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J

James D. Griffin

Dana-Farber Cancer Institute

110H-index
628Paper Count
4.6WCitation Count
Published Papers 121
Publication Date
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Allosteric inhibition of JAK2 with lysine-reactive compounds that bind the pseudokinase domain
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-10-21
err0
PREAI
errMarina C. Primi; Maurício T. Tavares; John M. Hatcher; Hyelim Kang; Tomás A.C. Kresina; Sayan Chakraborty; Emilie Leroy; Anna M. Schmoker; Hyesung Jeon; Ellen L. Weisberg; Taisei Akatsu; James D. Griffin; David A. Scott; Michael J. Eck
errShare
errSave
Apoptosis-targeting BH3 mimetics: transforming treatment for patients with acute myeloid leukaemia
errNature Reviews Clinical Oncology
IF82.2
err2025-09-01
err0
PREAI
errAntonino Glaviano; Ellen Weisberg; Hiu Y. Lam; Donavan J. J. Tan; Andrew J. Innes; Yubin Ge; Catherine E. Lai; Wendy Stock; Christina Glytsou; Linda Smit; Tatsushi Yoshida; Tian Y. Zhang; Vanessa E. Kennedy; B. Douglas Smith; Thomas Mercher; Stéphane de Botton; Patrizia Diana; Marina Konopleva; Michael J. Mauro; James D. Griffin; Courtney D. DiNardo; Alan P. Kumar
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errSave
Pornography, sexual privacy and copyright
errCOMPUTER LAW & SECURITY REVIEW
IF3.2
err2024-09-01
err0
errOAAI
errNair, Abhilash; Griffin, James
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errSave
BRD9 regulates normal human hematopoietic stem cell function and lineage differentiation
errCELL DEATH AND DIFFERENTIATION
IF15.4
err2024-05-30
err0
errOAAI
errGarg, Swati; Ni, Wei; Chowdhury, Basudev; Weisberg, Ellen L.; Sattler, Martin; Griffin, James D.
errShare
errSave
Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth
errCELL REPORTS
IF6.9
err2023-12-01
err3
errOAAI
errColeman, Daniel J. L.; Keane, Peter; Luque-Martin, Rosario; Chin, Paulynn S.; Blair, Helen; Ames, Luke; Kellaway, Sophie G.; Griffin, James; Holmes, Elizabeth; Potluri, Sandeep; Assi, Salam A.; Bushweller, John; Heidenreich, Olaf; Cockerill, Peter N.; Bonifer, Constanze
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errSave
Hypomethylating agent decitabine sensitizes diffuse large B-cell lymphoma to venetoclax
errHAEMATOLOGICA
IF7.9
err2023-08-03
err7
errOAAI
errZhu, Fen; Crombie, Jennifer L.; Ni, Wei; Hoang, Nguyet-Minh; Garg, Swati; Hackett, Liam; Chong, Stephen J. F.; Collins, Mary C.; Rui, Lixin; Griffin, James; Davids, Matthew S.
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errSave
Inhibiting β-catenin in AML by targeting DDX5
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errNi, Wei; Garg, Swati; Zhu, Fen; Weisberg, Ellen L.; Chowdhury, Basudev; Sattler, Martin; Jakkani, Amulya; Liu, Suiyang; Sanchez, Dana M.; Wu, Lizi; Stone, Richard M.; Davids, Matthew S.; Griffin, James D.
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errSave
Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err415
errOAAI
errWeng, AP; Nam, Y; Wolfe, MS; Pear, WNS; Griffin, JD; Blacklow, SC; Aster, JC
errShare
errSave
Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err273
errOAAI
errWu, L; Sun, T; Kobayashi, K; Gao, P; Griffin, JD
errShare
errSave
Anti-SARS-CoV-2 activity of targeted kinase inhibitors: Repurposing clinically available drugs for COVID-19 therapy
errJOURNAL OF MEDICAL VIROLOGY
IF4.6
err2022-09-28
err18
errOAAI
errBoytz, RuthMabel; Slabicki, Mikolaj; Ramaswamy, Sita; Patten, J. J.; Zou, Charles; Meng, Chengcheng; Hurst, Brett L.; Wang, Jinhua; Nowak, Radoslaw P.; Yang, Priscilla L.; Sattler, Martin; Stone, Richard M.; Griffin, James D.; Gray, Nathanael S.; Gummuluru, Suryaram; Davey, Robert A.; Weisberg, Ellen
errShare
errSave
BRD9 degraders as chemosensitizers in acute leukemia and multiple myeloma
errBLOOD CANCER JOURNAL
IF11.6
err2022-07-19
err26
errOAAI
errWeisberg, Ellen; Chowdhury, Basudev; Meng, Chengcheng; Case, Abigail E.; Ni, Wei; Garg, Swati; Sattler, Martin; Azab, Abdel Kareem; Sun, Jennifer; Muz, Barbara; Sanchez, Dana; Toure, Anthia; Stone, Richard M.; Galinsky, Ilene; Winer, Eric; Gleim, Scott; Gkountela, Sofia; Kedves, Alexia; Harrington, Edmund; Abrams, Tinya; Zoller, Thomas; Vaupel, Andrea; Manley, Paul; Faller, Michael; Chung, BoYee; Chen, Xin; Busenhart, Philipp; Stephan, Christine; Calkins, Keith; Bonenfant, Debora; Thoma, Claudio R.; Forrester, William; Griffin, James D.
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errSave
Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2
