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U

Utpal B. Pajvani

columbia university

42H-index
98Paper Count
1.3WCitation Count
Published Papers 65
Publication Date
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TGFβ activity stabilizes ACC1 to increase de novo lipogenesis in metabolic liver disease
errMolecular Metabolism
IF6.6
err2026-06-01
err0
errOAAI
errBrent Mayfield; Yoko Yagashita; Jinku Kang; Changyu Zhu; Stefania Mira; Timothy J. Kendall; Qiuyan Sun; Maria E. Meincke; Domenick Raphael; Meng Li; Shuxuan Chen; Harrison Cullen; Stryder M. Meadows; Luke E. Berchowitz; Michele Carrer; Jonathan A. Fallowfield; Robert F. Schwabe; Luca Valenti; Utpal B. Pajvani
errShare
errSave
Characteristics of Transient Elastography for Hepatic Steatosis and Fibrosis in Children Undergoing Liver Biopsy
errThe Journal of Pediatrics
IF3.5
err2026-04-17
err0
PREAI
errJonathan B. Steinman; Ngoc Duong; Ivette Partida; Celine Bien-Aime; Wei Shen; Christine K. Lee; Ladan A. Fazlollahi; Helen E. Remotti; Utpal B. Pajvani; Jeff Goldsmith; Jennifer A. Woo Baidal
errShare
errSave
Unraveling A-β plus ketosis-prone diabetes: An evolving diagnosis with an elusive pathogenesis
errJournal of Diabetes Investigation
IF3
err2026-01-01
err0
errOAAI
errSuda, Nina; Page-wilson, Gabrielle; Lonier, Jacqueline; Pajvani, Utpal B.
errShare
errSave
Hepatocyte KCTD17-mediated SERPINA3 inhibition determines liver fibrosis in metabolic dysfunction-associated steatohepatitis
errExperimental & Molecular Medicine
IF12.9
err2025-08-01
err0
errOAAI
errYelin Jeong; Ah-Reum Oh; Young Hoon Jung; Kyung Hee Jung; Seongju Lee; Michele Carrer; Sang Bae Lee; Luca Valenti; Utpal B. Pajvani; KyeongJin Kim
errShare
errSave
Notch1 Signalling Is Downregulated by Aerobic Exercise, Leading to Improvement of Hepatic Metabolism in Obese Mice
errLIVER INTERNATIONAL
IF5.2
err2025-03-13
err0
PREAI
errGaspar, Rafael Calais; Macedo, Ana Paula Azevedo; Nakandakari, Susana Castelo Branco Ramos; Munoz, Vitor Rosetto; Abud, Gabriela Ferreira; Vieira, Renan Fudoli Lins; de Sousa Neto, Ivo Vieira; Pavan, Isadora Carolina Betim; da Silva, Luiz Guilherme Salvino; Simabuco, Fernando Moreira; da Silva, Adelino S. R.; Salgado Jr, Wilson Salgado; Marchini, Julio Sergio; Nonino, Carla Barbosa; Cintra, Dennys Esper; Ropelle, Eduardo Rochete; Pajvani, Utpal B.; de Freitas, Ellen Cristini; Pauli, Jose Rodrigo
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errSave
Kisspeptin Alleviates Human Hepatic Fibrogenesis by Inhibiting TGFβ Signaling in Hepatic Stellate Cells
errCELLS
IF5.2
err2024-10-04
err0
errOAAI
errPrasad, Kavita; Bhattacharya, Dipankar; Shams, Shams Gamal Eldin; Izarraras, Kimberly; Hart, Tia; Mayfield, Brent; Blaszczyk, Maryjka B.; Zhou, Zhongren; Pajvani, Utpal B.; Friedman, Scott L.; Bhattacharya, Moshmi
errShare
errSave
KCTD17-mediated Ras stabilization promotes hepatocellular carcinoma progression
errCLINICAL AND MOLECULAR HEPATOLOGY
IF16.9
err2024-10-01
err0
errOAAI
errJung, Young Hoon; Lee, Yun Ji; Dao, Tam; Jung, Kyung Hee; Yu, Junjie; Oh, Ah-Reum; Jeong, Yelin; Gi, Hyunjoon; Kim, Young Un; Ryu, Dongryeol; Carrer, Michele; Pajvani, Utpal B.; Lee, Sang Bae; Hong, Soon-Sun; Kim, Kyeongjin
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errSave
Calorie restriction activates a gastric Notch-FOXO1 pathway to expand ghrelin cells
errJOURNAL OF CELL BIOLOGY
IF6.4
err2024-07-03
err0
errOAAI
errMcKimpson, Wendy M.; Spiegel, Sophia; Mukhanova, Maria; Kraakman, Michael; Du, Wen; Kitamoto, Takumi; Yu, Junjie; Deng, Zhaobin; Pajvani, Utpal; Accili, Domenico
errShare
errSave
The first MASH drug therapy on the horizon: Current perspectives of resmetirom
errLIVER INTERNATIONAL
IF5.2
err2024-04-05
err52
errOAAI
errPetta, Salvatore; Targher, Giovanni; Romeo, Stefano; Pajvani, Utpal B.; Zheng, Ming-Hua; Aghemo, Alessio; Valenti, Luca V. C.
