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D

Daniel C. Douek

national institutes of health

137H-index
595Paper Count
7.5WCitation Count
Published Papers 284
Publication Date
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Potent type-specific de novo antibodies complement broadly reactive imprinted antibodies in immune responses to SARS-CoV-2 variants
errNature Immunology
IF27.6
err2026-08-14
err0
errOAAI
errTimothy S. Johnston; Shuk Hang Li; Mark M. Painter; Divya Swaminathan; Reilly K. Atkinson; Bernadeta Dadonaite; Shuishu Wang; Naomi R. Douek; Lucas Kampman; Robin Schlesinger; Rachel Kazmierski; Bob C. Lin; Leonid A. Serebryannyy; Haijuan Du; Amy R. Henry; Sarah C. Smith; Farida Laboune; I-Ting Teng; Lingshu Wang; Nicole A. Doria-Rose; Chaim A. Schramm; Theodore C. Pierson; Tongqing Zhou; Jesse D. Bloom; E. John Wherry; Scott E. Hensley; Daniel C. Douek
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IgA is necessary and sufficient to prevent norovirus infection in mice
errScience Translational Medicine
IF14.6
err2026-06-24
err0
PREAI
errArya B. Ökten; Renata B. Filler; Justin L. Kung; Zhenhao Fang; Brieyanna C. McWilliams; Jenna E. Muscat-Rivera; Michael S. Kegel; Ilze M. Olivi Gomes; Madeleine C. Mankowski; Ashwin N. Skelly; Jilian R. Melamed; Timothy J. Nice; Sanghyun Lee; Megan T. Baldridge; Thomas J. Smith; Christiane E. Wobus; Stephanie C. Eisenbarth; Adam Williams; Leonid A. Serebryannyy; Daniel C. Douek; Drew Weissman; Sidi Chen; Edward F. Kreider; Joseph E. Craft; Craig B. Wilen
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Neutralizing antibodies elicited in nonhuman primates by an enterovirus D68 virus-like particle vaccine target receptor binding sites
errScience Translational Medicine
IF14.6
err2026-06-03
err0
PREAI
errDaniel L. Moss; Jiaxuan Cheng; Peter W. Krug; Alden C. Paine; Brian E. Fisher; Amy R. Henry; Jesmine Roberts-Torres; Timothy S. Johnston; Sarah C. Smith; Sergei Pletnev; Haotian Lei; Nicholas C. Morano; Theodore C. Pierson; Lawrence Shapiro; Tongqing Zhou; Peter D. Kwong; Daniel C. Douek; Masaru Kanekiyo; Tracy J. Ruckwardt
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SARS-CoV-2 vaccination and infection elicit cross-neutralizing responses against clade 3 and 4 sarbecoviruses
errNature Communications
IF15.7
err2026-04-16
err0
errOAAI
errStephen D. Schmidt; Rahul Subramanian; Manjula Basappa; Robin Carroll; Megi Rexhepaj; Christine M. Posavad; Jeffrey A. Liao; Jennifer A. Bohl; Ananda Chowdhury; Alicen B. Spaulding; Bob C. Lin; Mike Castro; Richard A. Koup; Leonid A. Serebryannyy; Daniel C. Douek
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Novel Lineages of SARS-CoV-2 Receptor Binding Domain Monoclonal Antibodies Demonstrate Broad and Potent Neutralization Across SARS-CoV-2 and Other Sarbecoviruses
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errMcKim, Quenelle; Wang, Lingshu; Zhou, Tongqing; Musayev, Maryam; Smith, Sarah K.; Schramm, Chaim A.; Henry, Amy R.; Bush, Sabrina; Teng, I-Ting; O'dell, Sijy; Tourtellott-Fogt, Emily; Qiu, Qi; Zhou, Qiong; Shimberg, Geoffrey; Nguyen, Richard; Ambrozak, David; Dropulic, Lesia; Novik, Laura; Kwong, Peter D.; Misasi, John; Koup, Richard A.; Douek, Daniel C.; Pierson, Theodore C.; Doria-Rose, Nicole A.
