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H

Holger Heyn

Universidade da Coruna

68H-index
302Paper Count
2.1WCitation Count
Published Papers 106
Publication Date
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Publisher Correction: Interpretable inflammation landscape of circulating immune cells
errNature Medicine
IF50
err2026-01-26
err0
errOAAI
errLaura Jiménez-Gracia; Davide Maspero; Sergio Aguilar-Fernández; Francesco Craighero; Maria Boulougouri; Max Ruiz; Domenica Marchese; Ginevra Caratù; Jose Liñares-Blanco; Miren Berasategi; Ricardo O. Ramirez Flores; Angela Sanzo-Machuca; Ana M. Corraliza; Hoang A. Tran; Rachelly Normand; Jacquelyn Nestor; Yourae Hong; Tessa Kole; Petra van der Velde; Frederique Alleblas; Flaminia Pedretti; Adrià Aterido; Martin Banchero; German Soriano; Eva Román; Maarten van den Berge; Azucena Salas; Jose Manuel Carrascosa; Antonio Fernández Nebro; Eugeni Domènech; Juan D. Cañete; Jesús Tornero; Javier P. Gisbert; Ernest Choy; Giampiero Girolomoni; Britta Siegmund; Antonio Julià; Violeta Serra; Roberto Elosua; Sabine Tejpar; Silvia Vidal; Martijn C. Nawijn; Ivo Gut; Julio Saez-Rodriguez; Sara Marsal; Alexandra-Chloé Villani; Juan C. Nieto; Holger Heyn
errShare
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Interpretable inflammation landscape of circulating immune cells
errNature Medicine
IF50
err2026-01-12
err0
errOAAI
errLaura Jiménez-Gracia; Davide Maspero; Sergio Aguilar-Fernández; Francesco Craighero; Maria Boulougouri; Max Ruiz; Domenica Marchese; Ginevra Caratù; Jose Liñares-Blanco; Miren Berasategi; Ricardo O. Ramirez Flores; Angela Sanzo-Machuca; Ana M. Corraliza; Hoang A. Tran; Rachelly Normand; Jacquelyn Nestor; Yourae Hong; Tessa Kole; Petra van der Velde; Frederique Alleblas; Flaminia Pedretti; Adrià Aterido; Martin Banchero; German Soriano; Eva Román; Maarten van den Berge; Azucena Salas; Jose Manuel Carrascosa; Antonio Fernández Nebro; Eugeni Domènech; Juan Cañete; Jesús Tornero; Javier P. Gisbert; Ernest Choy; Giampiero Girolomoni; Britta Siegmund; Antonio Julià; Violeta Serra; Roberto Elosua; Sabine Tejpar; Silvia Vidal; Martijn C. Nawijn; Ivo Gut; Julio Saez-Rodriguez; Sara Marsal; Alexandra-Chloé Villani; Juan C. Nieto; Holger Heyn
errShare
errSave
Architecture of the neutrophil compartment
errNature
IF48.5
err2025-12-03
err0
errOAAI
errDaniela Cerezo-Wallis; Andrea Rubio-Ponce; Mathis Richter; Emanuele Pitino; Immanuel Kwok; Giovanni Marteletto; Ana Cristina Guanolema-Coba; Changming Shih; Run-Kai Huang; Ana Moraga; Natalia Borbaran Bravo; Samuel Doré; Sergio Callejas; David G. Aragonés; Daniel Jiménez-Carretero; Daniel Martin; Samuel Ovadia; Tommaso Vicanolo; Georgiana Crainiciuc; Jon Sicilia; Tong Deng; Anjelica Martin; Jing Zhang; Maria Isabel Cuartero; Diego Moncada Giraldo; Alicia Garcia-Culebras; Alejandra Aroca-Crevillen; Sandra Martín-Salamanca; Carlos Torroja; Max Ruiz; Irene Ruano; Melissa