Victor E. Velculescu - Publications, H-index & Citations

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Victor E. Velculescu

johns hopkins university

128H-index

856Paper Count

11.9WCitation Count

Published Papers 187

Publication Date

Cell-free DNA fragmentomes for noninvasive detection of liver cirrhosis and other diseases

Science Translational Medicine

IF14.6

2026-03-04

PREAI

Akshaya V. Annapragada; Zachariah H. Foda; Hope Orjuela; Carter Norton; Shashikant Koul; Noushin Niknafs; Sarah Short; Keerti Boyapati; Adrianna Bartolomucci; Dimitrios Mathios; Michael Noë; Chris Cherry; Jacob Carey; Alessandro Leal; Bryan Chesnick; Nicholas C. Dracopoli; Jamie E. Medina; Nicholas A. Vulpescu; Daniel C. Bruhm; Sarah Bacus; Vilmos Adleff; Amy K. Kim; Stephen B. Baylin; Gregory D. Kirk; Andrei Sorop; Razvan Iacob; Speranta Iacob; Liana Gheorghe; Simona Dima; Manuel Ramírez-Zea; Katherine A. McGlynn; Claus L. Feltoft; Julia S. Johansen; John Groopman; Jillian Phallen; Robert B. Scharpf; Victor E. Velculescu

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Pembrolizumab and epigenetic modification with azacitidine reshapes the tumor microenvironment of platinum-resistant epithelial ovarian cancer: a phase 2 non-randomized clinical trial

Communications Medicine

IF6.3

2026-02-06

OAAI

Blair V. Landon; Julia L. Boland; Andrea E. Wahner Hendrickson; Deborah K. Armstrong; Boris Winterhoff; Jaime Wehr; Akshaya V. Annapragada; Christopher Cherry; Archana Balan; Guneet Kaleka; Victor E. Velculescu; Stephen B. Baylin; Cynthia A. Zahnow; Dennis J. Slamon; Gottfried E. Konecny; Valsamo Anagnostou; John A. Glaspy

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Liquid biopsies across the cancer care continuum

Nature Medicine

IF50

2025-12-10

PREAI

Blair V. Landon; Akshaya V. Annapragada; Noushin Niknafs; Victor E. Velculescu; Valsamo Anagnostou

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NONINVASIVE DETECTION OF GLIOMAS VIA PLASMA CFDNA FRAGMENTOME PROFILING

NEURO-ONCOLOGY

IF13.4

2025-11-01

OAAI

Mathios, Dimitrios; Niknafs, Noushin; Annapragada, Akshaya; Bobeff, Ernest; Park, Chul-Kee; Lim, Michael; Jackson, Christopher; Phallen, Jillian; Scharpf, Robert; Velculescu, Victor

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Phase II study of efficacy and safety of palbociclib in patients with recurrent ovarian cancer

International Journal of Gynecological Cancer

IF4.7

2025-07-28

OAAI

Gottfried E. Konecny; Tara M. Davidson; Coriolan L. Lebreton; Leah A. Marsh; Deandra K. Chetram; Hunter J. Atkinson; Melissa C. Larson; Ann L. Oberg; Nabilah Abdelaal; Jordyn Silverstein; Aminah Jatoi; Anita Washburn; Jill Burton; Sean Dowdy; Liying Zhang; Dorothy Hallberg; Victor E. Velculescu; Dennis J. Slamon; Andrea E. Wahner-Hendrickson

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Combination of pembrolizumab and radiotherapy induces systemic antitumor immune responses in immunologically cold non-small cell lung cancer

Nature Cancer

IF28.5

2025-07-22

OAAI

Justin Huang; Willemijn S. M. E. Theelen; Zineb Belcaid; Mimi Najjar; Daphne van der Geest; Dipika Singh; Christopher Cherry; Archana Balan; James R. White; Jaime Wehr; Rachel Karchin; Noushin Niknafs; Michel M. van den Heuvel; Victor E. Velculescu; Kellie N. Smith; Paul Baas; Valsamo Anagnostou

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Genome-wide analyses of cell-free DNA for therapeutic monitoring of patients with pancreatic cancer

SCIENCE ADVANCES

IF12.5

2025-05-23

PREAI

Hruban, Carolyn; Bruhm, Daniel C.; Chen, Inna M.; Koul, Shashikant; Annapragada, Akshaya V.; Vulpescu, Nicholas A.; Short, Sarah; Theile, Susann; Boyapati, Kavya; Alipanahi, Bahar; Skidmore, Zachary L.; Leal, Alessandro; Cristiano, Stephen; Adleff, Vilmos; Johannsen, Julia S.; Scharpf, Robert B.; Foda, Zachariah H.; Phallen, Jillian; Velculescu, Victor E.

