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INVESTIGATION OF THE COMBINATION OF D2C7-IT WITH AN FC-ENGINEERED ANTI-HUMANCD40 MONOCLONAL ANTIBODY (2141-V11) WHEN ADMINISTERED INTRATUMORALLY VIA CONVECTION-ENHANCED DELIVERY (CED) FOLLOWED BY CERVICAL PERILYMPHATIC INJECTIONS (CPLIS) OF 2141-V11 COMPARED TO D2C7-IT CED MONOTHERAPY IN PATIENTS WITH RECURRENT GLIOBLASTOMA (RGBM) Desjardins, Annick; Chandramohan, Vidya; Herndon II, James E.; Bradbury, Claire; Shoaf, Madison; Peters, Katherine B.; Johnson, Margaret O.; Batich, Kristen; Low, Justin; Khasraw, Mustafa; Friedman, Allan H.; Friedman, Henry S.; Ashley, David M.; Grant, Gerald; Osorio, Juan; Ravetch, Jeffrey; Bigner, Darell D. Share Save
An assessment of the Tumor Monorail Device (TMD) for repeated sampling as part of a trial evaluating the combination of D2C7-IT and an Fc-engineered anti-CD40 monoclonal antibody (2141-V11) administered intratumorally via convection-enhanced delivery (CED) and cervical perilymphatic injections (CPLIs) of 2141-V11 in recurrent glioblastoma (rGBM) patients Desjardins, Annick; Chandramohan, Vidya; Mokarram, Nassir; Meehan, Sean; Sharma, Shaili; Herndon Ii, James E.; Shoaf, Madison; Peters, Katherine B.; Johnson, Margaret O.; Batich, Kristen; Low, Justin; Khasraw, Mustafa; Friedman, Allan H.; Friedman, Henry S.; Ashley, David M.; Grant, Gerald; Osorio, Juan; Ravetch, Jeffrey; Bellamkonda, Ravi; Bigner, Darell D. Share Save
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D2C7-IT IN COMBINATION WITH AN FC-ENGINEERED ANTI-HUMANCD40 MONOCLONAL ANTIBODY (2141-V11) ADMINISTERED INTRATUMORALLY VIA CONVECTION-ENHANCED DELIVERY (CED) FOLLOWED BY CERVICAL PERILYMPHATIC INJECTIONS (CPLIS) OF 2141-V11 IN PATIENTS WITH RECURRENT GLIOBLASTOMA (RGBM) Desjardins, Annick; Chandramohan, Vidya; Herndon, James E., II; Threatt, Stevie; Bullock, Chevelle; Bradbury, Claire; Johnson, Margaret O.; Khasraw, Mustafa; Low, Justin T.; Peters, Katherine B.; Shoaf, Madison; Landi, Daniel; Batich, Kristen; Friedman, Allan H.; Friedman, Henry S.; Ashley, David M.; Knorr, David; Osorio, Juan; Ravetch, Jeffrey; Bigner, Darell D. Share Save
PHASE I STUDY OF INTRAVESICAL FC-OPTIMIZED ANTI-CD40 AGONIST ANTIBODY 2141-V11 FOR NON-MUSCLE INVASIVE BLADDER CANCER (NMIBC) UNRESPONSIVE TO BACILLUS CALMETTE-GUERIN (BCG) Bochner, Bernard H.; Alam, Muneeb; Osorio, Juan C.; Wong, Jeffrey L.; Knorr, David; Blanchard, Lucas; Angulo-Lozano, Juan; Whiting, Karissa; Seshan, Venkatraman E.; Donahue, Timothy; Cha, Eugene; Goh, Alvin; Smith, Robert; Dalbagni, Guido; Hernandez, Christian; McCarter, Melissa; Pietzak, Eugene J.; Rosenberg, Jonathan E.; Ravetch, Jeffrey V. Share Save
Phase I study of intravesical Fc-optimized anti-CD40 agonist antibody 2141-V11 for non-muscle invasive bladder cancer (NMIBC) unresponsive to Bacillus Calmette-Guerin (BCG) therapy Osorio, Juan C.; Alam, Muneeb; Wong, Jeffrey; Knorr, David; Blanchard, Lucas; Angulo-Lozano, Juan C.; Whiting, Karissa; Seshan, Venkatraman E.; Donahue, Timothy F.; Cha, Eugene K.; Goh, Alvin C.; Smith, Robert; Dalbagni, Guido; Hernandez, Christian; McCarter, Melissa; Pietzak, Eugene J.; Rosenberg, Jonathan E.; Ravetch, Jeffrey V.; Bochner, Bernard H. Share Save
Tissue niche occupancy determines the contribution of fetal- versus bone-marrow-derived macrophages to IgG effector functions Woehner, Miriam; Brechtelsbauer, Sarah; Friedrich, Niklas; Vorsatz, Christof; Bulang, Johanna; Liang, Chunguang; Schorr, Lena; Beschin, Alain; Guilliams, Martin; Ravetch, Jeffrey; Nimmerjahn, Falk; Biburger, Markus Share Save
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Systematic evaluation of AML-associated antigens identifies anti-U5 SNRNP200 therapeutic antibodies for the treatment of acute myeloid leukemia Knorr, Katherine; Rahman, Jahan; Erickson, Caroline; Wang, Eric; Monetti, Mara; Li, Zhuoning; Ortiz-Pacheco, Juliana; Jones, Andrew; Lu, Sydney X.; Stanley, Robert F.; Baez, Maria; Fox, Nina; Castro, Cynthia; Marino, Alessandra E.; Jiang, Caroline; Penson, Alex; Hogg, Simon J.; Mi, Xiaoli; Nakajima, Hideaki; Kunimoto, Hiroyoshi; Nishimura, Koutarou; Inoue, Daichi; Greenbaum, Benjamin; Knorr, David; Ravetch, Jeffrey; Abdel-Wahab, Omar Share Save
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IL-15 synergizes with CD40 agonist antibodies to induce durable immunity against bladder cancer Wong, Jeffrey L.; Smith, Patrick; Angulo-Lozano, Juan; Ranti, Daniel; Bochner, Bernard H.; Sfakianos, John P.; Horowitz, Amir; Ravetch, Jeffrey, V; Knor, David A. Share Save
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Synthetic nanobodies as tools to distinguish IgG Fc glycoforms Kao, Kevin S.; Gupta, Aaron; Zong, Guanghui; Li, Chao; Kerschbaumer, Isabell; Borghi, Sara; Achkar, Jacqueline M.; Bournazos, Stylianos; Wang, Lai-Xi; Ravetch, Jeffrey V. Share Save
PD-1 directed immunotherapy alters Tfh and humoral immune responses to seasonal influenza vaccine Herati, Ramin Sedaghat; Knorr, David A.; Vella, Laura A.; Silva, Luisa Victoria; Chilukuri, Lakshmi; Apostolidis, Sokratis A.; Huang, Alexander C.; Muselman, Alexander; Manne, Sasikanth; Kuthuru, Oliva; Staupe, Ryan P.; Adamski, Sharon A.; Kannan, Senthil; Kurupati, Raj K.; Ertl, Hildegund C. J.; Wong, Jeffrey L.; Bournazos, Stylianos; McGettigan, Suzanne; Schuchter, Lynn M.; Kotecha, Ritesh R.; Funt, Samuel A.; Voss, Martin H.; Motzer, Robert J.; Lee, Chung-Han; Bajorin, Dean F.; Mitchell, Tara C.; Ravetch, Jeffrey, V; Wherry, E. John Share Save
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