S. F. Ng; Jian Hou; You Wang; Ming Zhang; Jun Pu; Ana Herruzo; David Chang van Oordt; Seokyoon Chang; Alexander E. Downie; Fei Chen; Andrea L. Graham; William C. Gause; Pierre O. Fiset; Jonathan D. Spicer; Holger Heyn; Maria A. Zuriaga; Juan A. Bernal; Irina A. Udalova; Maria A. Moro; Katrien de Bock; Ana Dopazo; Jose J. Fuster; Fátima Sánchez-Cabo; Juan C. Nieto; Gabriel F. Calvo; Julia Skokowa; Oliver Soehnlein; Daniela F. Quail; Logan A. Walsh; Lai Guan Ng; Andrés Hidalgo; Iván Ballesteros
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errSave
Role of CEBPa in trophectoderm competence installment
errScience Advances
IF12.5
err2025-11-28
err0
PREAI
errXiao Wei; Irepan Salvador-Martinez; Maciej Meglicki; Marcos Plana-Carmona; Antonios Klonizakis; Barbara Pernaute; Manuel Irimia; Gregoire Stik; Mina Popovic; Guillem Torcal Garcia; Holger Heyn; Magdalena Zernicka-Goetz; Thomas Graf
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errSave
TGF-β builds a dual immune barrier in colorectal cancer by impairing T cell recruitment and instructing immunosuppressive SPP1+ macrophages
errNature Genetics
IF29
err2025-11-07
err0
PREAI
errAna Henriques; Maria Salvany-Celades; Paula Nieto; Sergio Palomo-Ponce; Marta Sevillano; Xavier Hernando-Momblona; Emily Middendorp-Guerra; Montserrat Llanses Martinez; Elisabeth Marjolein Haak; Juan Nieto; Ginevra Caratú; Domenica Marchese; Max Ruiz Gil; Sebastien Tosi; Theresa Suckert; Jordi Badia-Ramentol; Adrià Caballé-Mestres; Carolina Sanchez-Zarzalejo; Lidia Mateo; Daniele V. F. Tauriello; Antoni Riera; Elena Sancho; Camille Stephan-Otto Attolini; Alejandro Prados; Holger Heyn; Eduard Batlle
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errSave
Uncovering combination therapies for Immune-Mediated Inflammatory Diseases through systems biology analysis on longitudinal patient data
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errJuli, Antonio; Lasanta, Maria Lopez; Choy, Ernest; Vela-Casasempere, Paloma; Castaneda, Santos; Fernandez Nebro, Antonio; Calvo-Alen, Jaime; Marras, Carlos; Tornero, Jesus; Canete, Juan D.; Domenech, Eugeni; Gisbert, Javier; Carrascosa, Jose Manuel; Fonseca, Eduardo; Bujanda, Luis; Garcia, Valle; Siegmund, Britta; Girolomoni, Giampiero; Heyn, Holger; Santamaria, Pere; Myers, Richard; Guillen, Yolanda; Martinez-Mateu, Sergio H.; Marsal, Sara
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errSave
A IMMUNOMODULATORY EFFECTS OF PREOPERATIVE STEREOTACTIC RADIOSURGERY IN BRAIN METASTASES: PROSPECTIVE INTEGRATION OF TISSUE AND CEREBROSPINAL FLUID PROFILING
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errSteinhauser, E.; Klinsing, S.; Borkus, I; Schaeffer, A.; Nieto, P.; Vogt, I; Diehl, B.; Broggini, T.; Czabanka, M.; Plate, K.; Harter, P.; Wolff, R.; Wenger-Alakmeh, K.; Reiss, Y.; Imkeller, K.; Luger, A.; Heyn, H.; Medyouf, H.; Nieto, J. C.; Weber, K. J.; Steinbach, J.; Zeiner, P. S.
