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E

Eric L. Nuermberger

Medical University of South Carolina

64H-index
267Paper Count
1.2WCitation Count
Published Papers 161
Publication Date
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The role of cytochrome bc1 inhibitors in future tuberculosis treatment regimens
errNature Communications
IF15.7
err2025-10-22
err0
errOAAI
errClara Aguilar-Pérez; Anne J. Lenaerts; Cristina Villellas; Jerome Guillemont; John Dallow; Hannah Painter; Nicole C. Ammerman; Anis Hassan; Guillaume Golovkine; Laure Brock; Sylvie Sordello; Aurélie Chauffour; Alexandra Aubry; Thi Cuc Mai; Sarah Wong; Taane G. Clark; Kiyean Nam; Jeongjun Kim; Jinho Choi; Marjolein Crabbe; Jorge Esquivias; Nacer Lounis; Bart Stoops; Katie Amssoms; Jose M. Bartolome-Nebreda; Veronica Gruppo; Gregory T. Robertson; Nicolas Veziris; Anna M. Upton; Eric L. Nuermberger; Vivian Cox; Lluis Ballell; Benny Baeten; Anil Koul; Alexander S. Pym; Richard J. Wall; Dirk A. Lamprecht
errShare
errSave
Nanofibrous supramolecular peptide hydrogels for controlled release of small-molecule drugs and biologics
errNature Nanotechnology
IF34.9
err2025-09-10
err0
PREAI
errBrett H. Pogostin; Samuel X. Wu; Michael J. Swierczynski; Christopher Pennington; Si-Yang Li; Dilrasbonu Vohidova; Erin H. Seeley; Anushka Agrawal; Chaoyang Tang; Marina H. Yu; Arghadip Dey; Sofia Hernandez; Jacob Cabler; Omid Veiseh; Eric L. Nuermberger; Zachary T. Ball; Jeffrey D. Hartgerink; Kevin J. McHugh
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errSave
A Phase 2a Study of the Early Bactericidal Activity of Rifampicin in Combination With Meropenem Plus Amoxicillin/Clavulanate Among Adults With Rifampicin-Resistant Pulmonary Tuberculosis
errCLINICAL INFECTIOUS DISEASES
IF7.3
err2025-06-01
err0
errOAAI
errde Jager, Veronique; Mockeliunas, Laurynas; You, Huifang; Simonsson, Ulrika S. H.; Collings, Tarryn; Upton, Caryn M.; Bezuidenhout, Johannes A.; Gupte, Nikhil; Dorman, Susan E.; Nuermberger, Eric; Lamichhane, Gyanu; Diacon, Andreas H.; Dooley, Kelly E.
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errSave
The KasA inhibitor JSF-3285 improves the sterilizing activity of bedaquiline-pretomanid-containing regimens in a mouse model of tuberculosis
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2025-04-01
err0
errOAAI
errSoni, Heena; Tyagi, Sandeep; Mane, Kishor; Shelke, Anil M.; Kumar, Pradeep; Kaya, Firat; Alland, David; Zimmerman, Matthew; Freundlich, Joel S.; Nuermberger, Eric L.
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errSave
Efficacy of novel regimens targeting oxidative phosphorylation in Mycobacterium tuberculosis
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2025-04-01
err0
errOAAI
errLi, Dongshuo; Li, Liang; Zhang, Ye; Cheng, Kai; Liang, Wenwen; Nuermberger, Eric; Qi, Xianglong; Fu, Lei; Wang, Bin; Yan, Chenxia; Xu, Rui; Lu, Yu; Xu, Jian
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errSave
Predicting tuberculosis drug efficacy in preclinical and clinical models from in vitro data
errISCIENCE
IF4.1
err2025-03-01
err0
errOAAI
errGoh, Janice J. N.; Patel, Anu; Ngara, Bernard; van Wijk, Rob C.; Strydom, Natasha; Wang, Qianwen; Van, Nhi; Washington, Tracy M.; Nuermberger, Eric L.; Aldridge, Bree B.; Roubert, Christine; Sarathy, Jansy; Dartois, Veronique; Savic, Rada M.
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errSave
Translational Modeling of BTZ-043 to Predict Phase 2A Efficacy and Evaluate Drug-Drug Interactions With Bedaquiline, Pretomanid, and Linezolid in Murine Models
errJOURNAL OF INFECTIOUS DISEASES
IF4.5
err2025-02-17
err0
PREAI
errNgara, Bernard; Flori, Lorenzo; van Wijk, Rob Christiaan; Ernest, Jacqueline P.; Tyagi, Sandeep; Soni, Heena; Hoelscher, Christoph; Walter, Kerstin; Dreisbach, Julia; Hoelscher, Michael; Nuermberger, Eric L.; Savic, Radojka M.
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errSave
Contribution of telacebec to novel drug regimens in a murine tuberculosis model
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2025-01-31
err0
errOAAI
errKomm, Oliver D.; Tyagi, Sandeep; Garcia, Andrew; Almeida, Deepak; Chang, Yong; Li, Si-Yang; Castillo, Jennie Ruelas; Converse, Paul J.; Black, Todd; Fotouhi, Nader; Nuermberger, Eric L.
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errSave
Contribution of direct InhA inhibitors to novel drug regimens in a mouse model of tuberculosis
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2024-11-06
err1
errOAAI
errEncinas, Lourdes; Li, Si-Yang; Rullas-Trincado, Joaquin; Tasneen, Rokeya; Tyagi, Sandeep; Soni, Heena; Garcia-Perez, Adolfo; Lee, Jin; del Rio, Ruben Gonzalez; De Mercado, Jaime; Sousa, Veronica; Sosic, Izidor; Gobec, Stanislav; Mendoza-Losana, Alfonso; Converse, Paul J.; Mdluli, Khisi; Fotouhi, Nader; Barros-Aguirre, David; Nuermberger, Eric L.
