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Alexandre Prat

université de montreal

83H-index
439Paper Count
3.0WCitation Count
Published Papers 187
Publication Date
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Antigen presentation by CD40+MHC-II+ astrocytes promotes CNS autoimmunity
errNature
IF48.5
err2026-08-05
err0
PREAI
errJoon-Hyuk Lee; Zhaorong Li; Joselyn S. Soto; Ah-Ram Kim; Tomer Illouz; Carolina M. Polonio; Michael Kilian; Jessica E. Kenison; Anton M. Schüle; Camilo Faust Akl; Hong-Gyun Lee; Brian M. Andersen; Jessica J. Ye; Joseph M. Rone; Gavin Piester; Lena Srun; Jazmin Martinez; Austin Danko; Jinsu Lee; Tae Hyun Heo; Elizabeth N. Chung; Landon K. Oetjen; Pere Duart-Abadia; Nakyung Koo; Norbert Perrimon; Michael A. Wheeler; Baljit S. Khakh; Stephanie E. J. Zandee; Alexandre Prat; Francisco J. Quintana
errShare
errSave
Causal effects of multiple sclerosis therapies in left-truncated registry data
errMultiple Sclerosis Journal
IF5
err2026-07-21
err0
PREAI
errDagmawi Chilot Haile; Ibrahima Diouf; Serkan Ozakbas; Dana Horakova; Eva Kubala Havrdova; Francesco Patti; Sara Eichau; Raed Alroughani; Alessandra Lugaresi; Valentina Tomassini; Alexandre Prat; Marc Girard; Murat Terzi; Bassem Yamout; Samia J Khoury; Pierre Grammond; Yolanda Blanco; Vahid Shaygannejad; Matteo Foschi; Andrea Surcinelli; Stefano Neri; Bianca Weinstock-Guttman; Julie Prevost; Maria Pia Amato; Michael Barnett; Oliver Gerlach; Nevin John; Allan G Kermode; Marzena Fabis-Pedrini; William M. Carroll; Anneke van der Walt; Helmut Butzkueven; Vincent van Pesch; Aysun Soysal; Riadh Gouider; Saloua Mrabet; Daniele Spitaleri; Elisabetta Cartechini; Davide Maimone; Radek Ampapa; Guy Laureys; Cristina Ramo-Tello; Maria Di Gregorio; Emmanuelle Lapointe; Mark Slee; Rana Karabudak; Justin Garber; Ayse Altintas; Suzanne Hodgkinson; Jose Luis Sanchez-Menoyo; Tamara Castillo-Triviño; Mario Habek; Abdullah Al-Asmi; Talal Al-Harbi; Tunde Csepany; Simón Cárdenas-Robledo; Bruce Taylor; Yi Chao Foong; Barbara Willekens; Nevin Shalaby; Fraser Moore; Chris McGuigan; Seyed Mohammad Baghbanian; Jennifer Massey; Todd A Hardy; Sudarshini Ramanathan; Katrin Gross-Paju; Orla Gray; Danny Decoo; Cameron Shaw; Mihaela Simu; Csilla Rozsa; Elizabeth A Stuart; Sifat Sharmin; Izanne Roos; Tomas Kalincik
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Challenges and future directions for multiple sclerosis after the 2024 McDonald diagnostic criteria
errNature Medicine
IF50
err2026-07-09
err0
PREAI
errJiwon Oh; Frederik Barkhof; Amit Bar-Or; Olga Ciccarrelli; Timothy Coetzee; Massimo Filippi; Cristina Granziera; Yael Hacohen; Bernhard Hemmer; Orhun H. Kantarci; Ho Jin Kim; Christine Lebrun-Frenay; Xavier Montalban; Ellen Mowry; Daniel Ontaneda; Alexandre Prat; Daniel S. Reich; Àlex Rovira; Pascal Sati; Aksel Siva; Andrew J. Solomon; Maria Pia Sormani; Bruno Stankoff; Alan Thompson; Mar Tintore; Anthony Traboulsee; Anneke van der walt; Heinz Wiendl; Peter A. Calabresi
