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J

Jochen Herms

german center for neurodegenerative diseases

77H-index
493Paper Count
2.2WCitation Count
Published Papers 194
Publication Date
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A reproducible three-dimensional model of human brain tissue to investigate physiological and disease-associated microglia phenotypes
errNature Neuroscience
IF20
err2026-08-04
err0
errOAAI
errJulien Klimmt; Carolina Cardoso Gonçalves; Jessica Valentina Montgomery; Stephan A. Müller; Merle Bublitz; Severin Filser; Lars Paeger; Brigitte Nuscher; Angelika Dannert; Sigrun Roeber; Veronica Pravata; Martina Schifferer; Joshua J. Shrouder; Nathalie Schulz; Judit González-Gallego; Silvia Cappello; Thomas Misgeld; Nikolaus Plesnila; Eduardo Beltrán; Jochen Herms; Elena De Domenico; Marc D. Beyer; Joachim L. Schultze; Christian Haass; Stefan F. Lichtenthaler; Caterina Carraro; Dominik Paquet
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Spatial multi-omics identifies early synaptic pruning and context-specific dopaminergic vulnerability in synucleinopathies
errNature Communications
IF15.7
err2026-07-21
err0
errOAAI
errSvenja-Lotta Rumpf; Felix L. Strübing; Karsten Nalbach; Claudia Marina Vargiu; Giacomo Berg; Stefan F. Lichtenthaler; Piero Parchi; Pan Gao; Weilin Chen; Matthias Brendel; Johannes S. Gnörich; Alexander Bernhardt; Léa Dias Rodrigues; Günter U. Höglinger; Jochen Herms; Thomas Koeglsperger
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Type I interferon drives T cell responses to amyloid beta in the central nervous system
errNature Communications
IF15.7
err2026-04-23
err0
errOAAI
errJulius J. Michel; Khwab Sanghvi; Jakob Rosenbauer; Lea Humbs; Clara Tejido Dierssen; Saskia Grudzenski-Theis; Viktoria Sachs; Kristine Jähne; Karoline Degenhardt; Lutz Frölich; Jochen Herms; Marc Fatar; Michael Platten; Lukas Bunse
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Glucose hypometabolism and hyperphosphorylated Tau synergistically drive neuronal necroptosis
errNeuron
IF15
err2026-04-22
err0
PREAI
errXiaoshi Chen; Sixuan Li; Antonia Neubauer; Xiang Li; Wei Mao; Matthias Brendel; Jixuan Liu; Mengmeng Zhang; Chongzhe Yang; Ruisheng Xu; Jianping Liu; Bing Shan; Junying Yuan; Cong Liu; Jochen Herms; Chengyu Zou
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A repeat expansion in GOLGA8A is a major risk factor for atypical frontotemporal lobar degeneration with ubiquitin-positive inclusions
errNature Genetics
IF29
err2026-03-12
err0
errOAAI
errWouter De Coster; Marleen Van den Broeck; Matt Baker; Nikhil B. Ghayal; Sarah Wynants; Anthony Batzler; Cyril Pottier; Sara Alidadiani; Fahri Küçükali; Gregory D. Jenkins; Rafaela Policarpo; Marka van Blitterswijk; Mariely DeJesus-Hernandez; Alexandra I. Soto-Beasley; Júlia Faura; Elise Coopman; Saskia Hutten; Merel O. Mol; David Wallon; Anne Sieben; Elizabeth C. Finger; Melissa E. Murray; Shelley L. Forrest; Maria C. Tartaglia; Claire Troakes; Jeroen G. J. van Rooij; Aivi T. Nguyen; R. Ross Reichard; Natalie L. Woodman; Alissa L. Nana; Sandra Weintraub; Tamar Gefen; Bart De Vil; Istvan Bodi; Oscar