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US Food and Drug Administration approvals for pediatric cancer indications using Children's Oncology Group-associated trials data Macy, Margaret E.; Fox, Elizabeth; Weigel, Brenda J.; Foster, Jennifer H.; Beeles, Thalia; Sullivan, Mary Beth; Towcimak, Nicole; Gore, Lia; Smith, Malcolm A.; Hawkins, Douglas S. Share Save
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The impact of focused federal initiatives on pediatric cancer research Jagu, Subhashini; Smith, Malcolm A.; Seibel, Nita L.; Tonorezos, Emily S.; Widemann, Brigitte C.; Gibbons, Holly A.; Holohan, Mary K.; Ababiya, Ziky A.; Guidry Auvil, Jaime M.; Lowy, Douglas R.; Doroshow, James H.; Lubenow, Anne E.; Reaman, Gregory H. Share Save
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Adaptive evolution of drug responses to monotherapy ONC201 in PDOX models of pediatric brain tumors Chen, Jinnan; Abdallah, Aalaa; Palacios, Milagros Suarez; Zhai, Xin; Hang, Zilu; Jiang, Tongchao; Ciolak, Emily; Hoesley, Aria; Mei, Yiming; Bellis, James; Wadhwani, Nitin; Lenzen, Alicia; Kwon, Jee Young; Neuhauser, Steve; Stearns, Tim; Chuang, Jeff; Jocoy, Emily; Bult, Carol; Teicher, Beverly; Smith, Malcolm; Li, Xiaonan; Du, Yuchen Share Save
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Childhood cancer data initiative: expanded access to tumor molecular profiling for children, adolescents, and young adults Flores-Toro, Joseph; Jagu, Subhashini; Smith, Malcolm; Shern, John; Hawkins, Douglas S.; Mardis, Elaine R.; Rudzinski, Erin; Alonzo, Todd A.; Beeles, Thalia; Ramirez, Nilsa; Thomas, Diana L.; Cottrell, Catherine E.; Parbhoo, Kareesma; Janeway, Katherine A.; Leary, Sarah; Fouladi, Maryam; Oberoi, Sapna; Venkatramani, Rajkumar; Irwin, Meredith; Laetsch, Theodore W.; Chen, Kenneth S.; Bailey, Kelly; Davis, Jessica L.; Sullivan, Mary Beth; Boja, Emily; Lowy, Douglas; Guidry Auvil, Jaime M.; Wideman, Brigitte; Kibbe, Warren; Doroshow, James; Reaman, Gregory H. Share Save
The CD123 antibody-drug conjugate pivekimab sunirine exerts profound activity in preclinical models of pediatric acute lymphoblastic leukemia Watts, Ben; Smith, Christopher M.; Evans, Kathryn; Gifford, Andrew J.; Mohamed, Sara M. A.; Erickson, Stephen W.; Earley, Eric J.; Neuhauser, Steven; Stearns, Timothy M.; Philip, Vivek M.; Chuang, Jeffrey H.; Zweidler-McKay, Patrick A.; Lakshmikanthan, Sribalaji; Jocoy, Emily L.; Bult, Carol J.; Teicher, Beverly A.; Smith, Malcolm A. Share Save
Lessons learned from 20 years of preclinical testing in pediatric cancers Smith, Malcolm A.; Houghton, Peter J.; Lock, Richard B.; Maris, John M.; Gorlick, Richard; Kurmasheva, Raushan T.; Li, Xiao-Nan; Teicher, Beverly A.; Chuang, Jeffrey H.; Cruz, Filemon S. Dela; Dyer, Michael A.; Kung, Andrew L.; Lloyd, Michael W.; Mosse, Yael P.; Stearns, Timothy M.; Stewart, Elizabeth A.; Bult, Carol J.; Erickson, Stephen W. Share Save
The novel ATR inhibitor elimusertib is efficacious as monotherapy and in combination with radiation in pdox models of pediatric high-grade glioma Palacios, M. Suarez; Du, Y.; Xiao, S.; Abdallah, A.; Zhai, X.; Ciolak, E.; Huang, Z.; Kalapurakal, J.; Wadhwani, N.; Lenzen, A.; Kwon, J. Y.; Neuhauser, S.; Stearns, T.; Chuang, J.; Jocoy, E. L.; Bult, C.; Teicher, B.; Smith, M. A.; Li, X. N. Share Save
Whole genome and reverse protein phase array landscapes of patient derived osteosarcoma xenograft models Wu, Chia-Chin; Huang, Licai; Zhang, Zhongting; Ju, Zhenlin; Song, Xingzhi; Kolb, E. Anders; Zhang, Wendong; Gill, Jonathan; Ha, Min; Smith, Malcolm A.; Houghton, Peter; Morton, Christopher L.; Kurmasheva, Raushan; Maris, John; Mosse, Yael; Lu, Yiling; Gorlick, Richard; Futreal, P. Andrew; Beird, Hannah C. Share Save
