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J

John S. Tsang

biohub

44H-index
165Paper Count
1.1WCitation Count
Published Papers 73
Publication Date
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Fifteen challenges for generative AI applications to cell biology
errCell
IF42.5
err2026-08-17
err0
errOAAI
errLeo Dupire; Aly A. Khan; Theofanis Karaletsos; Shana Kelley; Emma Lundberg; Jian Ma; Evan Paull; Stephen R. Quake; Raul Rabadan; Cassius Rowan; Peter Sims; Sohail Tavazoie; John S. Tsang; Mingxuan Zhang; Andrea Califano
errShare
errSave
Immune aging biomarkers for clinical trials
errNature Medicine
IF50
err2026-07-03
err0
PREAI
errAndrea Cipriano; Jamie Justice; Jesse R. Poganik; Mahdi Moqri; Omar O. Abudayyeh; Jonathan Gootenberg; Laura Haynes; Yotam Levin; Daniel E. Martin-Herranz; Arne N. Akbar; Joan Mannick; Graham Pawelec; Shai S. Shen-Orr; John Tsang; Wolfgang Wagner; Miriam Merad; Sacha Gnjatic; Alfred Gellhorn; Michael J. Corley; George A. Kuchel; Luigi Ferrucci; David Furman; Chiara M. S. Herzog
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errSave
Innate immune responsiveness predicts enhanced cellular immunity and symptomatic disease after controlled human influenza infection
errNature Medicine
IF50
err2026-07-01
err0
errOAAI
errLoukas Papargyris; Jiayun Xu; Claire Broderick; Ao Huang; Trupti Gore; Arnold Reynaldi; Pete Dayananda; Ashley M. Collins; Stephanie Ascough; Nathan Wong; Jon Guy; Jihye Song; Satwik Kar; Emma Bergstrom; Lydia Slater; Zoe Gardener; Suzanna Paterson; Mahdi Moradi Marjaneh; Samuel J. Nichols; Victoria J. Wright; Min Kyu Park; Richard McKendry; Brad Nicholson; Micah McClain; Thomas W. Burke; Helen Wagstaffe; Jelle Klein; Michael Levin; Alba Grifoni; Christopher W. Woods; Miles P. Davenport; John S. Tsang; Benny Chain; Myrsini Kaforou; Christopher Chiu
errShare
errSave
SARS-CoV-2 infection and vaccination elicit distinct pharyngeal mucosal B cell responses in children
errNature Communications
IF15.7
err2026-05-22
err0
errOAAI
errQin Xu; Lihong Shi; Can Liu; Juraj Kabat; Hengameh Behzadpour; Lela Kardava; Tovah E. Markowitz; Margery Smelkinson; Kenneth B. Hoehn; Clarisa M. Buckner; Dominic P. Golec; Lorenza Bellusci; Gabrielle Grubbs; Sara Pourhashemi; Juanjie Tang; Asya Khleborodova; Martha Kirby; Rachel Sparks; Andrew J. Martins; John S. Tsang; Susan Moir; Surender Khurana; Pamela Mudd; Pamela L. Schwartzberg; Kalpana Manthiram
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errSave
Pre-existing and early cellular immune factors correlate with functionally complete protection against primary controlled human SARS-CoV-2 infection
errNature Communications
IF15.7
err2025-12-07
err0
errOAAI
errHelen R. Wagstaffe; Ryan S. Thwaites; Jasmin K. Sidhu; Rik G. H. Lindeboom; Lorenz Kretschmer; Kaylee B. Worlock; Lisa M. Dratva; Ao Huang; Stephanie Ascough; Loukas Papargyris; Richard McKendry; Ashley M. Collins; Jiayun Xu; Nana-Marie Lemm; Ben Killingley; Mariya Kalinova; Alex Mann; Andrew Catchpole; Leo Swadling; John S. Tsang; Mala K. Maini; Mahdad Noursadeghi; Marko Z. Nikolić; Sarah A. Teichmann; Peter J. M. Openshaw; Christopher Chiu
errShare
errSave
AI immunologists are here: Are they ready for prime time?