L. Lopez; Susana Boluda; Serge Belliard; Florence Lebert; Florent Marguet; Qinwen Mao; Marsel M. Mesulam; Adam L. Boxer; Mathieu Vandenbulcke; EunRan Suh; Jolien Schaeverbeke; Jean-Charles Lambert; Sonja W. Scholz; Clifton L. Dalgard; Bryan J. Traynor; Raphael J. Gibbs; Gerard D. Schellenberg; Dorothee Dormann; Geert Joris; Tim De Pooter; Peter De Rijk; Svenn D’Hert; Jasper Van Dongen; Julie van der Zee; Mojca Strazisar; Marla Gearing; Thomas Kukar; Margaret Flanagan; Sebastiaan Engelborghs; Bernardino Ghetti; Kathy L. Newell; Andrew King; Sigrun Roeber; Howard J. Rosen; Salvatore Spina; Patrick Cras; Nilüfer Ertekin-Taner; Zbigniew K. Wszolek; Ryan J. Uitti; William P. Cheshire; Wolfgang Singer; Jochen Herms; Keith A. Josephs; Jennifer L. Whitwell; Ronald C. Petersen; Florence Pasquier; Gaël Nicolas; Rudolph Castellani; Jonathan Glass; Bruce L. Miller; Gabor G. Kovacs; Robert A. Rissman; Annie Hiniker; Vincent Deramecourt; Lee-Cyn Ang; Jin Lee-Way; Vivianna M. Van Deerlin; Brittany N. Dugger; Dietmar R. Thal; Lea T. Grinberg; Carlos Cruchaga; Thomas Arzberger; David G. Munoz; Julia Keith; Lorne Zinman; Ekaterina Rogaeva; Edward B. Lee; Stephen J. Haggarty; Olaf Ansorge; Masud Husain; Glenda M. Halliday; Safa Al-Sarraj; Owen A. Ross; Kristel Sleegers; Rik Vandenberghe; Bradley F. Boeve; Neill R. Graff-Radford; Julia Kofler; Charles L. White; Tammaryn Lashley; Manuela Neumann; Joanna M. Biernacka; William W. Seeley; Harro Seelaar; John C. van Swieten; Jonathan D. Rohrer; Dennis W. Dickson; Ian R. A. Mackenzie; Rosa Rademakers
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Constitutive neuronal expression and disease-associated upregulation of chitinases in amyotrophic lateral sclerosis
errBrain
IF11.7
err2026-02-28
err0
PREAI
errNayana Gaur; Christin Angerer; Zeynep I Gunes; Mihai Ancau; Mengzhe Wang; Henrick Riemenschneider; Charlene-Annett Hurler; Simon Mungwa; Patrick Lüningschrör; Anxhela Zhiti; Robert Steinbach; Michael Briese; Mugdha Srivastava; Mario Plaas; Andreas Hermann; Michael Sendtner; Sarah Jäkel; Dieter Edbauer; Jochen Herms; Sabine Liebscher; Julian Grosskreutz; Monika S Brill; null
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Longitudinal monitoring of tau aggregation in progressive supranuclear palsy with [18F]PI-2620 PET
errAlzheimer's & Dementia
IF0
err2026-02-24
err0
errOAAI
errJohannes Gnörich; Julia Kusche-Palenga; Carla Palleis; Antonia Neubauer; Lukas Frontzkowski; Alexander Jäck; Agnes Kling; Theresa Bauer; Hannah Eyob; Katharina Probst; Sebastian N. Roemer-Cassiano; Alexander M. Bernhardt; Sabrina Katzdobler; Lena Marth; Mirlind Zaganjori; Franziska Hopfner; Andreas Zwergal; Jan Häckert; Michael Rullmann; Osama Sabri; Henryk Barthel; Sophia Stöcklein; Rudolf A. Werner; Mikael Simons; Johannes Levin; Jochen Herms; Nicolai Franzmeier; Günter U. Höglinger; Matthias Brendel; for the German Imaging Initiative for Tauopathies (GII4T)
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Accuracy of clinical diagnosis in neurodegenerative diseases - a study of 455 autopsy cases
errJournal of Neurology
IF4.6
err2026-02-20
err0
errOAAI