Paediatric strategy forum for medicinal product development of PI3-K, mTOR, AKT and GSK3β inhibitors in children and adolescents with cancer Pearson, Andrew D. J.; DuBois, Steven G.; Macy, Margaret E.; de Rojas, Teresa; Donoghue, Martha; Weiner, Susan; Knoderer, Holly; Bernardi, Ronald; Buenger, Vickie; Canaud, Guillaume; Cantley, Lewis; Chung, John; Fox, Elizabeth; Friend, John; Glade-Bender, Julia; Gorbatchevsky, Igor; Gore, Lia; Gupta, Abha; Hawkins, Douglas S.; Juric, Dejan; Lang, Leigh Anna; Leach, Danielle; Liaw, Danny; Lesa, Giovanni; Ligas, Franca; Lindberg, Gavin; Lindberg, Wendy; Ludwinski, Donna; Marshall, Lynley; Mazar, Andrew; McDonough, Joe; Nysom, Karsten; Urs, Christopher O.; Pappo, Alberto; Parsons, D. William; Rosenfeld, Amy; Scobie, Nicole; Smith, Malcolm; Taylor, Danielle; Weigel, Brenda; Weinstein, Amy; Karres, Dominik; Vassal, Gilles Share Save
In vivo efficacy of anti-B7-H3 antibody-drug conjugate (ADC) ifinatamab deruxtecan (I-DXd; DS-7300): An update from the Pediatric Preclinical In Vivo Testing (PIVOT) Program Gorlick, Richard; Gill, Jonathan; Zhang, Wendong; Mosse, Yael; Maris, John; Groff, David; Smith, Malcolm; Teicher, Beverly; Neuhauser, Steve; Stearns, Tim; Philip, Vivek; Jocoy, Emily; Chuang, Jeff; Bult, Carol J.; Hasegawa, Jun; Qian, Xiaozhong; Houghton, Peter; Kurmasheva, Raushan Share Save
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The ROR1 antibody-drug conjugate, MK-2140, enhances the efficacy of established drugs in preclinical models of pediatric acute lymphoblastic leukemia Lock, Richard B.; Evans, Kathryn; Watts, Ben; Bowman, Edward P.; Neuhauser, Steven; Stearns, Timothy; Chuang, Jeffrey H.; Phillip, Vivek M.; Jessen, Katti A.; Jocoy, Emily L.; Bult, Carol J.; Teicher, Beverly A.; Smith, Malcolm A. Share Save
An evaluation of patritumab deruxtecan (HER3-DXd, U3-1402) against pediatric PDX models for hepatoblastoma and rhabdomyosarcoma - A report from the NCI PIVOT Program Kurmasheva, Raushan; Houghton, Peter; Del Pozo, Vanessa; Ghilu, Samson; Nakamura, Ryuichi; Fan, Pang-Dian; Jocoy, Emily; Stearns, Tim; Neuhauser, Steve; Chuang, Jeff; Bult, Carol J.; Teicher, Beverly A.; Smith, Malcolm A. Share Save
The menin inhibitor VTP-50469 enhances the in vivo efficacy of established drugs against preclinical models of aggressive infant MLL-r acute lymphoblastic leukemia Lock, Richard B.; Evans, Kathryn; Gawan-Taylor, Sophia; Watts, Ben; Stearns, Timothy; Earley, Eric J.; Jocoy, Emily L.; Bult, Carol J.; Teicher, Beverly A.; McGeehan, Gerard M.; Smith, Malcolm A. Share Save
Paediatric Strategy Forum for medicinal product development of DNA damage response pathway inhibitors in children and adolescents with cancer: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration Pearson, Andrew D. J.; Federico, Sara; Gatz, Susanne A.; Ortiz, Michael; Lesa, Giovanni; Scobie, Nicole; Gounaris, Ioannis; Weiner, Susan L.; Weigei, Brenda; Unger, T. J.; Stewart, Elizabeth; Smith, Malcolm; Slotkin, Emily K.; Reaman, Gregory; Pappo, Alberto; Nysom, Karsten; Norga, Koen; McDonough, Joe; V. Marshall, Lynley; Ludwinski, Donna; Ligas, Franca; Karres, Dominik; Kool, Marcel; Horner, Thierry J.; Henssen, Anton; Heenen, Delphine; Hawkins, Douglas S.; Gore, Lia; Bender, Julia Glade; Galluzzo, Sara; Fox, Elizabeth; de Rojas, Teresa; Davies, Barry R.; Chakrabarti, Jayeta; Carmichael, Juliet; Bradford, Diana; Blanc, Patricia; Bernardi, Ronald; Benchetrit, Sylvie; Akindele, Korede; Vassal, Gilles Share Save
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