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Characterization of MPER broad neutralizing antibodies in a person living with HIV-1
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errJacob, Sari; Arora, Juhi; Birungi, Kevina; Nortelus, Sarah; Law, William; Zhou, Kenneth; Schramm, Chaim A.; Kwon, Young Do; Henry, Amy; Smith, Sarah; Roberts-Torres, Jesmine; Ambrozak, David; Nguyen, Richard; Rolland, Morgane; Townsley, Samantha; Pierson, Theodore; Cale, Evan; Robb, Merlin; Douek, Daniel; Krebs, Shelly; Doria-Rose, Nicole
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Cross-neutralizing and potent human monoclonal antibodies against historical and emerging H5Nx influenza viruses
errNature Microbiology
IF19.4
err2025-10-14
err0
errOAAI
errAlexandra A. Abu-Shmais; Gray Freeman; Adrian Creanga; Matthew J. Vukovich; Tek Malla; Grace E. Mantus; Geoffrey D. Shimberg; Rebecca A. Gillespie; Vanessa Guerra Canedo; Bernadeta Dadonaite; Megan D. Rodgers; Ankita J. Chopde; Elizabeth Bardwil-Lugones; Tatsiana Bylund; Amy R. Henry; Jesmine Roberts-Torres; Timothy S. Johnston; Sarah Smith; Eun Sung Yang; Cheng Cheng; Emma L. Walker; Michelle Ravichandran; Ingelise J. Gordon; Tejaswi S. Dittakavi; Douglas S. Reed; Theodore C. Pierson; Lesia Dropulic; Jesse D. Bloom; Yaroslav Tsybovsky; Eli A. Boritz; Daniel C. Douek; Tongqing Zhou; Masaru Kanekiyo; Sarah F. Andrews
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Chronic sublethal exposure to methylmercury lengthens telomeres in developing zebra finches
errEnvironmental Pollution
IF7.3
err2025-09-21
err0
PREAI
errRachel L. Davis; Samuel D. Mason; Christian Wake; Giulia Fabozzi; William L. Catalano; Chaim A. Schramm; Amy R. Henry; Cokie L. Parker; Farida Laboune; Casey L. McLaughlin; Jeffrey D. Kittilson; John P. Swaddle; Daniel A. Cristol; Britt J. Heidinger; Daniel C. Douek
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Functional; immunogenetic; and structural convergence in influenza immunity between humans and macaques
errScience Translational Medicine
IF14.6
err2025-09-10
err0
errOAAI
errMaya Sangesland; Ning Li; Yaroslav Tsybovsky; Megan D. Rodgers; Julianna Han; Alesandra J. Rodriguez; James A. Ferguson; Amy R. Henry; Sarah C. Smith; Jesmine Roberts-Torres; Rebecca A. Gillespie; Cuiping Liu; Jonah S. Merriam; Tyler Stephens; Connor Williams; Emma Walker; Martin Corcoran; Michelle Ravichandran; Adrian Creanga; Sarah F. Andrews; Theodore C. Pierson; Gunilla B. Karlsson Hedestam; Chaim A. Schramm; Douglas S. Reed; Daniel C. Douek; Tongqing Zhou; Andrew B. Ward; Masaru Kanekiyo
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HKU5 bat merbecoviruses engage bat and mink ACE2 as entry receptors
errNature Communications
IF15.7
err2025-07-24
err0
errOAAI
errMia Madel Alfajaro; Emma L. Keeler; Ning Li; Nicholas J. Catanzaro; I-Ting Teng; Zhe Zhao; Michael W. Grunst; Boyd Yount; Alexandra Schäfer; Danyi Wang; Arthur S. Kim; Aleksandra Synowiec; Mario A. Peña-Hernández; Samantha Zepeda; Ridwan Arinola; Ramandeep Kaur; Bridget L. Menasche; Jin Wei; Gabriel A. Russell; John Huck; Jaewon Song; Aaron Ring; Akiko Iwasaki; Rohit K. Jangra; Sanghyun Lee; David R. Martinez; Walther Mothes; Pradeep D. Uchil; John G. Doench; Alicen B. Spaulding; Ralph S. Baric; Leonid Serebryannyy; Yaroslav Tsybovsky; Tongqing Zhou; Daniel C. Douek; Craig B. Wilen
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Immunological duet between CD4+ T cells and B cells in the lung following an intranasal protein boost v
errNATURE IMMUNOLOGY
IF27.6
err2025-05-23
err0
PREAI
errGagne, Matthew; Douek, Daniel C.; Seder, Robert A.
