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Christine E. Brown

Beckman Research Institute of the City of Hope

65H-index
419Paper Count
1.6WCitation Count
Published Papers 120
Publication Date
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A phase 1 trial of CD123-directed chimeric antigen receptor T-cell therapy in adults with relapsed/refractory acute myeloid leukemia or blastic plasmacytoid dendritic cell neoplasm
errJournal of Hematology & Oncology
IF40.4
err2026-08-07
err0
errOAAI
errLihua E. Budde; Marissa M. Del Real; Joo Song; Tracey Stiller; Yan Wang; Ahmed Aribi; Karamjeet Sandhu; Ryotaro Nakamura; Emanuela C. Marcucci; Jian J. Wu; Kenneth Ng; Mary C. Clark; Brent Wood; Jamie R. Wagner; Jinny Paul; Christine E. Brown; Anthony Stein; Guido Marcucci; M. Suzette Blanchard; Joycelynne Palmer; Stephen J. Forman
errShare
errSave
Targeting mitotic kinesin KIF20A: A differentiation-based therapeutic strategy for glioblastoma stem/progenitor cells
errStem Cell Reports
IF5.1
err2026-07-16
err0
errOAAI
errRunxiang Qiu; Alejandra Velazquez Ojeda; Cesar Gonzalez; Vincente Abatay; Jun Wu; Dina Awabdeh; Renate Starr; Nadia Carlesso; Sarah Shuck; Yun Rose Li; Christine E. Brown; Michael E. Barish; Qiang Lu
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errSave
Whole-protein screening and multi-modal profiling of antigen-specific CD4+ T cells at single-cell resolution
errNature Communications
IF15.7
err2026-05-12
err0
errOAAI
errRongyu Zhang; Jingqi Qi; Michaela McKasson; Jongchan Choi; Vanessa Gutierrez; Conor Brennan; Sunga Hong; William Chour; Rachel H. Ng; Jingyi Xie; Dan Yuan; Andrew Webster; Simranjeet K. Sidhu; Abby Anderson; Daniel Chen; Rick Edmark; Kim M. Murray; Sarah Li; Connor McDonald; Lee Rowen; Shuo Wang; Yusuf Rasheed; Yapeng Su; Jamie R. Wagner; Jia Ming Chen; Karla Nawaly; Jie Fu; Alexandria Duven; Stephen J. Forman; Mihae Song; Saul J. Priceman; Christine E. Brown; Antoni Ribas; Deborah J. Wong; Kelly G. Paulson; Charles W. Drescher; Cristina Puig-Saus; Jason D. Goldman; Cornelia L. Trimble; James R. Heath
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errSave
Foundation Model Cascades Enable Zero-Shot Microscopy Image Analysis for Cell Therapy Manufacturing
errCytotherapy
IF3.2
err2026-02-03
err0
errOAAI
errRui Qi Chen; Yeonju Lee; Benjamin Joffe; Caroline E. Serafini; Paloma Casteleiro Costa; Bryan Wang; Bharat Kanwar; Stephen Balakirsky; Aaron D. Silva Trenkle; Linda E. Kippner; Isaac LeCompte; Ye Li; Christine E. Brown; Gabriel A. Kwong; Francisco E Robles; Krishnendu Roy; Jing Li
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errSave
Label-free in-line characterization of immune cell culture using quantitative phase imaging
errnpj Regenerative Medicine
IF6.5
err2025-11-27
err0
errOAAI
errCaroline E. Serafini; Viswanath Gorti; Paloma Casteleiro Costa; Aaron D. Silva Trenkle; Bharat Kanwar; Bryan Wang; Brian Wicker; Linda E. Kippner; Isaac LeCompte; Rui Qi Chen; Benjamin Joffe; Ye Li; Annie C. Bowles-Welch; Jing Li; Christine E. Brown; Gabriel A. Kwong; Stephen Balakirsky; Krishnendu Roy; Francisco E. Robles
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errSave
TMOD-27. Patient-derived glioblastoma organoid cultures for CAR T cell evaluation
errNeuro-Oncology
IF13.4
err2025-11-11
err0
errOAAI
errXiujian Ma; Eric Ma; Franklin Chen; Sean Sepulveda; Hernan Reza; Michael Rothe; Margarita Gutova; Behnam Badie; Christine Brown
