Paul J. Hertzog - Publications, H-index & Citations

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Paul J. Hertzog

Hudson Institute of Medical Research

73H-index

415Paper Count

2.7WCitation Count

Published Papers 171

Publication Date

Loss of cellular RNA homeostasis contributes to MDA5 activation during virus infection

Nature Immunology

IF27.6

2026-08-11

OAAI

Natália G. Sampaio; Tanja Davis; Linden J. Gearing; Antonio G. Dias Junior; Lise Chauveau; Georgie Wray-McCann; Valerie Odon; Vladyslava Liudkovska; Alexandra L. McAllan; Chiara Cursi; Alice Mayer; Madara Ratnadiwakara; Minna-Liisa Änkö; Maciej Cieśla; Paul J. Hertzog; Jan Rehwinkel

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Striking the right balance with type I interferon signalling in cancer

Nature Reviews Cancer

IF66.8

2026-03-01

PREAI

Chadwick, Thomas B.; So, Joan; Hertzog, Paul J.; Haynes, Nicole M.; Parker, Belinda S.

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2′-O-Methyl-guanosine RNA fragments antagonize TLR7 and TLR8 to limit autoimmunity

Nature Immunology

IF27.6

2026-02-10

OAAI

Arwaf S. Alharbi; Sunil Sapkota; Zhikuan Zhang; Ruitao Jin; Erandi Rupasinghe; W. Samantha N. Jayasekara; Dingyi Yu; Mary Speir; Lorna Wilkinson-White; Liza Cubeddu; Julia I. Ellyard; Refaya Rezwan; Daniel S. Wenholz; Alexandra L. McAllan; Rui Gao; Le Ying; Rasan M. Sathiqu; Hani Hosseini Far; Josiah Bones; Sitong He; Marina R. Alexander; Kim A. Lennox; Paul J. Hertzog; Claudia A. Nold-Petry; Cameron R. Stewart; Carola G. Vinuesa; Mark A. Behlke; Umeharu Ohto; Olivier F. Laczka; Roland Gamsjaeger; Ben Corry; Toshiyuki Shimizu; Michael P. Gantier

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Interferon-epsilon, an estrogen-induced type I interferon, is uniquely exploited by Neisseria gonorrhoeae via effects on sialic acid metabolism

Cell Host & Microbe

IF18.7

2025-06-09

OAAI

Evelyn A. Kurt-Jones; Sunita Gulati; Michael King; Rosane B. de Oliveira; Peter A. Rice; Bo Zheng; Jutamas Shaughnessy; Jennifer L. Edwards; Paul J. Hertzog; Sanjay Ram; Douglas T. Golenbock

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Type I interferon signaling controls the early hematopoietic expansion in response to R-glucan

ISCIENCE

IF4.1

2025-05-01

OAAI

Xu, Yangsong; Lee, Man K. S.; Weerd, Nicole A. de; Fu, Ziyue; Veiga, Camilla Bertuzzo; Dragoljevic, Dragana; Sviridov, Dmitri; Hertzog, Paul J.; Fleetwood, Andrew J.; Murphy, Andrew J.

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NLRP3 deficiency abrogates silica-induced neutrophil infiltration, pulmonary damage and fibrosis

RESPIRATORY RESEARCH

IF5

2025-03-21

OAAI

Lam, Maggie; Barry, Kristian T.; Hodges, Christopher J.; Harpur, Christopher M.; Ong, James D. H.; Rosli, Sarah; West, Alison C.; Dousha, Lovisa; Hertzog, Paul J.; Mansell, Ashley

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Interferon epsilon is produced in the testis and protects the male reproductive tract against virus infection, inflammation and damage

PLOS PATHOGENS

IF4.9

2024-12-02

OAAI

Wijayarathna, Rukmali; de Geus, Eveline D.; Genovese, Rosemary; Gearing, Linden J.; Wray-McCann, Georgie; Sreenivasan, Rajini; Hasan, Hiba; Fijak, Monika; Stanton, Peter; Fietz, Daniela; Pilatz, Adrian; Schuppe, Hans-Christian; Tate, Michelle D.; Hertzog, Paul J.; Hedger, Mark P.