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Genomic and fragmentomic landscapes of cell-free DNA for early cancer detection

NATURE REVIEWS CANCER

IF66.8

2025-03-04

PREAI

Bruhm, Daniel C.; Vulpescu, Nicholas A.; Foda, Zachariah H.; Phallen, Jillian; Scharpf, Robert B.; Velculescu, Victor E.

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Early evaluation of the effectiveness and cost-effectiveness of ctDNA-guided selection for adjuvant chemotherapy in stage II colon cancer

THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY

IF4.2

2024-08-21

OAAI

Kramer, Astrid; Greuter, Marjolein J. E.; Schraa, Suzanna J.; Vink, Geraldine R.; Phallen, Jillian; Velculescu, Victor E.; Meijer, Gerrit A.; van den Broek, Daan; Koopman, Miriam; Roodhart, Jeanine M. L.; Fijneman, Remond J. A.; Retel, Valesca P.; Coupe, Veerle M. H.

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DNA methylation and gene expression as determinants of genome-wide cell-free DNA fragmentation

NATURE COMMUNICATIONS

IF15.7

2024-08-06

OAAI

Noe, Michael; Mathios, Dimitrios; Annapragada, Akshaya V.; Koul, Shashikant; Foda, Zacharia H.; Medina, Jamie E.; Cristiano, Stephen; Cherry, Christopher; Bruhm, Daniel C.; Niknafs, Noushin; Adleff, Vilmos; Ferreira, Leonardo; Easwaran, Hari; Baylin, Stephen; Phallen, Jillian; Scharpf, Robert B.; Velculescu, Victor E.

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Clinical Validation of a Cell-Free DNA Fragmentome Assay for Augmentation of Lung Cancer Early Detection

CANCER DISCOVERY

IF33.3

2024-06-06

OAAI

Mazzone, Peter J.; Bach, Peter B.; Carey, Jacob; Schonewolf, Caitlin A.; Bognar, Katalin; Ahluwalia, Manmeet S.; Cruz-Correa, Marcia; Gierada, David; Kotagiri, Sonali; Lloyd, Kathryn; Maldonado, Fabien; Ortendahl, Jesse D.; Sequist, Lecia V.; Silvestri, Gerard A.; Tanner, Nichole; Thompson, Jeffrey C.; Vachani, Anil; Wong, Kwok-Kin; Zaidi, Ali H.; Catallini, Joseph; Gershman, Ariel; Lumbard, Keith; Millberg, Laurel K.; Nawrocki, Jeff; Portwood, Carter; Rangnekar, Aakanksha; Sheridan, Carolina Campos; Trivedi, Niti; Wu, Tony; Zong, Yuhua; Cotton, Lindsey; Ryan, Allison; Cisar, Christopher; Leal, Alessandro; Dracopoli, Nicholas; Scharpf, Robert B.; Velculescu, Victor E.; Pike, Luke R. G.

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Pushing the Boundaries of Liquid Biopsies for Early Precision Intervention

CANCER DISCOVERY

IF33.3

2024-04-04

OAAI

Anagnostou, Valsamo; Velculescu, Victor E.

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Monitoring treatment response in patients with metastatic colorectal cancer using cfDNA fragmentomics testing: The DOLPHIN trial

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

van Steijn, Denise E.; Fijneman, Remond J.; Vink, Geraldine R.; Roodhart, Jeanine M.; Koopman, Miriam; Lahaye, Max J.; Braat, Manon N. G.; Coupe, Veerle M.; van den Broek, Daan A.; Meijer, Gerrit A.; Wang, Haoyue; Greuter, Marjolein J.; Lissenberg-Witte, Birgit I.; Rinaldi, Lorenzo; Peters, E.; Konicki, Alissa; Dracopoli, Nicholas C.; Kok, Niels F.; Velculescu, Victor E.