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A broadly protective human antibody for GI genogroup noroviruses
errNATURE MICROBIOLOGY
IF19.4
err2025-04-10
err0
PREAI
errRimkute, Inga; Olia, Adam S.; Suleiman, Mehin; Woods, Kamron D.; Bylund, Tatsiana; Morano, Nicholas C.; Tully, Ena S.; Verardi, Raffaello; Bao, Saran; Beddall, Margaret H.; Chaimongkol, Natthawan; Donaldson, Mitzi M.; Du, Renguang; Dulan, Caitlyn N. M.; Gorman, Jason; Henry, Amy R.; Schramm, Chaim A.; Sosnovtsev, Stanislav V.; Stephens, Tyler; Todd, John-Paul; Tsybovsky, Yaroslav; Douek, Daniel C.; Green, Kim Y.; Rawi, Reda; Shapiro, Lawrence; Zhou, Tongqing; Roederer, Mario
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Passive infusion of an S2-Stem broadly neutralizing antibody protects against SARS-CoV-2 infection and lower airway inflammation in rhesus macaques
errPLOS PATHOGENS
IF4.9
err2025-01-23
err0
errOAAI
errEdwards, Christopher T.; Karunakaran, Kirti A.; Garcia, Elijah; Beutler, Nathan; Gagne, Matthew; Golden, Nadia; Aoued, Hadj; Pellegrini, Kathryn L.; Burnett, Matthew R.; Honeycutt, Christopher Cole; Lapp, Stacey A.; Ton, Thang; Lin, Mark C.; Metz, Amanda; Bombin, Andrei; Goff, Kelly; Scheuermann, Sarah E.; Wilkes, Amelia; Wood, Jennifer S.; Ehnert, Stephanie; Weissman, Stacey; Curran, Elizabeth H.; Roy, Melissa; Dessasau, Evan; Paiardini, Mirko; Upadhyay, Amit A.; Moore, Ian N.; Maness, Nicholas J.; Douek, Daniel C.; Piantadosi, Anne; Andrabi, Raiees; Rogers, Thomas R.; Burton, Dennis R.; Bosinger, Steven E.
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Cytokines dynamics and biological sex differences in SARS-CoV-2 infected people in Cameroon
errCLINICAL AND EXPERIMENTAL IMMUNOLOGY
IF3.8
err2025-01-01
err0
PREAI
errTene, Hillary; Ngamaleu, Romuald; Djounda, Romeo; Minomo, Rachel; Ngale, Sabine; Besong, Micheal; Awanakam, Honore; Nganou-Makamdop, Krystelle; Essomba, Rene; Bigoga, Jude; Douek, Daniel C.; Esemu Livo, Forgu
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Chronic inflammation degrades CD4 T cell immunity to prior vaccines in treated HIV infection
errNATURE COMMUNICATIONS
IF15.7
err2024-11-25
err0
errOAAI
errKiessling, Melissa; Cole, John J.; Kuebel, Sabrina; Klein, Paulina; Korn, Klaus; Henry, Amy R.; Laboune, Farida; Fourati, Slim; Harrer, Ellen; Harrer, Thomas; Douek, Daniel C.; Ueberla, Klaus; Nganou-Makamdop, Krystelle
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A multispecific antibody against SARS-CoV-2 prevents immune escape in vitro and confers prophylactic protection in vivo
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2024-10-09
err0
PREAI
errMisasi, John; Wei, Ronnie R.; Wang, Lingshu; Pegu, Amarendra; Wei, Chih-Jen; Oloniniyi, Olamide K.; Zhou, Tongqing; Moliva, Juan I.; Zhao, Bingchun; Choe, Misook; Yang, Eun Sung; Zhang, Yi; Boruszczak, Marika; Chen, Man; Leung, Kwanyee; Li, Juan; Yang, Zhi-Yong; Andersen, Hanne; Carlton, Kevin; Godbole, Sucheta; Harris, Darcy R.; Henry, Amy R.; Ivleva, Vera B.; Lei, Q. Paula; Liu, Cuiping; Longobardi, Lindsay; Merriam, Jonah S.; Nase, Danielle; Olia, Adam S.; Pessaint, Laurent; Porto, Maciel; Shi, Wei; Wallace, Shannon M.; Wolff, Jeremy J.; Douek, Daniel C.; Suthar, Mehul S.; Gall, Jason G.; Koup, Richard A.; Kwong, Peter D.; Mascola, John R.; Nabel, Gary J.; Sullivan, Nancy J.