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errSave
CTIM-07. A PHASE 1 STUDY OF INTRAVENTRICULARLY ADMINISTERED AUTOLOGOUS HER2-TARGETING CHIMERIC ANTIGEN RECEPTOR T CELLS (HER2-CAR T CELLS), WITH AND WITHOUT LYMPHODEPLETION, IN HER2-POSITIVE BREAST CANCER PATIENTS WITH RECURRENT BRAIN AND/OR LEPTOMENINGEAL METASTASES
errNeuro-Oncology
IF13.4
err2025-11-11
err0
errOAAI
errJana Portnow; Suzette Blanchard; Julie Kilpatrick; Lauren Adkins; Laura Luebbert; Gaurav Dhapola; Reginaldo Rosa; Behnam Badie; Tracey Stiller; Stephanie Shishido; Jamie Wagner; Monica Nisis; Christine Brown; Catalina Martinez; Lior Pachter; Peter Kuhn; Stephen Forman; Saul Priceman
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errSave
MR-MEASURED ADC AND FLUID FLOW AS PREDICTORS OF DECREASED PROGRESSION-FREE SURVIVAL IN PRIMARY BRAIN TUMOR PATIENTS RECEIVING IL12RA2 CAR-T THERAPY
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errWoodall, Ryan; Hibbard, Jonathan; Gutova, Margarita; Badie, Behnam; Brown, Christine; Rockne, Russell
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errSave
Development of EGFR/IL13Ra2 bispecific CAR T cells to overcome heterogeneous glioblastoma
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errDu, Kaixin; Villasenor, Yolanda; Machuca, Robert; Trac, Candi; Park, Miso; Ma, Eric; Masia, Christian; Rothe, Michael; Jewel, Yead; Williams, John; Brown, Christine
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errSave
PRELIMINARY PERFUSION IMAGING RESULTS FROM PHASE 1 STUDY OF IL13RΑ2-TARGETED CAR-T CELLS FOR LEPTOMENINGEAL BRAIN TUMORS
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errWoodall, Ryan; Blanchard, Suzette; Stiller, Tracey; Sepuleda, Sean; Gutova, Margarita; Wagner, Jamie; Nisis, Monica; Kilpatrick, Julie; Hibbard, Jonathan; Badie, Benham; Rockne, Russell; Brown, Christine; Feldman, Lisa
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errSave
Development of Clinically Relevant Patient-Derived Brain Tumor Models for Advancing Therapeutic Evaluation
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errGutova, Margarita; Ma, Eric; Natri, Heini; Sepulveda, Sean; Uyematsu, Spenser; Ma, Xuijian; Hibbard, Jonathan; Aftabizadeh, Maryam; Starr, Ranate; Aguilar, Brenda; D'apuzzo, Massimo; Banovich, Nicolas; Yuan, Yate-Chung; Badie, Behnam; Brown, Christine
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errSave
Accurate somatic small variant discovery for multiple sequencing technologies with DeepSomatic
errNature Biotechnology
IF41.7
err2025-10-16
err0
PREAI
errJimin Park; Daniel E. Cook; Pi-Chuan Chang; Alexey Kolesnikov; Lucas Brambrink; Juan Carlos Mier; Joshua Gardner; Brandy McNulty; Samuel Sacco; Ayse G. Keskus; Asher Bryant; Tanveer Ahmad; Jyoti Shetty; Yongmei Zhao; Bao Tran; Giuseppe Narzisi; Adrienne Helland; Byunggil Yoo; Irina Pushel; Lisa A. Lansdon; Chengpeng Bi; Adam Walter; Margaret Gibson; Tomi Pastinen; Rebecca Reiman; Sharvari Mankame; T. Rhyker Ranallo-Benavidez; Christine Brown; Nicolas Robine; Floris P. Barthel; Midhat S. Farooqi; Karen H. Miga; Andrew Carroll; Mikhail Kolmogorov; Benedict Paten; Kishwar Shafin
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errSave
CAR T-cell and oncolytic virus dynamics and determinants of combination therapy success for glioblastoma
errMATHEMATICAL BIOSCIENCES
IF1.8
err2025-09-01
err2
errOAAI
errConte, Martina; Xella, Agata; Woodall, Ryan T.; Cassady, Kevin A.; Branciamore, Sergio; Brown, Christine E.; Rockne, Russell C.
