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B

Bree B. Aldridge

tufts university school of medicine

30H-index
95Paper Count
5.1KCitation Count
Published Papers 45
Publication Date
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PET/CT imaging of tuberculosis lung lesions in marmosets treated with different drug regimens aligns with human clinical outcomes
errScience Translational Medicine
IF14.6
err2026-01-07
err0
PREAI
errTalia Greenstein; Laura E. Via; Mariana Pereira Moraes; Danielle M. Weiner; Emmanuel K. Dayao; April M. Walker; Ayan Abdi; Joel D. Fleegle; Felipe Gomez; Katelyn M. Repoli; Michael J. Woodcock; Helena I. M. Boshoff; Oluwaseun Egbelowo; Kamunkhwala Gausi; Paolo Denti; Firat Kaya; Matthew Zimmerman; Eric L. Miller; Véronique A. Dartois; Clifton E. Barry; Bree B. Aldridge
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errSave
GEODE: an in silico tool that translates in vitro to in vivo predictions of tuberculosis antibiotic combination efficacy
errFrontiers in Pharmacology
IF4.8
err2025-10-17
err0
errOAAI
errMaral Budak; Mariana Pereira Moraes; Talia Greenstein; Pauline Maiello; H. Jacob Borish; Harris B. Chishti; Kara Kracinovsky; Mark Rodgers; Jaime Tomko; Philana Ling Lin; JoAnne L. Flynn; Bree B. Aldridge; Denise Kirschner
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errSave
Integration of multi-modal measurements identifies critical mechanisms of tuberculosis drug action
errCell Systems
IF7.7
err2025-07-29
err0
errOAAI
errWilliam C. Johnson; Ares Alivisatos; Trever C. Smith; Nhi Van; Vijay Soni; Joshua B. Wallach; Nicholas A. Clark; Timothy A. Fitzgerald; Joshua J. Whiteley; Shumin Tan; Artem Sokolov; D. Michael Ando; Dirk Schnappinger; Kyu Y. Rhee; Bree B. Aldridge
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errSave
Unique growth and morphology properties of Clade 5 Clostridioides difficile strains revealed by single-cell time-lapse microscopy
errPLOS PATHOGENS
IF4.9
err2025-05-21
err0
errOAAI
errRibis, John W.; Nieto, Cesar; Dibenedetto, Nicholas V.; Mehra, Anchal; Kuhn, Pola; Dong, Qiwen; Nagawa, Irene; El Meouche, Imane; Aldridge, Bree B.; Dunlop, Mary J.; Tamayo, Rita; Singh, Abhyudai; Shen, Aimee
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errSave
Predicting tuberculosis drug efficacy in preclinical and clinical models from in vitro data
errISCIENCE
IF4.1
err2025-03-01
err0
errOAAI
errGoh, Janice J. N.; Patel, Anu; Ngara, Bernard; van Wijk, Rob C.; Strydom, Natasha; Wang, Qianwen; Van, Nhi; Washington, Tracy M.; Nuermberger, Eric L.; Aldridge, Bree B.; Roubert, Christine; Sarathy, Jansy; Dartois, Veronique; Savic, Rada M.
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errSave
Contribution of front-line, standard-of-care drugs to bactericidal responses, resistance emergence, and cure in murine models of easy- or hard-to-treat tuberculosis disease
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2025-03-01
err0
errOAAI
errPeroutka-Bigus, Nathan; Brooks, Elizabeth J.; Ramey, Michelle E.; D'Erasmo, Hope; Ernest, Jackie P.; Bauman, Allison A.; Woolhiser, Lisa K.; Savic, Radojka M.; Lenaerts, Anne J.; Aldridge, Bree B.; Sarathy, Jansy P.; Robertson, Gregory T.
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errSave
In vitro identification of underutilized β-lactam combinations against methicillin-resistant Staphylococcus aureus bacteremia isolates
errMICROBIOLOGY SPECTRUM
IF3.8
err2024-08-06
err0
errOAAI
errDavis, Kathleen P.; McDermott, Laura A.; Snydman, David R.; Aldridge, Bree B.
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errSave
Critical role of growth medium for detecting drug interactions in Gram-negative bacteria that model in vivo responses
errMBIO
IF4.7
err2024-03-13
err3
errOAAI
errDavis, Kathleen P.; Morales, Yoelkys; Ende, Rachel J.; Peters, Ryan; Mccabe, Anne L.; Mecsas, Joan; Aldridge, Bree B.
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errSave
Novel Synergies and Isolate Specificities in the Drug Interaction Landscape of Mycobacterium abscessus
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2023-07-18
err7
errOAAI
errVan, Nhi; Degefu, Yonatan N.; Leus, Pathricia A.; Larkins-Ford, Jonah; Klickstein, Jacob; Maurer, Florian P.; Stone, David; Poonawala, Husain; Thorpe, Cheleste M.; Smith, Trever C.; Aldridge, Bree B.
errShare
errSave
Confusion
errEMBO REPORTS
IF6.2
err2023-03-06
err0
PREAI
errDarwin, K. Heran; Aldridge, Bree; Seeliger, Jessica; Shen, Aimee; Stanley, Sarah
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errSave