errJonathan Vöglein; Thomas Arzberger; Irena Ebner; Jochen Herms; Sigrun Roeber; Viktoria Ruf; Adrian Danek; Armin Giese; Günter U. Höglinger; Johannes Levin
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Pioglitazone attenuates complement-mediated microglial synaptic engulfment in an Alzheimer’s disease model
errBrain
IF11.7
err2025-12-15
err0
errOAAI
errJuan Zu; Cong Li; Mochen Cui; Xinwu Liu; Zhouyang Pan; Xiaohe Li; Fang Zhang; Johanna Gentz; Gerda Mitteregger-Kretzschmar; Jochen Herms; Yuan Shi; null
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The Phenotypic Spectrum of Sporadic Creutzfeldt-Jakob Disease Cortical Subtype
errANNALS OF NEUROLOGY
IF7.7
err2025-12-01
err0
errOAAI
errBaiardi, Simone; Vargiu, Claudia Marina; Appleby, Brian S.; Barria, Marcelo; Bentivenga, Giuseppe Mario; Cali, Ignazio; Carla, Benedetta; Cohen, Mark; Giese, Armin; Herms, Jochen; Kortelainen, Aino-minerva; Ladogana, Anna; Mammana, Angela; Ritchie, Diane; Windl, Otto; Capellari, Sabina; Parchi, Piero
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Solitary plasmacytoma of the skull compressing the superior sagittal sinus: Case report and literature review
errBRAIN AND SPINE
IF2.5
err2025-11-01
err0
errOAAI
errHarapan, Biyan Nathanael; Stoecklein, Veit M.; Zimmermann, Hanna; Ruf, Viktoria; Herms, Jochen; Ringel, Florian; Schmutzer-Sondergeld, Michael
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Alpha-synuclein deposition patterns in Alzheimer’s disease: association with cortical amyloid beta and variable tau load
errActa Neuropathologica
IF9.3
err2025-10-30
err0
errOAAI
errAntonia Neubauer; Doris Weissenbrunner; Susanna Pekrun; Sigrun Roeber; Viktoria Ruf; Paul Feyen; Felix L. Strübing; Jochen Herms
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Severe course of tick-borne encephalitis (TBE) in a patient with relapsing multiple sclerosis (MS) treated with ocrelizumab
errMultiple Sclerosis Journal
IF5
err2025-09-11
err0
errOAAI
errJonathan A Gernert; Matthias Klein; Florian Schöberl; Katharina J Müller; Moritz L Schmidbauer; Robert Forbrig; Sigrun Roeber; Jochen Herms; Nicole Terpolilli; Milena Milakovic Obradovic; Alexander Graf; Christopher Dächert; Oliver T Keppler; Maximilian Münchhoff; Konstantinos Dimitriadis
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Brain transcriptomics highlight abundant gene expression and splicing alterations in non-neuronal cells in aFTLD-U
errActa Neuropathologica
IF9.3
err2025-08-10
err0
errOAAI
errSara Alidadiani; Júlia Faura; Sarah Wynants; Nele Peeters; Marleen Van den Broeck; Linus De Witte; Rafaela Policarpo; Simon Cheung; Cyril Pottier; Nikhil B. Ghayal; Merel O. Mol; Marka van Blitterswijk; Evan Udine; Mariely DeJesus-Hernandez; Matthew Baker; NiCole A. Finch; Yan W. Asmann; Jeroen G. J. van Rooij; Aivi T. Nguyen; R. Ross Reichard; Alissa L. Nana; Oscar L. Lopez; Adam L. Boxer; Howard J. Rosen; Salvatore Spina; Jochen Herms; Keith A. Josephs; Ronald C. Petersen; Robert A. Rissman; Annie Hiniker; Lee-Cyn Ang; Lea T. Grinberg; Glenda M. Halliday; Bradley F. Boeve; Neill R. Graff-Radford; Harro Seelaar; Manuela Neumann; Julia Kofler; Charles L. White; William W. Seeley; John C. van Swieten; Dennis W. Dickson; Ian R. A. Mackenzie; Wouter De Coster; Rosa Rademakers
