Not logged in Evaluation of Polygenic Risk Scores for a Possible Genetic Basis of the Inverse Association Between Cancer and Cognitive Decline Graff, Rebecca E.; Chen, Dorothy M.; Swinnerton, Kaitlin N.; Ackley, Sarah F.; Ospina-Romero, Monica; Zimmerman, Scott C.; Wang, Jingxuan; Buto, Peter; Nierenberg, Jovia L.; Elahi, Fanny M.; Lu, Kun Ping; Witte, John S.; Glymour, M. Maria Share Save
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Unraveling the genetic landscape of susceptibility to multiple primary cancers Middha, Pooja; Kachuri, Linda; Nierenberg, Jovia L.; Graff, Rebecca E.; Cavazos, Taylor B.; Hoffmann, Thomas J.; Zhang, Jie; Alexeeff, Stacey; Habel, Laurel; Corley, Douglas A.; van den Eeden, Stephen; Kushi, Lawrence H.; Ziv, Elad; Sakoda, Lori C.; Witte, John S. Share Save
SLCO1B1 Functional Variants, Bilirubin, Statin-Induced Myotoxicity, and Recent Sub-Saharan African Ancestry: A Precision Medicine Health Equity Study Haldar, Tanushree; Kvale, Mark; Yang, Jia; Douglas, Michael P.; Coyote-Maetas, Willow; Kachuri, Linda; Witte, John S.; Iribarren, Carlos; Medina, Marisa W.; Krauss, Ronald M.; Yee, Sook Wah; Oni-Orisan, Akinyemi Share Save
The PRIMED Consortium: Reducing disparities in polygenic risk assessment Kullo, Iftikhar J.; Conomos, Matthew P.; Nelson, Sarah C.; Adebamowo, Sally N.; Choudhury, Ananyo; Conti, David; Fullerton, Stephanie M.; Gogarten, Stephanie M.; Heavner, Ben; Hornsby, Whitney E.; Kenny, Eimear E.; Khan, Alyna; Khera, Amit V.; Li, Yun; Martin, Iman; Mercader, Josep M.; Ng, Maggie; Raffield, Laura M.; Reiner, Alex; Rowley, Robb; Schaid, Daniel; Stilp, Adrienne; Wiley, Ken; Wilson, Riley; Witte, John S.; Natarajan, Pradeep Share Save
The full spectrum of SLC22 OCT1 mutations illuminates the bridge between drug transporter biophysics and pharmacogenomics Yee, Sook Wah; Macdonald, Christian B.; Mitrovic, Darko; Zhou, Xujia; Koleske, Megan L.; Yang, Jia; Silva, Dina Buitrago; Grimes, Patrick Rockefeller; Trinidad, Donovan D.; More, Swati S.; Kachuri, Linda; Witte, John S.; Delemotte, Lucie; Giacomini, Kathleen M.; Coyote-Maestas, Willow Share Save
Polygenic risk score associated with risk of upgrading and tumor features in a prospective cohort of prostate cancer patients on active surveillance Goss, Louisa B.; Liu, Menghan; Zheng, Yingye; Guo, Boya; Conti, David V.; Haiman, Christopher A.; Catalona, William J.; Witte, John S.; Lin, Daniel W.; Newcomb, Lisa F.; Darst, Burcu F. Share Save
Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants Wang, Anqi; Shen, Jiayi; Rodriguez, Alex A.; Saunders, Edward J.; Chen, Fei; Janivara, Rohini; Darst, Burcu F.; Sheng, Xin; Xu, Yili; Chou, Alisha J.; Benlloch, Sara; Dadaev, Tokhir; Brook, Mark N.; Plym, Anna; Sahimi, Ali; Hoffman, Thomas J.; Takahashi, Atushi; Matsuda, Koichi; Momozawa, Yukihide; Fujita, Masashi; Laisk, Triin; Figueredo, Jessica; Muir, Kenneth; Ito, Shuji; Liu, Xiaoxi; Uchio, Yuji; Kubo, Michiaki; Kamatani, Yoichiro; Lophatananon, Artitaya; Wan, Peggy; Andrews, Caroline; Lori, Adriana; Choudhury, Parichoy P.; Schleutker, Johanna; Tammela, Teuvo L. J.; Sipeky, Csilla; Auvinen, Anssi; Giles, Graham G.; Southey, Melissa C.; MacInnis, Robert J.; Cybulski, Cezary; Wokolorczyk, Dominika; Lubinski, Jan; Rentsch, Christopher T.; Cho, Kelly; Mcmahon, Benjamin H.; Neal, David E.; Donovan, Jenny L.; Hamdy, Freddie C.; Martin, Richard M.; Nordestgaard, Borge G.; Nielsen, Sune F.; Weischer, Maren; Bojesen, Stig E.; Roder, Andreas; Stroomberg, Hein V.; Batra, Jyotsna; Chambers, Suzanne; Horvath, Lisa; Clements, Judith A.; Tilly, Wayne; Risbridger, Gail P.; Gronberg, Henrik; Aly, Markus; Szulkin, Robert; Eklund, Martin; Nordstrom, Tobias; Pashayan, Nora; Dunning, Alison M.; Ghoussaini, Maya; Travis, Ruth C.; Key, Tim J.; Riboli, Elio; Park, Jong Y.; Sellers, Thomas A.; Lin, Hui-Yi; Albanes, Demetrius; Weinstein, Stephanie; Cook, Michael B.; Mucci, Lorelei A.; Giovannucci, Edward; Lindstrom, Sara; Kraft, Peter; Hunter, David J.; Penney, Kathryn L.; Turman, Constance; Tangen, Catherine M.; Goodman, Phyllis J.; Thompson, Ian M., Jr.; Hamilton, Robert J.; Fleshner, Neil E.; Finelli, Antonio; Parent, Marie-Elise; Stanford, Janet L.; Ostrander, Elaine A.; Koutros, Stella; Freeman, Laura E. Beane; Stampfer, Meir; Wolk, Alicja; Hakansson, Niclas; Andriole, Gerald L.; Hoover, Robert N.; Machiela, Mitchell J.; Sorensen, Karina Dalsgaard; Borre, Michael; Blot, William J.; Zheng, Wei; Yeboah, Edward D.; Mensah, James E.; Lu, Yong-Jie; Zhang, Hong-Wei; Feng, Ninghan; Mao, Xueying; Wu, Yudong; Zhao, Shan-Chao; Sun, Zan; Thibodeau, Stephen N.; McDonnell, Shannon K.; Schaid, Daniel J.; West, Catharine M. L.; Barnett, Gill; Maier, Christiane; Schnoeller, Thomas; Luedeke, Manuel; Kibel, Adam S.; Drake, Bettina F.; Cussenot, Olivier; Cancel-Tassin, Geraldine; Menegaux, Florence; Truong, Therese; Koudou, Yves Akoli; John, Esther M.; Grindedal, Eli Marie; Maehle, Lovise; Khaw, Kay-Tee; Ingles, Sue A.; Stern, Mariana C.; Vega, Ana; Gomez-Caamano, Antonio; Fachal, Laura; Rosenstein, Barry S.; Kerns, Sarah L.; Ostrer, Harry; Teixeira, Manuel R.; Paulo, Paula; Brandao, Andreia; Watya, Stephen; Lubwama, Alexander; Bensen, Jeannette T.; Butler, Ebonee N.; Mohler, James L.; Taylor, Jack A.; Kogevinas, Manolis; Dierssen-Sotos, Trinidad; Castano-Vinyals, Gemma; Cannon-Albright, Lisa; Teerlink, Craig C.; Huff, Chad D.; Pilie, Patrick; Yu, Yao; Bohlender, Ryan J.; Gu, Jian; Strom, Sara