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D

Dieter Saur

medicine and health

72H-index
500Paper Count
1.6WCitation Count
Published Papers 200
Publication Date
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Neutrophil-Driven Trogocytosis in PDAC Liver Metastases Restrains Immunosuppressive Macrophage Polarization and Limits Metastatic Progression
errGastroenterology
IF25.1
err2026-05-06
err0
errOAAI
errLarissa Belz; Dominic van den Heuvel; Badr Kilani; Alejandro Martinez-Navarro; Anastassia Akhalkatsi; Markus Joppich; Yinfeng Zhu; Qiongjie Ding; Jinlong Wan; Julia Stermann; Julia Winterhalter; Denise Messerer; Anna Titova; Sanjana Balaji; Santoshi Giri; Luke Eivers; Sebastian Widholz; Stefanie Bärthel; Elisabeth Raatz; Dieter Saur
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errSave
A disease model resource reveals core principles of tissue-specific cancer evolution
errNature
IF48.5
err2026-02-25
err0
errOAAI
errSebastian Mueller; Niklas de Andrade Krätzig; Markus Tschurtschenthaler; Miguel G. Silva; Chiara Thordsen; Riccardo Trozzo; Perrine Simon; Frederic Saab; Thorsten Kaltenbacher; Magdalena Zukowska; Daniele Lucarelli; Rupert Öllinger; Joscha Griger; Nina Groß; Tanja Groll; Jessica Löprich; Antonio E. Zaurito; Linus R. Schömig; Jeroen M. Bugter; Stefanie Bärthel; Chiara Falcomatà; Alexander Strong; Cordelia Brandt; Mulham Najajreh; Aristeidis Papargyriou; Roman Maresch; Katharina A. N. Collins; David Sailer; Christian Schneeweis; Sebastian Burger; Lisa M. Fröhlich; Christine Klement; Alexander Belka; Juan J. Montero; Ute Jungwirth; Maximilian Reichert; Markus Moser; Jens Neumann; George Vassiliou; Juan Cadiñanos; Ignacio Varela; Carsten Marr; Daniel F. Alonso; Pier-Luigi Lollini; Jean Zhao; Louis Chesler; Clare M. Isacke; Angela Riedel; Christian J. Braun; Martin L. Sos; Filippo Beleggia; Hans C. Reinhardt; Monica Musteanu; Mariano Barbacid; Michael Quante; Marc Schmidt-Supprian; Günter Schneider; Simon Clare; Trevor D. Lawley; Gordon Dougan; Katja Steiger; Nathalie Conte; Allan Bradley; Lena Rad; Dieter Saur; Roland Rad
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errSave
A translational colorectal cancer organoid biobank mirrors patients’ tumor histology, molecular profiles, and treatment responses
errJournal of Experimental & Clinical Cancer Research
IF12.8
err2026-02-25
err0
errOAAI
errMoritz Jesinghaus; Miguel Gomes Silva; Antonio Enrico Zaurito; Valentina Brunner; Frederic Saab; Anantharamanan Rajamani; Niklas de Andrade Krätzig; Nicholas Bodenstein; Rémi Guillemant; Junika Pohl; Maxime Schmitt; Rupert Öllinger; Federico Fusco; Julius Shakhtour; Peter Klare; Klaus-Peter Janssen; Sebastian Foersch; Katja Steiger; Roland Rad; Nicole Pfarr; Dieter Saur; Markus Tschurtschenthaler
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errSave
QuiCAT: a scalable and flexible framework for mapping synthetic sequences
errBIOINFORMATICS
IF5.4
err2025-12-01
err0
errOAAI
errLucarelli, Daniele; Kos, Tina; Shull, Caylie; Jimenez, Sara; Oellinger, Rupert; Rad, Roland; Saur, Dieter; Theis, Fabian J.
