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SaveShare Save Share Save High-throughput screen of 100 000 small molecules in C9ORF72 ALS neurons identifies spliceosome modulators that mobilize G4C2 repeat RNA into nuclear export and repeat associated non-canonical translation
Luteijn, Maartje J.; Bhaskar, Varun; Trojer, Dominic; Schuerz, Melanie; Mahboubi, Hicham; Handl, Cornelia; Pizzato, Nicolas; Pfeifer, Martin; Dafinca, Ruxandra; Voshol, Hans; Giorgetti, Elisa; Manneville, Carole; Garnier, Isabelle P. M.; Mueller, Matthias; Zeng, Fanning; Buntin, Kathrin; Markwalder, Roger; Schroeder, Harald; Weiler, Jan; Khar, Dora; Schuhmann, Tim; Groot-Kormelink, Paul J.; Keller, Caroline Gubser; Farmer, Pierre; MacKay, Angela; Beibel, Martin; Roma, Guglielmo; D'Ario, Giovanni; Merkl, Claudia; Schebesta, Michael; Hild, Marc; Elwood, Fiona; Vahsen, Bjoern F.; Ripin, Nina; Clery, Antoine; Allain, Frederic; Labow, Mark; Gabriel, Daniela; Chao, Jeffrey A.; Talbot, Kevin; Nash, Mark; Hunziker, Juerg; Meisner-Kober, Nicole C. Share Save Cell-type-specific requirement for TYK2 in murine immune cells under steady state and challenged conditionsKarjalainen, Anzhelika; Witalisz-Siepracka, Agnieszka; Prchal-Murphy, Michaela; Martin, David; Sternberg, Felix; Krunic, Milica; Dolezal, Marlies; Fortelny, Nikolaus; Farlik, Matthias; Macho-Maschler, Sabine; Lassnig, Caroline; Meissl, Katrin; Amenitsch, Lena; Lederer, Therese; Pohl, Elena; Gotthardt, Dagmar; Bock, Christoph; Decker, Thomas; Strobl, Birgit; Mueller, Mathias Share Save Lack of TYK2 signaling enhances host resistance to Candida albicans skin infectionMiranda, Sara; Lassnig, Caroline; Schmidhofer, Kristina; Kjartansdottir, Hroenn; Vogl, Claus; Tangermann, Simone; Tsymala, Irina; Babl, Verena; Mueller, Mathias; Kuchler, Karl; Strobl, Birgit Share Save Augmentative effects of leukemia inhibitory factor reveal a critical role for TYK2 signaling in vascular calcificationAlesutan, Ioana; Razazian, Mehdi; Luong, Trang T. D.; Estepa, Misael; Pitigala, Lakmi; Henze, Laura A.; Obereigner, Jakob; Mitter, Gregor; Zickler, Daniel; Schuchardt, Mirjam; Deisl, Christine; Makridakis, Manousos; Gollmann-Tepekoeylue, Can; Pasch, Andreas; Cejka, Daniel; Suessner, Susanne; Antlanger, Marlies; Bielesz, Bernhard; Mueller, Mathias; Vlahou, Antonia; Holfeld, Johannes; Eckardt, Kai-Uwe; Voelkl, Jakob Share Save Share Save JAK-STAT signaling maintains homeostasis in T cells and macrophagesFortelny, Nikolaus; Farlik, Matthias; Fife, Victoria; Gorki, Anna-Dorothea; Lassnig, Caroline; Maurer, Barbara; Meissl, Katrin; Dolezal, Marlies; Boccuni, Laura; Geetha, Aarathy Ravi Sundar Jose; Akagha, Mojoyinola Joanna; Karjalainen, Anzhelika; Shoebridge, Stephen; Farhat, Asma; Mann, Ulrike; Jain, Rohit; Tikoo, Shweta; Zila, Nina; Esser-Skala, Wolfgang; Krausgruber, Thomas; Sitnik, Katarzyna; Penz, Thomas; Hladik, Anastasiya; Suske, Tobias; Zahalka, Sophie; Senekowitsch, Martin; Barreca, Daniele; Halbritter, Florian; Macho-Maschler, Sabine; Weninger, Wolfgang; Neubauer, Heidi A.; Moriggl, Richard; Knapp, Sylvia; Sexl, Veronika; Strobl, Birgit; Decker, Thomas; Mueller, Mathias; Bock, Christoph Share Save Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemiaSuske, Tobias; Sorger, Helena; Manhart, Gabriele; Ruge, Frank; Prutsch, Nicole; Zimmerman, Mark W.; Eder, Thomas; Abdallah, Diaaeldin