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A STAT3-STING-IFN axis controls the metastatic spread of small cell lung cancer

NATURE IMMUNOLOGY

IF27.6

2024-11-21

PREAI

Guanizo, Aleks C.; Luong, Quinton; Jayasekara, W. Samantha N.; de Geus, Eveline D.; Inampudi, Chaitanya; Xue, Vincent Senyang; Chen, Jasmine; de Weerd, Nicole A.; Matthews, Antony Y.; Gantier, Michael P.; Balic, Jesse J.; Arulananda, Surein; Garama, Daniel J.; Hertzog, Paul J.; Ganju, Vinod; Watkins, D. Neil; Cain, Jason E.; Gough, Daniel J.

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Expression of Interferon Epsilon in Mucosal Epithelium is Regulated by Elf3

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2024-07-08

PREAI

Fung, Ka Yee; de Geus, Eveline D.; Ying, Le; Cumming, Helen; Bourke, Nollaig; Foster, Samuel C.; Hertzog, Paul J.

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Interferon-epsilon is a novel regulator of NK cell responses in the uterus

EMBO MOLECULAR MEDICINE

IF8.3

2024-01-23

OAAI

Mayall, Jemma R.; Horvat, Jay C.; Mangan, Niamh E.; Chevalier, Anne; McCarthy, Huw; Hampsey, Daniel; Donovan, Chantal; Brown, Alexandra C.; Matthews, Antony Y.; de Weerd, Nicole A.; de Geus, Eveline D.; Starkey, Malcolm R.; Kim, Richard Y.; Daly, Katie; Goggins, Bridie J.; Keely, Simon; Maltby, Steven; Baldwin, Rennay; Foster, Paul S.; Boyle, Michael J.; Tanwar, Pradeep S.; Huntington, Nicholas D.; Hertzog, Paul J.; Hansbro, Philip M.

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Epithelially Restricted Interferon Epsilon Protects Against Colitis

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY

IF7.4

2024-01-01

OAAI

de Geus, Eveline D.; Volaric, Jennifer S.; Matthews, Antony Y.; Mangan, Niamh E.; Chang, Janet; Ooi, Joshua D.; de Weerd, Nicole A.; Giles, Edward M.; Hertzog, Paul J.

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Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon (vol 14, 3513, 2023)

NATURE COMMUNICATIONS

IF15.7

2023-07-20

OAAI

Ryan, Tristram A. J.; Hooftman, Alexander; Rehill, Aisling M.; Johansen, Matt D.; O' Brien, Eoin C.; Toller-Kawahisa, Juliana E.; Wilk, Mieszko M.; Day, Emily A.; Weiss, Hauke J.; Sarvari, Pourya; Vozza, Emilio G.; Schramm, Fabian; Peace, Christian G.; Zotta, Alessia; Miemczyk, Stefan; Nalkurthi, Christina; Hansbro, Nicole G.; McManus, Gavin; O'Doherty, Laura; Gargan, Siobhan; Long, Aideen; Dunne, Jean; Cheallaigh, Cliona Ni; Conlon, Niall; Carty, Michael; Fallon, Padraic G.; Mills, Kingston H. G.; Creagh, Emma M.; O' Donnell, James S.; Hertzog, Paul J.; Hansbro, Philip M.; McLoughlin, Rachel M.; Wygrecka, Malgorzata; Preston, Roger J. S.; Zaslona, Zbigniew; O'Neill, Luke A. J.

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Bacterial clade-specific analysis identifies distinct epithelial responses in inflammatory bowel disease

CELL REPORTS MEDICINE

IF10.6

2023-07-01

OAAI

D'Adamo, Gemma L.; Chonwerawong, Michelle; Gearing, Linden J.; Marcelino, Vanessa R.; Gould, Jodee A.; Rutten, Emily L.; Solari, Sean M.; Khoo, Patricia W. R.; Wilson, Trevor J.; Thomason, Tamblyn; Gulliver, Emily L.; Hertzog, Paul J.; Giles, Edward M.; Forster, Samuel C.