errShare
errSave
Protective hepatocyte signals restrain liver fibrosis in metabolic dysfunction-associated steatohepatitis
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2024-04-01
err1
errOAAI
errSteffani, Marcella; Geng, Yana; Pajvani, Utpal B.; Schwabe, Robert F.
errShare
errSave
(3-cell Jagged1 is sufficient but not necessary for islet Notch activity and insulin secretory defects in obese mice
errMOLECULAR METABOLISM
IF6.6
err2024-03-01
err0
errOAAI
errSuda, Nina; Bartolome, Alberto; Liang, Jiani; Son, Jinsook; Yagishita, Yoko; Siebel, Christian; Accili, Domenico; Ding, Hongxu; Pajvani, Utpal B.
errShare
errSave
Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner (17, 8, 2011)
errNATURE MEDICINE
IF50
err2023-12-01
err0
errOAAI
errPajvani, Utpal B.; Shawber, Carrie J.; Samuel, Varman T.; Birkenfeld, Andreas L.; Shulman, Gerald I.; Kitajewski, Jan; Accili, Domenico
errShare
errSave
Liver insulinization as a driver of triglyceride dysmetabolism
errNATURE METABOLISM
IF20.8
err2023-07-17
err10
PREAI
errCook, Joshua R.; Hawkins, Meredith A.; Pajvani, Utpal B.
errShare
errSave
Integrating stress signals-XBP1 as a novel mediator of intercellular crosstalk in non-alcoholic steatohepatitis
errTRANSLATIONAL GASTROENTEROLOGY AND HEPATOLOGY
IF2.5
err2023-04-01
err2
errOAAI
errYu, Junjie; Pajvani, Utpal B.
errShare
errSave
MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-17
err105
errOAAI
errBartolome, Alberto; Garcia-Aguilar, Ana; Asahara, Shun-Ichiro; Kido, Yoshiaki; Guillen, Carlos; Pajvani, Utpal B.; Benito, Manuel
errShare
errSave
Hepatocyte Kctd17 Inhibition Ameliorates Glucose Intolerance and Hepatic Steatosis Caused by Obesity-induced Chrebp Stabilization
errGASTROENTEROLOGY
IF25.1
err2023-03-01
err10
errOAAI
errOh, Ah-Reum; Jeong, Yelin; Yu, Junjie; Tam, Dao Thi Minh; Kang, Jin Ku; Jung, Young Hoon; Im, Seung-Soon; Lee, Sang Bae; Ryu, Dongryeol; Pajvani, Utpal B.; Kim, KyeongJin
errShare
errSave
Notch-mediated hepatocyte MCP-1 secretion causes liver fibrosis
errJCI INSIGHT
IF6.1
err2023-02-08
err31
errOAAI
errKang, Jinku; Postigo-Fernandez, Jorge; Kim, KyeongJin; Zhu, Changyu; Yu, Junjie; Meroni, Marica; Mayfield, Brent; Bartolome, Alberto; Dapito, Dianne H.; Ferrante, Anthony W., Jr.; Dongiovanni, Paola; Valenti, Luca; Creusot, Remi J.; Pajvani, Utpal B.
errShare
errSave
PPARγ Acetylation Orchestrates Adipose Plasticity and Metabolic Rhythms
errADVANCED SCIENCE
IF14.1
err2022-11-17
err25
errOAAI
errHe, Ying; Taub, Alana B'nai; Yu, Lexiang; Yao, Yifan; Zhang, Ruotong; Zahr, Tarik; Aaron, Nicole; LeSauter, Joseph; Fan, Lihong; Liu, Longhua; Tazebay, Ruya; Que, Jianwen; Pajvani, Utpal; Wang, Liheng; Silver, Rae; Qiang, Li
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errSave
An Overfeeding-Induced Obesity Mouse Model Reveals Necessity for Sin3a in Postnatal Peak β-Cell Mass Acquisition
errDIABETES
IF7.5
err2022-08-09
err2
errOAAI
errBartolome, Alberto; Ravussin, Yann; Yu, Junjie; Ferrante, Anthony W., Jr.; Pajvani, Utpal B.
errShare
errSave
TAZ-induced Cybb contributes to liver tumor formation in non-alcoholic steatohepatitis
errJOURNAL OF HEPATOLOGY
IF33
err2022-04-01
err31
errOAAI
errWang, Xiaobo; Zeldin, Sharon; Shi, Hongxue; Zhu, Changyu; Saito, Yoshinobu; Corey, Kathleen E.; Osganian, Stephanie A.; Remotti, Helen E.; Verna, Elizabeth C.; Pajvani, Utpal B.; Schwabe, Robert F.; Tabas, Ira
errShare
errSave

Research Directions

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Co-authors
Cooperation Journals
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Pierre Chambon
H-index: 207 · Papers: 844
J
Johan Auwerx
H-index: 183 · Papers: 913
G
Gerald I. Shulman
H-index: 183 · Papers: 819
K
Kun‐Liang Guan
H-index: 168 · Papers: 621
S
Scott W. Lowe
H-index: 156 · Papers: 977
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