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errSave
Chlorotoxin-directed CAR T cell therapy for recurrent glioblastoma: Interim clinical experience demonstrating feasibility and safety
errCell Reports Medicine
IF10.6
err2025-08-15
err0
PREAI
errMichael E. Barish; Maryam Aftabizadeh; Jonathan Hibbard; M. Suzette Blanchard; Julie R. Ostberg; Jamie R. Wagner; Mishika Manchanda; Jinny Paul; Tracy Stiller; Brenda Aguilar; Renate Starr; Leonidas Arvanitis; Julie A. Ressler; Julie Kilpatrick; Yuthana Kong; Dongrui Wang; Stephen J. Forman; Massimo D’Apuzzo; Christine E. Brown; Behnam Badie
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errSave
Multimodal glioma immunotherapy combining TLR9-targeted STAT3 antisense oligodeoxynucleotides with PD1 immune checkpoint blockade
errNEURO-ONCOLOGY
IF13.4
err2025-06-01
err2
PREAI
errHung, Chia-Yang; Kang, Elaine Y.; Jacek, Karol; Yu, Chunsong; Zhang, Xiaowei; Zhu, Yicheng; Aftabizadeh, Maryam; Wong, Robyn A.; Badie, Benham; Swiderski, Piotr; Kaminska, Bozena; Alizadeh, Darya; Heimberger, Amy B.; Brown, Christine E.; Kortylewski, Marcin
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errSave
Targeting CEA in metastatic triple negative breast cancer with image-guided radiation followed by Fab-mediated chimeric antigen receptor (CAR) T-cell therapy
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-12-20
err0
errOAAI
errAniogo, Eric; Kujawski, Maciej; Awuah, Dennis; Cha, Seung E.; Espinosa, Ruby; Hui, Susanta; Ghimire, Hemendra; Yazaki, Paul J.; Brown, Christine E.; Wang, Xiuli; Shively, John E.
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errSave
CONQUERING SPP1+MYELOID-DRIVEN RESISTANCE OF GLIOBLASTOMA TO IL13RA2-TARGETED CAR T CELL THERAPY
errNEURO-ONCOLOGY
IF13.4
err2024-11-11
err0
PREAI
errGholamin, Sharareh; Natri, Heini M.; Zhao, Yuqi; Xu, Shengchao; Aftabizadeh, Maryam; Comin-Anduix, Begonya; Saravanakumar, Supraja; Masia, Christian; Wong, Robyn; Peter, Lance; Chung, Mei-i; Mee, Evan D.; Aguilar, Brenda; Starr, Renate; Torrejon, Davis Y.; Kalbasi, Anusha; Alizadeh, Darya; Wu, Xiwei; Ribas, Antoni; Forman, Stephen; Badie, Behnam; Banovich, Nicholas E.; Brown, Christine E.
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errSave
IL-13Rα2/TGF-β bispecific CAR-T cells counter TGF-β-mediated immune suppression and potentiate anti-tumor responses in glioblastoma
errNEURO-ONCOLOGY
IF13.4
err2024-10-03
err4
PREAI
errHou, Andrew J.; Shih, Ryan M.; Uy, Benjamin R.; Shafer, Amanda; Chang, ZeNan L.; Comin-Anduix, Begonya; Guemes, Miriam; Galic, Zoran; Phyu, Su; Okada, Hideho; Grausam, Katie B.; Breunig, Joshua J.; Brown, Christine E.; Nathanson, David A.; Prins, Robert M.; Chen, Yvonne Y.
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errSave
Evaluation of the Immunomodulatory Effects of Radiation for Chimeric Antigen Receptor T Cell Therapy in Glioblastoma Multiforme
errCELLS
IF5.2
err2024-06-21
err3
errOAAI
errAkhavan, David; Subham, Siddharth; Jeppson, John D.; Aguilar, Brenda; Wong, Robyn A.; Hibbard, Jonathan C.; Hui, Susanta; Wong, Jeffrey Y. C.; Forman, Stephen J.; Alizadeh, Darya; Brown, Christine E.
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errSave
Locoregional delivery of IL-13Rα2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial (JUNE, 10.1038/s41591-024-02875-1, 2023)
errNATURE MEDICINE
IF50
err2024-03-21
err0
errOAAI
errBrown, Christine E.; Hibbard, Jonathan C.; Alizadeh, Darya; Blanchard, M. Suzette; Natri, Heini M.; Wang, Dongrui; Ostberg, Julie R.; Aguilar, Brenda; Wagner, Jamie R.; Paul, Jinny A.; Starr, Renate; Wong, Robyn A.; Chen, Wuyang; Shulkin, Noah; Aftabizadeh, Maryam; Filippov, Aleksandr; Chaudhry, Ammar; Ressler, Julie A.; Kilpatrick, Julie; Myers-McNamara, Paige; Chen, Mike; Wang, Leo D.; Rockne, Russell C.; Georges, Joseph; Portnow, Jana; Barish, Michael E.; D'Apuzzo, Massimo; Banovich, Nicholas E.; Forman, Stephen J.; Badie, Behnam
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
A
Antoni Ribas
H-index: 158 · Papers: 1.7K
E
E. John Wherry
H-index: 142 · Papers: 638
T
Timothy F. Cloughesy
H-index: 128 · Papers: 1.4K
S
Stephen J. Forman
H-index: 127 · Papers: 1.8K
K
K. Christopher García
H-index: 119 · Papers: 544
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