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J

JoAnne L. Flynn

university of pittsburgh

96H-index
337Paper Count
3.4WCitation Count
Published Papers 115
Publication Date
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The immunometabolic topography of cellular organization and bacterial control in tuberculosis granulomas
errNature Immunology
IF27.6
err2026-02-23
err0
PREAI
errErin F. McCaffrey; Alea C. Delmastro; Isobel Fitzhugh; Jolene S. Ranek; Sarah Douglas; Joshua M. Peters; Christine Camacho Fullaway; Marc Bosse; Candace C. Liu; Craig Gillen; Noah F. Greenwald; Sarah Anzick; Craig Martens; Seth Winfree; Yunhao Bai; Cameron Sowers; Mako Goldston; Alex Kong; Potchara Boonrat; Carolyn L. Bigbee; Roopa Venugopalan; Pauline Maiello; Edwin Klein; Mark A. Rodgers; Charles A. Scanga; Philana Ling Lin; Sean C. Bendall; Denise E. Kirschner; Sarah M. Fortune; Bryan D. Bryson; J. Russell Butler; Joshua T. Mattila; JoAnne L. Flynn; Michael Angelo
errShare
errSave
Protection against reinfection with Mycobacterium tuberculosis extends across heterologous Mtb lineages
errMucosal Immunology
IF7.6
err2025-11-02
err0
errOAAI
errAndrew W Simonson; Michael C Chao; Luke E Hood; Rachel A Donlan; Forrest Hopkins; Michael R Chase; Andrew J Vickers; Alanna Callendrello; Edwin Klein; HJacob Borish; Marshall Malin; Pauline Maiello; Charles A Scanga; Philana Ling Lin; Sarah M Fortune; JoAnne L Flynn
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errSave
Single-cell profiling reveals a role for tuberculosis-induced myofibroblasts in the immunopathology of infected lungs
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errLiu, Nuo; Mbano, Ian Maheti; Wardsworth, Marc; Chambers, Mark; Mpotje, Thabo; Asowata, Osaretin; Nyquist, Sarah; Nargan, Kievershen; Ramsuran, Duran; Karim, Farina; Hughes, Travis; Bromley, Joshua; Krause, Robert; Tezera, Liku; Reichmann, Michaela; Keanne, Sharie; Ganchua, C.; Kloverpris, Henrik; Dullabh, Kaylesh; Madansein, Rajhmun; Triana, Sergio; Steyn, Adrie; Berger, Bonnie; Marakalala, Mohlopheni; Fortune, Sarah; Flynn, Joanne L.; Elkington, Paul T.; Shalek, Alex K.; Leslie, Alasdair
errShare
errSave
Synergistic CD8+T and CD4+T cell concomitant immunity controls M. tuberculosis bacterial burden following M. tuberculosis reinfection in non-human primates
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errShan, Feng; Simonson, Andrew W.; Bromley, Joshua D.; Chao, Michael; Megahed, Doaa; Flynn, JoAnne L.; Fortune, Sarah M.; Shalek, Alex K.
errShare
errSave
Protecting simian immunodeficiency virus-infected macaques from Mycobacterium tuberculosis by intravenous Bacillus Calmette-Guérin vaccination requires viral control
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errJauro, Solomon; Larson, Erica C.; Wahlberg, Brendon; Rodgers, Mark A.; Gleim, Janelle L.; Hood, Luke E.; Collins, Mallory K.; Tomko, Jaime A.; Jacob Borish, Henry; Maiello, Pauline; Demarco, Todd; Potter, Lake; Darrah, Patricia A.; Seder, Robert; Roederer, Mario; Lin, Philana Ling; Flynn, Joanne L.; Scanga, Charles A.
errShare
errSave
Effective protection against secondary Mycobacterium tuberculosis challenge with heterologous strain
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errSimonson, Andrew W.; Chao, Michael; Hopkins, Forrest; Chase, Michael R.; Vickers, Andrew J.; Hood, Luke E.; Donlan, Rachel; Malin, Marshall; Jacob Borish, Henry; Maiello, Pauline; Lin, Philana Ling; Fortune, Sarah M.; Flynn, Joanne L.
