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Nanopore DNA Methylation Sequencing Simulates Rapid Intraoperative Diagnosis of Pediatric Brain Tumors Jarvis, Casey; Benfatto, Salvatore; Castellani, Sophia; Couvillon, Elsa; Abdullaev, Ziedulla; Lidov, Hart; Adalpe, Kenneth; Hovestadt, Volker; Alexandrescu, Sanda; Filbin, Mariella; Baird, Lissa Share Save
MACHINE LEARNING AND MULTI-OMIC ANALYSIS IDENTIFY A MICROENVIRONMENT-DRIVEN MENINGIOMA RISK CONTINUUM UNDERLYING MOLECULAR CLASSIFICATIONS Maas, Sybren; Tang, Yiheng; Stutheit-Zhao, Eric; Rahmanzade, Ramin; Hielscher, Thomas; Zettl, Ferdinand; Benfatto, Salvatore; Calafato, Domenico; Sill, Martin; Benotmane, Jasim Kada; Yabo, Yahaya; Peyre, Matthieu; Sankowski, Roman; Okonechnikov, Konstantin; Sievers, Philip; Patel, Areeba; Reuss, David; Hanemann, Oliver; Lamszus, Katrin; Etminan, Nima; Unterberg, Andreas; Mawrin, Christian; Grossmann, Rachel; Ram, Zvi; Ratliff, Miriam; Neidert, Marian; Bos, Eelke; Prinz, Marco; Weller, Michael; Acker, Till; Hartmann, Felix; Preusser, Matthias; Tabatabai, Ghazaleh; Herold-Mende, Christel; Krieg, Sandro; Jones, David; Pfister, Stefan; Wick, Wolfgang; Kalamarides, Michel; Von Deimling, Andreas; Heiland, Dieter Henrik; Hovestadt, Volker; Gerstung, Moritz; Schlesner, Matthias; Sahm, Felix Share Save
Cellular hierarchies of embryonal tumors with multilayered rosettes are shaped by oncogenic microRNAs and receptor-ligand interactions Gabler-Pamer, Lisa; Beck, Alexander; Cruzeiro, Gustavo Alencastro Veiga; Lambo, Sander; Shaw, Mckenzie L.; Hack, Olivia A.; Nascimento, Andrezza; Madlener, Sibylle; Lotsch, Daniela; Slavc, Irene; Dorfer, Christian; Haberler, Christine; Baird, Lissa; Chi, Susan N.; Alexandrescu, Sanda; Gojo, Johannes; Marcel, Kool; Hovestadt, Volker; Filbin, Mariella G. Share Save
Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold standard Lin, Yu-Yu; Breuer, Kersten; Weichenhan, Dieter; Lafrenz, Pascal; Sarnataro, Antonella; Wilk, Agata; Chepeleva, Maryna; Mucke, Oliver; Schonung, Maximilian; Petermann, Franziska; Kensche, Philip Reiner; Weiser, Lena; Thommen, Frank; Giacomelli, Gideon; Nordstroem, Karl; Gonzalez-Avalos, Edahi; Merkel, Angelika; Kretzmer, Helene; Fischer, Jonas; Kramer, Stephen; Iskar, Murat; Wolf, Stephan; Buchhalter, Ivo; Esteller, Manel; Lawerenz, Christian; Twardziok, Sven; Zapatka, Marc; Hovestadt, Volker; Schlesner, Matthias; Schulz, Marcel H.; Hoffmann, Steve; Gerhauser, Clarissa; Walter, Jorn; Hartmann, Mark; Lipka, Daniel B.; Assenov, Yassen; Bock, Christoph; Plass, Christoph; Toth, Reka; Lutsik, Pavlo Share Save