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errSave
First-Line Use of Higher-Efficacy Disease-Modifying Therapies in Multiple Sclerosis: Canadian Consensus Recommendations
errCanadian Journal of Neurological Sciences
IF2.2
err2026-05-19
err0
errOAAI
errMark S. Freedman; Fraser Clift; Virginia Devonshire; François Émond; Catherine Larochelle; Michael C. Levin; Heather MacLean; Sarah A. Morrow; Alexandre Prat; Daniel Selchen
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errSave
Widespread gene-environment interactions shape the immune response to SARS-CoV-2 infection in hospitalized COVID-19 patients
errNature Communications
IF15.7
err2026-04-28
err0
errOAAI
errHaley E. Randolph; Raúl Aguirre-Gamboa; Elsa Brunet-Ratnasingham; Tomoko Nakanishi; Zepeng Mu; Veronica Locher; Ellen Ketter; Cary Brandolino; Catherine Larochelle; Alexandre Prat; Nathalie Arbour; Anne Dumaine; Andrés Finzi; Madeleine Durand; J. Brent Richards; Daniel E. Kaufmann; Luis B. Barreiro
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errSave
Oxidized phosphatidylcholines deposition drives chronic neurodegeneration in a mouse model of progressive multiple sclerosis via IL-1β signaling
errNature Neuroscience
IF20
err2025-12-01
err0
PREAI
errRuoqi Yu; Brian M. Lozinski; Ally Seifert; Khanh Ta; Stephanie Zandee; Deepak K. Kaushik; Jian Park; Wendy Klement; Sandra Larouche; Sotirios Tsimikas; Joseph L. Witztum; Dorian B. McGavern; Alexandre Prat; Yifei Dong
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errSave
Bruton’s tyrosine kinase inhibitors rescue neuronal impairment caused by B cell–mediated lymphotoxin-α release
errScience Translational Medicine
IF14.6
err2025-10-29
err0
PREAI
errJosef Shin; Paul Götz; Nesrin Sharif; Noemi Sola-Sevilla; Camille Grasmuck; Muriel Schraad; Katrin Pape; Muthuraman Muthuraman; Vinzenz Fleischer; Stephanie EJ Zandee; Stefan Bittner; Christina Francisca Vogelaar; Alexandre Prat; Nicholas Hanuscheck; Frauke Zipp
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Disease course after pregnancy in women with progressive multiple sclerosis symptoms
errMultiple Sclerosis Journal
IF5
err2025-09-20
err0
errOAAI
errJessica Shipley; Heidi N Beadnall; Paul G Sanfilippo; Dana Horakova; Cavit Boz; Alexandre Prat; Serkan Ozakbas; Tomas Kalincik; Izanne Roos; Ayse Altintas; Sara Eichau; Olga Skibina; Raed Alroughani; Francesco Patti; Masoud Etemadifar; Alessandra Lugaresi; Valentina Tomassini; Helmut Butzkueven; Anneke van der Walt; Vilija G Jokubaitis
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errSave
Machine learning using clinical variables to screen for depression and anxiety in people with early multiple sclerosis
errMultiple Sclerosis and Related Disorders
IF2.9
err2025-09-17
err0
errOAAI
errBraxton Phillips; Sarah A. Morrow; Harasees Singh; Jiwon Oh; Shannon Kolind; Larry D. Lynd; Alexandre Prat; Roger Tam; Anthony Traboulsee; Scott B. Patten
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errSave