errShare
errSave
Host-intrinsic and host-extrinsic factors modulate immunity to Mtb infection, reinfection, and noncanonical vaccination routes
errCell Reports Medicine
IF10.6
err2025-08-07
err0
errOAAI
errJoshua D. Bromley; Andrew W. Simonson; Alex K. Shalek; JoAnne L. Flynn
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errSave
Intravenous BCG-mediated protection against tuberculosis requires CD4+ T cells and CD8α+ lymphocytes
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2025-02-06
err2
errOAAI
errSimonson, Andrew W.; Zeppa, Joseph J.; Bucsan, Allison N.; Chao, Michael C.; Pokkali, Supriya; Hopkins, Forrest; Chase, Michael R.; Vickers, Andrew J.; Sutton, Matthew S.; Winchell, Caylin G.; Myers, Amy J.; Ameel, Cassaundra L.; Kelly, Ryan J.; Krouse, Ben; Hood, Luke E.; Li, Jiaxiang; Lehman, Chelsea C.; Kamath, Megha; Tomko, Jaime; Rodgers, Mark A.; Donlan, Rachel; Chishti, Harris; Borish, H. Jacob; Klein, Edwin; Scanga, Charles A.; Fortune, Sarah M.; Lin, Philana Ling; Maiello, Pauline; Roederer, Mario; Darrah, Patricia A.; Seder, Robert A.; Flynn, JoAnne L.
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errSave
CD4+T cells re-wire granuloma cellularity and regulatory networks to promote immunomodulation following Mtb reinfection
errIMMUNITY
IF26.3
err2024-10-01
err0
errOAAI
errBromley, Joshua D.; Ganchua, Sharie Keanne C.; Nyquist, Sarah K.; Maiello, Pauline; Chao, Michael; Borish, H. Jacob; Rodgers, Mark; Tomko, Jaime; Kracinovsky, Kara; Mugahid, Douaa; Nguyen, Son; Wang, Qianchang Dennis; Rosenberg, Jacob M.; Klein, Edwin C.; Gideon, Hannah P.; Floyd-O'Sullivan, Roisin; Berger, Bonnie; Scanga, Charles A.; Lin, Philana Ling; Fortune, Sarah M.; Shalek, Alex K.; Flynn, JoAnne L.
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errSave
Intravenous Bacillus Calmette-Guerin (BCG) Induces a More Potent Airway and Lung Immune Response than Intradermal BCG in Simian Immunodeficiency Virus-infected Macaques
errJOURNAL OF IMMUNOLOGY
IF3.4
err2024-09-23
err1
PREAI
errJauro, Solomon; Larson, Erica C.; Gleim, Janelle L.; Wahlberg, Brendon M.; Rodgers, Mark A.; Chehab, Julia C.; Lopez-Velazques, Alondra E.; Ameel, Cassaundra L.; Tomko, Jaime A.; Sakal, Jennifer L.; Demarco, Todd; Borish, H. Jacob; Maiello, Pauline; Potter, E. Lake; Roederer, Mario; Lin, Philana Ling; Flynn, JoAnne L.; Scanga, Charles A.
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errSave
Defining a core breath profile for healthy, non-human primates
errSCIENTIFIC REPORTS
IF3.9
err2024-07-23
err0
errOAAI
errBobak, Carly A.; Stevenson, Keisean A. J. M.; Sun, Ning; Khan, Mohammad S.; Azmir, Jannatul; Beccaria, Marco; Tomko, Jaime A.; Fillmore, Daniel; Scanga, Charles A.; Lin, Philana L.; Flynn, JoAnne L.; Hill, Jane E.
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errSave
Distributable, metabolic PET reporting of tuberculosis
errNATURE COMMUNICATIONS
IF15.7
err2024-06-27
err0
errOAAI
errKhan, R. M. Naseer; Ahn, Yong-Mo; Marriner, Gwendolyn A.; Via, Laura E.; D'Hooge, Francois; Lee, Seung Seo; Yang, Nan; Basuli, Falguni; White, Alexander G.; Tomko, Jaime A.; Frye, L. James; Scanga, Charles A.; Weiner, Danielle M.; Sutphen, Michelle L.; Schimel, Daniel M.; Dayao, Emmanuel; Piazza, Michaela K.; Gomez, Felipe; Dieckmann, William; Herscovitch, Peter; Mason, N. Scott; Swenson, Rolf; Kiesewetter, Dale O.; Backus, Keriann M.; Geng, Yiqun; Raj, Ritu; Anthony, Daniel C.; Flynn, JoAnne L.; Barry III, Clifton E.; Davis, Benjamin G.
