Not logged inPharmacoscopy-guided discovery of vortioxetine as a repurposable neuroactive therapeutic for glioblastoma
Lee, Sohyon; Weiss, Tobias; Buhler, Marcel; Mena, Julien; Lottenbach, Zuzanna; Wegmann, Rebekka; Sun, Miaomiao; Bihl, Michel; Augustynek, Bartlomiej; Baumann, Sven P.; Goetze, Sandra; van Drogen, Audrey; Pedrioli, Patrick G. A.; Penton, David; Festl, Yasmin; Buck, Alicia; Kirschenbaum, Daniel; Zeitlberger, Anna M.; Neidert, Marian C.; Vasella, Flavio; Rushing, Elisabeth J.; Wollscheid, Bernd; Hediger, Matthias A.; Weller, Michael; Snijder, Berend .png)
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SaveShare Save A SPATIALLY RESOLVED FUNCTIONAL PROFILING FOR GLIOBLASTOMABuck, A.; Lee, S.; Sakic, I; Wegmann, R.; Mena, J.; Vasella, F.; Friesen, J.; Regli, L.; Le Rhun, E.; Zeitlberger, A.; Tatari, N.; Hutter, G.; Neidert, M.; Weller, M.; Snijder, B.; Weiss, T. Share Save SPATIALLY RESOLVED DRUG SENSITIVITY PROFILING IN GLIOBLASTOMABuck, Alicia; Lee, Sohyon; Wegmann, Rebekka; Mena, Julien; Vasella, Flavio; Friesen, Julia; Regli, Luca; Le Rhun, Emilie; Zeitlberger, Anna Maria; Neidert, Marian Christoph; Tatari, Nazanin; Hutter, Gregor; Weller, Michael; Snijder, Berend; Weiss, Tobias Share Save PHARMACOSCOPY FOR BRAIN METASTASES FROM NON-SMALL CELL LUNG CANCER (NSCLC)Le Rhun, Emilie; Mena, Julien; Lee, Sohyon; Festl, Yasmin; Buck, Alicia; Voglis, Stefanos; Zeitlberger, Anna Maria; Weiss, Tobias; Serra, Carlo; Neidert, Marian; Regli, Luca; Weller, Michael; Snijder, Berend Share Save Enhancing anti-EGFRvIII CAR T cell therapy against glioblastoma with a paracrine SIRPγ-derived CD47 blockerMartins, Tomas A.; Kaymak, Deniz; Tatari, Nazanin; Gerster, Fiona; Hogan, Sabrina; Ritz, Marie-Francoise; Sabatino, Valerio; Wieboldt, Ronja; Bartoszek, Ewelina M.; Mcdaid, Marta; Gerber, Alexandra; Buck, Alicia; Beshirova, Aisha; Heider, Anja; Shekarian, Tala; Mohamed, Hayget; Etter, Manina M.; Schmassmann, Philip; Abel, Ines; Boulay, Jean-Louis; Saito, Yasuyuki; Mariani, Luigi; Guzman, Raphael; Snijder, Berend; Weiss, Tobias; Laeubli, Heinz; Hutter, Gregor Share Save SPATIALLY RESOLVED FUNCTIONAL PROFILING FOR GLIOBLASTOMABuck, A.; Lee, S.; Wegmann, R.; Mena, J.; Vasella, F.; Friesen, J.; Regli, L.; Le Rhun, E.; Zeitlberger, A.; Neidert, M.; Tatari, N.; Hutter, G.; Weller, M.; Snijder, B.; Weiss, T. Share Save High-throughput identification of repurposable neuroactive drugs with potent anti-glioblastoma activityLee, Sohyon; Weiss, Tobias; Buehler, Marcel; Mena, Julien; Lottenbach, Zuzanna; Wegmann, Rebekka; Sun, Miaomiao; Bihl, Michel; Augustynek, Bartlomiej; Baumann, Sven P.; Goetze, Sandra; van Drogen, Audrey; Pedrioli, Patrick G. A.; Penton, David; Festl, Yasmin; Buck, Alicia; Kirschenbaum, Daniel; Zeitlberger, Anna M.; Neidert, Marian C.; Vasella, Flavio; Rushing, Elisabeth J.; Wollscheid, Bernd; Hediger, Matthias A.; Weller, Michael; Snijder, Berend Share Save A prognostic neural epigenetic signature in high-grade gliomaDrexler, Richard; Khatri, Robin; Sauvigny, Thomas; Mohme, Malte; Maire, Cecile L.; Ryba, Alice; Zghaibeh, Yahya; Duehrsen, Lasse; Salviano-Silva, Amanda; Lamszus, Katrin; Westphal, Manfred; Gempt, Jens; Wefers, Annika K.; Neumann, Julia