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Alternative Polyadenylation Signatures Distinguish Maladaptive Right Ventricular Remodeling in Pulmonary Hypertension: Implications for RNA-Based Diagnostics and Therapeutics Subramaniam, Janani; Jonnakuti, Venkata; Collum, Scott D.; Martineau, Sandra; Huang, Kai-Lieh; Breuils-Bonnet, Sandra; Frump, Andrea L.; Akkanti, Bindu H.; Patel, Jayeshkumar A.; Patel, Manish K.; Salas De Armas, Ismael; Lefebvre, Isabella N.; Radovancevic, Rajko; Blanco, Elvin; Wagner, Eric J.; Gregoric, Igor; Nathan, Sriram; Kar, Biswajit; Provencher, Steeve; Bonnet, Sebastien; Potus, Francois; Yalamanchili, Hari Krishna; Karmouty-Quintana, Harry Share Save
Real-world Persistence on Selexipag for Pulmonary Arterial Hypertension in Canada Weatherald, Jason; Provencher, Steeve; Murray, Jillian; Badin, Matthew; Golden, Shane; Mielniczuk, Lisa; Swiston, John; Zhang, Chang; Yip, Cindy Y. Y.; Mamputu, Jean-Claude; Millson, Brad Share Save
Transitioning From Parenteral Prostanoids to Oral Selexipag in Pulmonary Arterial Hypertension: A Multicenter Retrospective Cohort Study Budhram, Brandon; Alrasheed, Sarah K.; Rashad, Moaaz; Chandy, George; Dvorkin-Gheva, Anna; Fox, George A.; Foxall, Julia; Gardner, Andrea; Helmersen, Doug; Hirani, Naushad; Kemp, Kristina; Kularatne, Mithum; Langleben, David; Lesenko, Lyda; Provencher, Steeve; Spence, Emma; Swiston, John R.; Thakrar, Mitesh; Wadden, Daniel; Weatherald, Jason; Hambly, Nathan Share Save
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Pharmacological inhibition of Epac1 protects against pulmonary fibrosis by blocking FoxO3a neddylation Jankowski, Katherine; Lemay, Sarah E.; Lozano-Ojalvo, Daniel; Perez-Rodriguez, Leticia; Sauvaget, Melanie; Breuils-Bonnet, Sandra; Formoso, Karina; Jagana, Vineeta; Ochoa, Maria T.; Zhang, Shihong; Milara, Javier; Cortijo, Julio; Turnbull, Irene C.; Provencher, Steeve; Bonnet, Sebastien; Ochando, Jordi; Lezoualch, Frank; Bisserier, Malik; Hadri, Lahouaria Share Save
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Unraveling AURKB as a potential therapeutic target in pulmonary hypertension using integrated transcriptomic analysis and pre-clinical studies Lemay, Sarah-Eve; Mougin, Manon; Sauvaget, Melanie; El Kabbout, Reem; Valasarajan, Chanil; Yamamoto, Keiko; Martineau, Sandra; Pelletier, Andreanne; Bilodeau, Coralie; Grobs, Yann; Bourgeois, Alice; Romanet, Charlotte; Breuils-Bonnet, Sandra; Montesinos, Monica S.; Lu, Min; Chen, Huidong; Gilbert, Megan; Theberge, Charlie; Potus, Francois; Pullamsetti, Soni; Provencher, Steeve; Bonnet, Sebastien; Boucherat, Oliver Share Save
ATP citrate lyase drives vascular remodeling in systemic and pulmonary vascular diseases through metabolic and epigenetic changes Grobs, Yann; Romanet, Charlotte; Lemay, Sarah-Eve; Bourgeois, Alice; Voisine, Pierre; Theberge, Charlie; Sauvaget, Melanie; Breuils-Bonnet, Sandra; Martineau, Sandra; El Kabbout, Reem; Valasarajan, Chanil; Chelladurai, Prakash; Pelletier, Andreanne; Mougin, Manon; Dumais, Elizabeth; Perron, Jean; Flamand, Nicolas; Potus, Francois; Provencher, Steeve; Pullamsetti, Soni Savai; Boucherat, Olivier; Bonnet, Sebastien Share Save
Integrin α5β1 represents a novel therapeutic target to improve vascular remodeling in pulmonary arterial hypertension Lemay, Sarah-Eve; Montesinos, Monica; Grobs, Yann; Yokokawa, Tetsuro; Shimauchi, Tsukasa; Romanet, Charlotte; Sauvaget, Melanie; Bonnet, Sandra Breuils; Bourgeois, Alice; Theberge, Charlie; Martineau, Sandra; Lippa, Blaise; Goodwin, Bryan; Lin, Albert; Wang, Hua; Dowling, James; Lu, Min; Qiao, Qi; McTeague, T. Andrew; Moy, Terence I.; Potus, Francois; Provencher, Steeve; Boucherat, Olivier; Bonnet, Sebastien Share Save
Development and characterization of an ex vivo human precision-cut lung slice (hPCLS) system for target validation for pulmonary arterial hypertension Kim, Haejin; Jain, Dhawal; Akram, Muzaffar; Zhou, Willa; Provencher, Steeve; Lemay, Sarah-Eve; Bonnet, Sebastien; Potus, Francois; Montesinos, Monica; Lu, Min; Goodwin, Bryan Share Save
Integrin α5β1 contributes to pathological remodeling of the right ventricle in pulmonary arterial hypertension Lemay, Sarah-Eve; Montesinos, Monica; Grobs, Yann; Bourgeois, Alice; Romanet, Charlotte; Sauvaget, Melanie; Bonnet, Sandra Breuils; Theberge, Charlie; Martineau, Sandra; Lippa, Blaise; Goodwin, Bryan; Lin, Albert; Wang, Hua; Dowling, James; Lu, Min; Qiao, Qi; McTeague, T. Andrew; Moy, Terence I.; Potus, Francois; Provencher, Steeve; Boucherat, Olivier; Bonnet, Sebastien Share Save
Targeting ATP Citrate Lyase: A Novel Therapeutic Strategy for Vascular Remodeling in Pulmonary Hypertension Grobs, Yann; Romanet, Charlotte; Lemay, Sarah-Eve; Bourgeois, Alice; Voisine, Pierre; Theberge, Charlie; Sauvaget, Melanie; Bonnet, Sandra Breuils; Martineau, Sandra; Reem, EL-Kabbout; Pelletier, Andreanne; Mougin, Manon; Dumais, Elizabeth; Perron, Jean; Flamand, Nicolas; Potus, Francois; Provencher, Steeve; Boucherat, Olivier; Bonnet, Sebastien Share Save
Targeting NEK2 to Induce Senescence and DNA Damage in Pulmonary Arterial Hypertension Martineau, Sandra; Yamamoto, Keiko; Bourgeois, Alice; Lemay, Sarah-Eve; Sauvaget, Melanie; Breuils, Sandra Bonnet; Potus, Francois; Provencher, Steeve; Boucherat, Olivier; Bonnet, Sebastien Share Save
Branched Chain Amino Acids Modulate Lung-Liver Axis in Pulmonary Arterial Hypertension Blake, Madelyn; Moon, Ryan; Blake, Jeffrey; Mendelson, Jenna; Annis, Jeffrey; Prisco, Sasha; Provencher, Steeve; Bonnet, Sandra; Brittain, Evan; Bonnet, Sebastien; Prins, Kurt Share Save
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