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errSave
A measles-vectored vaccine candidate expressing prefusion-stabilized SARS-CoV-2 spike protein brought to phase I/II clinical trials: protection of African green monkeys from COVID-19 disease
errJOURNAL OF VIROLOGY
IF3.8
err2024-05-14
err3
PREAI
errNambulli, Sham; Escriou, Nicolas; Rennick, Linda J.; Demers, Matthew J.; Tilston-Lunel, Natasha L.; McElroy, Anita K.; Barbeau, Dominique J.; Crossland, Nicholas A.; Hoehl, Ryan M.; Schrauf, Sabrina; White, Alexander G.; Borish, H. Jacob; Tomko, Jaime A.; Frye, Lonnie J.; Scanga, Charles A.; Flynn, JoAnne L.; Martin, Annette; Gerke, Christiane; Hartman, Amy L.; Duprex, W. Paul
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errSave
CD8+ lymphocytes are critical for early control of tuberculosis in macaques
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2023-10-16
err13
errOAAI
errWinchell, Caylin G.; Nyquist, Sarah K.; Chao, Michael C.; Maiello, Pauline; Myers, Amy J.; Hopkins, Forrest; Chase, Michael; Gideon, Hannah P.; Patel, Kush V.; Bromley, Joshua D.; Simonson, Andrew W.; Floyd-O'Sullivan, Roisin; Wadsworth, Marc; Rosenberg, Jacob M.; Uddin, Rockib; Hughes, Travis; Kelly, Ryan J.; Griffo, Josephine; Tomko, Jaime; Klein, Edwin; Berger, Bonnie; Scanga, Charles A.; Mattila, Joshua; Fortune, Sarah M.; Shalek, Alex K.; Lin, Philana Ling; Flynn, JoAnne L.
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errSave
Blood transcriptional correlates of BCG-induced protection against tuberculosis in rhesus macaques
errCELL REPORTS MEDICINE
IF10.6
err2023-07-01
err9
errOAAI
errLiu, Yiran E.; Darrah, Patricia A.; Zeppa, Joseph J.; Kamath, Megha; Laboune, Farida; Douek, Daniel C.; Maiello, Pauline; Roederer, Mario; Flynn, JoAnne L.; Seder, Robert A.; Khatri, Purvesh
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errSave
Mycobacterium tuberculosis-Specific CD4 T Cells Expressing Transcription Factors T-Bet or ROR?T Associate with Bacterial Control in Granulomas
errMBIO
IF4.7
err2023-06-27
err6
errOAAI
errGrant, Nicole L.; Kelly, Kristen; Maiello, Pauline; Abbott, Helena; O'Connor, Shelby; Lin, Philana Ling; Scanga, Charles A.; Flynn, JoAnne L.
errShare
errSave
Optimizing Tuberculosis Treatment Efficacy: comparing the Standard Regimen with Moxifloxacin-containing Regimens
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2023-06-01
err0
errOAAI
errBudak, Maral; Linderman, Jennifer; Flynn, JoAnne; Kirschner, Denise
errShare
errSave
Macrophages and neutrophils in lymph node granulomas from Mycobacterium tuberculosis-infected macaques have immunoregulatory phenotypes
errJOURNAL OF IMMUNOLOGY
IF3.4
err2023-05-01
err0
errOAAI
errMattila, Joshua T.; Simonson, Andrew W.; Krupinsky, Kathryn C.; Kirschner, Denise E.; Flynn, JoAnne L.
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errSave
Characterizing the Spectrum of Latent Mycobacterium tuberculosis in the Cynomolgus Macaque Model: Clinical, Immunologic, and Imaging Features of Evolution
errJOURNAL OF INFECTIOUS DISEASES
IF4.5
err2023-01-06
err6
errOAAI
errMedrano, Jessica Marie; Maiello, Pauline; Rutledge, Tara; Tomko, Jaime; Rodgers, Mark A.; Fillmore, Daniel; Frye, L. James; Janssen, Christopher; Klein, Edwin; Flynn, JoAnne L.; Lin, Philana Ling
errShare
errSave
Concomitant immunity to M. tuberculosis infection
errSCIENTIFIC REPORTS
IF3.9
err2022-12-01
err7
errOAAI
errJoslyn, Louis R.; Flynn, JoAnne L.; Kirschner, Denise E.; Linderman, Jennifer J.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
A
Alessandro Sette
H-index: 174 · Papers: 1.4K
A
Arturo Casadevall
H-index: 144 · Papers: 1.5K
D
Daniel C. Douek
H-index: 137 · Papers: 595
A
Alan Sher
H-index: 133 · Papers: 555
M
Mario Roederer
H-index: 129 · Papers: 590
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