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Combined epigenetic therapy and immune checkpoint blockade drive reshaping of the tumor microenvironment of platinum resistant ovarian cancer

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Landon, Blair V.; Kaleka, Guneet; Balan, Archana; Boland, Julia L.; Cherry, Christopher; Pereira, Gavin; Zahnow, Cynthia; Winterhoff, Boris; Baylin, Stephen; Velculescu, Victor E.; Konecny, Gottfried E.; Glaspy, John A.; Anagnostou, Valsamo

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PLASMUT: An R Package for estimating the probability of tumor-specific mutations in cell-free DNA

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Arun, Adith S.; Medina, Jamie E.; Cristiano, Stephen; Bruhm, Daniel C.; Fijneman, Remond J.; Meijer, Gerrit A.; Leal, Alessandro; Velculescu, Victor E.; Scharpf, Robert B.

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DNA methylation and gene expression as determinants of genome-wide cell-free DNA fragmentation

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Noe, Michael; Annapragada, Akshaya V.; Foda, Zachariah H.; Medina, Jamie E.; Mathios, Dimitrios; Cristiano, Stephen; Cherry, Christopher; Bruhm, Daniel C.; Niknafs, Noushin; Adleff, Vilmos; Ferreira, Leonardo; Easwaran, Hari; Baylin, Stephen; Phallen, Jillian; Scharpf, Robert B.; Velculescu, Victor E.

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Clinical validity of post-surgery circulating tumor DNA testing in stage III colon cancer patients treated with adjuvant chemotherapy: The PROVENC3 study

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Alarcon, Carmen Rubio; Georgiadis, Andrew; Franken, Ingrid A.; Wang, Haoyue; van Nassau, Sietske C.; Schraa, Suzanna J.; van der Kruijssen, Dave E.; van Rooijen, Karlijn; Linders, Theodora C.; Delis-van Diemen, Pien; Alkemade, Maartje; Bolijn, Anne; Tijssen, Marianne; Lemmens, Margriet; Meiqari, Lana; Ketelaars, Steven L.; Mosquera, Adria Closa; van Dongen, Miranda M.; Lanfermeijer, Mirthe; Lissenberg-Witte, Birgit I.; Bosch, Linda J.; Bisschop-Snetselaar, Teunise; Adriaans, Bregje; Greer, Amy; Riley, David; White, James R.; Greco, Christopher; Cox, Liam; Fox, Jesse; Victor, Kaitlin; Leech, Catherine; Angiuoli, Samuel V.; Kok, Niels F.; Punt, Cornelis J.; van den Broek, Daan; Koopman, Miriam; Meijer, Gerrit A.; Velculescu, Victor E.; Roodhart, Jeanine M.; Coupe, Veerle M.; Sausen, Mark; Vink, Geraldine R.; Fijneman, Remond J.

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Comparison of FIT and cell-free DNA analyses for detection of individuals with colorectal cancer in population based screening

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Wisse, Pieter Henk Abraham; Rubio-Alarcon, Carmen; Schraa, Suzanna J.; Mosquera, Adria C.; Sausen, Mark; Fijneman, Remond J.; Vink, Geraldine R.; de Wit, Meike; Phallen, Jillian; Velculescu, Victor E.; Carvalho, Beatriz; Meijer, Gerrit A.

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Liquid biopsy approaches for monitoring metastatic pancreatic cancer in immunotherapy treated patients

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Hruban, Carolyn Anna; Chen, Inna; Bruhm, Daniel C.; Koul, Shashikant; Yao, Jennie; Theile, Susann; Boyapati, Kavya; Vulpescu, Nicholas A.; Annapragada, Akshaya; Ferreira, Leonardo; Cristiano, Stephen; Foda, Zachariah H.; Adleff, Vilmos; Johansen, Julia; Phallen, Jillian; Scharpf, Robert B.; Velculescu, Victor E.

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Genome-wide repeat landscapes in cancer and cell-free DNA

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Annapragada, Akshaya; Niknafs, Noushin; White, James R.; Bruhm, Daniel C.; Cherry, Christopher; Medina, Jamie E.; Adleff, Vilmos; Hruban, Carolyn; Mathios, Dimitrios; Foda, Zachariah H.; Phallen, Jillian; Scharpf, Robert B.; Velculescu, Victor E.

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Research Directions