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S

Sabine Ehrt

Weill Cornell Medical College

65H-index
168Paper Count
1.6WCitation Count
Published Papers 73
Publication Date
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Mycobacterium tuberculosis long-chain fatty acid resistome reveals universal stress protein TB15.3 as essential for infection
errCommunications Biology
IF5.1
err2026-04-19
err0
errOAAI
errAlexandre J. Pinto; Marco Silva; Joana A. Santos; Brian C. VanderVen; Rodrigo Monteiro; Dirk Schnappinger; Sabine Ehrt; Tiago Beites
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A periplasmic protein complex mediates arabinofuranosyltransferase activity and intrinsic drug resistance in Mycobacterium tuberculosis
errScience Advances
IF12.5
err2026-04-01
err0
errOAAI
errThaís Klevorn; Christopher Brown; Christine D. Hardy; Bonnie J. Cuthbert; Amanda Spencer; Adrián Jinich; Luming Chan; Shiva K. Angala; Jordan Manzer; Jessica Mendoza; Rodger de Miranda; Heather Kim; Dirk Schnappinger; Mary Jackson; Kyu Rhee; Celia W. Goulding; Sabine Ehrt
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errSave
Activation of l-histidine biosynthesis as a new antibiotic strategy against Mycobacterium tuberculosis
errNature Communications
IF15.7
err2026-03-21
err0
errOAAI
errDebbie M. Hunt; João Pedro Pisco; Angela Rodgers; Cesira de Chiara; Anisha Zaveri; Kamila L. Pacholarz; Dimitrios Evangelopoulos; Acely Garza-Garcia; Sabine Ehrt; Dirk Schnappinger; Perdita E. Barran; Maximiliano G. Gutierrez; Luiz Pedro S. de Carvalho
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errSave
Reference-based chemical-genetic interaction profiling to elucidate small molecule mechanism of action in Mycobacterium tuberculosis
errNature Communications
IF15.7
err2025-11-03
err0
errOAAI
errAustin N. Bond; Marek Orzechowski; Shuting Zhang; Ishay Ben-Zion; Allison Lemmer; Nathaniel Garry; Katie Lee; Michael Chen; Kayla Delano; Emily Gath; A. Lorelei Golas; Raymond Nietupski; Michael Fitzgerald; Sabine Ehrt; Eric J. Rubin; Christopher M. Sassetti; Dirk Schnappinger; Noam Shoresh; Diana K. Hunt; James E. Gomez; Deborah T. Hung
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errSave
An exacerbated phosphate starvation response triggers Mycobacterium tuberculosis glycerol utilization at acidic pH
errMBIO
IF4.7
err2025-01-08
err0
PREAI
errHealy, Claire; Ehrt, Sabine; Gouzy, Alexandre
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errSave
Interruption of mycothiol synthesis and intracellular redox status impact iron-regulated reporter activation in Mycobacterium smegmatis
errMICROBIOLOGY SPECTRUM
IF3.8
err2024-07-02
err0
errOAAI
errMiller, Alexandra H.; Marks, Frances; Chan, Luming; Botella, Helene; Schnappinger, Dirk; Ehrt, Sabine
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errSave
Mycobacterial biotin synthases require an auxiliary protein to convert dethiobiotin into biotin
errNATURE COMMUNICATIONS
IF15.7
err2024-05-16
err0
errOAAI
errQu, Di; Ge, Peng; Botella, Laure; Park, Sae Woong; Lee, Ha-Na; Thornton, Natalie; Bean, James M.; Krieger, Inna V.; Sacchettini, James C.; Ehrt, Sabine; Aldrich, Courtney C.; Schnappinger, Dirk
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Synthetic lethality of Mycobacterium tuberculosis NADH dehydrogenases is due to impaired NADH oxidation
errMBIO
IF4.7
err2023-12-19
err3
errOAAI
errXu, Yuanyuan; Ehrt, Sabine; Schnappinger, Dirk; Beites, Tiago
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errSave
Differentiating the roles of Mycobacterium tuberculosis substrate binding proteins, FecB and FecB2, in iron uptake
errPLOS PATHOGENS
IF4.9
err2023-09-25
err2
errOAAI
errde Miranda, Rodger; Cuthbert, Bonnie J.; Klevorn, Thais; Chao, Alex; Mendoza, Jessica; Arbing, Mark; Sieminski, Paul J.; Papavinasasundaram, Kadamba; Abdul-Hafiz, Sumer; Chan, Sum; Sassetti, Christopher M.; Ehrt, Sabine; Goulding, Celia W.
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errSave
Metabolically distinct roles of NAD synthetase and NAD kinase define the essentiality of NAD and NADP in Mycobacterium tuberculosis
errMBIO
IF4.7
err2023-06-23
err7
errOAAI
errSharma, Ritu; Hartman, Travis E.; Beites, Tiago; Kim, Jee-Hyun; Eoh, Hyungjin; Engelhart, Curtis A.; Zhu, Linnan; Wilson, Daniel J.; Aldrich, Courtney C.; Ehrt, Sabine; Rhee, Kyu Young; Schnappinger, Dirk