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errSave
HNF1A and A1CF coordinate a beta cell transcription-splicing axis that is disrupted in type 2 diabetes
errCell Metabolism
IF30.9
err2025-08-06
err0
errOAAI
errEdgar Bernardo; Matías Gonzalo De Vas; Diego Balboa; Mirabai Cuenca-Ardura; Sílvia Bonàs-Guarch; Mercè Planas-Fèlix; Fanny Mollandin; Miquel Torrens-Dinarès; Miguel Angel Maestro; Javier García-Hurtado; Sonia Moratinos; Philippe Ravassard; Haiqiang Dou; Holger Heyn; Alexander van Oudenaarden; Nathalie Groen; Eelco de Koning; Christian Conrad; Roland Eils; Santiago Vernia; Patrik Rorsman; Jorge Ferrer
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errSave
Single-cell RNA-sequencing as a potential approach for studying intratumor heterogeneity in pleural mesothelioma
errLung Cancer
IF4.4
err2025-08-05
err0
PREAI
errAnia Alay; Raúl Marín; Elisabet Aliagas; Mireia Gausachs; Max Ruiz-Gil; Ivan Macia; Amaia Ojanguren; Susana Padrones; Eduard Dorca; Jesús Brenes; Ramón Palmero; Víctor Moreno; Holger Heyn; David Cordero; Ernest Nadal; Xavier Solé
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errSave
STAMP: Single-cell transcriptomics analysis and multimodal profiling through imaging
errCell
IF42.5
err2025-06-17
err0
errOAAI
errEmanuele Pitino; Anna Pascual-Reguant; Felipe Segato-Dezem; Kellie Wise; Irepan Salvador-Martinez; Helena Lucia Crowell; Maycon Marção; Max Ruiz; Elise Courtois; William F. Flynn; Santhosh Sivajothi; Emily Soja; Ginevra Caratù; German Atzin Mora-Roldan; B. Kate Dredge; Yutian Liu; Hannah Chasteen; Monika Mohenska; Juan C. Nieto; Raymond K.H. Yip; Ruvimbo D. Mishi; José M. Polo; Mohmed Abdalfttah; Adrienne E. Sullivan; Jasmine T. Plummer; Holger Heyn; Luciano G. Martelotto
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errSave
Spatiotemporal T-cell tracking for personalized T-cell receptor T-cell therapy designs in childhood cancer
errAnnals of Oncology
IF65.4
err2025-05-20
err0
errOAAI
errI. Sentís; J.L. Melero; A. Cebria-Xart; M. Grzelak; M. Soto; A. Michel; Q. Rovira; C.J. Rodriguez-Hernandez; G. Caratù; A. Urpi; C. Sauvage; A. Mendizabal-Sasieta; D. Maspero; C.E. Lavarino; A. Pascual-Reguant; A. Castañeda Heredia; J.P. Muñoz Perez; J. Mora; A. Harari; J.C. Nieto; A. Avgustinova; H. Heyn
errShare
errSave
Transcriptional reprogramming triggered by neonatal UV radiation or Lkb1 loss prevents BRAFV600E-induced growth arrest in melanocytes
errONCOGENE
IF7.3
err2025-03-08
err0
errOAAI
errMcgrail, Kimberley; Granado-Martinez, Paula; Orsenigo, Roberto; Caratu, Ginevra; Nieto, Paula; Heyn, Holger; Ferrer, Berta; Hernandez-Losa, Javier; Munoz-Couselo, Eva; Garcia-Patos, Vicenc; Recio, Juan A.
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errSave
Linking tumor immune infiltration to enhanced longevity in recurrence-free breast cancer
errESMO OPEN
IF8.3
err2025-01-01
err0
errOAAI
errAngelats, L.; Pare, L.; Rubio-Perez, C.; Sanfeliu, E.; Gonzalez, A.; Segui, E.; Villacampa, G.; Marin-Aguilera, M.; Pernas, S.; Conte, B.; Albarran-Fernandez, V.; Martinez-Saez, O.; Aguirre, A.; Galvan, P.; Fernandez-Martinez, A.; Cobo, S.; Rey, M.; Martinez-Romero, A.; Walbaum, B.; Schettini, F.; Vidal, M.; Buckingham, W.; Munoz, M.; Adamo, B.; Agrawal, Y.; Guedan, S.; Pascual, T.; Agudo, J.; Grzelak, M.; Borcherding, N.; Heyn, H.; Vivancos, A.; Parker, J. S.; Villagrasa, P.; Perou, C. M.; Prat, A.; Braso-Maristany, F.
