Nicholas J. Savill - Publications, H-index & Citations

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Nicholas J. Savill

university of edinburgh

34H-index

92Paper Count

3.5KCitation Count

Published Papers 33

Publication Date

Stunning Intricacies of RNA Editing Complexes RECC, RESC, and REH2C: Functional Organization, Developmental Regulation, and Evolutionary History in Kinetoplastid Protists

WIREs RNA

IF0

2026-02-25

OAAI

Suzanne M. McDermott; Julius Lukeš; Laurie K. Read; Reza Salavati; Achim Schnaufer; Sara L. Zimmer; Jason Carnes; Alasdair Ivens; Naghmeh Poorinmohammad; Nicholas J. Savill; Dave Speijer; Ken Stuart; Kristína Záhonová; Poorya Mirzavand Borujeni; Zihao Chen; Cody Goode; Sunil Kumar Sharma; Lars O’Hara; Jorge Cruz-Reyes

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Plasmodium falciparum infection induces T cell tolerance that is associated with decreased disease severity upon re-infection

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2025-04-11

OAAI

Sandoval, Diana Munoz; Bach, Florian A.; Ivens, Alasdair; Harding, Adam C.; Smith, Natasha L.; Mazurczyk, Michalina; Themistocleous, Yrene; Edwards, Nick J.; Silk, Sarah E.; Barrett, Jordan R.; Cowan, Graeme J. M.; Napolitani, Giorgio; Savill, Nicholas J.; Draper, Simon J.; Minassian, Angela M.; Nahrendorf, Wiebke; Spence, Philip J.

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KREH2 helicase represses ND7 mRNA editing in procyclic-stage Trypanosoma brucei by opposite modulation of canonical and 'moonlighting' gRNA utilization creating a proposed mRNA structure

NUCLEIC ACIDS RESEARCH

IF13.1

2024-08-16

OAAI

Meehan, Joshua; Ivens, Alasdair; Grote, Scott; Rodshagen, Tyler; Chen, Zihao; Goode, Cody; Sharma, Sunil K.; Kumar, Vikas; Frese, Addison; Goodall, Zachary; McCleskey, Laura; Sechrist, Rebecca; Zeng, Lanying; Savill, Nicholas J.; Rouskin, Silvi; Schnaufer, Achim; Mcdermott, Suzanne M.; Cruz-Reyes, Jorge

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Trypanosome RNA helicase KREH2 differentially controls non-canonical editing and putative repressive structure via a novel proposed 'bifunctional' gRNA in mRNA A6

NUCLEIC ACIDS RESEARCH

IF13.1

2023-05-29

OAAI

Meehan, Joshua; McDermott, Suzanne M.; Ivens, Alasdair; Goodall, Zachary; Chen, Zihao; Yu, Zihao; Woo, Jia; Rodshagen, Tyler; McCleskey, Laura; Sechrist, Rebecca; Stuart, Kenneth; Zeng, Lanying; Rouskin, Silvi; Savill, Nicholas J.; Schnaufer, Achim; Zhang, Xiuren; Cruz-Reyes, Jorge

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Deep kinetoplast genome analyses result in a novel molecular assay for detecting Trypanosoma brucei gambiense-specific minicircles

genomics proteomics bioinformatics

IF2.8

2022-10-20

OAAI

Geerts, Manon; Chen, Zihao; Bebronne, Nicolas; Savill, Nicholas J.; Schnaufer, Achim; Buscher, Philippe; Van Reet, Nick; Van den Broeck, Frederik

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Organization of minicircle cassettes and guide RNA genes in Trypanosoma brucei

RNA

IF5

2022-04-12

OAAI

Cooper, Sinclair; Wadsworth, Elizabeth S.; Schnaufer, Achim; Savill, Nicholas J.

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Ecological divergence and hybridization of Neotropical Leishmania parasites

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-09-21

OAAI

Van den Broecka, Frederik; Savill, Nicholas J.; Imamura, Hideo; Sanders, Mandy; Maes, Ilse; Cooper, Sinclair; Mateus, David; Jara, Marlene; Adaui, Vanessa; Arevalo, Jorge; Llanos-Cuentas, Alejandro; Garcia, Lineth; Cupolillo, Elisa; Miles, Michael; Berriman, Matthew; Schnaufer, Achim; Cotton, James A.; Dujardia, Jean-Claude

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A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies

NATURE COMMUNICATIONS

IF15.7

2020-03-12

OAAI

Macleod, Olivia J. S.; Bart, Jean-Mathieu; MacGregor, Paula; Peacock, Lori; Savill, Nicholas J.; Hester, Svenja; Ravel, Sophie; Sunter, Jack D.; Trevor, Camilla; Rust, Steven; Vaughan, Tristan J.; Minter, Ralph; Mohammed, Shabaz; Gibson, Wendy; Taylor, Martin C.; Higgins, Matthew K.; Carrington, Mark

