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Dynamic modelling of EWS::FLI1 fluctuations reveals molecular determinants of phenotypic tumor plasticity and prognosis in Ewing sarcoma Suresh, Veveeyan; Hafemeister, Christoph; Grissenberger, Sarah; Sturtzel, Caterina; Aranaz, Florencia Cidre; Grunewald, Thomas; Sastre, Ana; Alonso, Javier; Distel, Martin; Halbritter, Florian; Kovar, Heinrich; Fock, Valerie Share Save
In vitro modeling of pediatric solid tumor lung metastases Zylka, Martha; Hafemeister, Christoph; Watzke, Lukas; Mann, Ulrike; Surdez, Didier; Sweet-Cordero, E. Alejandro; Liegl-Atzwanger, Bernadette; Dettmer, Matthias; Farlik, Matthias; Halbritter, Florian; Metzelder, Martin; Kovar, Heinrich; Radic-Sarikas, Branka Share Save
Dedifferentiation unveils origin of Ewing sarcoma Kapoor, Utkarsh; Hafemeister, Christoph; Shaw, Lisa; Muelbacher, Karin; Moldaschl, Julia; Egger, Dominik; Toegel, Stefan; Kasper, Cornelia; Farlik, Matthias; Halbritter, Florian; Kovar, Heinrich Share Save
ITCC-P4, a preclinical proof-of-concept drug testing platform as a tool for pharmacological screening in pediatric tumor models Indersie, Emilie; Branchereau, Sophie; Fresneau, Brice; Chardot, Christophe; Surdez, Didier; Saint-Charles, Alexandra; da Costa, Maria Eugenia Marques; Carcaboso, Angel M.; Scotlandi, Katia; Moro, Massimo; Kovar, Heinrich; Klusmann, Jan-Henning; Debatin, Klaus-Michael; Bomken, Simon; Chesler, Louis; Jones, Chris; Schafer, Beat; Wachtel, Marco; Gojo, Johannes; Berger, Walter; Guttke, Christina; Hattersley, Maureen; Colland, Frederic; Strougo, Ashley; Gurgen, Dennis; Hoffmann, Jens; Schueler, Julia; Aviles, Pablo M.; Guillen, Maria Jose; Federico, Aniello; Gopisetty, Apurva; Wierzbinska, Justyna Anna; Schlicker, Andreas; Colombetti, Sara; Heidenreich, Olaf; Iradier, Fatima; Huebener, Nicole; Jager, Natalie; Koster, Jan; Kool, Marcel; Schleiermacher, Gudrun; Molenaar, Jan J.; Geoerger, Birgit; Shields, David J.; Caron, Hubert N.; Stancato, Louis F.; Pfister, Stefan M.; Vassal, Gilles; Rief, Eva-Maria; Deas, Olivier Share Save
The ITCC-P4 sustainable platform of fully characterized PDXs supports the preclinical proof-of-concept drug testing of high-risk pediatric tumor models Federico, Aniello; Gopisetty, Apurva; Surdez, Didier; Iddir, Yasmine; Saint-Charles, Alexandra; Wierzbinska, Justyna; Schlicker, Andreas; Volckmann, Richard; Zwijnenburg, Danny; Colombetti, Sara; Heidenreich, Olaf; Iradier, Fatima; Kovar, Heinrich; Klusmann, Jan-Henning; Debatin, Klaus-Michael; Bomken, Simon; Guttke, Christina; Hattersley, Maureen M.; Colland, Frederic; Strougo, Ashley; Guillen, Maria Jose; Chesler, Louis; Jones, Chris; da Costa, Maria Eugenia Marques; Scotlandi, Katia; Moro, Massimo; Schafer, Beat; Wachtel, Marco; Gojo, Johannes; Berger, Walter; Carcaboso, Angel Montero; Gurgen, Dennis; Hoffmann, Jens; Indersie, Emilie; Cairo, Stefano; Schueler, Julia; Huebener, Nicole; Schulte, Johannes H.; Molenaar, Jan J.; Geoerger, Birgit; Shields, David J.; Caron, Hubert N.; Vassal, Gilles; Stancato, Lou F.; Pfister, Stefan M.; Jager, Natalie; Koster, Jan; Kool, Marcel; Schleiermacher, Gudrun Share Save
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ITCC-P4: Genomic profiling and analyses of pediatric patient tumor and patient-derived xenograft (PDX) models for high throughput in vivo testing Gopisetty, Apurva; Federico, Aniello; Surdez, Didier; Iddir, Yasmine; Zaidi, Sakina; Saint-Charles, Alexandra; Waterfall, Joshua; Saberi-Ansari, Elnaz; Wierzbinska, Justyna; Schlicker, Andreas; Mack, Norman; Schwalm, Benjamin; Previti, Christopher; Weiser, Lena; Buchhalter, Ivo; Bottcher, Anna-Lisa; Sill, Martin; Autry, Robert; Estermann, Frank; Jones, David; Volckmann, Richard; Zwijnenburg, Danny; Eggert, Angelika; Heidenreich, Olaf; Iradier, Fatima; Jeremias, Irmela; Kovar, Heinrich; Klusmann, Jan-Henning; Debatin, Klaus-Michael; Bomken, Simon; Hamerlik, Petra; Hattersley, Maureen; Witt, Olaf; Chesler, Louis; Mackay, Alan; Gojo, Johannes; Cairo, Stefano; Schueler, Julia; Schulte, Johannes; Geoerger, Birgit; Molenaar, Jan J.; Shields, David J.; Caron, Hubert N.; Vassal, Gilles; Stancato, Louis F.; Pfister, Stefan M.; Jaeger, Natalie; Koster, Jan; Kool, Marcel; Schleiermacher, Gudrun Share Save