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errSave
Adaptation in human immune cells residing in tissues at the frontline of infections
errNATURE COMMUNICATIONS
IF15.7
err2024-11-28
err0
errOAAI
errSalvador-Martinez, Irepan; Murga-Moreno, Jesus; Nieto, Juan C.; Alsinet, Clara; Enard, David; Heyn, Holger
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errSave
Albumin reprograms the B cell transcriptional landscape and improves neutrophil antimicrobial function in patients with decompensated cirrhosis
errJHEP REPORTS
IF7.5
err2024-11-01
err0
errOAAI
errClaria, Joan; Aguilar, Ferran; Lozano, Juan-Jose; Jimenez-Gracia, Laura; Nieto, Juan C.; Romero-Grimaldo, Berta; Marcos-Fa, Xavi; Giarracco, Emma; Weiss, Emmanuel; Trebicka, Jonel; Hernandez, Inmaculada; Fernandez, Javier; Casulleras, Mireia; Lopez-Vicario, Cristina; Muldur, Sinan; Hopke, Alex; Vlagea, Alexandru; Aransay, Ana M.; Marchese, Domenica; Bernardi, Mauro; Jalan, Rajiv; Angeli, Paolo; Magri, Giuliana; Cerutti, Andrea; Irimia, Daniel; Heyn, Holger; Arroyo, Vicente; Moreau, Richard
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errSave
Integrative single-cell multi-omics of CD19-CARpos and CARneg T cells suggest drivers of immunotherapy response in B cell neoplasias
errCELL REPORTS MEDICINE
IF10.6
err2024-11-01
err0
errOAAI
errGuerrero-Murillo, Mercedes; Rill-Hinarejos, Aina; Trincado, Juan L.; Bataller, Alex; Ortiz-Maldonado, Valentin; Benitez-Ribas, Daniel; Espanol-Rego, Marta; Gonzalez-Navarro, Eazucena; Martinez-Cibrian, Nuria; Marchese, Domenica; Martin-Martin, Lourdes; Garcia-Sancho, Alejandro Martin; Rives, Susana; Heyn, Holger; Juan, Manel; Urbano-Ispizua, Alvaro; Delgado, Julio; Orfao, Alberto; Mereu, Elisabetta; Bueno, Clara; Menendez, Pablo
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errSave
Impact of B cell and plasma cell infiltration on survival in early-stage breast cancer (BC) without recurrence
errANNALS OF ONCOLOGY
IF65.4
err2024-09-01
err0
PREAI
errAngelats, L.; Brunet, L. Pare; Rubio-Perez, C.; Torres, E. Sanfeliu; Solis, E. Segui; Villacampa, G.; Marin, M.; Conte, B.; Saez, O. Martinez; Fernandez-Martinez, A.; Buckingham, W.; Guedan, S.; Heyn, H.; Vivancos, A.; Parker, J.; Gonzalez, P. Villagrasa; Perou, C. M.; Prat, A.; Maristany, F. Braso
errShare
errSave
Liquid biopsy tracking of immunotherapy-induced T cell dynamics in MSS colorectal and endometrial tumors
errANNALS OF ONCOLOGY
IF65.4
err2024-09-01
err0
PREAI
errHeyn, H.; Melero, J. L.; Deuner, G.; Baraibar Argota, I.; Grzelak, M.; Caratu, G.; Garcia Duran, C.; Grau Bejar, J. F.; Illescas, D. G.; Farinas Madrid, L.; Nieto, P.; Morabito, S.; Rotem, A.; Casbas-Hernandez, P.; Gros, A.; Tabernero, J.; Oaknin, A.; Sachica, J. N.; Borcherding, N.; Elez Fernandez, M. E.
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errSave
Decoding the muscle transcriptome of patients with late-onset Pompe disease reveals markers of disease progression
errBRAIN
IF11.7
err2024-07-24
err0
errOAAI
errMonceau, Alexandra; Nath, Rasya Gokul; Suarez-Calvet, Xavier; Musumeci, Olimpia; Toscano, Antonio; Kierdaszuk, Biruta; Kostera-Pruszczyk, Anna; Dominguez-Gonzalez, Cristina; Hernandez-Lain, Aurelio; Paradas, Carmen; Rivas, Eloy; Papadimas, George; Papadopoulos, Constantinos; Chrysanthou-Piterou, Margarita; Gallardo, Eduard; Olive, Montse; Lilleker, James; Roberts, Mark E.; Marchese, Domenica; Lunazzi, Giulia; Heyn, Holger; Fernandez-Simon, Esther; Villalobos, Elisa; Clark, James; Katsikis, Panos; Collins, Catherine; Mehra, Priyanka; Laidler, Zoe; Vincent, Amy; Tasca, Giorgio; Marini-Bettolo, Chiara; Guglieri, Michela; Straub, Volker; Raben, Nina; Diaz-Manera, Jordi
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errSave
Unraveling the molecular architecture of autoimmune thyroid diseases at spatial resolution
errNATURE COMMUNICATIONS
IF15.7
err2024-07-13
err0
errOAAI
errMartinez-Hernandez, Rebeca; de la Blanca, Nuria Sanchez; Sacristan-Gomez, Pablo; Serrano-Somavilla, Ana; De Nova, Jose Luis Munoz; Cabo, Fatima Sanchez; Heyn, Holger; Sampedro-Nunez, Miguel; Marazuela, Monica
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errSave

Research Directions

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Co-authors
Cooperation Journals
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