Author Correction: Disease-associated astrocyte epigenetic memory promotes CNS pathology
errNature
IF48.5
err2025-08-26
err0
errOAAI
errHong-Gyun Lee; Joseph M. Rone; Zhaorong Li; Camilo Faust Akl; Seung Won Shin; Joon-Hyuk Lee; Lucas E. Flausino; Florian Pernin; Chun-Cheih Chao; Kilian L. Kleemann; Lena Srun; Tomer Illouz; Federico Giovannoni; Marc Charabati; Liliana M. Sanmarco; Jessica E. Kenison; Gavin Piester; Stephanie E. J. Zandee; Jack P. Antel; Veit Rothhammer; Michael A. Wheeler; Alexandre Prat; Iain C. Clark; Francisco J. Quintana
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errSave
Clinical and mechanistic effects of cladribine in relapsing multiple sclerosis: 2-year results from the MAGNIFY-MS Study
errTherapeutic Advances in Neurological Disorders
IF4.1
err2025-07-31
err0
errOAAI
errKlaus Schmierer; Heinz Wiendl; Frederik Barkhof; Xavier Montalban; Anat Achiron; Tobias Derfuss; Andrew Chan; Suzanne Hodgkinson; Alexandre Prat; Letizia Leocani; Finn Sellebjerg; Patrick Vermersch; Hulin Jin; Laura Sponton; Anita Chudecka; Lidia Gardner; Nicola De Stefano
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errSave
Personalized federated learning for predicting disability progression in multiple sclerosis using real-world routine clinical data
errnpj Digital Medicine
IF15.1
err2025-07-24
err0
errOAAI
errAshkan Pirmani; Edward De Brouwer; Ádám Arany; Martijn Oldenhof; Antoine Passemiers; Axel Faes; Tomas Kalincik; Serkan Ozakbas; Riadh Gouider; Barbara Willekens; Dana Horakova; Eva Kubala Havrdova; Francesco Patti; Alexandre Prat; Alessandra Lugaresi; Valentina Tomassini; Pierre Grammond; Elisabetta Cartechini; Izanne Roos; Cavit Boz; Raed Alroughani; Maria Pia Amato; Katherine Buzzard; Jeannette Lechner-Scott; Joana Guimarães; Claudio Solaro; Oliver Gerlach; Aysun Soysal; Jens Kuhle; Jose Luis Sanchez-Menoyo; Daniele Spitaleri; Tunde Csepany; Bart Van Wijmeersch; Radek Ampapa; Julie Prevost; Samia J. Khoury; Vincent Van Pesch; Nevin John; Davide Maimone; Bianca Weinstock-Guttman; Guy Laureys; Pamela McCombe; Yolanda Blanco; Ayse Altintas; Abdullah Al-Asmi; Justin Garber; Anneke Van der Walt; Helmut Butzkueven; Koen de Gans; Csilla Rozsa; Bruce Taylor; Talal Al-Harbi; Attila Sas; Cecilia Rajda; Orla Gray; Danny Decoo; William M. Carroll; Allan G. Kermode; Marzena Fabis-Pedrini; Deborah Mason; Angel Perez-Sempere; Mihaela Simu; Neil Shuey; Bhim Singhal; Marija Cauchi; Todd A. Hardy; Sudarshini Ramanathan; Patrice Lalive; Carmen-Adella Sirbu; Stella Hughes; Tamara Castillo Trivino; Liesbet M. Peeters; Yves Moreau
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errSave
Four years on: Pregnancy and birth outcomes reported in the MSBase pregnancy, neonatal outcomes, and Women’s Health Registry (2020–2024)
errMultiple Sclerosis Journal
IF5
err2025-07-07
err0
PREAI
