Liang, Hongping; Srivastava, Anuj; Ashbrook, David G.; Lamoureux, Anna; Gerring, Matthew W.; Hatoum, Alexander S.; Kim, Matthew J.; He, Hao; Emerson, Jake; Berger, Alexander K.; Walton, David O.; Sheppard, Keith; El Kassaby, Baha; Castellanos, Francisco; Kunde-Ramamoorthy, Govindarajan; Lu, Lu; Bluis, John; Desai, Sejal; Sundberg, Beth A.; Peltz, Gary; Fang, Zhuoqing; Churchill, Gary A.; Williams, Robert W.; Agrawal, Arpana; Bult, Carol J.; Philip, Vivek M.; Chesler, Elissa J. Share Save
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