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Cellular hierarchies of embryonal tumors with multilayered rosettes are shaped by oncogenic microRNAs and receptor-ligand interactions Beck, Alexander; Gabler-Pamer, Lisa; Alencastro Veiga Cruzeiro, Gustavo; Lambo, Sander; Englinger, Bernhard; Shaw, McKenzie L.; Hack, Olivia A.; Liu, Ilon; Haase, Rebecca D.; de Biagi Jr, Carlos A. O.; Baumgartner, Alicia; Nascimento Silva, Andrezza Do; Klenner, Marbod; Freidel, Pia S.; Herms, Jochen; von Baumgarten, Louisa; Tonn, Joerg C.; Thon, Niklas; Bruckner, Katharina; Madlener, Sibylle; Mayr, Lisa; Senfter, Daniel; Peyrl, Andreas; Slavc, Irene; Loetsch, Daniela; Dorfer, Christian; Geyregger, Rene; Amberg, Nicole; Haberler, Christine; Mack, Norman; Schwalm, Benjamin; Pfister, Stefan M.; Korshunov, Andrey; Baird, Lissa C.; Yang, Edward; Chi, Susan N.; Alexandrescu, Sanda; Gojo, Johannes; Kool, Marcel; Hovestadt, Volker; Filbin, Mariella G. Share Save
GENE REGULATORY NETWORK LANDSCAPE OF GROUP 3/4 MEDULLOBLASTOMA Joshi, Piyush; Stelzer, Tamina; Okonechnikov, Konstantin; Sarropoulos, Ioannis; Sepp, Mari; Pour-Jamnani, Mischan, V; Rademacher, Anne; Yamada-Saito, Tetsuya; Schneider, Celine; Schmidt, Julia; Schaefer, Philipp; Leiss, Kevin; Bortolomeazzi, Michele; Mallm, Jan-Philipp; da Silva, Patricia B. G.; Statz, Britta; Wittmann, Andrea; Schramm, Kathrin; Blattner-Johnson, Mirjam; Fiesel, Petra; Jones, Barbara; Milde, Till; Pajtler, Kristian; van Tilburg, Cornelis M.; Witt, Olaf; Rippe, Karsten; Korshunov, Andrey; Jones, David T. W.; Hovestadt, Volker; Northcott, Paul A.; Thongjuea, Supat; Jaeger, Natalie; Kaessmann, Henrik; Pfister, Stefan M.; Kutscher, Lena M. Share Save
MULTI-OMICS SEQUENCING OF ATYPICAL TERATOID RHABDOID TUMORS UNVEILS A SHARED GROUND-STATE POPULATION PROMOTING SUBGROUP-SPECIFIC DIFFERENTIATION TRAJECTORIES Carmona, Enrique Blanco; Paassen, Irene; He, Jiayou; Buellesbach, Annette; Buhl, Juliane L.; Federico, Aniello; Liu, Ilon; Young, Matthew; Kildisiute, Gerda; Behjati, Sam; Vibhakar, Rajeev; Donson, Andrew; Foreman, Nicholas; Hovestadt, Volker; Shaw, McKenzie; Chi, Susan N.; Fruehwald, Michael; Korshunov, Andrey; Hasselblatt, Martin; Hoving, Eelco W.; Jaeger, Natalie; Johann, Pascal D.; Pfister, Stefan M.; Filbin, Mariella; Drost, Jarno; Kool, Marcel Share Save
BCOR/L1-ALTERATIONS REWIRE HISTONE REGULATION TO INDUCE ONCOGENIC PATHWAYS IN PEDIATRIC CENTRAL NERVOUS SYSTEM TUMORS Bruckner, Katharina; Loetsch-Gojo, Daniela; Gabler, Lisa; Wang, Shanzheng; Kirchhofer, Dominik; Labelle, Jenna; Madlener, Sibylle; Senfter, Daniel; Schmitt-Hoffner, Felix; Federico, Aniello; Koster, Jan; Dorfer, Christian; Tauziede-Espariat, Arnault; Pahnke, Jens; Hovestadt, Volker; Beck, Alexander; Schueler, Julia; Haberler, Christine; Berger, Walter; Filbin, Mariella G.; Kool, Marcel; Gojo, Johannes Share Save
A prognostic neural epigenetic signature in high-grade glioma Drexler, Richard; Khatri, Robin; Sauvigny, Thomas; Mohme, Malte; Maire, Cecile L.; Ryba, Alice; Zghaibeh, Yahya; Duehrsen, Lasse; Salviano-Silva, Amanda; Lamszus, Katrin; Westphal, Manfred; Gempt, Jens; Wefers, Annika K.; Neumann, Julia E.; Bode, Helena; Hausmann, Fabian; Huber, Tobias B.; Bonn, Stefan; Juetten, Kerstin; Delev, Daniel; Weber, Katharina J.; Harter, Patrick N.; Onken, Julia; Vajkoczy, Peter; Capper, David; Wiestler, Benedikt; Weller, Michael; Snijder, Berend; Buck, Alicia; Weiss, Tobias; Goeller, Pauline C.; Sahm, Felix; Menstel, Joelle Aline; Zimmer, David Niklas; Keough, Michael B.; Ni, Lijun; Monje, Michelle; Silverbush, Dana; Hovestadt, Volker; Suva, Mario L.; Krishna, Saritha; Hervey-Jumper, Shawn L.; Schueller, Ulrich; Heiland, Dieter H.; Haenzelmann, Sonja; Ricklefs, Franz L. Share Save