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errSave
Targeting Mutual Dependence of Phosphatidylinositol-3-Kinase α/δ and Small Ubiquitin-Like Modifier Signaling in Pancreatic Cancer
errGastroenterology
IF25.1
err2025-10-27
err0
errOAAI
errHazal Köse; Christian Schneeweis; Philipp Putze; Constanza Tapia Contreras; Laura Ferreiro; Leonie Witte; Ilaria Deidda; Frederik Herzberg; Sophie Ebert; Juraj Jakubik; Leoni Moldaner; Jovan Todorovic; Isabelle Träger; Chuanbing Zang; Uta M. Demel; Elisabeth Hessmann; Marieluise Kirchner; Simone Rhein; Jens Hoffmann; Zuzana Tatarova; Michael Ghadimi; Dieter Saur; Kai Kappert; Philipp Mertins; Günter Schneider; Ulrich Keller; Matthias Wirth
errShare
errSave
Sensory neurons drive pancreatic cancer progression through glutamatergic neuron-cancer pseudo-synapses
errCancer Cell
IF44.5
err2025-09-25
err0
PREAI
errLei Ren; Chunfeng Liu; Kaan Çifcibaşı; Markus Ballmann; Gerhard Rammes; Carmen Mota Reyes; Sergey Tokalov; Andreas Klingl; Jennifer Grünert; Keshav Goyal; Peter H. Neckel; Ulrich Mattheus; Benjamin Schoeps; Saliha Elif Yıldızhan; Osman Ugur Sezerman; Nedim Can Cevik; Elif Arik Sever; Didem Karakas; Okan Safak; Katja Steiger; Alexander Muckenhuber; Kıvanç Görgülü; Zongyao Chen; JingCheng Zhang; Linhan Ye; Mohammed Inayatullah Maula Ali; Vijay K. Tiwari; Nataliya Romanyuk; Florian Giesert; Dieter Saur; Roland Rad; Roland M. Schmid; Hana Algül; Achim Krüger; Helmut Friess; Güralp O. Ceyhan; Rouzanna Istvanffy; Ihsan Ekin Demir
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errSave
Activation of RAS/MEK/ERK signalling drives biliary differentiation in primary liver cancer
errGUT
IF25.8
err2025-05-12
err0
PREAI
errRoesner, Thomas; Rupp, Carina; Lechler, Christian; Bauer, Ulrike; Manmadhan, Saumya Sukumary; Bernatik, Sophia; Delugre, Fabian; Ihli, Franziska; Derowski, Tanja; Joers, Simone; Kohnke-Ertel, Birgit; Einwaechter, Henrik; Pfarr, Nicole; Steiger, Katja; Mogler, Carolin; Reichert, Maximilian; Saur, Dieter; Becker, Diana; Marquardt, Jens U.; Oellinger, Rupert; Engleitner, Thomas; Rad, Roland; Schmid, Roland M.; Ehmer, Ursula
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errSave
Hexokinase2-engineered T cells display increased anti-tumor function
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2025-03-20
err0
errOAAI
errZur, Raphaelle Toledano; Zurinam, Shiran Didi; Radman, Maria; Balouka, Elia Funaro; Borodianskiy-Shteinberg, Tatiana; Saur, Dieter
errShare
errSave
Pancreatic cancer cells infiltrate nerves through TGFbeta1-driven perineural epithelial-to-mesenchymal-like transdifferentiation
errNEOPLASIA
IF7.7
err2025-02-01
err0
errOAAI
errKrauss, Theresa; Guercinar, Ibrahim Halil; Bourquain, Ulrike; Hieber, Maren; Krohmer, Evelyn N.; Wu, Nan; Tokalov, Sergey; Goess, Ruediger; Reyes, Carmen Mota; Saur, Dieter; Friess, Helmut; Ceyhan, Gueralp O.; Demir, Ihsan Ekin; Safak, Okan
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errSave
Hyperreactive B cells instruct their elimination by T cells to curb autoinflammation and lymphomagenesis
errIMMUNITY
IF26.3
err2025-01-01
err0
errOAAI
errDiehl, Carina; Soberon, Valeria; Bayguen, Seren; Chu, Yuanyuan; Mandelbaum, Jonathan; Kraus, Laura; Engleitner, Thomas; Rudelius, Martina; Fangazio, Marco; Daniel, Christoph; Bortoluzzi, Sabrina; Helmrath, Sabine; Singroul, Pankaj; Goelling, Vanessa; Barrios, Francisco Osorio; Seyhan, Goenul; Osswald, Lena; Kober-Hasslacher, Maike; Zeng, Theodor; Oellinger, Rupert; Afzali, Ali M.; Korn, Thomas; Honarpisheh, Mohsen; Lech, Maciej; Ul Ain, Qurrat; Pircher, Joachim; Imsirovic, Vanna; Jeleneic, Vedrana; Wensveen, Felix M.; Passerini, Verena; Baerthel, Stefanie; Dominguez-Sola, David; Ollinger, Rupert; Saur, Dieter; Steiger, Katja; Rad, Roland; Pasqualucci, Laura; Weigert, Oliver; Schmidt-Supprian, Marc
