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S

Søren R. Paludan

aarhus university

77H-index
265Paper Count
2.7WCitation Count
Published Papers 149
Publication Date
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A genome-wide map of the genetic network in monocytes that regulates type I interferon induction by the cGAS-STING pathway
errScience Signaling
IF6.6
err2026-08-18
err0
PREAI
errEmil Aagaard Thomsen; Jian Zhao; Ryo Narita; Luther J. Davis; David Olagnier; Søren R. Paludan; Jacob Giehm Mikkelsen
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Double-Stranded DNA Sensing cGAS-STING Immune Signaling in a Rat Co-Culture Model of the Blood–Brain Barrier
errCell Biochemistry and Function
IF2.7
err2026-06-04
err0
errOAAI
errAndrás Harazin; Line S. Reinert; Parvez Alam; Lea Hoy; Annemette Boe Marnow; Janni Nielsen; Anna Lorentzen; Daniel E. Otzen; Søren R. Paludan; Morten S. Nielsen
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Lack of functional STING modulates immunity but does not protect dopaminergic neurons in the alpha-synuclein pre-formed fibrils Parkinson’s disease mouse model
errnpj Parkinson's Disease
IF8.2
err2025-12-11
err0
errOAAI
errIda H. Klæstrup; Line S. Reinert; Sara A. Ferreira; Johanne Lauritsen; Gitte U. Toft; Hjalte Gram; Poul H. Jensen; Søren R. Paludan; Marina Romero-Ramos
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errSave
Deleterious variants in the autophagy-related gene RB1CC1/FIP200 impair immunity to SARS-CoV-2
errNature Communications
IF15.7
err2025-11-27
err0
errOAAI
errLili Hu; Renee M. van der Sluis; Kennith Brian Castelino; Bao-Cun Zhang; Andreas Ronit; Thomas Zillinger; Marvin Werner; Sofie Eg Jørgensen; Anne Louise Hansen; Alice Pedersen; Ryo Narita; Line S. Reinert; Bettina Bundgaard; Christian K. Holm; Aurelie Cobat; Jean-Laurent Casanova; Fulvio Reggiori; Muriel Mari; Søren R. Paludan; Trine H. Mogensen
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The methyl-CpG-binding protein 2 inhibits cGAS-associated signaling
errNature Communications
IF15.7
err2025-11-07
err0
errOAAI
errHanane Chamma; Soumyabrata Guha; Roger Junior Eloiflin; Adeline Augereau; Pierre Le Hars; Moritz Schüssler; Yasmine Messaoud-Nacer; Mohammad Salma; Joe McKellar; Joanna Re; Morgane Chemarin; Arnaud Carrier; Michael A. Disyak; Clara Taffoni; Robin Charpentier; Zoé Husson; Emmanuel Valjent; Charlotte Andrieu-Soler; Eric Soler; Maria H. Christensen; Søren R. Paludan; Florian I. Schmidt; Daniela Tropea; Karim Majzoub; Isabelle K. Vila; Nadine Laguette
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errSave
Genetically heterozygous - transcriptionally homozygous IRF7 deficiency underlies herpesvirus CNS infections in humans
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2025-10-29
err0
PREAI
errWerner, Marvin; Wolff, Jonas Holst; Taft, Justin; Zillinger, Thomas; Hinke, Daniela M.; Barfod, Toke S.; de Keukeleere, Kerstin; Winzig, Franziska; Bundgaard, Bettina; Narita, Ryo; Skov, Thomas Wisbech; Jensen, Julie A.; Jorgensen, Sofie E.; Jorgensen, Charlotte S.; Skouboe, Morten K.; Lassauniere, Ria; de Boer, Joke H.; Jakobsen, Martin R.; Mikkelsen, Jacob G.; Bogunovic, Dusan; Paludan, Soren R.; van der Sluis, Renee M.; Mogensen, Trine H.