errLEUKEMIA
IF13.4
err2022-01-17
err10
PREAI
errYang, Jing; Weisberg, Ellen L.; Qi, Shuang; Ni, Wei; Mei, Husheng; Wang, Zuowei; Meng, Chengcheng; Zhang, Shengzhe; Hou, Mingqi; Qi, Ziping; Wang, Aoli; Jiang, Yunyun; Jiang, Zongru; Huang, Tao; Liu, Qingwang; Magin, Robert S.; Doherty, Laura; Wang, Wenchao; Liu, Jing; Buhrlage, Sara J.; Liu, Qingsong; Griffin, James D.
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errSave
Small molecule inhibition of deubiquitinating enzyme JOSD1 as a novel targeted therapy for leukemias with mutant JAK2
errLEUKEMIA
IF13.4
err2021-07-29
err18
PREAI
errYang, Jing; Weisberg, Ellen L.; Liu, Xiaoxi; Magin, Robert S.; Chan, Wai Cheung; Hu, Bin; Schauer, Nathan J.; Zhang, Shengzhe; Lamberto, Ilaria; Doherty, Laura; Meng, Chengcheng; Sattler, Martin; Cabal-Hierro, Lucia; Winer, Eric; Stone, Richard; Marto, Jarrod A.; Griffin, James D.; Buhrlage, Sara J.
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errSave
Essential role of the histone lysine demethylase KDM4A in the biology of malignant pleural mesothelioma (MPM)
errBRITISH JOURNAL OF CANCER
IF6.8
err2021-06-04
err10
errOAAI
errLapidot, Moshe; Case, Abigail E.; Weisberg, Ellen L.; Meng, Chengcheng; Walker, Sarah R.; Garg, Swati; Ni, Wei; Podar, Klaus; Hung, Yin P.; Carrasco, Ruben D.; Knott, Aine; Gokhale, Prafulla C.; Sharma, Sunil; Pozhitkov, Alex; Kulkarni, Prakash; Frank, David A.; Salgia, Ravi; Griffin, James D.; Saladi, Srinivas V.; Bueno, Raphael; Sattler, Martin
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errSave
The CRTC1-MAML2 fusion is the major oncogenic driver in mucoepidermoid carcinoma
errJCI INSIGHT
IF6.1
err2021-04-08
err50
errOAAI
errChen, Zirong; Ni, Wei; Li, Jian-Liang; Lin, Shuibin; Zhou, Xin; Sun, Yuping; Li, Jennifer W.; Leon, Marino E.; Hurtado, Maria D.; Zolotukhin, Sergei; Liu, Chen; Lu, Jianrong; Griffin, James D.; Kaye, Frederic J.; Wu, Lizi
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errSave
Repurposing of Kinase Inhibitors for Treatment of COVID-19
errPHARMACEUTICAL RESEARCH
IF4.3
err2020-08-10
err101
errOAAI
errWeisberg, Ellen; Parent, Alexander; Yang, Priscilla L.; Sattler, Martin; Liu, Qingsong; Liu, Qingwang; Wang, Jinhua; Meng, Chengcheng; Buhrlage, Sara J.; Gray, Nathanael; Griffin, James D.
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errSave
Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism
errSCIENTIFIC REPORTS
IF3.9
err2020-03-24
err83
errOAAI
errSchauer, Nathan J.; Liu, Xiaoxi; Magin, Robert S.; Doherty, Laura M.; Chan, Wai Cheung; Ficarro, Scott B.; Hu, Wanyi; Roberts, Rebekka M.; Iacob, Roxana E.; Stolte, Bjoern; Giacomelli, Andrew O.; Perera, Sumner; McKay, Kyle; Boswell, Sarah A.; Weisberg, Ellen L.; Ray, Arghya; Chauhan, Dharminder; Dhe-Paganon, Sirano; Anderson, Ken C.; Griffin, James D.; Li, Jianing; Hahn, William C.; Sorger, Peter K.; Engen, John R.; Stegmaier, Kimberly; Marto, Jarrod A.; Buhrlage, Sara J.
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errSave
Evaluation of ERK as a therapeutic target in acute myelogenous leukemia (vol 13, pg 234, 2020)
errLEUKEMIA
IF13.4
err2020-03-06
err3
errOAAI
errWeisberg, Ellen; Meng, Chengcheng; Case, Abigail; Sattler, Martin; Tiv, Hong L.; Gokhale, Prafulla C.; Buhrlage, Sara; Wang, Jinhua; Gray, Nathanael; Stone, Richard; Liu, Suiyang; Bhagwat, Shripad V.; Tiu, Ramon V.; Adamia, Sophia; Griffin, James D.
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errSave
Inhibition of the deubiquitinase USP10 induces degradation of SYK
errBRITISH JOURNAL OF CANCER
IF6.8
err2020-02-04
err22
errOAAI
errYang, Jing; Meng, Chengcheng; Weisberg, Ellen; Case, Abigail; Lamberto, Ilaria; Magin, Robert S.; Adamia, Sophia; Wang, Jinhua; Gray, Nathanael; Liu, Suiyang; Stone, Richard; Sattler, Martin; Buhrlage, Sara; Griffin, James D.
errShare
errSave
Evaluation of ERK as a therapeutic target in acute myelogenous leukemia
errLEUKEMIA
IF13.4
err2019-08-27
err12
errOAAI
errWeisberg, Ellen; Meng, Chengcheng; Case, Abigail; Sattler, Martin; Tiv, Hong L.; Gokhale, Prafulla C.; Buhrlage, Sara; Wang, Jinhua; Gray, Nathanael; Stone, Richard; Liu, Suiyang; Bhagwat, Shripad V.; Tiu, Ramon V.; Adamia, Sophia; Griffin, James D.
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Kenneth C. Anderson
H-index: 199 · Papers: 3.1K
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Jörge E. Cortes
H-index: 179 · Papers: 3.6K
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Paul G. Richardson
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