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A PI3Kd-Foxo1-FasL signaling amplification loop rewires CD4+T helper cell signaling, differentiation and epigenetic remodeling Golec, Dominic P.; Gazzinelli-Guimaraes, Pedro; Chauss, Daniel; Nagashima, Hiroyuki; Yu, Kang; Hill, Tom; Cannons, Jennifer L.; Perry, Jillian; Joshi, Ilin; Pereira, Nicolas; Silva Oliveira, Fabricio Marcus; Cruz, Anthony C.; Druey, Kirk M.; Lack, Justin B.; Nutman, Thomas B.; Villarino, Alejandro V.; O'Shea, John J.; Afzali, Behdad; Schwartzberg, Pamela L. Share Save
Cell-autonomous complement C3 activity in prostate epithelial cells suppresses malignant transformation through tonic restrain of the MYC-tumorigenesis program Kunz, Natalia; Bibby, Jack A.; Merle, Nicolas S.; Kartal, Sumeyra; Yamamoto, Hidekazu; Wang, Luopin; Taj, Md; Ma, Jianping; Kolev, Martin, V; Lotscher, Jonas; Kellerhals, Tamara; Balmer, Maria L.; Chandra, Ash; Hess, Christoph; Afzali, Behdad; Dasgupta, Prokar; West, Erin E.; Sowalsky, Adam G.; Kemper, Claudia Share Save
Peptide-mediated modulation of complement-like CD109 boosts T cell anti-tumor responses Merle, Nicolas S.; Kolev, Martin V.; Ding, Jienyu; West, Erin; Phadke, Ira; Rahman, Jubayer; Bibby, Jack; Yan, Bingyue; Kazemian, Majid; Nguyen, Rosa; Afzali, Behdad; Biertuempfel, Christian; Mizuno, Naoko; Kemper, Claudia Share Save
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A deep intronic splice-altering AIRE variant causes APECED syndrome through antisense oligonucleotide-targetable pseudoexon inclusion Ochoa, Sebastian; Hsu, Amy P.; Oler, Andrew J.; Kumar, Dhaneshwar; Chauss, Daniel; van Hamburg, Jan Piet; van Laar, Gustaaf G.; Oikonomou, Vasileios; Ganesan, Sundar; Ferre, Elise M. N.; Schmitt, Monica M.; Dimaggio, Tom; Barber, Princess; Constantine, Gregory M.; Rosen, Lindsey B.; Auwaerter, Paul G.; Gandhi, Bhumika; Miller, Jennifer L.; Eisenberg, Rachel; Rubinstein, Arye; Schussler, Edith; Balliu, Erjola; Shashi, Vandana; Neth, Olaf; Olbrich, Peter; Le, Kim My; Mamia, Nanni; Laakso, Saila; Nevalainen, Pasi I.; Groenholm, Juha; Seppaenen, Mikko R. J.; Boon, Louis; Uzel, Gulbu; Franco, Luis M.; Heller, Theo; Winer, Karen K.; Ghosh, Rajarshi; Seifert, Bryce A.; Walkiewicz, Magdalena; Notarangelo, Luigi D.; Zhou, Qing; Askentijevich, Ivona; Gahl, William; Dalgard, Cliffton L.; Perera, Lalith; Afzali, Behdad; Tas, Sander W.; Holland, Steven M.; Lionakis, Michail S. Share Save
Unbiased discovery of cancer pathways and therapeutics using Pathway Ensemble Tool and Benchmark Wang, Luopin; Pattnaik, Aryamav; Sahoo, Subhransu Sekhar; Stone, Ella G.; Zhuang, Yuxin; Benton, Annaleigh; Tajmul, Md; Chakravorty, Srishti; Dhawan, Deepika; Nguyen, My An; Sirit, Isabella; Mundy, Kyle; Ricketts, Christopher J.; Hadisurya, Marco; Baral, Garima; Tinsley, Samantha L.; Anderson, Nicole L.; Hoda, Smriti; Briggs, Scott D.; Kaimakliotis, Hristos Z.; Allen-Petersen, Brittany L.; Tao, W. Andy; Linehan, W. Marston; Knapp, Deborah W.; Hanna, Jason A.; Olson, Matthew R.; Afzali, Behdad; Kazemian, Majid Share Save
Prostate epithelial cell intrinsic C3 represses MYC-driven tumorigenesis Kunz, Natalia; Bobby, Jack; Yamamoto, Hidekazu; Merle, Nicolas; Wang, Luopin; Taj, Md; Ma, Jianping; Kolev, Martin; Loetscher, Jonas; Kellerhals, Tamara; Balmer, Maria; Chandra, Ash; Hess, Christoph; Afzali, Behdad; Kazemian, Majid; Dasgupta, Prokar; West, Erin Share Save
Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection West, Erin E.; Merle, Nicolas S.; Kaminski, Marcin M.; Palacios, Gustavo; Kumar, Dhaneshwar; Wang, Luopin; Bibby, Jack A.; Overdahl, Kirsten; Jarmusch, Alan K.; Freeley, Simon; Lee, Duck-Yeon; Thompson, J. Will; Yu, Zu-Xi; Taylor, Naomi; Sitbon, Marc; Green, Douglas R.; Bohrer, Andrea; Mayer-Barber, Katrin D.; Afzali, Behdad; Kazemian, Majid; Scholl-Buergi, Sabine; Karall, Daniela; Huemer, Martina; Kemper, Claudia Share Save
Successful Treatment of Paecilomyces variotii Pneumonia and Lupus Nephritis With Posaconazole-Cyclophosphamide Co-administration Without Drug Interaction-Induced Toxicity Pechacek, Joseph; Webb, Taura; Ferre, Elise M. N.; Schmitt, Monica M.; DiMaggio, Thomas; Kobrin, Dale; Rajasimhan, Suraj; Colton, Ben; Lewis, Russell E.; Andes, David; Herrera, Alejandro; Hammoud, Dima; Seyedmousavi, Seyedmojtaba; Hasni, Sarfaraz; Bolanos, Jonathan; Afzali, Behdad; Lionakis, Michail S. Share Save
Transcription factor EGR2 controls homing and pathogenicity of TH17 cells in the central nervous system Gao, Yuanyuan; Wang, Yan; Chauss, Daniel; Villarino, Alejandro V.; Link, Verena M.; Nagashima, Hiroyuki; Spinner, Camille A.; Koparde, Vishal N.; Bouladoux, Nicolas; Abers, Michael S.; Break, Timothy J.; Chopp, Laura B.; Park, Jung-Hyun; Zhu, Jinfang; Wiest, David L.; Leonard, Warren J.; Lionakis, Michail S.; O'Shea, John J.; Afzali, Behdad; Belkaid, Yasmine; Lazarevic, Vanja Share Save
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CD4 T cell intrinsic arginase 1 controls the kinetics of Th1 induction and contraction West, Erin E.; Merle, Nicolas S.; Kaminski, Marcin M.; Palacios, Gustavo; Kumar, Dhaneshwar; Wang, Luopin; Overdahl, Kristen; Jarmusch, Alan K.; Freeley, Simon; Taylor, Naomi; Sitbon, Marc; Green, Douglas R.; Bohrer, Andrea; Mayer-Barber, Katrin; Afzali, Behdad; Kazemian, Majid; Scholl-Buergi, Sabine; Karall, Daniela; Huemer, Martina; Kemper, Claudia Share Save
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A comprehensive single cell data analysis of lymphoblastoid cells reveals the role of super-enhancers in maintaining EBV latency Yan, Bingyu; Wang, Chong; Chakravorty, Srishti; Zhang, Zonghao; Kadadi, Simran D.; Zhuang, Yuxin; Sirit, Isabella; Hu, Yonghua; Jung, Minwoo; Sahoo, Subhransu S.; Wang, Luopin; Shao, Kunming; Anderson, Nicole L.; Trujillo-Ochoa, Jorge L.; Briggs, Scott D.; Liu, Xing; Olson, Matthew R.; Afzali, Behdad; Zhao, Bo; Kazemian, Majid Share Save
A central role for STAT5 in the transcriptional programing of T helper cell metabolism Villarino, Alejandro V.; Laurence, Arian D. J.; Davisi, Fred P.; Nivelo, Luis; Brooks, Stephen R.; Sun, Hong-Wei; Jiang, Kan; Afzali, Behdad; Frasca, Daniela; Hennighausen, Lothar; Kanno, Yuka; O'Shea, John J. Share Save
Systematic single-cell pathway analysis to characterize early T cell activation Bibby, Jack A.; Agarwal, Divyansh; Freiwald, Tilo; Kunz, Natalia; Merle, Nicolas S.; West, Erin E.; Singh, Parul; Larochelle, Andre; Chinian, Fariba; Mukherjee, Somabha; Afzali, Behdad; Kemper, Claudia; Zhang, Nancy R. Share Save
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