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Peter J. Greasley

biopharmaceuticals r&d

36H-index
176Paper Count
8.5KCitation Count
Published Papers 69
Publication Date
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New insights from DAPA-CKD indicate dapagliflozin modulates key pathways related to kidney outcomes
errKidney International
IF12.6
err2026-07-27
err0
PREAI
errMark André de la Rambelje; Niels Jongs; Peter J. Greasley; Rasmus Agren; Peter Rossing; David C. Wheeler; Ann Hammarstedt; C. David Sjöström; Adriaan A. Voors; Hiddo J.L. Heerspink
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errSave
Proteins and signalling pathways targeted by dapagliflozin and finerenone: Insights from DAPA-CKD and FIGARO-DKD
errDiabetes, Obesity and Metabolism
IF0
err2025-10-13
err0
errOAAI
errMark André de la Rambelje MSc; Adriaan A. Voors MD; Peter J. Greasley PhD; Mario Berger PhD; Hiddo J. L. Heerspink PhD
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errSave
SGLT2 inhibition triggers aestivation-like metabolic switches for water conservation in patients with heart failure-results from DAPA-Shuttle1, a randomized, placebo-controlled trial
errNephrology Dialysis Transplantation
IF5.6
err2025-10-01
err0
PREAI
errMarton, Adriana; Morisawa, Norihiko; Saffari, Seyed Ehsan; Sim, David; Luft, Friedrich; Greasley, Peter J.; Kitada, Kento; Kovalik, Jean-Paul; Rauh, Manfred; Titze, Jens
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errSave
Protein profiles and associated biological pathways among different aetiologies of chronic kidney disease: new insights from DAPA-CKD
errNephrology Dialysis Transplantation
IF5.6
err2025-10-01
err0
errOAAI
errde la Rambelje, M. Andre; Beldhuis, Iris E.; Heerspink, Hiddo J. L.; Greasley, Peter J.; Agren, Rasmus; Hammarstedt, Ann; Sjostrom, C. David; Voors, Adriaan A.; Jongs, Niels
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errSave
Localization of the therapeutic targets for endothelin receptor antagonists and sodium-glucose co-transporter 2 inhibitors in the chronic liver disease; primary sclerosing cholangitis
errFrontiers in Pharmacology
IF4.8
err2025-09-29
err0
errOAAI
errRhoda E. Kuc; Anna L. Paterson; Thomas L. Williams; William T. H. Gelson; Peter J. Greasley; Phil Ambery; Janet J. Maguire; Anthony P. Davenport
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errSave
A Phase 1b Randomized Clinical Trial of AZD5642 and Dapagliflozin in Patients With Heart Failure and Moderate Renal Impairment
errAMERICAN JOURNAL OF CARDIOLOGY
IF2.1
err2025-09-01
err0
PREAI
errQuintana-Hayashi, Macarena Paz; Connolly, Kathleen; Greasley, Peter; Chan, Melanie; Sadaat, Masood; Svedlund, Sara; Rosenmeier, Jaya Birgitte
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errSave
Effects of combined treatment with zibotentan and dapagliflozin compared to dapagliflozin alone in patients with diabetic and non-diabetic chronic kidney disease
errDIABETES OBESITY & METABOLISM
IF5.7
err2025-05-21
err0
errOAAI
errVictor Wasehuus MD; J. David Smeijer MD; Phil Ambery MD; Peter J. Greasley PhD; Emma Wijkmark MSc; David C. Wheeler MD; Peter Rossing DMSc
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errSave
A multi-omics microbiome signature is associated with the benefits of gastric bypass surgery and is differentiated from diet induced weight loss through 2 years of follow-up
errMucosal Immunology
IF7.6
err2025-04-11
err0
errOAAI
errVancheswaran Gopalakrishnan; Chanchal Kumar; Ida Robertsen; Christopher Morehouse; Ben Sparklin; Shameer Khader; Ian Henry; Line Kristin Johnson; Jens K. Hertel; Hege Christensen; Rune Sandbu; Peter J. Greasley; Bret R. Sellman; Anders Åsberg; Shalini Andersson; Rasmus Jansson Löfmark; Jøran Hjelmesæth; Cecilia Karlsson; Taylor S. Cohen
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errSave
Proteinuria as an End Point in Clinical Trials of Focal Segmental Glomerulosclerosis
errAMERICAN JOURNAL OF KIDNEY DISEASES
IF8.2
err2024-10-01
err0
PREAI
errMariani, LH; Trachtman, H; Thompson, A; Gillespie, BS; Denburg, M; Diva, U; Geetha, D; Greasley, PJ; Hladunewich, MA; Huizinga, RB; Inrig, JK; Komers, R; Laurin, LP; Little, DJ; Nachman, PH; Smith, KA; Walsh, L; Gibson, KL
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errSave
Gastric Bypass vs Diet and Cardiovascular Risk Factors A Nonrandomized Controlled Trial
errJAMA SURGERY
IF14.9
err2024-09-01
err1
errOAAI
errKarlsson, Cecilia; Johnson, Line Kristin; Greasley, Peter J.; Retterstol, Kjetil; Hedberg, Jonatan; Hall, Martin; Hawker, Noele; Robertsen, Ida; Havsol, Jesper; Hertel, Jens Kristoffer; Sandbu, Rune; Skovlund, Eva; Olsen, Thomas; Christensen, Hege; Jansson-Lofmark, Rasmus; Andersson, Shalini; Asberg, Anders; Hjelmesaeth, Joran