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Early Locus Coeruleus noradrenergic axon loss drives olfactory dysfunction in Alzheimer’s disease
errNature Communications
IF15.7
err2025-08-08
err0
errOAAI
errCarolin Meyer; Theresa Niedermeier; Paul L. C. Feyen; Felix L. Strübing; Boris-Stephan Rauchmann; Katerina Karali; Johanna Gentz; Yannik E. Tillmann; Nicolas F. Landgraf; Svenja-Lotta Rumpf; Katharina Ochs; Karin Wind-Mark; Gloria Biechele; Jessica Wagner; Selim Guersel; Carolin I. Kurz; Meike Schweiger; Danilo Prtvar; Yuan Shi; Richard B. Banati; Guo-Jun Liu; Ryan J. Middleton; Gerda Mitteregger-Kretzschmar; Robert Perneczky; Thomas Koeglsperger; Jonas J. Neher; Sabina Tahirovic; Matthias Brendel; Jochen Herms; Lars Paeger
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Cellular hierarchies of embryonal tumors with multilayered rosettes are shaped by oncogenic microRNAs and receptor-ligand interactions
errNATURE CANCER
IF28.5
err2025-05-26
err0
errOAAI
errBeck, Alexander; Gabler-Pamer, Lisa; Alencastro Veiga Cruzeiro, Gustavo; Lambo, Sander; Englinger, Bernhard; Shaw, McKenzie L.; Hack, Olivia A.; Liu, Ilon; Haase, Rebecca D.; de Biagi Jr, Carlos A. O.; Baumgartner, Alicia; Nascimento Silva, Andrezza Do; Klenner, Marbod; Freidel, Pia S.; Herms, Jochen; von Baumgarten, Louisa; Tonn, Joerg C.; Thon, Niklas; Bruckner, Katharina; Madlener, Sibylle; Mayr, Lisa; Senfter, Daniel; Peyrl, Andreas; Slavc, Irene; Loetsch, Daniela; Dorfer, Christian; Geyregger, Rene; Amberg, Nicole; Haberler, Christine; Mack, Norman; Schwalm, Benjamin; Pfister, Stefan M.; Korshunov, Andrey; Baird, Lissa C.; Yang, Edward; Chi, Susan N.; Alexandrescu, Sanda; Gojo, Johannes; Kool, Marcel; Hovestadt, Volker; Filbin, Mariella G.
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Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing
errNATURE COMMUNICATIONS
IF15.7
err2025-04-25
err0
errOAAI
errPottier, Cyril; Kuecuekali, Fahri; Baker, Matt; Batzler, Anthony; Jenkins, Gregory D.; van Blitterswijk, Marka; Vicente, Cristina T.; De Coster, Wouter; Wynants, Sarah; van de Walle, Pieter; Ross, Owen A.; Murray, Melissa E.; Faura, Julia; Haggarty, Stephen J.; van Rooij, Jeroen GJ.; Mol, Merel O.; Hsiung, Ging-Yuek R.; Graff, Caroline; Oeijerstedt, Linn; Neumann, Manuela; Asmann, Yan; Mcdonnell, Shannon K.; Baheti, Saurabh; Josephs, Keith A.; Whitwell, Jennifer L.; Bieniek, Kevin F.; Forsberg, Leah; Heuer, Hilary; Lago, Argentina Lario; Geier, Ethan G.; Yokoyama, Jennifer S.; Oddi, Alexis P.; Flanagan, Margaret; Mao, Qinwen; Hodges, John R.; Kwok, John B.; Domoto-Reilly, Kimiko; Synofzik, Matthis; Wilke, Carlo; Onyike, Chiadi; Dickerson, Bradford C.; Evers, Bret M.; Dugger, Brittany N.; Munoz, David G.; Keith, Julia; Zinman, Lorne; Rogaeva, Ekaterina; Suh, Eunran; Gefen, Tamar; Geula, Changiz; Weintraub, Sandra; Diehl-Schmid, Janine; Farlow, Martin R.; Edbauer, Dieter; Woodruff, Bryan K.; Caselli, Richard J.; Donker Kaat, Laura L.; Huey, Edward D.; Reiman, Eric M.; Mead, Simon; King, Andrew; Roeber, Sigrun; Nana, Alissa L.; Ertekin-Taner, Nilufer; Knopman, David