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Genetic mapping across autoimmune diseases reveals shared associations and mechanisms Lincoln, Matthew R.; Connally, Noah; Axisa, Pierre-Paul; Gasperi, Christiane; Mitrovic, Mitja; van Heel, David; Wijmenga, Cisca; Withoff, Sebo; Jonkers, Iris H.; Padyukov, Leonid; Beecham, Ashley H.; Patsopoulos, Nikolaos A.; Cotsapas, Chris; Booth, David; Goris, An; Oturai, Annette; Saarela, Janna; Fontaine, Betrand; Hemmer, Bertrand; Claes, Martin; Zipp, Frauke; D'Alfonso, Sandra; Martinelli-Boneschi, Filippo; Taylor, Bruce; Harbo, Hanne F.; Kockum, Ingrid; Hillert, Jan; Olsson, Tomas; Oksenberg, Jorge R.; Hintzen, Rogier; Barcellos, Lisa F.; Alfredsson, Lars; Esposito, Federica; Martin, Roland; Haines, Jonathan L.; Pericak-Vance, Margaret A.; Ivinson, Adrian J.; Stewart, Graeme; Hafler, David; Hauser, Stephen L.; Compston, Alastair; Mcvean, Gil; De Jager, Philip; Sawcer, Stephen J.; Mccauley, Jakob L.; Rich, Stephen S.; Graham, Robert R.; Gaffney, Patrick M.; Langefeld, Carl D.; Vyse, Timothy J.; Hafler, David A.; Chun, Sung; Sunyaev, Shamil R.; Cotsapas, Chris Share Save
High-resolution African HLA resource uncovers HLA-DRB1 expression effects underlying vaccine response Mentzer, Alexander J.; Dilthey, Alexander T.; Pollard, Martin; Gurdasani, Deepti; Karakoc, Emre; Carstensen, Tommy; Muhwezi, Allan; Cutland, Clare; Diarra, Amidou; Antunes, Ricardo da Silva; Paul, Sinu; Smits, Gaby; Wareing, Susan; Kim, Hwaran; Pomilla, Cristina; Chong, Amanda Y.; Brandt, Debora Y. C.; Nielsen, Rasmus; Neaves, Samuel; Timpson, Nicolas; Crinklaw, Austin; Arlehamn, Cecilia S. Lindestam; Rautanen, Anna; Kizito, Dennison; Parks, Tom; Auckland, Kathryn; Elliott, Kate E.; Mills, Tara; Ewer, Katie; Edwards, Nick; Fatumo, Segun; Webb, Emily; Peacock, Sarah; Jeffery, Katie; van der Klis, Fiona R. M.; Kaleebu, Pontiano; Vijayanand, Pandurangan; Peters, Bjorn; Sette, Alessandro; Cereb, Nezih; Sirima, Sodiomon; Madhi, Shabir A.; Elliott, Alison M.; Mcvean, Gil; Hill, Adrian V. S.; Sandhu, Manjinder S. Share Save
A common NFKB1 variant detected through antibody analysis in UK Biobank predicts risk of infection and allergy Chong, Amanda Y.; Brenner, Nicole; Jimenez-Kaufmann, Andres; Cortes, Adrian; Hill, Michael; Littlejohns, Thomas J.; Gilchrist, James J.; Fairfax, Benjamin P.; Knight, Julian C.; Hodel, Flavia; Fellay, Jacques; Mcvean, Gil; Moreno-Estrada, Andres; Waterboer, Tim; Hill, Adrian V. S.; Mentzer, Alexander J. Share Save
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Mouse fetal growth restriction through parental and fetal immune gene variation and intercellular communications cascade Kaur, Gurman; Porter, Caroline B. M.; Ashenberg, Orr; Lee, Jack; Riesenfeld, Samantha J.; Hofree, Matan; Aggelakopoulou, Maria; Subramanian, Ayshwarya; Kuttikkatte, Subita Balaram; Attfield, Kathrine E.; Desel, Christiane A. E.; Davies, Jessica L.; Evans, Hayley G.; Avraham-Davidi, Inbal; Nguyen, Lan T.; Dionne, Danielle A.; Neumann, Anna E.; Jensen, Lise Torp; Barber, Thomas R.; Soilleux, Elizabeth; Carrington, Mary; McVean, Gil; Rozenblatt-Rosen, Orit; Regev, Aviv; Fugger, Lars Share Save
Identification of host-pathogen-disease relationships using a scalable multiplex serology platform in UK Biobank Mentzer, Alexander J.; Brenner, Nicole; Allen, Naomi; Littlejohns, Thomas J.; Chong, Amanda Y.; Cortes, Adrian; Almond, Rachael; Hill, Michael; Sheard, Simon; McVean, Gil; Collins, Rory; Hill, Adrian V. S.; Waterboer, Tim Share Save
Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders Eijsbouts, Chris; Zhen, Tenghao; Kennedy, Nicholas A.; Bonfiglio, Ferdinando; Anderson, Carl A.; Moutsianas, Loukas; Holliday, Joanne; Shi, Jingchunzi; Shringarpure, Suyash; Voda, Alexandru-loan; Farrugia, Gianrico; Franke, Andre; Huebenthal, Matthias; Abecasis, Goncalo; Zawistowski, Matthew; Skogholt, Anne Heidi; Ness-Jensen, Eivind; Hveem, Kristian; Esko, Tonu; Teder-Laving, Maris; Zhernakova, Alexandra; Camilleri, Michael; Boeckxstaens, Guy; Whorwell, Peter J.; Spiller, Robin; McVean, Gil; D'Amato, Mauro; Jostins, Luke; Parkes, Miles Share Save
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Detection of simple and complex de novo mutations with multiple reference sequences Garimella, Kiran, V; Iqbal, Zamin; Krause, Michael A.; Campino, Susana; Kekre, Mihir; Drury, Eleanor; Kwiatkowski, Dominic; Sa, Juliana M.; Wellems, Thomas E.; McVean, Gil Share Save
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The origins and relatedness structure of mixed infections vary with local prevalence of P. falciparum malaria Zhu, Sha Joe; Hendry, Jason A.; Almagro-Garcia, Jacob; Pearson, Richard D.; Amato, Roberto; Miles, Alistair; Weiss, Daniel J.; Lucas, Tim C. D.; Nguyen, Michele; Gething, Peter W.; Kwiatkowski, Dominic; McVean, Gil Share Save
Mapping the drivers of within-host pathogen evolution using massive data sets Palmer, Duncan S.; Turner, Isaac; Fidler, Sarah; Frater, John; Goedhals, Dominique; Goulder, Philip; Huang, Kuan-Hsiang Gary; Oxenius, Annette; Phillips, Rodney; Shapiro, Roger; van Vuuren, Cloete; McLean, Angela R.; McVean, Gil Share Save
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Genomic Analysis of Plasmodium vivax in Southern Ethiopia Reveals Selective Pressures in Multiple Parasite Mechanisms Auburn, Sarah; Getachew, Sisay; Pearson, Richard D.; Amato, Roberto; Miotto, Olivo; Trimarsanto, Hidayat; Zhu, Sha Joe; Rumaseb, Angela; Marfurt, Jutta; Noviyanti, Rintis; Grigg, Matthew J.; Barber, Bridget; William, Timothy; Goncalves, Sonia Morgado; Drury, Eleanor; Sriprawat, Kanlaya; Anstey, Nicholas M.; Nosten, Francois; Petros, Beyene; Aseffa, Abraham; McVean, Gil; Kwiatkowski, Dominic P.; Price, Ric N. Share Save
A point mutation in the ion conduction pore of AMPA receptor GRIA3 causes dramatically perturbed sleep patterns as well as intellectual disability Davies, Benjamin; Brown, Laurence A.; Cais, Ondrej; Watson, Jake; Clayton, Amber J.; Chang, Veronica T.; Biggs, Daniel; Preece, Christopher; Hernandez-Pliego, Polinka; Krohn, Jon; Bhomra, Amarjit; Twigg, Stephen R. F.; Rimmer, Andrew; Kanapin, Alexander; Sen, Arjune; Zaiwalla, Zenobia; McVean, Gil; Foster, Russell; Donnelly, Peter; Taylor, Jenny C.; Blair, Edward; Nutt, David; Aricescu, A. Radu; Greger, Ingo H.; Peirson, Stuart N.; Flint, Jonathan; Martin, Hilary C. Share Save
Structural and regulatory diversity shape HLA-C protein expression levels Kaur, Gurman; Gras, Stephanie; Mobbs, Jesse I.; Vivian, Julian P.; Cortes, Adrian; Barber, Thomas; Kuttikkatte, Subita Balaram; Jensen, Lise Torp; Attfield, Kathrine E.; Dendrou, Calliope A.; Carrington, Mary; McVean, Gil; Purcell, Anthony W.; Rossjohn, Jamie; Fugger, Lars Share Save
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