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errSave
Heterogeneity-driven phenotypic plasticity and treatment response in branched-organoid models of pancreatic ductal adenocarcinoma
errNATURE BIOMEDICAL ENGINEERING
IF26.6
err2024-12-10
err0
errOAAI
errPapargyriou, Aristeidis; Najajreh, Mulham; Cook, David P.; Maurer, Carlo H.; Baerthel, Stefanie; Messal, Hendrik A.; Ravichandran, Sakthi K.; Richter, Till; Knolle, Moritz; Metzler, Thomas; Shastri, Akul R.; Oellinger, Rupert; Jasper, Jacob; Schmidleitner, Laura; Wang, Surui; Schneeweis, Christian; Ishikawa-Ankerhold, Hellen; Engleitner, Thomas; Mataite, Laura; Semina, Mariia; Trabulssi, Hussein; Lange, Sebastian; Ravichandra, Aashreya; Schuster, Maximilian; Mueller, Sebastian; Peschke, Katja; Schaefer, Arlett; Dobiasch, Sophie; Combs, Stephanie E.; Schmid, Roland M.; Bausch, Andreas R.; Braren, Rickmer; Heid, Irina; Scheel, Christina H.; Schneider, Guenter; Zeigerer, Anja; Luecken, Malte D.; Steiger, Katja; Kaissis, Georgios; van Rheenen, Jacco; Theis, Fabian J.; Saur, Dieter; Rad, Roland; Reichert, Maximilian
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errSave
Vasoactive intestinal peptide promotes secretory differentiation and mitigates radiation-induced intestinal injury
errSTEM CELL RESEARCH & THERAPY
IF7.3
err2024-10-08
err0
errOAAI
errAgibalova, Tatiana; Hempel, Anneke; Maurer, H. Carlo; Ragab, Mohab; Ermolova, Anastasia; Wieland, Jessica; de Melo, Caroline Waldherr Avila; Heindl, Fabian; Giller, Maximilian; Fischer, Julius Clemens; Tschurtschenthaler, Markus; Kohnke-Ertel, Birgit; Oellinger, Rupert; Steiger, Katja; Demir, Ihsan Ekin; Saur, Dieter; Quante, Michael; Schmid, Roland M.; Middelhoff, Moritz
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errSave
A porcine model of pancreatic ductal adenocarcinoma for human scale translational cancer research
errCANCER RESEARCH
IF16.6
err2024-09-15
err0
PREAI
errSanguesa, Laura Beltran; Kalla, Daniela; Steiger, Katja; Saur, Dieter; Flisikowski, Krzysztof; Schnieke, Angelika; Flisikowska, Tatiana
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errSave
KRASG12C-inhibitor-based combination therapies for pancreatic cancer: insights from drug screening
errMOLECULAR ONCOLOGY
IF4.5
err2024-09-10
err0
errOAAI
errContreras, Constanza Tapia; Falke, Jonas Dominik; Seifert, Dana-Magdalena; Schneider, Carolin; Krauss, Lukas; Fang, Xin; Mueller, Denise; Demirdizen, Engin; Spitzner, Melanie; De Oliveira, Tiago; Schneeweis, Christian; Gaedcke, Jochen; Kaulfuss, Silke; Mirzakhani, Kimia; Wollnik, Bernd; Conrads, Karly; Beissbarth, Tim; Salinas, Gabriela; Huegel, Jonas; Beyer, Nils; Rheinlander, Sophia; Sax, Ulrich; Wirth, Matthias; Conradi, Lena-Christin; Reichert, Maximilian; Ellenrieder, Volker; Strobel, Philipp; Ghadimi, Michael; Grade, Marian; Saur, Dieter; Hessmann, Elisabeth; Schneider, Gunter
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errSave
ZEB1-mediated fibroblast polarization controls inflammation and sensitivity to immunotherapy in colorectal cancer
errEMBO REPORTS
IF6.2
err2024-06-27
err0
errOAAI
errMenche, Constantin; Schuhwerk, Harald; Armstark, Isabell; Gupta, Pooja; Fuchs, Kathrin; van Roey, Ruthger; Mosa, Mohammed H.; Hartebrodt, Anne; Hajjaj, Yussuf; Ezquerra, Ana Clavel; Selvaraju, Manoj K.; Geppert, Carol, I; Baerthel, Stefanie; Saur, Dieter; Greten, Florian R.; Brabletz, Simone; Blumenthal, David B.; Weigert, Andreas; Brabletz, Thomas; Farin, Henner F.; Stemmler, Marc P.
