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Integrase anchors viral RNA to the HIV-1 capsid interior Singer, Matthew R.; Li, Zhen; Rey, Juan S.; Hope, Joshua; Chenavier, Florian; Cook, Nicola J.; Punch, Emma; Smith, Jamie; Zhou, Zhiyu; Maslen, Sarah; Masino, Laura; Nans, Andrea; Skehel, Mark; Taylor, Ian A.; Zanetti, Giulia; Zhang, Peijun; Perilla, Juan R.; Engelman, Alan N.; Cherepanov, Peter Share Save
Development and validation of HIV SMRTcap for the characterization of HIV-1 reservoirs across tissues and subtypes Sadri, Ghazal; Nadakal, Steven T.; Lauer, William; Kos, Justin; Singh, Parmit K.; Elliott, Erin; Kaiser, Catherine W.; Ford, Easton E.; Richardson, Nadia; Shields, Kaitlyn M.; Hudson, Elizabeth; Linden, Noemi L.; Danesh, Ali; Powell, James; Warburton, Peter; Soto, Juan; Emery, Matthew; Deikus, Gintaras; Lee, Guinevere Q.; Lamers, Susanna L.; Reynolds, Steven J.; Galiwango, Ronald; Prodger, Jessica L.; Tomusange, Stephen; Kityamuweesi, Taddeo; Han, Tina; Jones, R. Brad; Tobian, Aaron A. R.; Engelman, Alan N.; Sebra, Robert; Morgello, Susan; Redd, Andrew D.; Sachs, David; Rouchka, Eric; Smith, Melissa L. Share Save
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Structural and mechanistic bases for resistance of the M66I capsid variant to lenacapavir Briganti, Lorenzo; Annamalai, Arun S.; Bester, Stephanie M.; Wei, Guochao; Andino-Moncada, Jonathan R.; Singh, Satya P.; Kleinpeter, Alex B.; Tripathi, Meghna; Nguyen, Binh; Radhakrishnan, Rajalingam; Singh, Parmit K.; Greenwood, Juliet; Schope, Lauren I.; Haney, Reed; Huang, Szu-Wei; Freed, Eric O.; Engelman, Alan N.; Francis, Ashwanth C.; Kvaratskhelia, Mamuka Share Save
CPSF6 promotes HIV-1 preintegration complex function Chaudhuri, Evan; Jang, Sooin; Chakraborty, Rajasree; Radhakrishnan, Rajalingam; Arnarson, Bjarki; Prakash, Prem; Cornish, Daphne; Rohlfes, Nicholas; Singh, Parmit K.; Shi, Jiong; Aiken, Christopher; Campbell, Edward; Hultquist, Judd; Balsubramaniam, Muthukumar; Engelman, Alan N.; Dash, Chandravanu Share Save
Spatiotemporal binding of cyclophilin A and CPSF6 to capsid regulates HIV-1 nuclear entry and integration Ingram, Zachary; Kline, Christopher; Hughson, Alexandra K.; Singh, Parmit K.; Fischer, Hannah L.; Radhakrishnan, Rajalingham; Sowd, Gregory A.; Dos Santos, Nayara F. B.; Ganser-Pornillos, Barbie K.; Watkins, Simon C.; Kane, Melissa; Engelman, Alan N.; Ambrose, Zandrea Share Save
The primary mechanism for highly potent inhibition of HIV-1 maturation by lenacapavir Huang, Szu-Wei; Briganti, Lorenzo; Annamalai, Arun S.; Greenwood, Juliet; Shkriabai, Nikoloz; Haney, Reed; Armstrong, Michael L.; Wempe, Michael F.; Singh, Satya Prakash; Francis, Ashwanth C.; Engelman, Alan N.; Kvaratskhelia, Mamuka Share Save
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HIV-1 usurps mixed-charge domain-dependent CPSF6 phase separation for higher-order capsid binding, nuclear entry and viral DNA integration Jang, Sooin; Bedwell, Gregory J.; Singh, Satya P.; Yu, Hyun Jae; Arnarson, Bjarki; Singh, Parmit K.; Radhakrishnan, Rajalingam; Douglas, AidanDarian W.; Ingram, Zachary M.; Freniere, Christian; Akkermans, Onno; Sarafianos, Stefan G.; Ambrose, Zandrea; Xiong, Yong; Anekal, Praju, V; Montero Llopis, Paula; Kewalramani, Vineet N.; Francis, Ashwanth C.; Engelman, Alan N. Share Save
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Viral and host mediators of non-suppressible HIV-1 viremia Mohammadi, Abbas; Etemad, Behzad; Zhang, Xin; Li, Yijia; Bedwell, Gregory J.; Sharaf, Radwa; Kittilson, Autumn; Melberg, Meghan; Crain, Charles R.; Traunbauer, Anna K.; Wong, Colline; Fajnzylber, Jesse; Worrall, Daniel P.; Rosenthal, Alex; Jordan, Hannah; Jilg, Nikolaus; Kaseke, Clarety; Giguel, Francoise; Lian, Xiaodong; Deo, Rinki; Gillespie, Elisabeth; Chishti, Rida; Abrha, Sara; Adams, Taylor; Siagian, Abigail; Dorazio, Dominic; Anderson, Peter L.; Deeks, Steven G.; Lederman, Michael M.; Yawetz, Sigal; Kuritzkes, Daniel R.; Lichterfeld, Mathias D.; Sieg, Scott; Tsibris, Athe; Carrington, Mary; Brumme, Zabrina L.; Castillo-Mancilla, Jose R.; Engelman, Alan N.; Gaiha, Gaurav D.; Li, Jonathan Z. Share Save
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The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores Shen, Qi; Kumari, Sushila; Xu, Chaoyi; Jang, Sooin; Shi, Jiong; Burdick, Ryan C.; Levintov, Lev; Xiong, Qiancheng; Wu, Chunxiang; Devarkar, Swapnil C.; Tian, Taoran; Tripler, Therese N.; Hu, Yingxia; Yuan, Shuai; Temple, Joshua; Feng, Qingzhou; Lusk, Patrick; Aiken, Christopher; Engelman, Alan N.; Perilla, Juan R.; Pathak, Vinay K.; Lin, Chenxian; Xiong, Yong Share Save
The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function Singer, Matthew R.; Dinh, Tung; Levintov, Lev; Annamalai, Arun S.; Rey, Juan S.; Briganti, Lorenzo; Cook, Nicola J.; Pye, Valerie E.; Taylor, Ian A.; Kim, Kyungjin; Engelman, Alan N.; Kim, Baek; Perilla, Juan R.; Kvaratskhelia, Mamuka; Cherepanova, Peter Share Save
Modeling HIV-1 nuclear entry with nucleoporin-gated DNA-origami channels Shen, Qi; Feng, Qingzhou; Wu, Chunxiang; Xiong, Qiancheng; Tian, Taoran; Yuan, Shuai; Shi, Jiong; Bedwell, Gregory J.; Yang, Ran; Aiken, Christopher; Engelman, Alan N.; Lusk, C. Patrick; Lin, Chenxiang; Xiong, Yong Share Save
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