errScience Immunology
IF16.3
err2025-12-05
err0
PREAI
errJacob Kim; Ao Huang; John S. Tsang
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errSave
Longitudinal single cell multi-omic profiling of Nicaraguan children reveals trajectories of pediatric immune development and variation 2840
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errBichmann, Leon; Rachmaninoff, Nicholas; Popper, Stephen; Bansal, Neha; Koroleva, Galina; Liu, Can; Martins, Andrew; Gresh, Lionel; Zambrana, Jose Victor; Gordon, Aubree; Johnson, Philip; Kuan, Guillermina; Balmaseda, Angel; Harris, Eva; Tsang, John
errShare
errSave
SARS-CoV-2 mRNA vaccination elicits distinct pharyngeal mucosal B cell responses in children compared to infection
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errXu, Qin; Mudd, Pamela; Kardava, Lela; Behzadpour, Hengameh; Bellusci, Lorenza; Grubbs, Gabrielle; Pourhashemi, Sara; Tang, Juanjie; Liu, Can; Newman, Daniel; Shi, Lihong; Milanez-Almeida, Pedro; Tsang, John; Moir, Susan; Khurana, Surender; Schwartzberg, Pamela L.; Manthiram, Kalpana
errShare
errSave
SARS-CoV-2 induced immune perturbations in infants vary with disease severity and differ from adults' responses
errNATURE COMMUNICATIONS
IF15.7
err2025-05-16
err0
errOAAI
errNehar-Belaid, Djamel; Mejias, Asuncion; Xu, Zhaohui; Marches, Radu; Yerrabelli, Rushil; Chen, Guo; Mertz, Sara; Ye, Fang; Sanchez, Pablo J.; Tsang, John S.; Aydillo, Teresa; Miorin, Lisa; Cupic, Anastasija; Garcia-Sastre, Adolfo; Ucar, Duygu; Banchereau, Jacques F.; Pascual, Virginia; Ramilo, Octavio
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errSave
Systems Human Immunology and AI: Immune Setpoint and Immune Health
errANNUAL REVIEW OF IMMUNOLOGY
IF33.3
err2025-04-25
err0
PREAI
errLei, Yona; Tsang, John S.
errShare
errSave
A single-cell atlas of circulating immune cells over the first 2 months of age in extremely premature infants
errScience Translational Medicine
IF14.6
err2025-03-05
err0
PREAI
errOluwabunmi Olaloye; Weihong Gu; Arne Gehlhaar; Burhanuddin Sabuwala; Chino K. Eke; Yujia Li; Tessa Kehoe; Rohit Farmer; Gisela Gabernet; Carrie L. Lucas; John S. Tsang; Saquib A. Lakhani; Sarah N. Taylor; George Tseng; Steven H. Kleinstein; Liza Konnikova
errShare
errSave
Acute and persistent responses after H5N1 vaccination in humans
errCELL REPORTS
IF6.9
err2024-09-01
err0
errOAAI
errApps, Richard; Biancotto, Angelique; Candia, Julian; Kotliarov, Yuri; Perl, Shira; Cheung, Foo; Farmer, Rohit; Mule, Matthew P.; Rachmaninoff, Nicholas; Chen, Jinguo; Martins, Andrew J.; Shi, Rongye; Zhou, Huizhi; Bansal, Neha; Schum, Paula; Olnes, Matthew J.; Milanez-Almeida, Pedro; Han, Kyu Lee; Sellers, Brian; Cortese, Mario; Hagan, Thomas; Rouphael, Nadine; Pulendran, Bali; King, Lisa; Manischewitz, Jody; Khurana, Surender; Golding, Hana; van der Most, Robbert G.; Dickler, Howard B.; Germain, Ronald N.; Schwartzberg, Pamela L.; Tsang, John S.
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errSave
Teplizumab induces persistent changes in the antigen- specific repertoire in individuals at risk for type 1 diabetes
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2024-08-13
err0
errOAAI
errLledo-Delgado, Ana; Preston-Hurlburt, Paula; Currie, Sophia; Clark, Pamela; Linsley, Peter S.; Long, S. Alice; Liu, Can; Koroleva, Galina; Martins, Andrew J.; Tsang, John S.; Herold, Kevan C.