I.; Maurer, Barbara; Wagner, Christina; Schoenefeldt, Susann; Spirk, Katrin; Pichler, Alexander; Pemovska, Tea; Schweicker, Carmen; Poeloeske, Daniel; Hubanic, Emina; Jungherz, Dennis; Mueller, Tony Andreas; Aung, Myint Myat Khine; Orlova, Anna; Pham, Ha Thi Thanh; Zimmel, Kerstin; Krausgruber, Thomas; Bock, Christoph; Mueller, Mathias; Dahlhoff, Maik; Boersma, Auke; Ruelicke, Thomas; Fleck, Roman; Araujo, Elvin Dominic de; Gunning, Patrick Thomas; Aittokallio, Tero; Mustjoki, Satu; Sanda, Takaomi; Hartmann, Sylvia; Grebien, Florian; Hoermann, Gregor; Haferlach, Torsten; Staber, Philipp Bernhard; Neubauer, Heidi Anne; Look, Alfred Thomas; Herling, Marco; Moriggl, Richard Share Save Transmission-selective muscle pathology induced by the active propagation of mutant huntingtin across the human neuromuscular synapseDinamarca, Margarita C.; Colombo, Laura; Brykczynska, Urszula; Grimm, Amandine; Fruh, Isabelle; Hossain, Imtiaz; Gabriel, Daniela; Eckert, Anne; Mueller, Matthias; Pecho-Vrieseling, Eline Share Save Share Save Regulation of NO Synthesis, Local Inflammation, and Innate Immunity to Pathogens by BET Family ProteinsWienerroither, Sebastian; Rauch, Isabella; Rosebrock, Felix; Jamieson, Amanda M.; Bradner, James; Muhar, Matthias; Zuber, Johannes; Mueller, Mathias; Decker, Thomas Share Save Noncanonical Effects of IRF9 in Intestinal Inflammation: More than Type I and Type III InterferonsRauch, Isabella; Rosebrock, Felix; Hainzl, Eva; Heider, Susanne; Majoros, Andrea; Wienerroither, Sebastian; Strobl, Birgit; Stockinger, Silvia; Kenner, Lukas; Mueller, Mathias; Decker, Thomas Share Save STAT1β Is Not Dominant Negative and Is Capable of Contributing to Gamma Interferon-Dependent Innate ImmunitySemper, Christian; Leitner, Nicole R.; Lassnig, Caroline; Parrini, Matthias; Mahlakoiv, Tanel; Rammerstorfer, Michael; Lorenz, Karin; Rigler, Doris; Mueller, Simone; Kolbe, Thomas; Vogl, Claus; Ruelicke, Thomas; Staeheli, Peter; Decker, Thomas; Mueller, Mathias; Strobl, Birgit Share Save Identification of marker genes to monitor residual iPSCs in iPSC-derived productsLemmens, Myriam; Perner, Juliane; Potgeter, Leon; Zogg, Michael; Thiruchelvam, Sineha; Mueller, Matthias; Doll, Thierry; Werner, Annick; Gilbart, Yoann; Couttet, Philippe; Martus, Hans-Jorg; Libertini, Silvana Share Save Stress signaling boosts interferon-induced gene transcription in macrophagesBoccuni, Laura; Podgorschek, Elke; Schmiedeberg, Moritz; Platanitis, Ekaterini; Traxler, Peter; Fischer, Philipp; Schirripa, Alessia; Novoszel, Philipp; Nebreda, Angel R.; Arthur, J. Simon C.; Fortelny, Nikolaus; Farlik, Matthias; Sexl, Veronika; Bock, Christoph; Sibilia, Maria; Kovarik, Pavel; Mueller, Mathias; Decker, Thomas Share Save Tyk2 is a tumor suppressor in colorectal cancerMoritsch, Stefan; Moedl, Bernadette; Scharf, Irene; Janker, Lukas; Zwolanek, Daniela; Timelthaler, Gerald; Casanova, Emilio; Sibilia, Maria; Mohr, Thomas; Kenner, Lukas; Herndler-Brandstetter, Dietmar; Gerner, Christopher; Mueller, Mathias; Strobl, Birgit; Eferl, Robert Share Save Receptor clustering and pathogenic complement activation in myasthenia gravis depend on synergy between antibodies with multiple subunit specificitiesRose, Natalie; Holdermann, Sebastian; Callegari, Ilaria; Kim, Hyein; Fruh, Isabelle; Kappos, Ludwig; Kuhle, Jens; Muller, Matthias; Sanderson, Nicholas S. R.; Derfuss, Tobias Share Save Share Save 
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