errVilija G Jokubaitis; Raed Alroughani; Ayse Altintas; Sara Eichau; Stella Hughes; Barbara Willekens; Dana Horakova; Eva Kubala Havrdova; Serkan Ozakbas; Cavit Boz; Mario Habek; Tomas Kalincik; Izanne Roos; Masoud Etemadifar; Marek Peterka; Jeannette Lechner-Scott; Jose E Meca-Lallana; Zuzana Rous; Jana Houskova; Alexandre Prat; Marc Girard; Radek Ampapa; Katherine Buzzard; Olga Skibina; Nevin A John; Allan G Kermode; Marzena J Fabis-Pedrini; Matteo Foschi; Andrea Surcinelli; Yolanda Blanco; Seyed Mohammad Baghbanian; Oliver Gerlach; Richard Macdonell; Zbysek Pavelek; Pavel Stourac; Pamela McCombe; Guy Laureys; Helmut Butzkueven; Anneke van der Walt; Orla Gray; Marta Vachova; Jana Libertinova; Michael Barnett; Pavel Hradilek; Pierre Duquette; Alena Martinkova; William M Carroll; Eva Recmanova; Julie Prevost; Louise Rath; Guillermo Izquierdo; Abdorreza Naser Moghadasi; Mark Slee; Davide Maimone; Jiwon Oh; Murat Terzi; Pierre Grammond; Jose Luis Sanchez-Menoyo; Emanuele D’Amico; Beatriz Romero Ferrando; Mehmet Fatih Yetkin; Bassem Yamout; Ivana Stetkarova; Cristina Ramo-Tello; Koen de Gans; Riadh Gouider; Saloua Mrabet; Abdullah Al-Asmi; Rana Karabudak; Aysun Soysal; Samia J. Khoury; Emmanuelle Lapointe; Simón Cárdenas-Robledo; Nevin Shalaby; Daniele Spitaleri; Joana Guimarães; Gregor Brecl Jakob; Suzanne Hodgkinson; Mohammad Baghbanian; Recai Turkoglu; Vincent van Pesch; Francois Grand’Maison; Elisabetta Cartechini; Enrique Gomez-Figueroa; Jennifer Massey; Chiyoko Nohara; Kenzo Sakurai; Deborah Mason; Talal Al-Harbi; Tamara Castillo-Triviño; Fumitaka Shimizu; Bruce Taylor; Todd A. Hardy; Steve Vucic; Stephen Reddel; Sudarshini Ramanathan; Danny Decoo; Maria Cecilia Aragon de Vecino; Yuri Nakamura; Norio Chihara; Eli Skromne; Oksana Kopchak
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Summary of Research: Blood Biomarker Dynamics in People with Relapsing Multiple Sclerosis Treated with Cladribine Tablets: Results of the 2-Year MAGNIFY-MS Study
errNeurology and Therapy
IF4.8
err2025-07-04
err0
errOAAI
errHeinz Wiendl; Frederik Barkhof; Xavier Montalban; Anat Achiron; Tobias Derfuss; Andrew Chan; Suzanne Hodgkinson; Alexandre Prat; Letizia Leocani; Klaus Schmierer; Finn Sellebjerg; Patrick Vermersch; Hulin Jin; Anita Chudecka; Andreas Kloetgen; Dongdong Lin; Lidia Gardner; Nicola De Stefano
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errSave
Standardized Definition of Progression Independent of Relapse Activity (PIRA) in Relapsing-Remitting Multiple Sclerosis
errJAMA NEUROLOGY
IF21.3
err2025-06-01
err0
PREAI
errMuller, Jannis; Sharmin, Sifat; Lorscheider, Johannes; Ozakbas, Serkan; Karabudak, Rana; Horakova, Dana; Weinstock-Guttman, Bianca; Shaygannejad, Vahid; Etemadifar, Masoud; Alroughani, Raed; Patti, Francesco; Eichau, Sara; Prat, Alexandre; Tomassini, Valentina; Kermode, Allan G.; Amato, Maria Pia; Turkoglu, Recai; Altintas, Ayse; Buzzard, Katherine; Soysal, Aysun; van der Walt, Anneke; Butzkueven, Helmut; Blanco, Yolanda; Gerlach, Oliver; Khoury, Samia J.; Barnett, Michael; John, Nevin; Lechner-Scott, Jeannette; Surcinelli, Andrea; van Pesch, Vincent; Prevost, Julie; Sa, Maria Jose; Maimone, Davide; D'hooghe, Marie; Hughes, Stella; Hodgkinson, Suzanne; McGuigan, Chris; Cartechini, Elisabetta; Taylor, Bruce; Spitaleri, Daniele; Slee, Mark; McCombe, Pamela; Yamout, Bassem; Benkert, Pascal; Kuhle, Jens; Kappos, Ludwig; Roos, Izanne