S.; Petersen, Ronald C.; Petrucelli, Leonard; Uitti, Ryan J.; Wszolek, Zbigniew K.; Ramos, Eliana Marisa; Grinberg, Lea T.; Tempini, Maria Luisa Gorno; Rosen, Howard J.; Spina, Salvatore; Piguet, Olivier; Grossman, Murray; Trojanowski, John Q.; Keene, C. Dirk; Jin, Lee-Way; Prudlo, Johannes; Geschwind, Daniel H.; Rissman, Robert A.; Cruchaga, Carlos; Ghetti, Bernardino; Halliday, Glenda M.; Beach, Thomas G.; Serrano, Geidy E.; Arzberger, Thomas; Herms, Jochen; Boxer, Adam L.; Honig, Lawrence S.; Vonsattel, Jean P.; Lopez, Oscar L.; Kofler, Julia; White, Charles L.; Gearing, Marla; Glass, Jonathan; Rohrer, Jonathan D.; Irwin, David J.; Lee, Edward B.; Van Deerlin, Vivianna; Castellani, Rudolph; Mesulam, Marsel M.; Tartaglia, Maria C.; Finger, Elizabeth C.; Troakes, Claire; Al-Sarraj, Safa; Dalgard, Clifton L.; Miller, Bruce L.; Seelaar, Harro; Graff-Radford, Neill R.; Boeve, Bradley F.; Mackenzie, Ian RA.; van Swieten, John C.; Seeley, William W.; Sleegers, Kristel; Dickson, Dennis W.; Biernacka, Joanna M.; Rademakers, Rosa
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BENZODIAZEPINE DIAZEPAM INDUCES COGNITIVE IMPAIRMENT VIA TRANSLOCATOR PROTEIN (18 KDA): IMPLICATIONS ON DEMENTIA
errINTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
IF3.7
err2025-02-12
err0
errOAAI
errShi, Yuan; Cui, Mochen; Herms, Jochen
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Myeloid cell-specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2024-12-04
err0
PREAI
errDinkel, Lina; Hummel, Selina; Zenatti, Valerio; Malara, Mariagiovanna; Tillmann, Yannik; Colombo, Alessio; Monasor, Laura Sebastian; Suh, Jung H.; Logan, Todd; Roth, Stefan; Paeger, Lars; Hoffelner, Patricia; Bludau, Oliver; Schmidt, Andree; Mueller, Stephan A.; Schifferer, Martina; Nuscher, Brigitte; Njavro, Jasenka Rudan; Prestel, Matthias; Bartos, Laura M.; Wind-Mark, Karin; Slemann, Luna; Hoermann, Leonie; Kunte, Sebastian T.; Gnoerich, Johannes; Lindner, Simon; Simons, Mikael; Herms, Jochen; Paquet, Dominik; Lichtenthaler, Stefan F.; Bartenstein, Peter; Franzmeier, Nicolai; Liesz, Arthur; Grosche, Antje; Bremova-Ertl, Tatiana; Catarino, Claudia; Beblo, Skadi; Bergner, Caroline; Schneider, Susanne A.; Strupp, Michael; Di Paolo, Gilbert; Brendel, Matthias; Tahirovic, Sabina
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Neuronal and oligodendroglial, but not astroglial, tau translates to in vivo tau PET signals in individuals with primary tauopathies
errACTA NEUROPATHOLOGICA
IF9.3
err2024-11-24
err0
errOAAI
errSlemann, L; Gnörich, J; Hummel, S; Bartos, LM; Klaus, C; Kling, A; Kusche-Palenga, J; Kunte, ST; Kunze, LH; Englert, AL; Li, YL; Vogler, L; Katzdobler, S; Palleis, C; Bernhardt, A; Jäck, A; Zwergal, A; Hopfner, F; Roemer-Cassiano, SN; Biechele, G; Stöcklein, S; Bischof, G; van Eimeren, T; Drzezga, A; Sabri, O; Barthel, H; Respondek, G; Grimmer, T; Levin, J; Herms, J; Paeger, L; Willroider, M; Beyer, L; Höglinger, GU; Roeber, S; Franzmeier, N; Brendel, M
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Research Directions

No research directions
Co-authors
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