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errSave
Mapping Satellite Glial Cell Heterogeneity Reveals Distinct Spatial Organization and Implies Functional Diversity in the Dorsal Root Ganglion
errAdvanced Science
IF14.1
err2025-10-24
err0
errOAAI
errOle Andreas Ahlgreen; Mads Würgler Hansen; Jonas Baake; Thomas Engelbrecht Hybel; Rachele Rossi; Xin Lai; Ishwarya Sankaranarayanan; Johanne Amalie Pold; Lin Lin; Line Reinert; Søren Riis Paludan; Theodore John Price; Lone Tjener Pallesen; Christian Bjerggaard Vægter
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errSave
STING Signaling Deficiency Exacerbates Demyelination and Immune Infiltration in Focal EAE Lesions
errNEUROSCI
IF2
err2025-10-17
err0
PREAI
errMorch, Marlene T.; Reinert, Line S.; Benmamar-Badel, Anouk; Dubik, Magdalena; Burton, Mark; Thomassen, Mads; Kruse, Torben; Asgari, Nasrin; Paludan, Soren R.; Owens, Trevor; Khorooshi, Reza
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errSave
Role for NF-κB in herpes encephalitis pathology in mice genocopying an inborn error of IRF3-IFN immunity
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2025-10-09
err0
PREAI
errIdorn, Manja; Ding, Xiangning; Fruhwurth, Stefanie; Holste, Soren; Reinert, Line S.; Skoven, Christian S.; Turner-Stenstrom, Katarina; Schmitz, Alexander; Vendelbo, Mikkel H.; Ulhoi, Benedicte P.; Vizlin-Hodzic, Dzeneta; Wefelmeyer, Mona; Narita, Ryo; Kroese, Lona J.; Huijbers, Ivo J.; Mohlenberg, Michelle; Hollensen, Anne Kruse; Lai, Xin; Iversen, Marie B.; Hansen, Brian; Mogensen, Trine H.; Paludan, Soren R.
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errSave
STING signals to NF-κB from late endolysosomal compartments using IRF3 as an adaptor
errNature Immunology
IF27.6
err2025-09-19
err0
PREAI
errBao-cun Zhang; Alice Pedersen; Line S. Reinert; Ying Li; Ryo Narita; Manja Idorn; Lili Hu; Morten K. Skouboe; Sirui Li; Muyesier Maimaitili; Xiangning Ding; Yingying Cong; Jian Zhao; Marie-Louise Frémond; Kasper Mikkelsen; Zongliang Gao; Jin-rong Huang; Emil A. Thomsen; Jakob H. Mikkelsen; Rajan Venkatraman; Martin K. Thomsen; Marie B. Iversen; Sonia Assil; Ran Zhang; Linda Henneman; Martin R. Jakobsen; Claus Oxvig; Tina S. Dalgaard; Peter Møller; Angela Fago; Tobias Wang; Christian B. F. Andersen; Dominic De Nardo; Fulvio Reggiori; Jenny P.-Y. Ting; Jacob G. Mikkelsen; Rasmus O. Bak; Trine H. Mogensen; Pingwei Li; Søren R. Paludan
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errSave
Cholesterol in mRNA-Lipid Nanoparticles can be Replaced with the Synthetic Mycobacterial Monomycoloyl Glycerol Analogue MMG-1
errAdvanced Functional Materials
IF19
err2025-08-15
err0
errOAAI
errAbhijeet G. Lokras; Saahil S. Baghel; Rune F. Jensen; Aneesh Thakur; Henrik Franzyk; Oskar Thofte; Marco Herrera-Barrera; Madeleine Landry; Melike Ongun; Ahmad Tami; Marlene P. Thanthrige; Eva Callens; Corinne Beinat; Thomas Rades; Søren R. Paludan; Kristian Riesbeck; Ida Rosenkrands; Dennis Christensen; Gabriel K. Pedersen; Camilla Foged
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errSave
Early host defense against virus infections
errCELL REPORTS
IF6.9
err2024-12-01
err0
errOAAI
errPaludan, Soren R.; Pradeu, Thomas; Pichlmair, Andreas; Wray, K. Brad; Mikkelsen, Jacob Giehm; Olagnier, David; Mogensen, Trine H.
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Restriction factors regulating human herpesvirus infections
errTRENDS IN IMMUNOLOGY
IF13.9
err2024-09-01
err1
PREAI
errSerrero, Manutea C.; Paludan, Soren R.