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errSave
Prospectively predicting BPaMZ phase IIb/III trial outcomes using a translational mouse-to-human platform
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2024-10-08
err0
errOAAI
errGoh, Janice J. N.; Wang, Qianwen; Zhang, Nan; Suarez, Niurys de Castro; Bustion, Annamarie E.; Nuermberger, Eric L.; Savic, Rada
errShare
errSave
Dose optimization of TBI-223 for enhanced therapeutic benefit compared to linezolid in antituberculosis regimen
errNATURE COMMUNICATIONS
IF15.7
err2024-08-25
err0
errOAAI
errStrydom, Natasha; Ernest, Jacqueline P.; Imperial, Marjorie; Solans, Belen P.; Wang, Qianwen; Tasneen, Rokeya; Tyagi, Sandeep; Soni, Heena; Garcia, Andrew; Bigelow, Kristina; Gengenbacher, Martin; Zimmerman, Matthew; Xie, Min; Sarathy, Jansy P.; Yang, Tian J.; Dartois, Veronique; Nuermberger, Eric L.; Savic, Radojka M.
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errSave
High-Dose Isoniazid Lacks EARLY Bactericidal Activity against Isoniazid-resistant Tuberculosis Mediated by katG Mutations A Randomized Phase II Clinical Trial
errAMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
IF19.4
err2024-08-01
err3
PREAI
errGausi, Kamunkhwala; Ignatius, Elisa H.; De Jager, Veronique; Upton, Caryn; Kim, Soyeon; McKhann, Ashley; Moran, Laura; Wiesner, Lubbe; Von Groote-Bidlingmaier, Florian; Marzinek, Philip; Vanker, Naadira; Yvetot, Joseph; Pierre, Samuel; Rosenkranz, Susan L.; Swindells, Susan; Diacon, Andreas H.; Nuermberger, Eric L.; Denti, Paolo; Dooley, Kelly E.
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errSave
Bactericidal and sterilizing activity of novel regimens combining bedaquiline or TBAJ-587 with GSK2556286 and TBA-7371 in a mouse model of tuberculosis
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2024-04-03
err6
errOAAI
errLi, Si-Yang; Tyagi, Sandeep; Soni, Heena; Betoudji, Fabrice; Converse, Paul J.; Mdluli, Khisimuzi; Upton, Anna M.; Fotouhi, Nader; Barros-Aguirre, David; Ballell, Lluis; Jimenez-Navarro, Elena; Nuermberger, Eric L.
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errSave
Restocking the tuberculosis drug arsenal
errNATURE MEDICINE
IF50
err2024-03-08
err0
PREAI
errNuermberger, Eric L.; Chaisson, Richard E.
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errSave
Contezolid can replace linezolid in a novel combination with bedaquiline and pretomanid in a murine model of tuberculosis
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2023-12-14
err7
errOAAI
errAlmeida, Deepak; Li, Si-Yang; Lee, Jin; Hafkin, Barry; Mdluli, Khisimuzi; Fotouhi, Nader; Nuermberger, Eric L.
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errSave
Bedquiline Resistance Mutations: Correlations with Drug Exposures and Impact on the Proteome in M. tuberculosis
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2023-07-18
err8
errOAAI
errXu, Jian; Li, Dongshuo; Shi, Jinghua; Wang, Bin; Ge, Fei; Guo, Zhenyong; Mu, Xiaopan; Nuermberger, Eric; Lu, Yu
errShare
errSave
Using Dynamic Oral Dosing of Rifapentine and Rifabutin to Simulate Exposure Profiles of Long-Acting Formulations in a Mouse Model of Tuberculosis Preventive Therapy
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2023-07-18
err1
errOAAI
errChang, Yong S.; Li, Si-Yang; Pertinez, Henry; Betoudji, Fabrice; Lee, Jin; Rannard, Steven P.; Owen, Andrew; Nuermberger, Eric L.; Ammerman, Nicole C.
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errSave
Translational predictions of phase 2a first-in-patient efficacy studies for antituberculosis drugs
errEUROPEAN RESPIRATORY JOURNAL
IF21
err2023-06-15
err4
errOAAI
errErnest, Jacqueline P.; Goh, Janice Jia Ni; Strydom, Natasha; Wang, Qianwen; Wijk, Rob C. van; Zhang, Nan; Deitchman, Amelia; Nuermberger, Eric; Savic, Rada M.
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errSave
Next-Generation Diarylquinolines Improve Sterilizing Activity of Regimens with Pretomanid and the Novel Oxazolidinone TBI-223 in a Mouse Tuberculosis Model
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2023-04-18
err24
errOAAI
errLi, Si-Yang; Converse, Paul J. J.; Betoudji, Fabrice; Lee, Jin; Mdluli, Khisimuzi; Upton, Anna; Fotouhi, Nader; Nuermberger, Eric L. L.
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errSave
Mutations in Rv0678 Reduce Susceptibility of Mycobacterium tuberculosis to the DprE1 Inhibitor TBA-7371
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2023-02-14
err7
errOAAI
errAlmeida, Deepak V. V.; Converse, Paul J. J.; Nuermberger, Eric L. L.
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errSave

Research Directions

No research directions
Co-authors
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