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Rejuvenation of tumor-infiltrating lymphocytes (TIL): A novel strategy to revitalize TIL antitumor function for cell therapy Vizcardo, Raul; Huang, Yin; Fioravanti, Jessica; Maeda, Takuya; Tamaoki, Naritaka; Yamazaki, Yasuhiro; Kutlu, Burak; Bahl, Kriti; Wang, Biao; Zhong, Zheng; Potluri, Shobha; Restifo, Nicholas P.; Lee, Gary Share Save
Self-organized yolk sac-like organoids allow for scalable generation of multipotent hematopoietic progenitor cells from induced pluripotent stem cells Tamaoki, Naritaka; Siebert, Stefan; Maeda, Takuya; Ha, Ngoc-Han; Good, Meghan L.; Huang, Yin; Vodnala, Suman K.; Haro-Mora, Juan J.; Uchida, Naoya; Tisdale, John F.; Sweeney, Colin L.; Choi, Uimook; Brault, Julie; Koontz, Sherry; Malech, Harry L.; Yamazaki, Yasuhiro; Isonaka, Risa; Goldstein, David S.; Kimura, Masaki; Takebe, Takanori; Zou, Jizhong; Stroncek, David F.; Robey, Pamela G.; Kruhlak, Michael J.; Restifo, Nicholas P.; Vizcardo, Raul Share Save
THE EPI-RTM TECHNOLOGY PRODUCES A POLYCLONAL TIL PRODUCT (LYL845) WITH A GREATER EXPANSION SUCCESS RATE ACROSS HOT AND COLD TUMORS, IMPROVED PRODUCT PHENOTYPE, AND MAINTENANCE OF TCR DIVERSITY Patel, Yogin; Harris, Benjamin; Bedard, Melissa; Kritikou, Joanna; Casas, Meritxell Galindo; Harms, Carson; DeFrancesco, Melissa; Sundar, Purnima; Restifo, Nicholas; Lee, Gary; Potluri, Shobha; Vodnala, Suman Kumar Share Save
Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade Palmer, Douglas C.; Webber, Beau R.; Patel, Yogin; Johnson, Matthew J.; Kariya, Christine M.; Lahr, Walker S.; Parkhurst, Maria R.; Gartner, Jared J.; Prickett, Todd D.; Lowery, Frank J.; Kishton, Rigel J.; Gurusamy, Devikala; Franco, Zulmarie; Vodnala, Suman K.; Diers, Miechaleen D.; Wolf, Natalie K.; Slipek, Nicholas J.; McKenna, David H.; Sumstad, Darin; Viney, Lydia; Henley, Tom; Burckstummer, Tilmann; Baker, Oliver; Hu, Ying; Yan, Chunhua; Meerzaman, Daoud; Padhan, Kartik; Lo, Winnie; Malekzadeh, Parisa; Jia, Li; Deniger, Drew C.; Patel, Shashank J.; Robbins, Paul F.; McIvor, R. Scott; Choudhry, Modassir; Rosenberg, Steven A.; Moriarity, Branden S.; Restifo, Nicholas P. Share Save
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Cancer genes disfavoring T cell immunity identified via integrated systems approach Kishton, Rigel J.; Patel, Shashank J.; Decker, Amy E.; Vodnala, Suman K.; Cam, Maggie; Yamamoto, Tori N.; Patel, Yogin; Sukumar, Madhusudhanan; Yu, Zhiya; Ji, Michelle; Henning, Amanda N.; Gurusamy, Devikala; Palmer, Douglas C.; Stefanescu, Roxana A.; Girvin, Andrew T.; Lo, Winifred; Pasetto, Anna; Malekzadeh, Parisa; Deniger, Drew C.; Wood, Kris C.; Sanjana, Neville E.; Restifo, Nicholas P. Share Save
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Multiply restimulated human thymic regulatory T cells express distinct signature regulatory T-cell transcription factors without evidence of exhaustion Hippen, Keli L.; Furlan, Scott N.; Roychoudhuri, Rahul; Wang, Ena; Zhang, Yigang; Osborn, Mark J.; Merkel, Sarah C.; Hani, Sophia; MacMillan, Margaret L.; Cichocki, Frank; Miller, Jeffrey S.; Wagner, John E.; Restifo, Nicholas P.; Kean, Leslie S.; Blazar, Bruce R. Share Save
Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy (vol 26, pg 781, 2020) Perez-Guijarro, Eva; Yang, Howard H.; Araya, Romina E.; El Meskini, Rajaa; Michael, Helen T.; Vodnala, Suman Kumar; Marie, Kerrie L.; Smith, Cari; Chin, Sung; Lam, Khiem C.; Thorkelsson, Andres; Iacovelli, Anthony J.; Kulaga, Alan; Fon, Anyen; Michalowski, Aleksandra M.; Hugo, Willy; Lo, Roger S.; Restifo, Nicholas P.; Sharan, Shyam K.; Van Dyke, Terry; Goldszmid, Romina S.; Ohler, Zoe Weaver; Lee, Maxwell P.; Day, Chi-Ping; Merlino, Glenn Share Save
Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas Dersh, Devin; Phelan, James D.; Gumina, Megan E.; Wang, Boya; Arbuckle, Jesse H.; Holly, Jaroslav; Kishton, Rigel J.; Markowitz, Tovah E.; Seedhom, Mina O.; Fridlyand, Nathan; Wright, George W.; Huang, Da Wei; Ceribelli, Michele; Thomas, Craig J.; Lack, Justin B.; Restifo, Nicholas P.; Kristie, Thomas M.; Staudt, Louis M.; Yewdell, Jonathan W. Share Save
STING agonist promotes CAR T cell trafficking and in breast cancer Xu, Nuo; Palmer, Douglas C.; Robeson, Alexander C.; Shou, Peishun; Bommiasamy, Hemamalini; Laurie, Sonia J.; Willis, Caryn; Dotti, Gianpietro; Vincent, Benjamin G.; Restifo, Nicholas P.; Serody, Jonathan S. Share Save
Definitive hematopoietic stem/progenitor cells from human embryonic stem cells through serum/feeder-free organoid-induced differentiation (vol 11, 493, 2020) Demirci, Selami; Haro-Mora, Juan J.; Leonard, Alexis; Drysdale, Claire; Malide, Daniela; Keyvanfar, Keyvan; Essawi, Khaled; Vizcardo, Raul; Tamaoki, Naritaka; Restifo, Nicholas P.; Tisdale, John F.; Uchida, Naoya Share Save
Definitive hematopoietic stem/progenitor cells from human embryonic stem cells through serum/feeder-free organoid-induced differentiation Demirci, Selami; Haro-Mora, Juan J.; Leonard, Alexis; Drysdale, Claire; Malide, Daniela; Keyvanfar, Keyvan; Essawi, Khaled; Vizcardo, Raul; Tamaoki, Naritaka; Restifo, Nicholas P.; Tisdale, John F.; Uchida, Naoya Share Save
TARGETING THE APICAL INTRACELLULAR CHECKPOINT CISH UNLEASHES T CELL NEOANTIGEN REACTIVITY AND EFFECTOR PROGRAM Palmer, Douglas; Webber, Beau; Patel, Yogin; Johnson, Matthew; Kariya, Christine; Lahr, Walker; Parkhurst, Maria; Gartner, Jared; Prickett, Todd; Lowery, Frank; Kishton, Rigel; Gurusamy, Devikala; Franco, Zulmarie; Vodnala, Suman; Diers, Miechaleen; Wolf, Natalie; Slipek, Nicholas; McKenna, David; Sumstad, Darin; Viney, Lydia; Henley, Tom; Burckstummer, Tilmann; Baker, Oliver; Hu, Ying; Yan, Chunhua; Meerzaman, Daoud; Padhan, Kartik; Lo, Winnie; Malekzadeh, Parisa; Jia, Li; Deniger, Drew; Patel, Shashank; Robbins, Paul; McIvor, R. Scott; Choudhry, Modassir; Rosenberg, Steven; Moriarity, Branden; Restifo, Nicholas Share Save
Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy Perez-Guijarro, Eva; Yang, Howard H.; Araya, Romina E.; El Meskini, Rajaa; Michael, Helen T.; Vodnala, Suman Kumar; Marie, Kerrie L.; Smith, Cari; Chin, Sung; Lam, Khiem C.; Thorkelsson, Andres; Iacovelli, Anthony J.; Kulaga, Alan; Fon, Anyen; Michalowski, Aleksandra M.; Hugo, Willy; Lo, Roger S.; Restifo, Nicholas P.; Sharan, Shyam K.; Van Dyke, Terry; Goldszmid, Romina S.; Ohler, Zoe Weaver; Lee, Maxwell P.; Day, Chi-Ping; Merlino, Glenn Share Save
Identification of Small Molecule Enhancers of Immunotherapy for Melanoma Dextras, Christopher; Dashnyam, Myagmarjav; Griner, Lesley A. Mathews; Sundaresan, Janani; Chim, Bryan; Yu, Zhiya; Vodnala, Suman; Lee, Chyi-Chia Richard; Hu, Xin; Southall, Noel; Marugan, Juan J.; Jadhav, Ajit; Restifo, Nicholas P.; Acquavella, Nicolas; Ferrer, Marc; Singh, Anju Share Save
Antigen Experienced T Cells from Peripheral Blood Recognize p53 Neoantigens Malekzadeh, Parisa; Yossef, Rami; Cafri, Gal; Paria, Biman C.; Lowery, Frank J.; Jafferji, Mohammad; Good, Meghan L.; Sachs, Abraham; Copeland, Amyr.; Kim, Sanghyun P.; Kivitz, Scott; Parkhurst, Maria R.; Robbins, Paul F.; Ray, Satyajit; Xi, Liqiang; Raffeld, Mark; Yu, Zhiya; Restifo, Nicholas P.; Somerville, Robert P. T.; Rosenberg, Steven A.; Deniger, Drew C. Share Save
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