E.; Bode, Helena; Hausmann, Fabian; Huber, Tobias B.; Bonn, Stefan; Juetten, Kerstin; Delev, Daniel; Weber, Katharina J.; Harter, Patrick N.; Onken, Julia; Vajkoczy, Peter; Capper, David; Wiestler, Benedikt; Weller, Michael; Snijder, Berend; Buck, Alicia; Weiss, Tobias; Goeller, Pauline C.; Sahm, Felix; Menstel, Joelle Aline; Zimmer, David Niklas; Keough, Michael B.; Ni, Lijun; Monje, Michelle; Silverbush, Dana; Hovestadt, Volker; Suva, Mario L.; Krishna, Saritha; Hervey-Jumper, Shawn L.; Schueller, Ulrich; Heiland, Dieter H.; Haenzelmann, Sonja; Ricklefs, Franz L. Share Save Affinity fine-tuning anti-CAIX CAR-T cells mitigate on-target off-tumor side effectsWang, Yufei; Buck, Alicia; Piel, Brandon; Zerefa, Luann; Murugan, Nithyassree; Coherd, Christian D.; Miklosi, Andras G.; Johal, Haraman; Bastos, Ricardo Nunes; Huang, Kun; Ficial, Miriam; Laimon, Yasmin Nabil; Signoretti, Sabina; Zhong, Zhou; Hoang, Song-My; Kastrunes, Gabriella M.; Grimaud, Marion; Fayed, Atef; Yuan, Hsien-Chi; Nguyen, Quang-De; Thai, Tran; Ivanova, Elena V.; Paweletz, Cloud P.; Wu, Ming-Ru; Choueiri, Toni K.; Wee, Jon O.; Freeman, Gordon J.; Barbie, David A.; Marasco, Wayne A. Share Save Targeting the Siglec-sialic acid axis promotes antitumor immune responses in preclinical models of glioblastomaSchmassmann, Philip; Roux, Julien; Buck, Alicia; Tatari, Nazanin; Hogan, Sabrina; Wang, Jinyu; Mantuano, Natalia Rodrigues; Wieboldt, Ronja; Lee, Sohyon; Snijder, Berend; Kaymak, Deniz; Martins, Tomas A.; Ritz, Marie-Francoise; Shekarian, Tala; McDaid, Marta; Weller, Michael; Weiss, Tobias; Laeubli, Heinz; Hutter, Gregor Share Save Fine-tuned CAIX targeted CAR-T cells exhibit superior efficacy and mitigate ontarget off-tumor side effectsWang, Yufei; Buck, Alicia; Kastrunes, Gabriella; Abbas, Rabia; Lynch, Michael; Zhong, Zhou; Hoang, Song-My; Miklosi, Andras; Huang, Kun; Cho, Jae-Won; Grimaud, Marion; Razimbaud, Cecile; Chang, Matthew; Fayed, Atef; Apollon, Audrey; Murugan, Nithyassree; Li, Ze-Hua; Thai, Tran; Zerefa, Luann; Piel, Brandon; Ivanova, Elena; Cameron, Amy; Nguyen, Quang-De; Zhu, Zhu; Wei, Kevin; Laimon, Yasmin Nabil Share Save Anti-CAIX BBζ CAR4/8 T cells exhibit superior efficacy in a ccRCC mouse modelWang, Yufei; Buck, Alicia; Grimaud, Marion; Culhane, Aedin C.; Kodangattil, Sreekumar; Razimbaud, Cecile; Bonal, Dennis M.; Quang-De Nguyen; Zhu, Zhu; Wei, Kevin; O'Donnell, Madison L.; Huang, Ying; Signoretti, Sabina; Choueiri, Toni K.; Freeman, Gordon J.; Zhu, Quan; Marasco, Wayne A. Share Save Develop dual-targeted CAR-T cells to achieve RCC curesWang, Yufei; Grimaud, Marion; Buck, Alicia; Fayed, Atef; Chang, Matthew; Jennings, Rebecca; Sticco-Ivins, Maura; Ficial, Miriam; Chan, Leo L.; Signoretti, Sabina; Zhu, Quan; Marasco, Wayne A. Share Save Sensitivity towards the GRP78 inhibitor KP1339/IT-139 is characterized by apoptosis induction via caspase 8 upon disruption of ER homeostasisSchoenhacker-Alte, Beatrix; Mohr, Thomas; Pirker, Christine; Kryeziu, Kushtrim; Kuhn, Paul-Steffen; Buck, Alicia; Hofmann, Thilo; Gerner, Christopher; Hermann, Gerrit; Koellensperger, Gunda; Keppler, Bernhard K.; Berger, Walter; Heffeter, Petra Share Save 
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