High-content drug screening in zebrafish xenografts reveals high efficacy of dual MCL-1/BCL-XL inhibition against Ewing sarcoma Grissenberger, Sarah; Sturtzel, Caterina; Wenninger-Weinzierl, Andrea; Radic-Sarikas, Branka; Scheuringer, Eva; Bierbaumer, Lisa; Etienne, Vesnie; Nemati, Fariba; Pascoal, Susana; Toetzl, Marcus; Tomazou, Eleni M.; Metzelder, Martin; Putz, Eva M.; Decaudin, Didier; Delattre, Olivier; Surdez, Didier; Kovar, Heinrich; Halbritter, Florian; Distel, Martin Share Save
An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma Shulman, David S.; Whittle, Sarah B.; Surdez, Didier; Bailey, Kelly M.; de Alava, Enrique; Yustein, Jason T.; Shlien, Adam; Hayashi, Masanori; Bishop, Alexander J. R.; Crompton, Brian D.; DuBois, Steven G.; Shukla, Neerav; Leavey, Patrick J.; Lessnick, Stephen L.; Kovar, Heinrich; Delattre, Olivier; Gruenewald, Thomas G. P.; Antonescu, Cristina R.; Roberts, Ryan D.; Toretsky, Jeffrey A.; Tirode, Franck; Gorlick, Richard; Janeway, Katherine A.; Reed, Damon; Lawlor, Elizabeth R.; Grohar, Patrick J. Share Save
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Ewing Sarcoma-Diagnosis, Treatment, Clinical Challenges and Future Perspectives Zoellner, Stefan K.; Amatruda, James E.; Bauer, Sebastian; Collaud, Stephane; de Alava, Enrique; DuBois, Steven G.; Hardes, Jendrik; Hartmann, Wolfgang; Kovar, Heinrich; Metzler, Markus; Shulman, David S.; Streitbuerger, Arne; Timmermann, Beate; Toretsky, Jeffrey A.; Uhlenbruch, Yasmin; Vieth, Volker; Gruenewald, Thomas G. P.; Dirksen, Uta Share Save
YAP/TAZ inhibition reduces metastatic potential of Ewing sarcoma cells Bierbaumer, Lisa; Katschnig, Anna M.; Radic-Sarikas, Branka; Kauer, Maximilian O.; Petro, Jeffrey A.; Hoegler, Sandra; Gurnhofer, Elisabeth; Pedot, Gloria; Schafer, Beat W.; Schwentner, Raphaela; Muehlbacher, Karin; Kromp, Florian; Aryee, Dave N. T.; Kenner, Lukas; Uren, Aykut; Kovar, Heinrich Share Save
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ETS Proteins Bind with Glucocorticoid Receptors: Relevance for Treatment of Ewing Sarcoma Srivastava, Swati; Nataraj, Nishanth Belugali; Sekar, Arunachalam; Ghosh, Soma; Bornstein, Chamutal; Drago-Garcia, Diana; Roth, Lee; Romaniello, Donatella; Marrocco, Ilaria; David, Eyal; Gilad, Yuval; Lauriola, Mattia; Rotkopf, Ron; Kimchi, Adi; Haga, Yuya; Tsutsumi, Yasuo; Mirabeau, Olivier; Surdez, Didier; Zinovyev, Andrei; Delattre, Olivier; Kovar, Heinrich; Amit, Ido; Yarden, Yosef Share Save
RETRACTION: Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation (Retraction of Vol 7, art no E2419, 2016) Javaheri, Tahereh; Kazemi, Zahra; Pencik, Jan; Pham, Ha T. T.; Kauer, Maximilian; Noorizadeh, Rahil; Sax, Barbara; Nivarthi, Harini; Schlederer, Michaela; Maurer, Barbara; Hofbauer, Maximillian; Aryee, Dave N. T.; Wiedner, Marc; Tomazou, EleniM.; Logan, Malcolm; Hartmann, Christine; Tuckermann, Jan P.; Kenner, Lukas; Mikula, Mario; Dolznig, Helmut; Uren, Aykut; Richter, Guenther H.; Grebien, Florian; Kovar, Heinrich; Moriggl, Richard Share Save
EWS-FLI1 modulated alternative splicing of ARID1A reveals novel oncogenic function through the BAF complex Selvanathan, Saravana P.; Graham, Garrett T.; Grego, Alexander R.; Baker, Tabari M.; Hogg, J. Robert; Simpson, Mark; Batish, Mona; Crompton, Brian; Stegmaier, Kimberly; Tomazou, Eleni M.; Kovar, Heinrich; Uren, Aykut; Toretsky, Jeffrey A. Share Save
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