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Explainable time-to-progression predictions in multiple sclerosis
errCOMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
IF4.8
err2025-05-01
err0
PREAI
errD'hondt, Robbe; Dedja, Klest; Aerts, Sofie; Van Wijmeersch, Bart; Kalincik, Tomas; Reddel, Stephen; Havrdova, Eva Kubala; Lugaresi, Alessandra; Weinstock-Guttman, Bianca; Mrabet, Saloua; Lalive, Patrice; Kermode, Allan G.; Ozakbas, Serkan; Patti, Francesco; Prat, Alexandre; Tomassini, Valentina; Roos, Izanne; Alroughani, Raed; Gerlach, Oliver; Khoury, Samia J.; van Pesch, Vincent; Sa, Maria Jose; Prevost, Julie; Spitaleri, Daniele; Mccombe, Pamela; Solaro, Claudio; van der Walt, Anneke; Al-Asmi, Helmut Butzkueven Abdullah; Laureys, Guy; Sanchez-Menoyo, Jose Luis; de Gans, Koen; Al-Asmi, Abdullah; Deri, Norma; Csepany, Tunde; Al-Harbi, Talal; Carroll, William M.; Rozsa, Csilla; Singhal, Bhim; Hardy, Todd A.; Ramanathan, Sudarshini; Peeters, Liesbet; Vens, Celine; MSBase Study Grp, MSBase Study
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Blood biomarker dynamics in people with relapsing multiple sclerosis treated with cladribine tablets: results of the 2-year MAGNIFY-MS study
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2025-02-03
err0
errOAAI
errWiendl, Heinz; Barkhof, Frederik; Montalban, Xavier; Achiron, Anat; Derfuss, Tobias; Chan, Andrew; Hodgkinson, Suzanne; Prat, Alexandre; Leocani, Letizia; Schmierer, Klaus; Sellebjerg, Finn; Vermersch, Patrick; Jin, Hulin; Chudecka, Anita; Kloetgen, Andreas; Lin, Dongdong; Gardner, Lidia; De Stefano, Nicola
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First-year treatment response predicts the following 5-year disease course in patients with relapsing-remitting multiple sclerosis
errNEUROTHERAPEUTICS
IF6.9
err2025-02-01
err0
errOAAI
errToscano, Simona; Spelman, Tim; Ozakbas, Serkan; Alroughani, Raed; Chisari, Clara G.; Lo Fermo, Salvatore; Prat, Alexandre; Girard, Marc; Duquette, Pierre; Izquierdo, Guillermo; Eichau, Sara; Grammond, Pierre; Boz, Cavit; Kalincik, Tomas; Blanco, Yolanda; Buzzard, Katherine; Skibina, Olga; Sa, Maria Jose; van der Walt, Anneke; Butzkueven, Helmut; Terzi, Murat; Gerlach, Oliver; Grand'Maison, Francois; Surcinelli, Andrea; Barnett, Michael; Onofrj, Marco; Yamout, Bassem; Khoury, Samia J.; Prevost, Julie; Lechner-Scott, Jeannette; Maimone, Davide; Amato, Maria Pia; Spitaleri, Daniele; Van Pesch, Vincent; Macdonell, Richard; Cartechini, Elisabetta; de Gans, Koen; Slee, Mark; Castillo-Trivino, Tamara; Soysal, Aysun; Sanchez-Menoyo, Jose Luis; Laureys, Guy; Van Hijfte, Liesbeth; Mccombe, Pamela; Altintas, Ayse; Weinstock-Guttman, Bianca; Aguera-Morales, Eduardo; Etemadifar, Masoud; Ramo-Tello, Cristina; John, Nevin; Turkoglu, Recai; Hodgkinson, Suzanne; Besora, Sarah; Fernandez-Bolanos, Ricardo; Patti, Francesco