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The role of venous capacity in fluid retention with endothelin A antagonism: Mathematical modelling of the RADAR trial
errBRITISH JOURNAL OF PHARMACOLOGY
IF7.7
err2024-08-19
err1
errOAAI
errYu, Hongtao; Greasley, Peter J.; Heerspink, Hiddo J. Lambers; Ambery, Philip; Ahlstrom, Christine; Hamren, Bengt; Khan, Anis A.; Boulton, David W.; Hallow, K. Melissa
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errSave
Effects of Zibotentan Alone and in Combination with Dapagliflozin on Fluid Retention in Patients with CKD
errJOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
IF9.4
err2024-07-12
err3
PREAI
errSmeijer, J. David; Wasehuus, Victor S.; Dhaun, Neeraj; Gorriz, Jose Luis; Soler, Maria Jose; Astrand, Magnus; Mercier, Anne-Kristina; Greasley, Peter J.; Ambery, Phil; Heerspink, Hiddo J. L.
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errSave
From Plan to Pivot: How Model-Informed Drug Development Shaped the Dose Strategy of the Zibotentan/Dapagliflozin ZENITH Trials
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2024-07-03
err0
errOAAI
errMercier, Anne-Kristina; Ueckert, Sebastian; Sunnaker, Mikael; Hamren, Bengt; Ambery, Phil; Greasley, Peter J.; Astrand, Magnus
errShare
errSave
Targeting the endothelium by combining endothelin-1 antagonism and SGLT-2 inhibition: better together?
errCLINICAL SCIENCE
IF7.7
err2024-06-05
err0
errOAAI
errAmbery, Phil; Greasley, Peter J.; Menzies, Robert I.; Brynne, Lena; Kulkarni, Spoorthy; Oscarsson, Jan; Davenport, Anthony P.
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errSave
Co-localization of the sodium-glucose co-transporter-2 channel (SGLT-2) with endothelin ET A and ET B receptors in human cardiorenal tissue
errBIOSCIENCE REPORTS
IF4.7
err2024-05-31
err1
errOAAI
errWilliams, Thomas L.; Kuc, Rhoda E.; Paterson, Anna L.; Abraham, George R.; Pullinger, Anna L.; Maguire, Janet J.; Sinha, Sanjay; Greasley, Peter J.; Ambery, Philip; Davenport, Anthony P.
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errSave
Evaluating clinical outcomes and prognosis in patients with cirrhosis and portal hypertension: a retrospective observational cohort study
errBMJ OPEN GASTROENTEROLOGY
IF2.9
err2023-11-29
err0
errOAAI
errLee, Nerissa Hoi Ching; Kiddle, Steven J.; Chandankhede, Shardul; Agrawal, Shubh; Bean, Daniel M.; Hunt, Phillip R.; Parker, Victoria E. R.; Greasley, Peter J.; Ambery, Philip
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errSave
Effects of dapagliflozin and dapagliflozin-saxagliptin on erythropoiesis, iron and inflammation markers in patients with type 2 diabetes and chronic kidney disease: data from the DELIGHT trial
errCARDIOVASCULAR DIABETOLOGY
IF10.6
err2023-11-28
err3
errOAAI
errKoshino, Akihiko; Neuen, Brendon L.; Jongs, Niels; Pollock, Carol; Greasley, Peter J.; Andersson, Eva-Marie; Hammarstedt, Ann; Karlsson, Cecilia; Langkilde, Anna Maria; Wada, Takashi; Heerspink, Hiddo J. L.
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errSave
Potential Underlying Mechanisms Explaining the Cardiorenal Benefits of Sodium-Glucose Cotransporter 2 Inhibitors
errADVANCES IN THERAPY
IF4
err2023-11-09
err11
errOAAI
errVerma, Subodh; Mudaliar, Sunder; Greasley, Peter J.
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errSave
Current and future strategies for targeting the endothelin pathway in cardiovascular disease
errcardiovascular research
IF10.8
err2023-11-02
err5
errOAAI
errAbraham, George R.; Williams, Thomas L.; Maguire, Janet J.; Greasley, Peter J.; Ambery, Philip; Davenport, Anthony P.
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errSave
Zibotentan in combination with dapagliflozin compared with dapagliflozin in patients with chronic kidney disease (ZENITH-CKD): a multicentre, randomised, active-controlled, phase 2b, clinical trial
errLANCET
IF88.5
err2023-11-01
err50
errOAAI
errHeerspink, Hiddo J. L.; Kiyosue, Arihiro; Wheeler, David C.; Lin, Min; Wijkmark, Emma; Carlson, Glenn; Mercier, Anne-Kristina; Astrand, Magnus; Ueckert, Sebastian; Greasley, Peter J.; Ambery, Phil
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Research Directions

The data has not been retrieved yet.
Co-authors
Cooperation Journals
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John J.V. McMurray
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Naveed Sattar
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Scott D. Solomon
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Piotr Ponikowski
H-index: 179 · Papers: 1.4K
M
Michael Böhm
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