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Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon

NATURE COMMUNICATIONS

IF15.7

2023-06-14

OAAI

Ryan, Tristram A. J.; Hooftman, Alexander; Rehill, Aisling M.; Johansen, Matt D.; O'Brien, Eoin C.; Toller-Kawahisa, Juliana E.; Wilk, Mieszko M.; Day, Emily A.; Weiss, Hauke J.; Sarvari, Pourya; Vozza, Emilio G.; Schramm, Fabian; Peace, Christian G.; Zotta, Alessia; Miemczyk, Stefan; Nalkurthi, Christina; Hansbro, Nicole G.; McManus, Gavin; O'Doherty, Laura; Gargan, Siobhan; Long, Aideen; Dunne, Jean; Cheallaigh, Cliona Ni; Conlon, Niall; Carty, Michael; Fallon, Padraic G.; Mills, Kingston H. G.; Creagh, Emma M.; O'Donnell, James S.; Hertzog, Paul J.; Hansbro, Philip M.; McLoughlin, Rachel M.; Wygrecka, Malgorzata; Preston, Roger J. S.; Zaslona, Zbigniew; O'Neill, Luke A. J.

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CD4+ T cell calibration of antigen-presenting cells optimizes antiviral CD8+ T cell immunity

NATURE IMMUNOLOGY

IF27.6

2023-05-15

OAAI

Gressier, Elise; Schulte-Schrepping, Jonas; Petrov, Lev; Brumhard, Sophia; Stubbemann, Paula; Hiller, Anna; Obermayer, Benedikt; Spitzer, Jasper; Kostevc, Tomislav; Whitney, Paul G.; Bachem, Annabell; Odainic, Alexandru; van de Sandt, Carolien; Nguyen, Thi H. O.; Ashhurst, Thomas; Wilson, Kayla; Oates, Clare V. L.; Gearing, Linden. J.; Meischel, Tina; Hochheiser, Katharina; Greyer, Marie; Clarke, Michele; Kreutzenbeck, Maike; Gabriel, Sarah S.; Kastenmueller, Wolfgang; Kurts, Christian; Londrigan, Sarah L.; Kallies, Axel; Kedzierska, Katherine; Hertzog, Paul J.; Latz, Eicke; Chen, Yu-Chen E.; Radford, Kristen J.; Chopin, Michael; Schroeder, Jan; Kurth, Florian; Gebhardt, Thomas; Sander, Leif E.; Sawitzki, Birgit; Schultze, Joachim L.; Schmidt, Susanne V.; Bedoui, Sammy

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Targeting of the ETS factor Gabpα disrupts neuromuscular junction synaptic function

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

O'Leary, Debra A.; Noakes, Peter G.; Lavidis, Nick A.; Kola, Ismail; Hertzog, Paul J.; Ristevski, Sika

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Generation and characterization of neuregulin-2-deficient mice

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Britto, JM; Lukehurst, S; Weller, R; Fraser, C; Qiu, YB; Hertzog, P; Busfield, SJ

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The ETS transcription factor GABPα is essential for early embryogenesis

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

133

OAAI

Ristevski, S; O'Leary, DA; Thornell, AP; Owen, MJ; Kola, I; Hertzog, PJ

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Constitutive expression and distinct properties of IFN-epsilon protect the female reproductive tract from Zika virus infection

PLOS PATHOGENS

IF4.9

2023-03-10

OAAI

Coldbeck-Shackley, Rosa C.; Romeo, Ornella; Rosli, Sarah; Gearing, Linden J.; Gould, Jodee A.; Lim, San S.; Van der Hoek, Kylie H.; Eyre, Nicholas S.; Shue, Byron; Robertson, Sarah A.; Best, Sonja M.; Tate, Michelle D.; Hertzog, Paul J.; Beard, Michael R.

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Type 1 interferon suppresses expression and glucocorticoid induction of glucocorticoid-induced leucine zipper (GILZ)

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-11-23

OAAI

Dankers, Wendy; Northcott, Melissa; Bennett, Taylah; D'Cruz, Akshay; Sherlock, Rochelle; Gearing, Linden J. J.; Hertzog, Paul; Russ, Brendan; Miceli, Iolanda; Scheer, Sebastian; Fujishiro, Maki; Hayakawa, Kunihiro; Ikeda, Keigo; Morand, Eric F. F.; Jones, Sarah A. A.

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Research Directions