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Assembly and annotation of the mitochondrial minicircle genome of a differentiation-competent strain of Trypanosoma brucei

NUCLEIC ACIDS RESEARCH

IF13.1

2019-10-30

OAAI

Cooper, Sinclair; Wadsworth, Elizabeth S.; Ochsenreiter, Torsten; Ivens, Alasdair; Savill, Nicholas J.; Schnaufer, Achim

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Host circadian rhythms are disrupted during malaria infection in parasite genotype-specific manners

SCIENTIFIC REPORTS

IF3.9

2019-07-29

OAAI

Prior, Kimberley F.; O'Donnell, Aidan J.; Rund, Samuel S. C.; Savill, Nicholas J.; van der Veen, Daan R.; Reece, Sarah E.

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The Challenge of Quantifying Synchrony in Malaria Parasites

Trends in Parasitology

IF6.6

2019-05-01

OAAI

Greischar, Megan A.; Reece, Sarah E.; Savill, Nicholas J.; Mideo, Nicole

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Mitochondrial DNA is critical for longevity and metabolism of transmission stage Trypanosoma brucei

PLOS PATHOGENS

IF4.9

2018-07-18

OAAI

Dewar, Caroline E.; MacGregor, Paula; Cooper, Sinclair; Gould, Matthew K.; Matthews, Keith R.; Savill, Nicholas J.; Schnaufer, Achim

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Timing of host feeding drives rhythms in parasite replication

PLOS PATHOGENS

IF4.9

2018-02-26

OAAI

Prior, Kimberley F.; van der Veen, Daan R.; O'Donnell, Aidan J.; Cumnock, Katherine; Schneider, David; Pain, Arnab; Subudhi, Amit; Ramaprasad, Abhinay; Rund, Samuel S. C.; Savill, Nicholas J.; Reece, Sarah E.

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Predicted Impact of Mass Drug Administration on the Development of Protective Immunity against Schistosoma haematobium

PLOS NEGLECTED TROPICAL DISEASES

IF3.4

2014-07-31

OAAI

Mitchell, Kate M.; Mutapi, Francisca; Mduluza, Takafira; Midzi, Nicholas; Savill, Nicholas J.; Woolhouse, Mark E. J.

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The effectiveness of mass vaccination on Marek's disease virus (MDV) outbreaks and detection within a broiler barn: A modeling study

EPIDEMICS

IF2.4

2013-12-01

OAAI

Atkins, Katherine E.; Read, Andrew F.; Walkden-Brown, Stephen W.; Savill, Nicholas J.; Woolhouse, Mark E. J.

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VACCINATION AND REDUCED COHORT DURATION CAN DRIVE VIRULENCE EVOLUTION: MAREK'S DISEASE VIRUS AND INDUSTRIALIZED AGRICULTURE

EVOLUTION

IF2.6

2012-11-04

OAAI

Atkins, Katherine E.; Read, Andrew F.; Savill, Nicholas J.; Renz, Katrin G.; Islam, A. F. M. Fakhrul; Walkden-Brown, Stephen W.; Woolhouse, Mark E. J.

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Protective immunity to Schistosoma haematobium infection is primarily an anti-fecundity response stimulated by the death of adult worms

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2012-07-30

OAAI

Mitchell, Kate M.; Mutapi, Francisca; Savill, Nicholas J.; Woolhouse, Mark E. J.

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Modelling the within-host dynamics of the foot-and-mouth disease virus in cattle

EPIDEMICS

IF2.4

2012-06-01

OAAI

Howey, Richard; Bankowski, Bartlomiej; Juleff, Nicholas; Savill, Nicholas J.; Gibson, Debi; Fazakerley, John; Charleston, Bryan; Woolhouse, Mark E. J.

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Trypanosomal immune evasion, chronicity and transmission: an elegant balancing act

NATURE REVIEWS MICROBIOLOGY

IF103.3

2012-04-30

103

OAAI

MacGregor, Paula; Szoeor, Balazs; Savill, Nicholas J.; Matthews, Keith R.

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Insights into mucosal innate responses to Escherichia coli O157:H7 colonization of cattle by mathematical modelling of excretion dynamics

JOURNAL OF THE ROYAL SOCIETY INTERFACE

IF3.5

2011-08-17

OAAI

Tildesley, Michael J.; Gally, David L.; McNeilly, Tom N.; Low, J. Chris; Mahajan, Arvind; Savill, Nicholas J.

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Research Directions