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errSave
Preliminary Findings From the Dynamics of the Immune Responses to Repeat Influenza Vaccination Exposures (DRIVE I) Study: A Randomized Controlled Trial
errCLINICAL INFECTIOUS DISEASES
IF7.3
err2024-07-23
err1
errOAAI
errCowling, Benjamin J.; Wong, Sook-San; Santos, Jefferson J. S.; Touyon, Lisa; Ort, Jordan T.; Ye, Naiqing; Kwok, Natalie K. M.; Ho, Faith; Cheng, Samuel M. S.; Ip, Dennis K. M.; Peiris, Malik; Webby, Richard J.; Wilson, Patrick C.; Valkenburg, Sophie A.; Tsang, John S.; Leung, Nancy H. L.; Hensley, Scott E.; Cobey, Sarah
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errSave
Licensed H5N1 vaccines generate cross-neutralizing antibodies against highly pathogenic H5N1 clade 2.3.4.4b influenza virus
errNATURE MEDICINE
IF50
err2024-07-16
err3
PREAI
errKhurana, Surender; King, Lisa R.; Manischewitz, Jody; Posadas, Olivia; Mishra, Ashish K.; Liu, Dongxiao; Beigel, John H.; Rappuoli, Rino; Tsang, John S.; Golding, Hana
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errSave
A unified metric of human immune health
errNATURE MEDICINE
IF50
err2024-07-03
err3
errOAAI
errSparks, Rachel; Rachmaninoff, Nicholas; Lau, William W.; Hirsch, Dylan C.; Bansal, Neha; Martins, Andrew J.; Chen, Jinguo; Liu, Candace C.; Cheung, Foo; Failla, Laura E.; Biancotto, Angelique; Fantoni, Giovanna; Sellers, Brian A.; Chawla, Daniel G.; Howe, Katherine N.; Mostaghimi, Darius; Farmer, Rohit; Kotliarov, Yuri; Calvo, Katherine R.; Palmer, Cindy; Daub, Janine; Foruraghi, Ladan; Kreuzburg, Samantha; Treat, Jennifer D.; Urban, Amanda K.; Jones, Anne; Romeo, Tina; Deuitch, Natalie T.; Moura, Natalia Sampaio; Weinstein, Barbara; Moir, Susan; Ferrucci, Luigi; Barron, Karyl S.; Aksentijevich, Ivona; Kleinstein, Steven H.; Townsley, Danielle M.; Young, Neal S.; Frischmeyer-Guerrerio, Pamela A.; Uzel, Gulbu; Pinto-Patarroyo, Gineth Paola; Cudrici, Cornelia D.; Hoffmann, Patrycja; Stone, Deborah L.; Ombrello, Amanda K.; Freeman, Alexandra F.; Zerbe, Christa S.; Kastner, Daniel L.; Holland, Steven M.; Tsang, John S.
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errSave
Integrating population and single-cell variations in vaccine responses identifies a naturally adjuvanted human immune setpoint
errIMMUNITY
IF26.3
err2024-05-01
err4
PREAI
errMule, Matthew P.; Martins, Andrew J.; Cheung, Foo; Farmer, Rohit; Sellers, Brian A.; Quiel, Juan A.; Jain, Arjun; Kotliarov, Yuri; Bansal, Neha; Chen, Jinguo; Schwartzberg, Pamela L.; Tsang, John S.
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errSave
Human transcriptional signature of protection after Plasmodium falciparum immunization and infectious challenge via mosquito bites
errHUMAN VACCINES & IMMUNOTHERAPEUTICS
IF3.5
err2023-11-27
err1
errOAAI
errMura, Marie; Misganaw, Burook; Gautam, Aarti; Robinson, Tanisha; Chaudhury, Sidhartha; Bansal, Neha; Martins, Andrew J.; Tsang, John; Hammamieh, Rasha; Bergmann-Leitner, Elke
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errSave
Characterization of the antispike IgG immune response to COVID-19 vaccines in people with a wide variety of immunodeficiencies
errSCIENCE ADVANCES
IF12.5
err2023-10-13
err5
errOAAI
errZendt, Mackenzie; Bustos Carrillo, Fausto A.; Kelly, Sophie; Saturday, Taylor; Degrange, Maureen; Ginigeme, Anita; Wu, Lurline; Callier, Viviane; Ortega-Villa, Ana; Faust, Mondreakest; Chang-Rabley, Emma; Bugal, Kara; Kenney, Heather; Khil, Pavel; Youn, Jung-Ho; Osei, Gloria; Regmi, Pravesh; Anderson, Victoria; Bosticardo, Marita; Daub, Janine; Dimaggio, Thomas; Kreuzburg, Samantha; Pala, Francesca; Pfister, Justina; Treat, Jennifer; Ulrick, Jean; Karkanitsa, Maria; Kalish, Heather; Kuhns, Douglas B.; Priel, Debra L.; Fink, Danielle L.; Tsang, John S.; Sparks, Rachel; Uzel, Gulbu; Waldman, Meryl A.; Zerbe, Christa S.; Delmonte, Ottavia M.; Bergerson, Jenna R. E.; Das, Sanchita; Freeman, Alexandra F.; Lionakis, Michail S.; Sadtler, Kaitlyn; van Doremalen, Neeltje; Munster, Vincent; Notarangelo, Luigi D.; Holland, Steven M.; Ricotta, Emily E.
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errSave
Systems immunology of regulatory T cells: can one circuit explain it all?
errTRENDS IN IMMUNOLOGY
IF13.9
err2023-10-01
err6
errOAAI
errTripathi, Shubham; Tsang, John S.; Park, Kyemyung
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Luigi Ferrucci
H-index: 237 · Papers: 2.6K
A
Anthony S. Fauci
H-index: 185 · Papers: 1.1K
P
Phillip A. Sharp
H-index: 173 · Papers: 638
M
Mark M. Davis
H-index: 173 · Papers: 988
M
Michael Diamond
H-index: 160 · Papers: 1.5K
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