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errSave
Mucosal IFNλ1 mRNA-based immunomodulation effectively reduces SARS-CoV-2 induced mortality in mice
errEMBO REPORTS
IF6.2
err2024-07-26
err0
errOAAI
errMacht, Anna; Huang, Yiqi; Reinert, Line S.; Grass, Vincent; Lohmer, Kristin; Prada, Elke Tatjana Aristizabal; Babel, Eveline; Semmler, Alexandra; Zhang, Wen; Wegner, Andrea; Lichtenegger-Hartl, Eva; Haas, Sonja; Hasenpusch, Guenther; Meyer, Steffen; Paludan, Soren R.; Pichlmair, Andreas; Rudolph, Carsten; Langenickel, Thomas
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Elucidating the function of STING in systemic lupus erythematosus through the STING Goldenticket mouse mutant
errSCIENTIFIC REPORTS
IF3.9
err2024-06-17
err2
errOAAI
errVejvisithsakul, Pichpisith Pierre; Thumarat, Chisanu; Leelahavanichkul, Asada; Hirankan, Nattiya; Pisitkun, Trairak; Paludan, Soren Riis; Pisitkun, Prapaporn
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errSave
Varicella zoster virus-induced autophagy in human neuronal and hematopoietic cells exerts antiviral activity
errJOURNAL OF MEDICAL VIROLOGY
IF4.6
err2024-05-28
err2
errOAAI
errHeinz, Johanna L.; Hinke, Daniela M.; Maimaitili, Muyesier; Wang, Jiayi; Sabli, Ira K. D.; Thomsen, Michelle; Farahani, Ensieh; Ren, Fanghui; Hu, Lili; Zillinger, Thomas; Grahn, Anna; von Hofsten, Joanna; Verjans, Georges M. G. M.; Paludan, Soren R.; Viejo-Borbolla, Abel; Sancho-Shimizu, Vanessa; Mogensen, Trine H.
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errSave
The STING inhibitor (ISD-017) reduces glomerulonephritis in 129.B6.Fcgr2b-deficient mice
errSCIENTIFIC REPORTS
IF3.9
err2024-05-14
err1
errOAAI
errAlee, Isara; Chantawichitwong, Papasara; Leelahavanichkul, Asada; Paludan, Soren R.; Pisitkun, Trairak; Pisitkun, Prapaporn
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errSave
Using Reference Publication Year Spectroscopy (RPYS) to analyze the research and publication culture in immunology
errSCIENTOMETRICS
IF3.5
err2024-05-02
err1
errOAAI
errWray, K. Brad; Paludan, Soren R.; Bornmann, Lutz; Haunschild, Robin
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errSave
HSV-1 employs UL56 to antagonize expression and function of cGAMP channels
errCELL REPORTS
IF6.9
err2024-05-01
err5
errOAAI
errBlest, Henry T. W.; Redmond, Alexander; Avissar, Jed; Barker, Jake; Bridgeman, Anne; Fowler, Gerissa; Chauveau, Lise; Hertzog, Jonny; Vendrell, Iolanda; Fischer, Roman; Iversen, Marie B.; Jing, Lichen; Koelle, David M.; Paludan, Soren R.; Kessler, Benedikt M.; Crump, Colin M.; Research, Jan Rehwinkel
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Cholesterol-binding motifs in STING that control endoplasmic reticulum retention mediate anti-tumoral activity of cholesterol-lowering compounds
errNATURE COMMUNICATIONS
IF15.7
err2024-03-29
err2
errOAAI
errZhang, Bao-cun; Laursen, Marlene F.; Hu, Lili; Hazrati, Hossein; Narita, Ryo; Jensen, Lea S.; Hansen, Aida S.; Huang, Jinrong; Zhang, Yan; Ding, Xiangning; Muyesier, Maimaitili; Nilsson, Emil; Banasik, Agnieszka; Zeiler, Christina; Mogensen, Trine H.; Etzerodt, Anders; Agger, Ralf; Johannsen, Mogens; Kofod-Olsen, Emil; Paludan, Soren R.; Jakobsen, Martin R.
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Research Directions

No research directions
Co-authors
Cooperation Journals
C
Craig B. Thompson
H-index: 206 · Papers: 767
H
Henrik Zetterberg
H-index: 190 · Papers: 3.7K
J
Jean‐Laurent Casanova
H-index: 171 · Papers: 1.4K
C
Christian Weber
H-index: 160 · Papers: 1.8K
B
Bryan Williams
H-index: 151 · Papers: 1.6K
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