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Mucosal adenovirus vaccine boosting elicits IgA and durably prevents XBB.1.16 infection in nonhuman primates
errNATURE IMMUNOLOGY
IF27.6
err2024-09-03
err2
errOAAI
errGagne, Matthew; Flynn, Barbara J.; Andrew, Shayne F.; Marquez, Josue; Flebbe, Dillon R.; Mychalowych, Anna; Lamb, Evan; Davis-Gardner, Meredith E.; Burnett, Matthew R.; Serebryannyy, Leonid A.; Lin, Bob C.; Ziff, Zohar E.; Maule, Erin; Carroll, Robin; Naisan, Mursal; Jethmalani, Yogita; Pessaint, Laurent; Todd, John-Paul M.; Doria-Rose, Nicole A.; Case, James Brett; Dmitriev, Igor P.; Kashentseva, Elena A.; Ying, Baoling; Dodson, Alan; Kouneski, Katelyn; O'Dell, Sijy; Wali, Bushra; Ellis, Madison; Godbole, Sucheta; Laboune, Farida; Henry, Amy R.; Teng, I-Ting; Wang, Danyi; Wang, Lingshu; Zhou, Qiong; Zouantchangadou, Serge; Van Ry, Alex; Lewis, Mark G.; Andersen, Hanne; Kwong, Peter D.; Curiel, David T.; Roederer, Mario; Nason, Martha C.; Foulds, Kathryn E.; Suthar, Mehul S.; Diamond, Michael S.; Douek, Daniel C.; Seder, Robert A.
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Administration of anti-HIV-1 broadly neutralizing monoclonal antibodies with increased affinity to Fcγ receptors during acute SHIVAD8-EO infection
errNATURE COMMUNICATIONS
IF15.7
err2024-08-29
err2
errOAAI
errDias, Joana; Fabozzi, Giulia; Fourati, Slim; Chen, Xuejun; Liu, Cuiping; Ambrozak, David R.; Ransier, Amy; Laboune, Farida; Hu, Jianfei; Shi, Wei; March, Kylie; Maximova, Anna A.; Schmidt, Stephen D.; Samsel, Jakob; Talana, Chloe A.; Ernste, Keenan; Ko, Sung Hee; Lucas, Margaret E.; Radecki, Pierce E.; Boswell, Kristin L.; Nishimura, Yoshiaki; Todd, John-Paul; Martin, Malcolm A.; Petrovas, Constantinos; Boritz, Eli A.; Doria-Rose, Nicole A.; Douek, Daniel C.; Sekaly, Rafick-Pierre; Lifson, Jeffrey D.; Asokan, Mangaiarkarasi; Gama, Lucio; Mascola, John R.; Pegu, Amarendra; Koup, Richard A.
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Clonal succession after prolonged antiretroviral therapy rejuvenates CD8+ T cell responses against HIV-1
errNATURE IMMUNOLOGY
IF27.6
err2024-08-23
err1
PREAI
errWhite, Eoghann; Papagno, Laura; Samri, Assia; Sugata, Kenji; Hejblum, Boris; Henry, Amy R.; Rogan, Daniel C.; Darko, Samuel; Recordon-Pinson, Patricia; Dudoit, Yasmine; Llewellyn-Lacey, Sian; Chakrabarti, Lisa A.; Buseyne, Florence; Migueles, Stephen A.; Price, David A.; Andreola, Marie-Aline; Satou, Yorifumi; Thiebaut, Rodolphe; Katlama, Christine; Autran, Brigitte; Douek, Daniel C.; Appay, Victor
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Variant-proof high affinity ACE2 antagonist limits SARS-CoV-2 replication in upper and lower airways
errNATURE COMMUNICATIONS
IF15.7
err2024-08-12
err0
errOAAI
errGagne, Matthew; Flynn, Barbara J.; Honeycutt, Christopher Cole; Flebbe, Dillon R.; Andrew, Shayne F.; Provost, Samantha J.; Mccormick, Lauren; Van Ry, Alex; Mccarthy, Elizabeth; Todd, John-Paul M.; Bao, Saran; Teng, I-Ting; Marciano, Shir; Rudich, Yinon; Li, Chunlin; Jain, Shilpi; Wali, Bushra; Pessaint, Laurent; Dodson, Alan; Cook, Anthony; Lewis, Mark G.; Andersen, Hanne; Zahradnik, Jiri; Suthar, Mehul S.; Nason, Martha C.; Foulds, Kathryn E.; Kwong, Peter D.; Roederer, Mario; Schreiber, Gideon; Seder, Robert A.; Douek, Daniel C.
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Research Directions

No research directions
Co-authors
Cooperation Journals
A
Anthony S. Fauci
H-index: 185 · Papers: 1.1K
C
Carl H. June
H-index: 177 · Papers: 1.4K
B
Bruce D. Walker
H-index: 160 · Papers: 945
R
Russell P. Tracy
H-index: 157 · Papers: 1.2K
S
Steven M. Holland
H-index: 155 · Papers: 1.9K
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