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errSave
Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis
errELIFE
IF0
err2023-02-22
err12
errOAAI
errWong, Andrew, I; Beites, Tiago; Planck, Kyle A.; Fieweger, Rachael A.; Eckartt, Kathryn A.; Li, Shuqi; Poulton, Nicholas C.; VanderVen, Brian C.; Rhee, Kyu Y.; Schnappinger, Dirk; Ehrt, Sabine; Rock, Jeremy
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errSave
Elucidating Iron Transport in the Periplasm of Mycobacterium tuberculosis
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-01-01
err0
errOAAI
errde Miranda, Rodger; Chao, Alex; Klevorn, Thais; Sieminski, Paul; Abdul-Hafiz, Sumer; Ehrt, Sabine; Goulding, Celia
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errSave
A periplasmic cinched protein is required for siderophore secretion and virulence of Mycobacterium tuberculosis
errNATURE COMMUNICATIONS
IF15.7
err2022-04-26
err13
errOAAI
errZhang, Lei; Kent, James E.; Whitaker, Meredith; Young, David C.; Herrmann, Dominik; Aleshin, Alexander E.; Ko, Ying-Hui; Cingolani, Gino; Saad, Jamil S.; Moody, D. Branch; Marassi, Francesca M.; Ehrt, Sabine; Niederweis, Michael
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errSave
CinA mediates multidrug tolerance in Mycobacterium tuberculosis
errNATURE COMMUNICATIONS
IF15.7
err2022-04-22
err24
errOAAI
errKreutzfeldt, Kaj M.; Jansen, Robert S.; Hartman, Travis E.; Gouzy, Alexandre; Wang, Ruojun; Krieger, Inna, V; Zimmerman, Matthew D.; Gengenbacher, Martin; Sarathy, Jansy P.; Xie, Min; Dartois, Veronique; Sacchettini, James C.; Rhee, Kyu Y.; Schnappinger, Dirk; Ehrt, Sabine
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errSave
Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2022-04-05
err21
errOAAI
errKoh, Eun-Ik; Oluoch, Peter O.; Ruecker, Nadine; Proulx, Megan K.; Soni, Vijay; Murphy, Kenan C.; Papavinasasundaram, Kadamba; Reames, Charlotte J.; Trujillo, Carolina; Zaveri, Anisha; Zimmerman, Matthew D.; Aslebagh, Roshanak; Baker, Richard E.; Shaffer, Scott A.; Guinn, Kristine M.; Fitzgerald, Michael; Dartois, Veronique; Ehrt, Sabine; Hung, Deborah T.; Ioerger, Thomas R.; Rubin, Eric J.; Rhee, Kyu Y.; Schnappinger, Dirk; Sassetti, Christopher M.
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errSave
Multiple acyl-CoA dehydrogenase deficiency kills Mycobacterium tuberculosis in vitro and during infection
errNATURE COMMUNICATIONS
IF15.7
err2021-11-15
err17
errOAAI
errBeites, Tiago; Jansen, Robert S.; Wang, Ruojun; Jinich, Adrian; Rhee, Kyu Y.; Schnappinger, Dirk; Ehrt, Sabine
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errSave
Multiform antimicrobial resistance from a metabolic mutation
errSCIENCE ADVANCES
IF12.5
err2021-08-27
err28
errOAAI
errSchrader, Sarah M.; Botella, Helene; Jansen, Robert; Ehrt, Sabine; Rhee, Kyu; Nathan, Carl; Vaubourgeix, Julien
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errSave
Growth of Mycobacterium tuberculosis at acidic pH depends on lipid assimilation and is accompanied by reduced GAPDH activity
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2021-08-02
err40
errOAAI
errGouzy, Alexandre; Healy, Claire; Black, Katherine A.; Rhee, Kyu Y.; Ehrt, Sabine
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errSave
Genetic models of latent tuberculosis in mice reveal differential influence of adaptive immunity
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2021-07-16
err10
errOAAI
errSu, Hongwei; Lin, Kan; Tiwari, Divya; Healy, Claire; Trujillo, Carolina; Liu, Yao; Ioerger, Thomas R.; Schnappinger, Dirk; Ehrt, Sabine
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errSave
Metabolic bifunctionality of Rv0812 couples folate and peptidoglycan biosynthesis in Mycobacterium tuberculosis
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2021-05-05
err6
errOAAI
errBlack, Katherine A.; Duan, Lijun; Mandyoli, Lungelo; Selbach, Bruna P.; Xu, Weizhen; Ehrt, Sabine; Sacchettini, James C.; Rhee, Kyu Y.
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Research Directions

No research directions
Co-authors
Cooperation Journals
S
Shizuo Akira
H-index: 269 · Papers: 1.5K
B
Benjamin F. Cravatt
H-index: 148 · Papers: 867
R
Richard N. Zare
H-index: 137 · Papers: 1.5K
K
Kiyoshi Takeda
H-index: 135 · Papers: 669
C
Carl Nathan
H-index: 127 · Papers: 424
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