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Disease-modifying treatment and disability progression in subclasses of patients with primary progressive MS: results from the Big MS Data Network
errJOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
IF7.5
err2024-12-06
err0
errOAAI
errLorscheider, Johannes; Signori, Alessio; Subramaniam, Suvitha; Benkert, Pascal; Vukusic, Sandra; Trojano, Maria; Hillert, Jan; Glaser, Anna; Hyde, Robert; Spelman, Tim; Magyari, Melinda; Elberling, Frederik; Pontieri, Luigi; Koch-Henriksen, Nils; Sorensen, Per Soelberg; Gerlach, Oliver; Prat, Alexandre; Girard, Marc; Eichau, Sara; Grammond, Pierre; Horakova, Dana; Ramo-Tello, Cristina; Roos, Izanne; Buzzard, Katherine; Scott, Jeanette Lechner; Sanchez-Menoyo, Jose Luis; Alroughani, Raed; Prevost, Julie; Kuhle, Jens; Gray, Orla; Mathey, Guillaume; Michel, Laure; Ciron, Jonathan; De Seze, Jerome; Maillart, Elisabeth; Ruet, Aurelie; Labauge, Pierre; Zephir, Helene; Kwiatkowski, Arnaud; van der Walt, Anneke; Kalincik, Tomas; Butzkueven, Helmut; Observatoire Francais de la Sclerose en Plaques OFSEP; MSBase Study Group; Swedish MS Registry; Big MS Data Network
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Disease Activity in Pregnant and Postpartum Women With Multiple Sclerosis Receiving Ocrelizumab or Other Disease-Modifying Therapies
errNEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION
IF7.5
err2024-11-01
err2
errOAAI
errYeh, Wei Z.; van der Walt, Anneke; Skibina, Olga G.; Kalincik, Tomas; Alroughani, Raed; Kermode, Allan G.; Fabis-Pedrini, Marzena J.; Carroll, William M.; Lechner-Scott, Jeannette; Boz, Cavit; Ozakbas, Serkan; Buzzard, Katherine; Habek, Mario; John, Nevin A.; Prat, Alexandre; Girard, Marc; Duquette, Pierre; Baghbanian, Seyed Mohammad; Hodgkinson, Suzanne; Van Pesch, Vincent; Laureys, Guy; Willekens, Barbara; Prevost, Julie; Foschi, Matteo; De Gans, Koen; Horakova, Dana; Havrdova, Eva Kubala; Karabudak, Rana; Patti, Francesco; Mccombe, Pamela A.; Maimone, Davide; Altintas, Ayse; Ampapa, Radek; Spitaleri, Daniele; Gerlach, Oliver H. H.; Sa, Maria Jose; Hughes, Stella; Gouider, Riadh; Mrabet, Saloua; Macdonell, Richard A.; Turkoglu, Recai; Cartechini, Elisabetta; Al-Asmi, Abdullah; Soysal, Aysun; Oh, Jiwon; Muros-Le Rouzic, Erwan; Guye, Sabrina; Pasquarelli, Noemi; Butzkueven, Helmut; Jokubaitis, Vilija G.
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Research Directions

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Co-authors
Cooperation Journals
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Frederik Barkhof
H-index: 179 · Papers: 2.7K
H
Hans Lassmann
H-index: 165 · Papers: 896
L
Ludwig Kappos
H-index: 137 · Papers: 1.3K
A
Andrew T. Chan
H-index: 135 · Papers: 2.2K
L
Lawrence Steinman
H-index: 129 · Papers: 781
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