S.; Multigner, Luc; Blanchet, Pascal; Brureau, Laurent; Kaneva, Radka; Slavov, Chavdar; Mitev, Vanio; Leach, Robin J.; Brenner, Hermann; Chen, Xuechen; Holleczek, Bernd; Schoettker, Ben; Klein, Eric A.; Hsing, Ann W.; Kittles, Rick A.; Murphy, Adam B.; Logothetis, Christopher J.; Kim, Jeri; Neuhausen, Susan L.; Steele, Linda; Ding, Yuan Chun; Isaacs, William B.; Nemesure, Barbara; Hennis, Anselm J. M.; Carpten, John; Pandha, Hardev; Michael, Agnieszka; De Ruyck, Kim; De Meerleer, Gert; Ost, Piet; Xu, Jianfeng; Razack, Azad; Lim, Jasmine; Teo, Soo-Hwang; Newcomb, Lisa F.; Lin, Daniel W.; Fowke, Jay H.; Neslund-Dudas, Christine M.; Rybicki, Benjamin A.; Gamulin, Marija; Lessel, Davor; Kulis, Tomislav; Usmani, Nawaid; Abraham, Aswin; Singhal, Sandeep; Parliament, Matthew; Claessens, Frank; Joniau, Steven; Van den Broeck, Thomas; Gago-Dominguez, Manuela; Castelao, Jose Esteban; Martinez, Maria Elena; Larkin, Samantha; Townsend, Paul A.; Aukim-Hastie, Claire; Bush, William S.; Aldrich, Melinda C.; Crawford, Dana C.; Srivastava, Shiv; Cullen, Jennifer; Petrovics, Gyorgy; Casey, Graham; Wang, Ying; Tettey, Yao; Lachance, Joseph; Tang, Wei; Biritwum, Richard B.; Adjei, Andrew A.; Tay, Evelyn; Truelove, Ann; Niwa, Shelley; Yamoah, Kosj; Govindasami, Koveela; Chokkalingam, Anand P.; Keaton, Jacob M.; Hellwege, Jacklyn N.; Clark, Peter E.; Jalloh, Mohamed; Gueye, Serigne M.; Niang, Lamine; Ogunbiyi, Olufemi; Shittu, Olayiwola; Amodu, Olukemi; Adebiyi, Akindele O.; Aisuodionoe-Shadrach, Oseremen I.; Ajibola, Hafees O.; Jamda, Mustapha A.; Oluwole, Olabode P.; Nwegbu, Maxwell; Adusei, Ben; Mante, Sunny; Darkwa-Abrahams, Afua; Diop, Halimatou; Gundell, Susan M.; Roobol, Monique J.; Jenster, Guido; van Schaik, Ron H. N.; Hu, Jennifer J.; Sanderson, Maureen; Kachuri, Linda; Varma, Rohit; McKean-Cowdin, Roberta; Torres, Mina; Preuss, Michael H.; Loos, Ruth J. F.; Zawistowski, Matthew; Zollner, Sebastian; Lu, Zeyun; Van Den Eeden, Stephen K.; Easton, Douglas F.; Ambs, Stefan; Edwards, Todd L.; Magi, Reedik; Rebbeck, Timothy R.; Fritsche, Lars; Chanock, Stephen J.; Berndt, Sonja I.; Wiklund, Fredrik; Nakagawa, Hidewaki; Witte, John S.; Gaziano, J. Michael; Justice, Amy C.; Mancuso, Nick; Terao, Chikashi; Eeles, Rosalind A.; Kote-Jarai, Zsofia; Madduri, Ravi K.; Conti, David V.; Haiman, Christopher A. Share Save
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Quantitative analysis of MGMT promoter methylation in glioblastoma suggests nonlinear prognostic effect Gibson, David; Ravi, Akshay; Rodriguez, Eduardo; Chang, Susan; Bush, Nancy Oberheim; Taylor, Jennie; Clarke, Jennifer; Solomon, David; Scheffler, Aaron; Witte, John; Lambing, Hannah; Okada, Hideho; Berger, Mitchel; Chehab, Farid; Butowski, Nicholas A. Share Save