Advances in the design of combination therapies for the treatment of tuberculosis
errEXPERT OPINION ON DRUG DISCOVERY
IF4.9
err2022-12-28
err15
errOAAI
errLarkins-Ford, Jonah; Aldridge, Bree B.
errShare
errSave
Design principles to assemble drug combinations for effective tuberculosis therapy using interpretable pairwise drug response measurements
errCELL REPORTS MEDICINE
IF10.6
err2022-09-01
err23
errOAAI
errLarkins-Ford, Jonah; Degefu, Yonatan N.; Van, Nhi; Sokolov, Artem; Aldridge, Bree B.
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errSave
C25-modified rifamycin derivatives with improved activity against Mycobacterium abscessus
errPNAS NEXUS
IF3.8
err2022-08-09
err5
errOAAI
errPaulowski, Laura; Beckham, Katherine S. H.; Johansen, Matt D.; Berneking, Laura; Nhi Van; Degefu, Yonatan; Staack, Sonja; Sotomayor, Flor Vasquez; Asar, Lucia; Rohde, Holger; Aldridge, Bree B.; Aepfelbacher, Martin; Parret, Annabel; Wilmanns, Matthias; Kremer, Laurent; Combrink, Keith; Maurer, Florian P.
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errSave
Localization of EccA3 at the growing pole in Mycobacterium smegmatis
errBMC MICROBIOLOGY
IF4.2
err2022-05-19
err2
errOAAI
errKriel, Nastassja L.; Newton-Foot, Mae; Bennion, Owen T.; Aldridge, Bree B.; Mehaffy, Carolina; Belisle, John T.; Walzl, Gerhard; Warren, Robin M.; Sampson, Samantha L.; van Pittius, Nico C. Gey
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errSave
Identification of cell wall synthesis inhibitors active against Mycobacterium tuberculosis by competitive activity-based protein profiling
errCELL CHEMICAL BIOLOGY
IF7.2
err2022-05-01
err22
errOAAI
errLi, Michael; Patel, Hiren, V; Cognetta, Armand B., III; Smith, Trever C., II; Mallick, Ivy; Cavalier, Jean-Francois; Previti, Mary L.; Canaan, Stephane; Aldridge, Bree B.; Cravatt, Benjamin F.; Seeliger, Jessica C.
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errSave
Types and functions of heterogeneity in mycobacteria
errNATURE REVIEWS MICROBIOLOGY
IF103.3
err2022-04-01
err25
errOAAI
errChung, Eun Seon; Johnson, William C.; Aldridge, Bree B.
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errSave
Leveraging laboratory and clinical studies to design effective antibiotic combination therapy
errCURRENT OPINION IN MICROBIOLOGY
IF7.5
err2021-12-01
err6
errOAAI
errDavis, Kathleen; Greenstein, Talia; Colindres, Roberto Viau; Aldridge, Bree B.
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errSave
Systematic measurement of combination-drug landscapes to predict in vivo treatment outcomes for tuberculosis
errCELL SYSTEMS
IF7.7
err2021-11-01
err34
errOAAI
errLarkins-Ford, Jonah; Greenstein, Talia; Van, Nhi; Degefu, Yonatan N.; Olson, Michaela C.; Sokolov, Artem; Aldridge, Bree B.
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errSave
Pharmacokinetics and Target Attainment of SQ109 in Plasma and Human-Like Tuberculosis Lesions in Rabbits
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2021-08-17
err15
errOAAI
errEgbelowo, Oluwaseun; Sarathy, Jansy P.; Gausi, Kamunkhwala; Zimmerman, Matthew D.; Wang, Han; Wijnant, Gert-Jan; Kaya, Firat; Gengenbacher, Martin; Van, Nhi; Degefu, Yonatan; Nacy, Carol; Aldridge, Bree B.; Carter, Claire L.; Denti, Paolo; Dartois, Veronique
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errSave
The Tuberculosis Drug Accelerator at year 10: what have we learned?
errNATURE MEDICINE
IF50
err2021-07-05
err39
errOAAI
errAldridge, Bree B.; Barros-Aguirre, David; Barry, Clifton E., III; Bates, Robert H.; Berthel, Steven J.; Boshoff, Helena I.; Chibale, Kelly; Chu, Xin-Jie; Cooper, Christopher B.; Dartois, Veronique; Duncan, Ken; Fotouhi, Nader; Gusovsky, Fabian; Hipskind, Philip A.; Kempf, Dale J.; Lelievre, Joel; Lenaerts, Anne J.; McNamara, Case W.; Mizrahi, Valerie; Nathan, Carl; Olsen, David B.; Parish, Tanya; Petrassi, H. Michael; Pym, Alexander; Rhee, Kyu Y.; Robertson, Gregory T.; Rock, Jeremy Michael; Rubin, Eric J.; Russell, Betsy; Russell, David G.; Sacchettini, James C.; Schnappinger, Dirk; Schrimpf, Michael; Upton, Anna M.; Warner, Peter; Wyatt, Paul Graham; Yuan, Ying
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Research Directions

No research directions
Co-authors
Cooperation Journals
D
David L. Kaplan
H-index: 194 · Papers: 2.4K
N
Nicholas J. White
H-index: 186 · Papers: 2.0K
J
James J. Collins
H-index: 162 · Papers: 589
B
Benjamin F. Cravatt
H-index: 148 · Papers: 867
C
Carl Nathan
H-index: 127 · Papers: 424
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