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errSave
A Novel AMPK Inhibitor Sensitizes Pancreatic Cancer Cells to Ferroptosis Induction
errADVANCED SCIENCE
IF14.1
err2024-06-17
err2
errOAAI
errSchneider, Carolin; Hilbert, Jorina; Genevaux, Franziska; Hoefer, Stefanie; Krauss, Lukas; Schicktanz, Felix; Contreras, Constanza Tapia; Jansari, Shaishavi; Papargyriou, Aristeidis; Richter, Thorsten; Alfayomy, Abdallah M.; Falcomata, Chiara; Schneeweis, Christian; Orben, Felix; Oellinger, Ruppert; Wegwitz, Florian; Boshnakovska, Angela; Rehling, Peter; Mueller, Denise; Stroebel, Philipp; Ellenrieder, Volker; Conradi, Lena; Hessmann, Elisabeth; Ghadimi, Michael; Grade, Marian; Wirth, Matthias; Steiger, Katja; Rad, Roland; Kuster, Bernhard; Sippl, Wolfgang; Reichert, Maximilian; Saur, Dieter; Schneider, Guenter
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errSave
The Janus kinase 1 is critical for pancreatic cancer initiation and progression
errCELL REPORTS
IF6.9
err2024-05-01
err0
errOAAI
errShrestha, Hridaya; Radler, Patrick D.; Dennaoui, Rayane; Wicker, Madison N.; Rajbhandari, Nirakar; Sun, Yunguang; Peck, Amy R.; Vistisen, Kerry; Triplett, Aleata A.; Beydoun, Rafic; Sterneck, Esta; Saur, Dieter; Rui, Hallgeir; Wagner, Kay-Uwe
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errSave
Multimodal spatial transcriptomics uncover distinct tumor microenvironment states and cell-cell communication networks in molecular pancreatic cancer subtypes
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errBaerthel, Stefanie; Falcomata, Chiara; Goelling, Vanessa; Lucarelli, Daniele; Gindra, Rushin; Schmitt, Constantin; Swietlik, Jonathan; Meissner, Felix; Schmidt-Supprian, Marc; Saur, Dieter
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errSave
Double-targeting of pancreatic ductal adenocarcinoma (PDAC): Unveiling the potent combination of NMS-873 and BAY-876
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errEppinger, Emily Rita; Schneeweis, Christian; Saur, Dieter
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errSave
Novel Tumor Organoid-Based Mouse Model to Study Image Guided Radiation Therapy of Rectal Cancer After Noninvasive and Precise Endoscopic Implantation
errINTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
IF6.5
err2024-03-01
err4
errOAAI
errFelchle, Hannah; Brunner, Valentina; Groll, Tanja; Walther, Caroline N.; Nefzger, Sophie M.; Zaurito, Antonio E.; Silva, Miguel G.; Gissibl, Julia; Topping, Geoffrey J.; Rotgerink, Laura Lansink; Saur, Dieter; Steiger, Katja; Combs, Stephanie E.; Tschurtschenthaler, Markus; Fischer, Julius C.
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Research Directions

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