Principles and methods for transferring polygenic risk scores across global populations Kachuri, Linda; Chatterjee, Nilanjan; Hirbo, Jibril; Schaid, Daniel J.; Martin, Iman; Kullo, Iftikhar J.; Kenny, Eimear E.; Pasaniuc, Bogdan; Witte, John S.; Ge, Tian; Auer, Paul L.; Chatterjee, Nilanjan; Conomos, Matthew P.; Conti, David V.; Ding, Yi; Kachuri, Linda; Wang, Ying; Zhang, Haoyu; Zhang, Yuji Share Save
Genetically adjusted PSA levels for prostate cancer screening Kachuri, Linda; Hoffmann, Thomas J.; Jiang, Yu; Berndt, Sonja I.; Shelley, John P.; Schaffer, Kerry R.; Machiela, Mitchell J.; Freedman, Neal D.; Huang, Wen-Yi; Li, Shengchao A.; Easterlin, Ryder; Goodman, Phyllis J.; Till, Cathee; Thompson, Ian; Lilja, Hans; Van Den Eeden, Stephen K.; Chanock, Stephen J.; Haiman, Christopher A.; Conti, David V.; Klein, Robert J.; Mosley, Jonathan D.; Graff, Rebecca E.; Witte, John S. Share Save
Development and testing of a polygenic risk score for breast cancer aggressiveness Shieh, Yiwey; Roger, Jacquelyn; Yau, Christina; Wolf, Denise M.; Hirst, Gillian L.; Swigart, Lamorna Brown; Huntsman, Scott; Hu, Donglei; Nierenberg, Jovia L.; Middha, Pooja; Heise, Rachel S.; Shi, Yushu; Kachuri, Linda; Zhu, Qianqian; Yao, Song; Ambrosone, Christine B.; Kwan, Marilyn L.; Caan, Bette J.; Witte, John S.; Kushi, Lawrence H.; van 't Veer, Laura; Esserman, Laura J.; Ziv, Elad Share Save
Use of Monitoring Tests Among Patients With Localized Prostate Cancer Managed With Observation Leapman, Michael S.; Wang, Rong; Loeb, Stacy; Seibert, Tyler M.; Gaylis, Franklin D.; Lowentritt, Ben; Brown, Gordon A.; Chen, Ronald; Lin, Daniel; Witte, John; Cooperberg, Matthew R.; Catalona, William J.; Gross, Cary P.; Ma, Xiaomei Share Save
Genetic Analysis of Lung Cancer and the Germline Impact on Somatic Mutation Burden Gabriel, Aurelie A. G.; Atkins, Joshua R.; Penha, Ricardo C. C.; Smith-Byrne, Karl; Gaborieau, Valerie; Voegele, Catherine; Abedi-Ardekani, Behnoush; Milojevic, Maja; Olaso, Robert; Meyer, Vincent; Boland, Anne; Deleuze, Jean Francois; Zaridze, David; Mukeriya, Anush; Swiatkowska, Beata; Janout, Vladimir; Schejbalova, Miriam; Mates, Dana; Stojsic, Jelena; Ognjanovic, Miodrag; Witte, John S.; Rashkin, Sara R.; Kachuri, Linda; Hung, Rayjean J.; Kar, Siddhartha; Brennan, Paul; Sertier, Anne-Sophie; Ferrari, Anthony; Viari, Alain; Johansson, Mattias; Amos, Christopher, I; Foll, Matthieu; McKay, James D. Share Save
Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas. Diabetes Care 2021;44:2673-2682 Dawed, Adem Y.; Yee, Sook Wah; Zhou, Kaixin; van Leeuwen, Nienke; Zhang, Yanfei; Siddiqui, Moneeza K.; Etheridge, Amy; Innocenti, Federico; Xu, Fei; Li, Josephine H.; Beulens, Joline W.; van der Heijden, Amber A.; Slieker, Roderick C.; Chang, Yu-Chuan; Mercader, Josep M.; Kaur, Varinderpal; Witte, John S.; Lee, Ming Ta Michael; Kamatani, Yoichiro; Momozawa, Yukihide; Kubo, Michiaki; Palmer, Colin N. A.; Florez, Jose C.; Hedderson, Monique M.; 't Hart, Leen M.; Giacomini, Kathleen M.; Pearson, Ewan R. Share Save
Association Between a 22-feature Genomic Classifier and Biopsy Gleason Upgrade During Active Surveillance for Prostate Cancer Press, Benjamin H.; Jones, Tashzna; Olawoyin, Olamide; Lokeshwar, Soum D.; Rahman, Syed N.; Khajir, Ghazal; Lin, Daniel W.; Cooperberg, Matthew R.; Loeb, Stacy; Darst, Burcu F.; Zheng, Yingye; Chen, Ronald C.; Witte, John S.; Seibert, Tyler M.; Catalona, William J.; Leapman, Michael S.; Sprenkle, Preston C. Share Save
Genetic factors associated with prostate cancer conversion from active surveillance to treatment Jiang, Yu; Meyers, Travis J.; Emeka, Adaeze A.; Cooley, Lauren Folgosa; Cooper, Phillip R.; Lancki, Nicola; Helenowski, Irene; Kachuri, Linda; Lin, Daniel W.; Stanford, Janet L.; Newcomb, Lisa F.; Kolb, Suzanne; Finelli, Antonio; Fleshner, Neil E.; Komisarenko, Maria; Eastham, James A.; Ehdaie, Behfar; Benfante, Nicole; Logothetis, Christopher J.; Gregg, Justin R.; Perez, Cherie A.; Garza, Sergio; Kim, Jeri; Marks, Leonard S.; Delfin, Merdie; Barsa, Danielle; Vesprini, Danny; Klotz, Laurence H.; Loblaw, Andrew; Mamedov, Alexandre; Goldenberg, S. Larry; Higano, Celestia S.; Spillane, Maria; Wu, Eugenia; Carter, H. Ballentine; Pavlovich, Christian P.; Mamawala, Mufaddal; Landis, Tricia; Carroll, Peter R.; Chan, June M.; Cooperberg, Matthew R.; Cowan, Janet E.; Morgan, Todd M.; Siddiqui, Javed; Martin, Rabia; Klein, Eric A.; Brittain, Karen; Gotwald, Paige; Barocas, Daniel A.; Dallmer, Jeremiah R.; Gordetsky, Jennifer B.; Steele, Pam; Kundu, Shilajit D.; Stockdale, Jazmine; Roobol, Monique J.; Venderbos, Lionne D. F.; Sanda, Martin G.; Arnold, Rebecca; Patil, Dattatraya; Evans, Christopher P.; Dall'Era, Marc A.; Vij, Anjali; Costello, Anthony J.; Chow, Ken; Corcoran, Niall M.; Rais-Bahrami, Soroush; Phares, Courtney; Scherr, Douglas S.; Flynn, Thomas; Karnes, R. Jeffrey; Koch, Michael; Dhondt, Courtney Rose; Nelson, Joel B.; McBride, Dawn; Cookson, Michael S.; Stratton, Kelly L.; Farriester, Stephen; Hemken, Erin; Stadler, Walter M.; Pera, Tuula; Banionyte, Deimante; Bianco, Fernando J., Jr.; Lopez, Isabel H.; Loeb, Stacy; Taneja, Samir S.; Byrne, Nataliya; Amling, Christopher L.; Martinez, Ann; Boileau, Luc; Gaylis, Franklin D.; Petkewicz, Jacqueline; Kirwen, Nicholas; Helfand, Brian T.; Xu, Jianfeng; Scholtens, Denise M.; Catalona, William J.; Witte, John S. Share Save
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