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Temporal change of DNA methylation subclasses between matched newly diagnosed and recurrent glioblastoma Drexler, Richard; Khatri, Robin; Schueller, Ulrich; Eckhardt, Alicia; Ryba, Alice; Sauvigny, Thomas; Duehrsen, Lasse; Mohme, Malte; Ricklefs, Tammo; Bode, Helena; Hausmann, Fabian; Huber, Tobias B.; Bonn, Stefan; Voss, Hannah; Neumann, Julia E.; Silverbush, Dana; Hovestadt, Volker; Suva, Mario L.; Lamszus, Katrin; Gempt, Jens; Westphal, Manfred; Heiland, Dieter H.; Haenzelmann, Sonja; Ricklefs, Franz L. Share Save
Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology (vol 29, pg 917, 2023) Sturm, Dominik; Capper, David; Andreiuolo, Felipe; Gessi, Marco; Koelsche, Christian; Reinhardt, Annekathrin; Sievers, Philipp; Wefers, Annika K.; Ebrahimi, Azadeh; Suwala, Abigail K.; Gielen, Gerrit H.; Sill, Martin; Schrimpf, Daniel; Stichel, Damian; Hovestadt, Volker; Daenekas, Bjarne; Rode, Agata; Hamelmann, Stefan; Previti, Christopher; Jaeger, Natalie; Buchhalter, Ivo; Blattner-Johnson, Mirjam; Jones, Barbara C.; Warmuth-Metz, Monika; Bison, Brigitte; Grund, Kerstin; Sutter, Christian; Hirsch, Steffen; Dikow, Nicola; Hasselblatt, Martin; Schueller, Ulrich; Koch, Arend; Gerber, Nicolas U.; White, Christine L.; Buntine, Molly K.; Kinross, Kathryn; Algar, Elizabeth M.; Hansford, Jordan R.; Gottardo, Nicholas G.; Schuhmann, Martin U.; Thomale, Ulrich W.; Driever, Pablo; Gnekow, Astrid; Witt, Olaf; Mueller, Hermann L.; Calaminus, Gabriele; Fleischhack, Gudrun; Kordes, Uwe; Mynarek, Martin; Rutkowski, Stefan; Fruehwald, Michael C.; Kramm, Christof M.; von Deimling, Andreas; Pietsch, Torsten; Sahm, Felix; Pfister, Stefan M.; Jones, David. T. W. Share Save
Mapping pediatric brain tumors to their origins in the developing cerebellum Okonechnikov, Konstantin; Joshi, Piyush; Sepp, Mari; Leiss, Kevin; Sarropoulos, Ioannis; Murat, Florent; Sill, Martin; Beck, Pengbo; Chan, Kenneth Chun-Ho; Korshunov, Andrey; Sah, Felix; Deng, Maximilian Y.; Sturm, Dominik; DeSisto, John; Donson, Andrew M.; Foreman, Nicholas K.; Green, Adam L.; Robinson, Giles; Orr, Brent A.; Gao, Qingsong; Darrow, Emily; Hadley, Jennifer L.; Northcott, Paul A.; Gojo, Johannes; Kawauchi, Daisuke; Hovestadt, Volker; Filbin, Mariella G.; von Deimling, Andreas; Zuckermann, Marc; Pajtler, Kristian W.; Kool, Marcel; Jones, David T. W.; Jaeger, Natalie; Kutscher, Lena M.; Kaessmann, Henrik; Pfister, Stefan M. Share Save
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